Modeling mutations in the G1 arrest pathway in human gliomas: Overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes

Genes and Development

Volumn 12, Issue 23, 1998, Pages 3644-3649

  Holland, Eric C ^a,c   Hively, Wendy P ^a   Gallo, Vittorio ^b   Varmus, Harold E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; CDK4 PROTEIN, HUMAN; CDK4 PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 4; ONCOPROTEIN; PROTEIN; PROTEIN P14ARF; PROTEIN P16INK4A;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL CULTURE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GLIOMA; MODEL; MOUSE; NEWBORN; NONHUMAN; PLOIDY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ANIMAL; BIOSYNTHESIS; CYTOLOGY; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; TRANSGENIC MOUSE;

ANIMALS; ASTROCYTES; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; G1 PHASE; GLIOMA; HUMANS; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; PLOIDIES; PROTEINS; PROTO-ONCOGENE PROTEINS; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0032217155     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.23.3644     Document Type: Article

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