CDK4 and CDK6 delay senescence by kinase-dependent and p16 INK4a-independent mechanisms

Molecular and Cellular Biology

Volumn 27, Issue 12, 2007, Pages 4273-4282

  Ruas, Margarida ^a,b   Gregory, Fiona ^a,c   Jones, Rebecca ^a,d   Poolman, Robert ^a,e   Starborg, Maria ^a,f   Rowe, Janice ^a   Brookes, Sharon ^a   Peters, Gordon ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Linklaters ^*  (United Kingdom)

^d VETERINARY LABORATORIES AGENCY   (United Kingdom)

^e NOVARTIS PHARMA AG   (Switzerland)

^f Swedish Research Council   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1; PROTEIN P16INK4A; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ALLELE; ARTICLE; CATALYSIS; CELL AGING; CELL CYCLE ARREST; CELL DIVISION; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FIBROBLAST; GENE; GENE MUTATION; GENE REPRESSION; HUMAN; HUMAN CELL; INK4ALPHA GENE; LIFESPAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENESCENCE;

ALLELES; CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FIBROBLASTS; HUMANS; MUTATION; RETROVIRIDAE; VARIATION (GENETICS);

EID: 34250215990     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.02286-06     Document Type: Article

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