Biallelic mutations in p16INK4a confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts

Molecular and Cellular Biology

Volumn 22, Issue 23, 2002, Pages 8135-8143

  Huot, Thomas J ^a   Rowe, Janice ^a   Harland, Mark ^a   Drayton, Sarah ^a   Brookes, Sharon ^a   Gooptu, Chandra ^a   Purkis, Patricia ^a   Fried, Mike ^a   Bataille, Veronique ^a   Hara, Eiji ^a   Newton Bishop, Julia ^a   Peters, Gordon ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P16; PROTEIN P53; RAS PROTEIN; TELOMERASE; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR ETS 2;

ADULT; ALLELE; AMINO ACID SEQUENCE; ANCHORAGE INDEPENDENT GROWTH; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; EXON; FIBROBLAST; GENE LOCUS; GENE MUTATION; HUMAN; HUMAN CELL; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SENESCENCE; SEQUENCE ANALYSIS;

ADULT; ALLELES; ANIMALS; CELL AGING; CELL LINE; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; DERMIS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MALE; MELANOMA; MUTATION; PROTO-ONCOGENE PROTEIN C-ETS-1; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-ETS; RAS PROTEINS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53;

EID: 18644365331     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.23.8135-8143.2002     Document Type: Article

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