-
1
-
-
0034749999
-
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity
-
Adolfsson J., Borge O.J., Bryder D., Theilgaard-Monch K., Astrand-Grundstrom I., Sitnicka E., Sasaki Y., and Jacobsen S.E. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity 15 (2001) 659-669
-
(2001)
Immunity
, vol.15
, pp. 659-669
-
-
Adolfsson, J.1
Borge, O.J.2
Bryder, D.3
Theilgaard-Monch, K.4
Astrand-Grundstrom, I.5
Sitnicka, E.6
Sasaki, Y.7
Jacobsen, S.E.8
-
2
-
-
20244387299
-
Identification of flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
-
Adolfsson J., Mansson R., Buza-Vidas N., Hultquist A., Liuba K., Jensen C.T., Bryder D., Yang L., Borge O.J., Thoren L.A., et al. Identification of flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121 (2005) 295-306
-
(2005)
Cell
, vol.121
, pp. 295-306
-
-
Adolfsson, J.1
Mansson, R.2
Buza-Vidas, N.3
Hultquist, A.4
Liuba, K.5
Jensen, C.T.6
Bryder, D.7
Yang, L.8
Borge, O.J.9
Thoren, L.A.10
-
3
-
-
0037438387
-
Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis
-
Akashi K., He X., Chen J., Iwasaki H., Niu C., Steenhard B., Zhang J., Haug J., and Li L. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 101 (2003) 383-389
-
(2003)
Blood
, vol.101
, pp. 383-389
-
-
Akashi, K.1
He, X.2
Chen, J.3
Iwasaki, H.4
Niu, C.5
Steenhard, B.6
Zhang, J.7
Haug, J.8
Li, L.9
-
4
-
-
0031587826
-
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
-
Akashi K., Kondo M., von Freeden-Jeffry U., Murray R., and Weissman I.L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89 (1997) 1033-1041
-
(1997)
Cell
, vol.89
, pp. 1033-1041
-
-
Akashi, K.1
Kondo, M.2
von Freeden-Jeffry, U.3
Murray, R.4
Weissman, I.L.5
-
5
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi K., Traver D., Miyamoto T., and Weissman I.L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404 (2000) 193-197
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
6
-
-
17444408151
-
The complex cartography of stem cell commitment
-
Akashi K., Traver D., and Zon L.I. The complex cartography of stem cell commitment. Cell 121 (2005) 160-162
-
(2005)
Cell
, vol.121
, pp. 160-162
-
-
Akashi, K.1
Traver, D.2
Zon, L.I.3
-
7
-
-
1242274449
-
Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems
-
Angeli D., Ferrell Jr. J.E., and Sontag E.D. Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Proc. Natl. Acad. Sci. USA 101 (2004) 1822-1827
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1822-1827
-
-
Angeli, D.1
Ferrell Jr., J.E.2
Sontag, E.D.3
-
8
-
-
29144472957
-
Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis
-
Arinobu Y., Iwasaki H., Gurish M.F., Mizuno S., Shigematsu H., Ozawa H., Tenen D.G., Austen K.F., and Akashi K. Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. Proc. Natl. Acad. Sci. USA 102 (2005) 18105-18110
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 18105-18110
-
-
Arinobu, Y.1
Iwasaki, H.2
Gurish, M.F.3
Mizuno, S.4
Shigematsu, H.5
Ozawa, H.6
Tenen, D.G.7
Austen, K.F.8
Akashi, K.9
-
9
-
-
2342488710
-
PU.1 determines the self-renewal capacity of erythroid progenitor cells
-
Back J., Dierich A., Bronn C., Kastner P., and Chan S. PU.1 determines the self-renewal capacity of erythroid progenitor cells. Blood 103 (2004) 3615-3623
-
(2004)
Blood
, vol.103
, pp. 3615-3623
-
-
Back, J.1
Dierich, A.2
Bronn, C.3
Kastner, P.4
Chan, S.5
-
12
-
-
25444433301
-
Epigenetic plasticity of hematopoietic cells
-
Bonifer C. Epigenetic plasticity of hematopoietic cells. Cell Cycle 4 (2005) 211-214
-
(2005)
Cell Cycle
, vol.4
, pp. 211-214
-
-
Bonifer, C.1
-
13
-
-
0033485342
-
Lymphoid-restricted development from multipotent candidate murine stem cells: Distinct and complimentary functions of the c-kit and flt3-ligands
-
Borge O.J., Adolfsson J., and Jacobsen A.M. Lymphoid-restricted development from multipotent candidate murine stem cells: Distinct and complimentary functions of the c-kit and flt3-ligands. Blood 94 (1999) 3781-3790
-
(1999)
Blood
, vol.94
, pp. 3781-3790
-
-
Borge, O.J.1
Adolfsson, J.2
Jacobsen, A.M.3
-
14
-
-
0037047059
-
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis
-
Chang A.N., Cantor A.B., Fujiwara Y., Lodish M.B., Droho S., Crispino J.D., and Orkin S.H. GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis. Proc. Natl. Acad. Sci. USA 99 (2002) 9237-9242
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9237-9242
-
-
Chang, A.N.1
Cantor, A.B.2
Fujiwara, Y.3
Lodish, M.B.4
Droho, S.5
Crispino, J.D.6
Orkin, S.H.7
-
15
-
-
23844451378
-
Identification of mast cell progenitors in adult mice
-
Chen C.C., Grimbaldeston M.A., Tsai M., Weissman I.L., and Galli S.J. Identification of mast cell progenitors in adult mice. Proc. Natl. Acad. Sci. USA 102 (2005) 11408-11413
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11408-11413
-
-
Chen, C.C.1
Grimbaldeston, M.A.2
Tsai, M.3
Weissman, I.L.4
Galli, S.J.5
-
16
-
-
0028826488
-
PU.1 (Spi-1) autoregulates its expression in myeloid cells
-
Chen H., Ray-Gallet D., Zhang P., Hetherington C.J., Gonzalez D.A., Zhang D.E., Moreau-Gachelin F., and Tenen D.G. PU.1 (Spi-1) autoregulates its expression in myeloid cells. Oncogene 11 (1995) 1549-1560
-
(1995)
Oncogene
, vol.11
, pp. 1549-1560
-
-
Chen, H.1
Ray-Gallet, D.2
Zhang, P.3
Hetherington, C.J.4
Gonzalez, D.A.5
Zhang, D.E.6
Moreau-Gachelin, F.7
Tenen, D.G.8
-
17
-
-
0035807964
-
Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
-
Christensen J.L., and Weissman I.L. Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells. Proc. Natl. Acad. Sci. USA 98 (2001) 14541-14546
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14541-14546
-
-
Christensen, J.L.1
Weissman, I.L.2
-
18
-
-
0035353208
-
Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells
-
Colucci F., Samson S.I., DeKoter R.P., Lantz O., Singh H., and Di Santo J.P. Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells. Blood 97 (2001) 2625-2632
-
(2001)
Blood
, vol.97
, pp. 2625-2632
-
-
Colucci, F.1
Samson, S.I.2
DeKoter, R.P.3
Lantz, O.4
Singh, H.5
Di Santo, J.P.6
-
19
-
-
0032567938
-
Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor
-
Corcoran A.E., Riddell A., Krooshoop D., and Venkitaraman A.R. Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor. Nature 391 (1998) 904-907
-
(1998)
Nature
, vol.391
, pp. 904-907
-
-
Corcoran, A.E.1
Riddell, A.2
Krooshoop, D.3
Venkitaraman, A.R.4
-
20
-
-
0030838280
-
The lineage commitment of haemopoietic progenitor cells
-
Cross M.A., and Enver T. The lineage commitment of haemopoietic progenitor cells. Curr. Opin. Genet. Dev. 7 (1997) 609-613
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 609-613
-
-
Cross, M.A.1
Enver, T.2
-
21
-
-
0142124320
-
Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor
-
Dahl R., Walsh J.C., Lancki D., Laslo P., Iyer S.R., Singh H., and Simon M.C. Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat. Immunol. 4 (2003) 1029-1036
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1029-1036
-
-
Dahl, R.1
Walsh, J.C.2
Lancki, D.3
Laslo, P.4
Iyer, S.R.5
Singh, H.6
Simon, M.C.7
-
22
-
-
18644373047
-
PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
-
Dakic A., Metcalf D., Di Rago L., Mifsud S., Wu L., and Nutt S.L. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J. Exp. Med. 201 (2005) 1487-1502
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1487-1502
-
-
Dakic, A.1
Metcalf, D.2
Di Rago, L.3
Mifsud, S.4
Wu, L.5
Nutt, S.L.6
-
23
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1
-
DeKoter R.P., and Singh H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288 (2000) 1439-1441
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
DeKoter, R.P.1
Singh, H.2
-
24
-
-
0032504051
-
Loops, lineage, and leukemia
-
Enver T., and Greaves M. Loops, lineage, and leukemia. Cell 94 (1998) 9-12
-
(1998)
Cell
, vol.94
, pp. 9-12
-
-
Enver, T.1
Greaves, M.2
-
25
-
-
0027261321
-
Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors
-
Fairbairn L.J., Cowling G.J., Reipert B.M., and Dexter T.M. Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74 (1993) 823-832
-
(1993)
Cell
, vol.74
, pp. 823-832
-
-
Fairbairn, L.J.1
Cowling, G.J.2
Reipert, B.M.3
Dexter, T.M.4
-
26
-
-
0034662159
-
Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages
-
Faust N., Varas F., Kelly L.M., Heck S., and Graf T. Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood 96 (2000) 719-726
-
(2000)
Blood
, vol.96
, pp. 719-726
-
-
Faust, N.1
Varas, F.2
Kelly, L.M.3
Heck, S.4
Graf, T.5
-
27
-
-
0029843938
-
Chromatin structure and gene expression
-
Felsenfeld G., Boyes J., Chung J., Clark D., and Studitsky V. Chromatin structure and gene expression. Proc. Natl. Acad. Sci. USA 93 (1996) 9384-9388
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9384-9388
-
-
Felsenfeld, G.1
Boyes, J.2
Chung, J.3
Clark, D.4
Studitsky, V.5
-
28
-
-
30344444770
-
A clonogenic bone marrow progenitor specific for macrophages and dendritic cells
-
Fogg D.K., Sibon C., Miled C., Jung S., Aucouturier P., Littman D.R., Cumano A., and Geissmann F. A clonogenic bone marrow progenitor specific for macrophages and dendritic cells. Science 311 (2006) 83-87
-
(2006)
Science
, vol.311
, pp. 83-87
-
-
Fogg, D.K.1
Sibon, C.2
Miled, C.3
Jung, S.4
Aucouturier, P.5
Littman, D.R.6
Cumano, A.7
Geissmann, F.8
-
29
-
-
33746208874
-
New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors
-
Forsberg E.C., Serwold T., Kogan S., Weissman I.L., and Passegue E. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell 126 (2006) 415-426
-
(2006)
Cell
, vol.126
, pp. 415-426
-
-
Forsberg, E.C.1
Serwold, T.2
Kogan, S.3
Weissman, I.L.4
Passegue, E.5
-
30
-
-
33747045798
-
Notch/Delta signaling constrains reengineering of pro-T cells by PU.1
-
Franco C.B., Scripture-Adams D.D., Proekt I., Taghon T., Weiss A.H., Yui M.A., Adams S.L., Diamond R.A., and Rothenberg E.V. Notch/Delta signaling constrains reengineering of pro-T cells by PU.1. Proc. Natl. Acad. Sci. USA 103 (2006) 11993-11998
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11993-11998
-
-
Franco, C.B.1
Scripture-Adams, D.D.2
Proekt, I.3
Taghon, T.4
Weiss, A.H.5
Yui, M.A.6
Adams, S.L.7
Diamond, R.A.8
Rothenberg, E.V.9
-
31
-
-
0029926485
-
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1
-
Fujiwara Y., Browne C.P., Cunniff K., Goff S.C., and Orkin S.H. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc. Natl. Acad. Sci. USA 93 (1996) 12355-12358
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12355-12358
-
-
Fujiwara, Y.1
Browne, C.P.2
Cunniff, K.3
Goff, S.C.4
Orkin, S.H.5
-
32
-
-
0942266030
-
Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development
-
Fujiwara Y., Chang A.N., Williams A.M., and Orkin S.H. Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood 103 (2004) 583-585
-
(2004)
Blood
, vol.103
, pp. 583-585
-
-
Fujiwara, Y.1
Chang, A.N.2
Williams, A.M.3
Orkin, S.H.4
-
33
-
-
0033989686
-
Mast cells and basophils
-
Galli S.J. Mast cells and basophils. Curr. Opin. Hematol. 7 (2000) 32-39
-
(2000)
Curr. Opin. Hematol.
, vol.7
, pp. 32-39
-
-
Galli, S.J.1
-
34
-
-
0036566226
-
Differentiation plasticity of hematopoietic cells
-
Graf T. Differentiation plasticity of hematopoietic cells. Blood 99 (2002) 3089-3101
-
(2002)
Blood
, vol.99
, pp. 3089-3101
-
-
Graf, T.1
-
35
-
-
0026723417
-
Chicken "erythroid" cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent
-
Graf T., McNagny K., Brady G., and Frampton J. Chicken "erythroid" cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent. Cell 70 (1992) 201-213
-
(1992)
Cell
, vol.70
, pp. 201-213
-
-
Graf, T.1
McNagny, K.2
Brady, G.3
Frampton, J.4
-
36
-
-
0035171693
-
Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing
-
Gurish M.F., Tao H., Abonia J.P., Arya A., Friend D.S., Parker C.M., and Austen K.F. Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing. J. Exp. Med. 194 (2001) 1243-1252
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1243-1252
-
-
Gurish, M.F.1
Tao, H.2
Abonia, J.P.3
Arya, A.4
Friend, D.S.5
Parker, C.M.6
Austen, K.F.7
-
37
-
-
33745225494
-
C/EBPbeta is required for 'emergency' granulopoiesis
-
Hirai H., Zhang P., Dayaram T., Hetherington C.J., Mizuno S., Imanishi J., Akashi K., and Tenen D.G. C/EBPbeta is required for 'emergency' granulopoiesis. Nat. Immunol. 7 (2006) 732-739
-
(2006)
Nat. Immunol.
, vol.7
, pp. 732-739
-
-
Hirai, H.1
Zhang, P.2
Dayaram, T.3
Hetherington, C.J.4
Mizuno, S.5
Imanishi, J.6
Akashi, K.7
Tenen, D.G.8
-
38
-
-
31444431706
-
Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors
-
Hsu C.L., King-Fleischman A.G., Lai A.Y., Matsumoto Y., Weissman I.L., and Kondo M. Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors. Proc. Natl. Acad. Sci. USA 103 (2006) 672-677
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 672-677
-
-
Hsu, C.L.1
King-Fleischman, A.G.2
Lai, A.Y.3
Matsumoto, Y.4
Weissman, I.L.5
Kondo, M.6
-
39
-
-
0030954167
-
Multilineage gene expression precedes commitment in the hemopoietic system
-
Hu M., Krause D., Greaves M., Sharkis S., Dexter M., Heyworth C., and Enver T. Multilineage gene expression precedes commitment in the hemopoietic system. Genes Dev. 11 (1997) 774-785
-
(1997)
Genes Dev.
, vol.11
, pp. 774-785
-
-
Hu, M.1
Krause, D.2
Greaves, M.3
Sharkis, S.4
Dexter, M.5
Heyworth, C.6
Enver, T.7
-
40
-
-
0036669273
-
Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
-
Igarashi H., Gregory S.C., Yokota T., Sakaguchi N., and Kincade P.W. Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 17 (2002) 117-130
-
(2002)
Immunity
, vol.17
, pp. 117-130
-
-
Igarashi, H.1
Gregory, S.C.2
Yokota, T.3
Sakaguchi, N.4
Kincade, P.W.5
-
41
-
-
0035353180
-
Localization of recombination activating gene 1/green fluorescent protein (RAG1/GFP) expression in secondary lymphoid organs after immunization with T-dependent antigens in rag1/gfp knockin mice
-
Igarashi H., Kuwata N., Kiyota K., Sumita K., Suda T., Ono S., Bauer S.R., and Sakaguchi N. Localization of recombination activating gene 1/green fluorescent protein (RAG1/GFP) expression in secondary lymphoid organs after immunization with T-dependent antigens in rag1/gfp knockin mice. Blood 97 (2001) 2680-2687
-
(2001)
Blood
, vol.97
, pp. 2680-2687
-
-
Igarashi, H.1
Kuwata, N.2
Kiyota, K.3
Sumita, K.4
Suda, T.5
Ono, S.6
Bauer, S.R.7
Sakaguchi, N.8
-
42
-
-
0026500983
-
Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation
-
Ikuta K., and Weissman I.L. Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc. Natl. Acad. Sci. USA 89 (1992) 1502-1506
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 1502-1506
-
-
Ikuta, K.1
Weissman, I.L.2
-
43
-
-
33751071630
-
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages
-
Iwasaki H., Mizuno S., Arinobu Y., Ozawa H., Mori Y., Shigematsu H., Takatsu K., Tenen D.G., and Akashi K. The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev. 20 (2006) 3010-3021
-
(2006)
Genes Dev.
, vol.20
, pp. 3010-3021
-
-
Iwasaki, H.1
Mizuno, S.2
Arinobu, Y.3
Ozawa, H.4
Mori, Y.5
Shigematsu, H.6
Takatsu, K.7
Tenen, D.G.8
Akashi, K.9
-
44
-
-
22344443951
-
Identification of eosinophil lineage-committed progenitors in the murine bone marrow
-
Iwasaki H., Mizuno S., Mayfield R., Shigematsu H., Arinobu Y., Seed B., Gurish M.F., Takatsu K., and Akashi K. Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J. Exp. Med. 201 (2005) 1891-1897
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1891-1897
-
-
Iwasaki, H.1
Mizuno, S.2
Mayfield, R.3
Shigematsu, H.4
Arinobu, Y.5
Seed, B.6
Gurish, M.F.7
Takatsu, K.8
Akashi, K.9
-
45
-
-
0141455931
-
GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages
-
Iwasaki H., Mizuno S., Wells R.A., Cantor A.B., Watanabe S., and Akashi K. GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages. Immunity 19 (2003) 451-462
-
(2003)
Immunity
, vol.19
, pp. 451-462
-
-
Iwasaki, H.1
Mizuno, S.2
Wells, R.A.3
Cantor, A.B.4
Watanabe, S.5
Akashi, K.6
-
46
-
-
23944446085
-
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation
-
Iwasaki H., Somoza C., Shigematsu H., Duprez E.A., Iwasaki-Arai J., Mizuno S., Arinobu Y., Geary K., Zhang P., Dayaram T., et al. Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood 106 (2005) 1590-1600
-
(2005)
Blood
, vol.106
, pp. 1590-1600
-
-
Iwasaki, H.1
Somoza, C.2
Shigematsu, H.3
Duprez, E.A.4
Iwasaki-Arai, J.5
Mizuno, S.6
Arinobu, Y.7
Geary, K.8
Zhang, P.9
Dayaram, T.10
-
47
-
-
0037515610
-
Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion
-
Iwasaki-Arai J., Iwasaki H., Miyamoto T., Watanabe S., and Akashi K. Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion. J. Exp. Med. 197 (2003) 1311-1322
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1311-1322
-
-
Iwasaki-Arai, J.1
Iwasaki, H.2
Miyamoto, T.3
Watanabe, S.4
Akashi, K.5
-
48
-
-
0037085568
-
Expression of C/EBPbeta from the C/ebpalpha gene locus is sufficient for normal hematopoiesis in vivo
-
Jones L.C., Lin M.L., Chen S.S., Krug U., Hofmann W.K., Lee S., Lee Y.H., and Koeffler H.P. Expression of C/EBPbeta from the C/ebpalpha gene locus is sufficient for normal hematopoiesis in vivo. Blood 99 (2002) 2032-2036
-
(2002)
Blood
, vol.99
, pp. 2032-2036
-
-
Jones, L.C.1
Lin, M.L.2
Chen, S.S.3
Krug, U.4
Hofmann, W.K.5
Lee, S.6
Lee, Y.H.7
Koeffler, H.P.8
-
49
-
-
0042662868
-
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo
-
Karsunky H., Merad M., Cozzio A., Weissman I.L., and Manz M.G. Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J. Exp. Med. 198 (2003) 305-313
-
(2003)
J. Exp. Med.
, vol.198
, pp. 305-313
-
-
Karsunky, H.1
Merad, M.2
Cozzio, A.3
Weissman, I.L.4
Manz, M.G.5
-
50
-
-
0037544006
-
A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis
-
Kaufmann C., Yoshida T., Perotti E.A., Landhuis E., Wu P., and Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. EMBO J. 22 (2003) 2211-2223
-
(2003)
EMBO J.
, vol.22
, pp. 2211-2223
-
-
Kaufmann, C.1
Yoshida, T.2
Perotti, E.A.3
Landhuis, E.4
Wu, P.5
Georgopoulos, K.6
-
51
-
-
0037007023
-
Lineage infidelity in myeloid cells with TCR gene rearrangement: A latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling
-
King A.G., Kondo M., Scherer D.C., and Weissman I.L. Lineage infidelity in myeloid cells with TCR gene rearrangement: A latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling. Proc. Natl. Acad. Sci. USA 99 (2002) 4508-4513
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4508-4513
-
-
King, A.G.1
Kondo, M.2
Scherer, D.C.3
Weissman, I.L.4
-
52
-
-
0034699390
-
Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines
-
Kondo M., Scherer D.C., Miyamoto T., King A.G., Akashi K., Sugamura K., and Weissman I.L. Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines. Nature 407 (2000) 383-386
-
(2000)
Nature
, vol.407
, pp. 383-386
-
-
Kondo, M.1
Scherer, D.C.2
Miyamoto, T.3
King, A.G.4
Akashi, K.5
Sugamura, K.6
Weissman, I.L.7
-
53
-
-
0028327550
-
Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes
-
Kondo M., Takeshita T., Higuchi M., Nakamura M., Sudo T., Nishikawa S., and Sugamura K. Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes. Science 263 (1994) 1453-1454
-
(1994)
Science
, vol.263
, pp. 1453-1454
-
-
Kondo, M.1
Takeshita, T.2
Higuchi, M.3
Nakamura, M.4
Sudo, T.5
Nishikawa, S.6
Sugamura, K.7
-
54
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo M., Weissman I.L., and Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91 (1997) 661-672
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
55
-
-
0034663810
-
Chromatin fine structure profiles for a developmentally regulated gene: Reorganization of the lysozyme locus before trans-activator binding and gene expression
-
Kontaraki J., Chen H.H., Riggs A., and Bonifer C. Chromatin fine structure profiles for a developmentally regulated gene: Reorganization of the lysozyme locus before trans-activator binding and gene expression. Genes Dev. 14 (2000) 2106-2122
-
(2000)
Genes Dev.
, vol.14
, pp. 2106-2122
-
-
Kontaraki, J.1
Chen, H.H.2
Riggs, A.3
Bonifer, C.4
-
56
-
-
0029066359
-
GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts
-
Kulessa H., Frampton J., and Graf T. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes Dev. 9 (1995) 1250-1262
-
(1995)
Genes Dev.
, vol.9
, pp. 1250-1262
-
-
Kulessa, H.1
Frampton, J.2
Graf, T.3
-
57
-
-
0032740593
-
Cutting edge: Absence of expression of RAG1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene
-
Kuwata N., Igarashi H., Ohmura T., Aizawa S., and Sakaguchi N. Cutting edge: Absence of expression of RAG1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene. J. Immunol. 163 (1999) 6355-6359
-
(1999)
J. Immunol.
, vol.163
, pp. 6355-6359
-
-
Kuwata, N.1
Igarashi, H.2
Ohmura, T.3
Aizawa, S.4
Sakaguchi, N.5
-
58
-
-
33746906644
-
Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors
-
Lai A.Y., and Kondo M. Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. J. Exp. Med. 203 (2006) 1867-1873
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1867-1873
-
-
Lai, A.Y.1
Kondo, M.2
-
59
-
-
33644641356
-
Determinants of lymphoid-myeloid lineage diversification
-
Laiosa C.V., Stadtfeld M., and Graf T. Determinants of lymphoid-myeloid lineage diversification. Annu. Rev. Immunol. 24 (2006) 705-738
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 705-738
-
-
Laiosa, C.V.1
Stadtfeld, M.2
Graf, T.3
-
60
-
-
33846257739
-
Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors
-
Laiosa C.V., Stadtfeld M., Xie H., de Andres-Aguayo L., and Graf T. Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors. Immunity 25 (2006) 731-744
-
(2006)
Immunity
, vol.25
, pp. 731-744
-
-
Laiosa, C.V.1
Stadtfeld, M.2
Xie, H.3
de Andres-Aguayo, L.4
Graf, T.5
-
61
-
-
33747196725
-
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
-
Laslo P., Spooner C.J., Warmflash A., Lancki D.W., Lee H.J., Sciammas R., Gantner B.N., Dinner A.R., and Singh H. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 126 (2006) 755-766
-
(2006)
Cell
, vol.126
, pp. 755-766
-
-
Laslo, P.1
Spooner, C.J.2
Warmflash, A.3
Lancki, D.W.4
Lee, H.J.5
Sciammas, R.6
Gantner, B.N.7
Dinner, A.R.8
Singh, H.9
-
62
-
-
0028907847
-
Murine hematopoietic stem and progenitor cells: I. Enrichment and biologic characterization
-
Li C.L., and Johnson G.R. Murine hematopoietic stem and progenitor cells: I. Enrichment and biologic characterization. Blood 85 (1995) 1472-1479
-
(1995)
Blood
, vol.85
, pp. 1472-1479
-
-
Li, C.L.1
Johnson, G.R.2
-
63
-
-
0029097145
-
Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors
-
Mackarehtschian K., Hardin J.D., Moore K.A., Boast S., Goff S.P., and Lemischka I.R. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 3 (1995) 147-161
-
(1995)
Immunity
, vol.3
, pp. 147-161
-
-
Mackarehtschian, K.1
Hardin, J.D.2
Moore, K.A.3
Boast, S.4
Goff, S.P.5
Lemischka, I.R.6
-
64
-
-
34247092922
-
Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
-
Mansson R., Hultquist A., Luc S., Yang L., Anderson K., Kharazi S., Al-Hashmi S., Liuba K., Thoren L., Adolfsson J., et al. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26 (2007) 407-419
-
(2007)
Immunity
, vol.26
, pp. 407-419
-
-
Mansson, R.1
Hultquist, A.2
Luc, S.3
Yang, L.4
Anderson, K.5
Kharazi, S.6
Al-Hashmi, S.7
Liuba, K.8
Thoren, L.9
Adolfsson, J.10
-
65
-
-
0035383775
-
Dendritic cell potentials of early lymphoid and myeloid progenitors
-
Manz M.G., Traver D., Miyamoto T., Weissman I.L., and Akashi K. Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 97 (2001) 3333-3341
-
(2001)
Blood
, vol.97
, pp. 3333-3341
-
-
Manz, M.G.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
Akashi, K.5
-
67
-
-
0034210658
-
Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells
-
McKenna H.J., Stocking K.L., Miller R.E., Brasel K., De Smedt T., Maraskovsky E., Maliszewski C.R., Lynch D.H., Smith J., Pulendran B., et al. Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells. Blood 95 (2000) 3489-3497
-
(2000)
Blood
, vol.95
, pp. 3489-3497
-
-
McKenna, H.J.1
Stocking, K.L.2
Miller, R.E.3
Brasel, K.4
De Smedt, T.5
Maraskovsky, E.6
Maliszewski, C.R.7
Lynch, D.H.8
Smith, J.9
Pulendran, B.10
-
68
-
-
0242549003
-
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
-
McKercher S.R., Torbett B.E., Anderson K.L., Henkel G.W., Vestal D.J., Baribault H., Klemsz M., Feeney A.J., Wu G.E., Paige C.J., and Maki R.A. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J. 15 (1996) 5647-5658
-
(1996)
EMBO J.
, vol.15
, pp. 5647-5658
-
-
McKercher, S.R.1
Torbett, B.E.2
Anderson, K.L.3
Henkel, G.W.4
Vestal, D.J.5
Baribault, H.6
Klemsz, M.7
Feeney, A.J.8
Wu, G.E.9
Paige, C.J.10
Maki, R.A.11
-
69
-
-
0032528354
-
Lineage commitment and maturation in hematopoietic cells: The case for extrinsic regulation
-
Metcalf D. Lineage commitment and maturation in hematopoietic cells: The case for extrinsic regulation. Blood 92 (1998) 345-347
-
(1998)
Blood
, vol.92
, pp. 345-347
-
-
Metcalf, D.1
-
70
-
-
0036070180
-
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment
-
Miyamoto T., Iwasaki H., Reizis B., Ye M., Graf T., Weissman I.L., and Akashi K. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev. Cell 3 (2002) 137-147
-
(2002)
Dev. Cell
, vol.3
, pp. 137-147
-
-
Miyamoto, T.1
Iwasaki, H.2
Reizis, B.3
Ye, M.4
Graf, T.5
Weissman, I.L.6
Akashi, K.7
-
71
-
-
0032212250
-
The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors
-
Moritz D.R., Rodewald H.R., Gheyselinck J., and Klemenz R. The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors. J. Immunol. 161 (1998) 4866-4874
-
(1998)
J. Immunol.
, vol.161
, pp. 4866-4874
-
-
Moritz, D.R.1
Rodewald, H.R.2
Gheyselinck, J.3
Klemenz, R.4
-
72
-
-
0030987304
-
Identification of a lineage of multipotent hematopoietic progenitors
-
Morrison S.J., Wandycz A.M., Hemmati H.D., Wright D.E., and Weissman I.L. Identification of a lineage of multipotent hematopoietic progenitors. Development 124 (1997) 1929-1939
-
(1997)
Development
, vol.124
, pp. 1929-1939
-
-
Morrison, S.J.1
Wandycz, A.M.2
Hemmati, H.D.3
Wright, D.E.4
Weissman, I.L.5
-
73
-
-
0028534860
-
The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
-
Morrison S.J., and Weissman I.L. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1 (1994) 661-673
-
(1994)
Immunity
, vol.1
, pp. 661-673
-
-
Morrison, S.J.1
Weissman, I.L.2
-
74
-
-
0035313834
-
Chromatin remodeling in development and differentiation
-
Muller C., and Leutz A. Chromatin remodeling in development and differentiation. Curr Opin Genet Dev. 11 (2001) 167-174
-
(2001)
Curr Opin Genet Dev.
, vol.11
, pp. 167-174
-
-
Muller, C.1
Leutz, A.2
-
75
-
-
0036081059
-
Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S
-
Na Nakorn T., Traver D., Weissman I.L., and Akashi K. Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J. Clin. Invest. 109 (2002) 1579-1585
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1579-1585
-
-
Na Nakorn, T.1
Traver, D.2
Weissman, I.L.3
Akashi, K.4
-
76
-
-
0030451722
-
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
-
Nakao M., Yokota S., Iwai T., Kaneko H., Horiike S., Kashima K., Sonoda Y., Fujimoto T., and Misawa S. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia 10 (1996) 1911-1918
-
(1996)
Leukemia
, vol.10
, pp. 1911-1918
-
-
Nakao, M.1
Yokota, S.2
Iwai, T.3
Kaneko, H.4
Horiike, S.5
Kashima, K.6
Sonoda, Y.7
Fujimoto, T.8
Misawa, S.9
-
78
-
-
0032146794
-
PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors
-
Nerlov C., and Graf T. PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev. 12 (1998) 2403-2412
-
(1998)
Genes Dev.
, vol.12
, pp. 2403-2412
-
-
Nerlov, C.1
Graf, T.2
-
79
-
-
0034656393
-
GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription
-
Nerlov C., Querfurth E., Kulessa H., and Graf T. GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription. Blood 95 (2000) 2543-2551
-
(2000)
Blood
, vol.95
, pp. 2543-2551
-
-
Nerlov, C.1
Querfurth, E.2
Kulessa, H.3
Graf, T.4
-
80
-
-
0033231420
-
Defects in hemopoietic stem cell activity in Ikaros mutant mice
-
Nichogiannopoulou A., Trevisan M., Neben S., Friedrich C., and Georgopoulos K. Defects in hemopoietic stem cell activity in Ikaros mutant mice. J. Exp. Med. 190 (1999) 1201-1214
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1201-1214
-
-
Nichogiannopoulou, A.1
Trevisan, M.2
Neben, S.3
Friedrich, C.4
Georgopoulos, K.5
-
81
-
-
0027751556
-
Interleukin-2 receptor gamma chain: A functional component of the interleukin-7 receptor
-
Noguchi M., Nakamura Y., Russell S.M., Ziegler S.F., Tsang M., Cao X., and Leonard W.J. Interleukin-2 receptor gamma chain: A functional component of the interleukin-7 receptor. Science 262 (1993) 1877-1880
-
(1993)
Science
, vol.262
, pp. 1877-1880
-
-
Noguchi, M.1
Nakamura, Y.2
Russell, S.M.3
Ziegler, S.F.4
Tsang, M.5
Cao, X.6
Leonard, W.J.7
-
82
-
-
13244277736
-
Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors
-
Nutt S.L., Metcalf D., D'Amico A., Polli M., and Wu L. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J. Exp. Med. 201 (2005) 221-231
-
(2005)
J. Exp. Med.
, vol.201
, pp. 221-231
-
-
Nutt, S.L.1
Metcalf, D.2
D'Amico, A.3
Polli, M.4
Wu, L.5
-
83
-
-
0032599946
-
Stochastic model revisited
-
Ogawa M. Stochastic model revisited. Int. J. Hematol. 69 (1999) 2-5
-
(1999)
Int. J. Hematol.
, vol.69
, pp. 2-5
-
-
Ogawa, M.1
-
84
-
-
20144368117
-
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element
-
Okuno Y., Huang G., Rosenbauer F., Evans E.K., Radomska H.S., Iwasaki H., Akashi K., Moreau-Gachelin F., Li Y., Zhang P., et al. Potential autoregulation of transcription factor PU.1 by an upstream regulatory element. Mol Cell Biol. 25 (2005) 2832-2845
-
(2005)
Mol Cell Biol.
, vol.25
, pp. 2832-2845
-
-
Okuno, Y.1
Huang, G.2
Rosenbauer, F.3
Evans, E.K.4
Radomska, H.S.5
Iwasaki, H.6
Akashi, K.7
Moreau-Gachelin, F.8
Li, Y.9
Zhang, P.10
-
85
-
-
0034303586
-
Diversification of haematopoietic stem cells to specific lineages
-
Orkin S.H. Diversification of haematopoietic stem cells to specific lineages. Nat. Rev. Genet. 1 (2000) 57-64
-
(2000)
Nat. Rev. Genet.
, vol.1
, pp. 57-64
-
-
Orkin, S.H.1
-
86
-
-
0029796633
-
Long-term lymphohematopoietic reconstitution by a single CD34- low/negative hematopoietic stem cell
-
Osawa M., Hanada K., Hamada H., and Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34- low/negative hematopoietic stem cell. Science 273 (1996) 242-245
-
(1996)
Science
, vol.273
, pp. 242-245
-
-
Osawa, M.1
Hanada, K.2
Hamada, H.3
Nakauchi, H.4
-
87
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
-
Peschon J.J., Morrissey P.J., Grabstein K.H., Ramsdell F.J., Maraskovsky E., Gliniak B.C., Park L.S., Ziegler S.F., Williams D.E., Ware C.B., et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180 (1994) 1955-1960
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1955-1960
-
-
Peschon, J.J.1
Morrissey, P.J.2
Grabstein, K.H.3
Ramsdell, F.J.4
Maraskovsky, E.5
Gliniak, B.C.6
Park, L.S.7
Ziegler, S.F.8
Williams, D.E.9
Ware, C.B.10
-
88
-
-
0030007289
-
Expression of murine CD38 defines a population of long-term reconstituting hematopoietic stem cells
-
Randall T.D., Lund F.E., Howard M.C., and Weissman I.L. Expression of murine CD38 defines a population of long-term reconstituting hematopoietic stem cells. Blood 87 (1996) 4057-4067
-
(1996)
Blood
, vol.87
, pp. 4057-4067
-
-
Randall, T.D.1
Lund, F.E.2
Howard, M.C.3
Weissman, I.L.4
-
89
-
-
0037100304
-
Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: Possible role in lineage commitment decisions
-
Reddy V.A., Iwama A., Iotzova G., Schulz M., Elsasser A., Vangala R.K., Tenen D.G., Hiddemann W., and Behre G. Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: Possible role in lineage commitment decisions. Blood 100 (2002) 483-490
-
(2002)
Blood
, vol.100
, pp. 483-490
-
-
Reddy, V.A.1
Iwama, A.2
Iotzova, G.3
Schulz, M.4
Elsasser, A.5
Vangala, R.K.6
Tenen, D.G.7
Hiddemann, W.8
Behre, G.9
-
90
-
-
0033577844
-
Expression of the mouse pre-T cell receptor alpha gene is controlled by an upstream region containing a transcriptional enhancer
-
Reizis B., and Leder P. Expression of the mouse pre-T cell receptor alpha gene is controlled by an upstream region containing a transcriptional enhancer. J. Exp. Med. 189 (1999) 1669-1678
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1669-1678
-
-
Reizis, B.1
Leder, P.2
-
91
-
-
0033151624
-
Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: Functional antagonism in erythroid cells
-
Rekhtman N., Radparvar F., Evans T., and Skoultchi A.I. Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: Functional antagonism in erythroid cells. Genes Dev. 13 (1999) 1398-1411
-
(1999)
Genes Dev.
, vol.13
, pp. 1398-1411
-
-
Rekhtman, N.1
Radparvar, F.2
Evans, T.3
Skoultchi, A.I.4
-
92
-
-
33846622099
-
Transcription factors in myeloid development: Balancing differentiation with transformation
-
Rosenbauer F., and Tenen D.G. Transcription factors in myeloid development: Balancing differentiation with transformation. Nat. Rev. Immunol. 7 (2007) 105-117
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 105-117
-
-
Rosenbauer, F.1
Tenen, D.G.2
-
94
-
-
34250203551
-
Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals
-
this issue
-
Rothenberg E.V. Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals. Immunity 26 (2007) 690-702 this issue
-
(2007)
Immunity
, vol.26
, pp. 690-702
-
-
Rothenberg, E.V.1
-
95
-
-
0036916440
-
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
-
Schmitt T.M., and Zuniga-Pflucker J.C. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 17 (2002) 749-756
-
(2002)
Immunity
, vol.17
, pp. 749-756
-
-
Schmitt, T.M.1
Zuniga-Pflucker, J.C.2
-
96
-
-
0028136726
-
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
-
Scott E.W., Simon M.C., Anastasi J., and Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265 (1994) 1573-1577
-
(1994)
Science
, vol.265
, pp. 1573-1577
-
-
Scott, E.W.1
Simon, M.C.2
Anastasi, J.3
Singh, H.4
-
97
-
-
3142749595
-
Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin
-
Shigematsu H., Reizis B., Iwasaki H., Mizuno S., Hu D., Traver D., Leder P., Sakaguchi N., and Akashi K. Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin. Immunity 21 (2004) 43-53
-
(2004)
Immunity
, vol.21
, pp. 43-53
-
-
Shigematsu, H.1
Reizis, B.2
Iwasaki, H.3
Mizuno, S.4
Hu, D.5
Traver, D.6
Leder, P.7
Sakaguchi, N.8
Akashi, K.9
-
98
-
-
0030926006
-
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
-
Shivdasani R.A., Fujiwara Y., McDevitt M.A., and Orkin S.H. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 16 (1997) 3965-3973
-
(1997)
EMBO J.
, vol.16
, pp. 3965-3973
-
-
Shivdasani, R.A.1
Fujiwara, Y.2
McDevitt, M.A.3
Orkin, S.H.4
-
99
-
-
33644643428
-
Gene regulatory networks and the determination of lymphoid cell fates
-
Singh H., and Pongubala J.M. Gene regulatory networks and the determination of lymphoid cell fates. Curr. Opin. Immunol. 18 (2006) 116-120
-
(2006)
Curr. Opin. Immunol.
, vol.18
, pp. 116-120
-
-
Singh, H.1
Pongubala, J.M.2
-
100
-
-
0036797682
-
Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool
-
Sitnicka E., Bryder D., Theilgaard-Monch K., Buza-Vidas N., Adolfsson J., and Jacobsen S.E. Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool. Immunity 17 (2002) 463-472
-
(2002)
Immunity
, vol.17
, pp. 463-472
-
-
Sitnicka, E.1
Bryder, D.2
Theilgaard-Monch, K.3
Buza-Vidas, N.4
Adolfsson, J.5
Jacobsen, S.E.6
-
102
-
-
0023922373
-
Purification and characterization of mouse hematopoietic stem cells
-
Spangrude G.J., Heimfeld S., and Weissman I.L. Purification and characterization of mouse hematopoietic stem cells. Science 241 (1988) 58-62
-
(1988)
Science
, vol.241
, pp. 58-62
-
-
Spangrude, G.J.1
Heimfeld, S.2
Weissman, I.L.3
-
103
-
-
0141465061
-
The role of FLT3 in haematopoietic malignancies
-
Stirewalt D.L., and Radich J.P. The role of FLT3 in haematopoietic malignancies. Nat. Rev. Cancer 3 (2003) 650-665
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 650-665
-
-
Stirewalt, D.L.1
Radich, J.P.2
-
104
-
-
0343099332
-
Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations
-
Suda T., Suda J., and Ogawa M. Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations. Proc. Natl. Acad. Sci. USA 80 (1983) 6689-6693
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6689-6693
-
-
Suda, T.1
Suda, J.2
Ogawa, M.3
-
105
-
-
0034254262
-
GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies
-
Takahashi S., Shimizu R., Suwabe N., Kuroha T., Yoh K., Ohta J., Nishimura S., Lim K.C., Engel J.D., and Yamamoto M. GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies. Blood 96 (2000) 910-916
-
(2000)
Blood
, vol.96
, pp. 910-916
-
-
Takahashi, S.1
Shimizu, R.2
Suwabe, N.3
Kuroha, T.4
Yoh, K.5
Ohta, J.6
Nishimura, S.7
Lim, K.C.8
Engel, J.D.9
Yamamoto, M.10
-
106
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen D.G. Disruption of differentiation in human cancer: AML shows the way. Nat. Rev. Cancer 3 (2003) 89-101
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
107
-
-
2442641790
-
Lineage commitment and developmental plasticity in early lymphoid progenitor subsets
-
Traver D., and Akashi K. Lineage commitment and developmental plasticity in early lymphoid progenitor subsets. Adv. Immunol. 83 (2004) 1-54
-
(2004)
Adv. Immunol.
, vol.83
, pp. 1-54
-
-
Traver, D.1
Akashi, K.2
-
108
-
-
0034670385
-
Development of CD8alpha-positive dendritic cells from a common myeloid progenitor
-
Traver D., Akashi K., Manz M., Merad M., Miyamoto T., Engleman E.G., and Weissman I.L. Development of CD8alpha-positive dendritic cells from a common myeloid progenitor. Science 290 (2000) 2152-2154
-
(2000)
Science
, vol.290
, pp. 2152-2154
-
-
Traver, D.1
Akashi, K.2
Manz, M.3
Merad, M.4
Miyamoto, T.5
Engleman, E.G.6
Weissman, I.L.7
-
109
-
-
0030926190
-
Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation
-
Tsai F.Y., and Orkin S.H. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 89 (1997) 3636-3643
-
(1997)
Blood
, vol.89
, pp. 3636-3643
-
-
Tsai, F.Y.1
Orkin, S.H.2
-
110
-
-
0025876999
-
Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter
-
Tsai S.F., Strauss E., and Orkin S.H. Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter. Genes Dev. 5 (1991) 919-931
-
(1991)
Genes Dev.
, vol.5
, pp. 919-931
-
-
Tsai, S.F.1
Strauss, E.2
Orkin, S.H.3
-
111
-
-
0032522474
-
Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
-
Tsang A.P., Fujiwara Y., Hom D.B., and Orkin S.H. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes Dev. 12 (1998) 1176-1188
-
(1998)
Genes Dev.
, vol.12
, pp. 1176-1188
-
-
Tsang, A.P.1
Fujiwara, Y.2
Hom, D.B.3
Orkin, S.H.4
-
112
-
-
0028929565
-
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
-
von Freeden-Jeffry U., Vieira P., Lucian L.A., McNeil T., Burdach S.E., and Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181 (1995) 1519-1526
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1519-1526
-
-
von Freeden-Jeffry, U.1
Vieira, P.2
Lucian, L.A.3
McNeil, T.4
Burdach, S.E.5
Murray, R.6
-
113
-
-
0030498975
-
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
-
Wang J.H., Nichogiannopoulou A., Wu L., Sun L., Sharpe A.H., Bigby M., and Georgopoulos K. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5 (1996) 537-549
-
(1996)
Immunity
, vol.5
, pp. 537-549
-
-
Wang, J.H.1
Nichogiannopoulou, A.2
Wu, L.3
Sun, L.4
Sharpe, A.H.5
Bigby, M.6
Georgopoulos, K.7
-
114
-
-
0037375763
-
Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors
-
Warren L.A., and Rothenberg E.V. Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors. Curr. Opin. Immunol. 15 (2003) 166-175
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 166-175
-
-
Warren, L.A.1
Rothenberg, E.V.2
-
115
-
-
0033729622
-
Roles of mast cells and basophils in innate and acquired immunity
-
Wedemeyer J., Tsai M., and Galli S.J. Roles of mast cells and basophils in innate and acquired immunity. Curr. Opin. Immunol. 12 (2000) 624-631
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 624-631
-
-
Wedemeyer, J.1
Tsai, M.2
Galli, S.J.3
-
116
-
-
0022137507
-
Assembly and propagation of repressed and depressed chromosomal states
-
Weintraub H. Assembly and propagation of repressed and depressed chromosomal states. Cell 42 (1985) 705-711
-
(1985)
Cell
, vol.42
, pp. 705-711
-
-
Weintraub, H.1
-
117
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages
-
Xie H., Ye M., Feng R., and Graf T. Stepwise reprogramming of B cells into macrophages. Cell 117 (2004) 663-676
-
(2004)
Cell
, vol.117
, pp. 663-676
-
-
Xie, H.1
Ye, M.2
Feng, R.3
Graf, T.4
-
118
-
-
0344276481
-
Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential
-
Ye M., Iwasaki H., Laiosa C.V., Stadtfeld M., Xie H., Heck S., Clausen B., Akashi K., and Graf T. Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential. Immunity 19 (2003) 689-699
-
(2003)
Immunity
, vol.19
, pp. 689-699
-
-
Ye, M.1
Iwasaki, H.2
Laiosa, C.V.3
Stadtfeld, M.4
Xie, H.5
Heck, S.6
Clausen, B.7
Akashi, K.8
Graf, T.9
-
120
-
-
0037013924
-
Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo
-
Yu C., Cantor A.B., Yang H., Browne C., Wells R.A., Fujiwara Y., and Orkin S.H. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J. Exp. Med. 195 (2002) 1387-1395
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1387-1395
-
-
Yu, C.1
Cantor, A.B.2
Yang, H.3
Browne, C.4
Wells, R.A.5
Fujiwara, Y.6
Orkin, S.H.7
-
121
-
-
0031029557
-
Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha- deficient mice
-
Zhang D.E., Zhang P., Wang N.D., Hetherington C.J., Darlington G.J., and Tenen D.G. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha- deficient mice. Proc. Natl. Acad. Sci. USA 94 (1997) 569-574
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 569-574
-
-
Zhang, D.E.1
Zhang, P.2
Wang, N.D.3
Hetherington, C.J.4
Darlington, G.J.5
Tenen, D.G.6
-
122
-
-
0033587755
-
Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1
-
Zhang P., Behre G., Pan J., Iwama A., Wara-Aswapati N., Radomska H.S., Auron P.E., Tenen D.G., and Sun Z. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proc. Natl. Acad. Sci. USA 96 (1999) 8705-8710
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8705-8710
-
-
Zhang, P.1
Behre, G.2
Pan, J.3
Iwama, A.4
Wara-Aswapati, N.5
Radomska, H.S.6
Auron, P.E.7
Tenen, D.G.8
Sun, Z.9
-
123
-
-
10344230611
-
Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha
-
Zhang P., Iwasaki-Arai J., Iwasaki H., Fenyus M.L., Dayaram T., Owens B.M., Shigematsu H., Levantini E., Huettner C.S., Lekstrom-Himes J.A., et al. Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. Immunity 21 (2004) 853-863
-
(2004)
Immunity
, vol.21
, pp. 853-863
-
-
Zhang, P.1
Iwasaki-Arai, J.2
Iwasaki, H.3
Fenyus, M.L.4
Dayaram, T.5
Owens, B.M.6
Shigematsu, H.7
Levantini, E.8
Huettner, C.S.9
Lekstrom-Himes, J.A.10
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