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Volumn 26, Issue 6, 2007, Pages 726-740

Myeloid Lineage Commitment from the Hematopoietic Stem Cell

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 1; CD11B ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD4 ANTIGEN; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR PU 1; VASCULAR CELL ADHESION MOLECULE 1;

EID: 34250214880     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2007.06.004     Document Type: Review
Times cited : (302)

References (123)
  • 1
    • 0034749999 scopus 로고    scopus 로고
    • Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity
    • Adolfsson J., Borge O.J., Bryder D., Theilgaard-Monch K., Astrand-Grundstrom I., Sitnicka E., Sasaki Y., and Jacobsen S.E. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity 15 (2001) 659-669
    • (2001) Immunity , vol.15 , pp. 659-669
    • Adolfsson, J.1    Borge, O.J.2    Bryder, D.3    Theilgaard-Monch, K.4    Astrand-Grundstrom, I.5    Sitnicka, E.6    Sasaki, Y.7    Jacobsen, S.E.8
  • 2
    • 20244387299 scopus 로고    scopus 로고
    • Identification of flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
    • Adolfsson J., Mansson R., Buza-Vidas N., Hultquist A., Liuba K., Jensen C.T., Bryder D., Yang L., Borge O.J., Thoren L.A., et al. Identification of flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121 (2005) 295-306
    • (2005) Cell , vol.121 , pp. 295-306
    • Adolfsson, J.1    Mansson, R.2    Buza-Vidas, N.3    Hultquist, A.4    Liuba, K.5    Jensen, C.T.6    Bryder, D.7    Yang, L.8    Borge, O.J.9    Thoren, L.A.10
  • 3
    • 0037438387 scopus 로고    scopus 로고
    • Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis
    • Akashi K., He X., Chen J., Iwasaki H., Niu C., Steenhard B., Zhang J., Haug J., and Li L. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 101 (2003) 383-389
    • (2003) Blood , vol.101 , pp. 383-389
    • Akashi, K.1    He, X.2    Chen, J.3    Iwasaki, H.4    Niu, C.5    Steenhard, B.6    Zhang, J.7    Haug, J.8    Li, L.9
  • 4
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi K., Kondo M., von Freeden-Jeffry U., Murray R., and Weissman I.L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89 (1997) 1033-1041
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 5
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K., Traver D., Miyamoto T., and Weissman I.L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404 (2000) 193-197
    • (2000) Nature , vol.404 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 6
    • 17444408151 scopus 로고    scopus 로고
    • The complex cartography of stem cell commitment
    • Akashi K., Traver D., and Zon L.I. The complex cartography of stem cell commitment. Cell 121 (2005) 160-162
    • (2005) Cell , vol.121 , pp. 160-162
    • Akashi, K.1    Traver, D.2    Zon, L.I.3
  • 7
    • 1242274449 scopus 로고    scopus 로고
    • Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems
    • Angeli D., Ferrell Jr. J.E., and Sontag E.D. Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Proc. Natl. Acad. Sci. USA 101 (2004) 1822-1827
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1822-1827
    • Angeli, D.1    Ferrell Jr., J.E.2    Sontag, E.D.3
  • 9
    • 2342488710 scopus 로고    scopus 로고
    • PU.1 determines the self-renewal capacity of erythroid progenitor cells
    • Back J., Dierich A., Bronn C., Kastner P., and Chan S. PU.1 determines the self-renewal capacity of erythroid progenitor cells. Blood 103 (2004) 3615-3623
    • (2004) Blood , vol.103 , pp. 3615-3623
    • Back, J.1    Dierich, A.2    Bronn, C.3    Kastner, P.4    Chan, S.5
  • 10
    • 0034840431 scopus 로고    scopus 로고
    • Chromatin goes global
    • Berger S.L., and Felsenfeld G. Chromatin goes global. Mol. Cell 8 (2001) 263-268
    • (2001) Mol. Cell , vol.8 , pp. 263-268
    • Berger, S.L.1    Felsenfeld, G.2
  • 12
    • 25444433301 scopus 로고    scopus 로고
    • Epigenetic plasticity of hematopoietic cells
    • Bonifer C. Epigenetic plasticity of hematopoietic cells. Cell Cycle 4 (2005) 211-214
    • (2005) Cell Cycle , vol.4 , pp. 211-214
    • Bonifer, C.1
  • 13
    • 0033485342 scopus 로고    scopus 로고
    • Lymphoid-restricted development from multipotent candidate murine stem cells: Distinct and complimentary functions of the c-kit and flt3-ligands
    • Borge O.J., Adolfsson J., and Jacobsen A.M. Lymphoid-restricted development from multipotent candidate murine stem cells: Distinct and complimentary functions of the c-kit and flt3-ligands. Blood 94 (1999) 3781-3790
    • (1999) Blood , vol.94 , pp. 3781-3790
    • Borge, O.J.1    Adolfsson, J.2    Jacobsen, A.M.3
  • 17
    • 0035807964 scopus 로고    scopus 로고
    • Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
    • Christensen J.L., and Weissman I.L. Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells. Proc. Natl. Acad. Sci. USA 98 (2001) 14541-14546
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14541-14546
    • Christensen, J.L.1    Weissman, I.L.2
  • 18
    • 0035353208 scopus 로고    scopus 로고
    • Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells
    • Colucci F., Samson S.I., DeKoter R.P., Lantz O., Singh H., and Di Santo J.P. Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells. Blood 97 (2001) 2625-2632
    • (2001) Blood , vol.97 , pp. 2625-2632
    • Colucci, F.1    Samson, S.I.2    DeKoter, R.P.3    Lantz, O.4    Singh, H.5    Di Santo, J.P.6
  • 19
    • 0032567938 scopus 로고    scopus 로고
    • Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor
    • Corcoran A.E., Riddell A., Krooshoop D., and Venkitaraman A.R. Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor. Nature 391 (1998) 904-907
    • (1998) Nature , vol.391 , pp. 904-907
    • Corcoran, A.E.1    Riddell, A.2    Krooshoop, D.3    Venkitaraman, A.R.4
  • 20
    • 0030838280 scopus 로고    scopus 로고
    • The lineage commitment of haemopoietic progenitor cells
    • Cross M.A., and Enver T. The lineage commitment of haemopoietic progenitor cells. Curr. Opin. Genet. Dev. 7 (1997) 609-613
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 609-613
    • Cross, M.A.1    Enver, T.2
  • 21
    • 0142124320 scopus 로고    scopus 로고
    • Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor
    • Dahl R., Walsh J.C., Lancki D., Laslo P., Iyer S.R., Singh H., and Simon M.C. Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat. Immunol. 4 (2003) 1029-1036
    • (2003) Nat. Immunol. , vol.4 , pp. 1029-1036
    • Dahl, R.1    Walsh, J.C.2    Lancki, D.3    Laslo, P.4    Iyer, S.R.5    Singh, H.6    Simon, M.C.7
  • 22
    • 18644373047 scopus 로고    scopus 로고
    • PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
    • Dakic A., Metcalf D., Di Rago L., Mifsud S., Wu L., and Nutt S.L. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J. Exp. Med. 201 (2005) 1487-1502
    • (2005) J. Exp. Med. , vol.201 , pp. 1487-1502
    • Dakic, A.1    Metcalf, D.2    Di Rago, L.3    Mifsud, S.4    Wu, L.5    Nutt, S.L.6
  • 23
    • 0034717335 scopus 로고    scopus 로고
    • Regulation of B lymphocyte and macrophage development by graded expression of PU.1
    • DeKoter R.P., and Singh H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288 (2000) 1439-1441
    • (2000) Science , vol.288 , pp. 1439-1441
    • DeKoter, R.P.1    Singh, H.2
  • 24
    • 0032504051 scopus 로고    scopus 로고
    • Loops, lineage, and leukemia
    • Enver T., and Greaves M. Loops, lineage, and leukemia. Cell 94 (1998) 9-12
    • (1998) Cell , vol.94 , pp. 9-12
    • Enver, T.1    Greaves, M.2
  • 25
    • 0027261321 scopus 로고
    • Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors
    • Fairbairn L.J., Cowling G.J., Reipert B.M., and Dexter T.M. Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74 (1993) 823-832
    • (1993) Cell , vol.74 , pp. 823-832
    • Fairbairn, L.J.1    Cowling, G.J.2    Reipert, B.M.3    Dexter, T.M.4
  • 26
    • 0034662159 scopus 로고    scopus 로고
    • Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages
    • Faust N., Varas F., Kelly L.M., Heck S., and Graf T. Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood 96 (2000) 719-726
    • (2000) Blood , vol.96 , pp. 719-726
    • Faust, N.1    Varas, F.2    Kelly, L.M.3    Heck, S.4    Graf, T.5
  • 29
    • 33746208874 scopus 로고    scopus 로고
    • New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors
    • Forsberg E.C., Serwold T., Kogan S., Weissman I.L., and Passegue E. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell 126 (2006) 415-426
    • (2006) Cell , vol.126 , pp. 415-426
    • Forsberg, E.C.1    Serwold, T.2    Kogan, S.3    Weissman, I.L.4    Passegue, E.5
  • 31
    • 0029926485 scopus 로고    scopus 로고
    • Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1
    • Fujiwara Y., Browne C.P., Cunniff K., Goff S.C., and Orkin S.H. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc. Natl. Acad. Sci. USA 93 (1996) 12355-12358
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12355-12358
    • Fujiwara, Y.1    Browne, C.P.2    Cunniff, K.3    Goff, S.C.4    Orkin, S.H.5
  • 32
    • 0942266030 scopus 로고    scopus 로고
    • Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development
    • Fujiwara Y., Chang A.N., Williams A.M., and Orkin S.H. Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood 103 (2004) 583-585
    • (2004) Blood , vol.103 , pp. 583-585
    • Fujiwara, Y.1    Chang, A.N.2    Williams, A.M.3    Orkin, S.H.4
  • 33
    • 0033989686 scopus 로고    scopus 로고
    • Mast cells and basophils
    • Galli S.J. Mast cells and basophils. Curr. Opin. Hematol. 7 (2000) 32-39
    • (2000) Curr. Opin. Hematol. , vol.7 , pp. 32-39
    • Galli, S.J.1
  • 34
    • 0036566226 scopus 로고    scopus 로고
    • Differentiation plasticity of hematopoietic cells
    • Graf T. Differentiation plasticity of hematopoietic cells. Blood 99 (2002) 3089-3101
    • (2002) Blood , vol.99 , pp. 3089-3101
    • Graf, T.1
  • 35
    • 0026723417 scopus 로고
    • Chicken "erythroid" cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent
    • Graf T., McNagny K., Brady G., and Frampton J. Chicken "erythroid" cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent. Cell 70 (1992) 201-213
    • (1992) Cell , vol.70 , pp. 201-213
    • Graf, T.1    McNagny, K.2    Brady, G.3    Frampton, J.4
  • 36
    • 0035171693 scopus 로고    scopus 로고
    • Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing
    • Gurish M.F., Tao H., Abonia J.P., Arya A., Friend D.S., Parker C.M., and Austen K.F. Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing. J. Exp. Med. 194 (2001) 1243-1252
    • (2001) J. Exp. Med. , vol.194 , pp. 1243-1252
    • Gurish, M.F.1    Tao, H.2    Abonia, J.P.3    Arya, A.4    Friend, D.S.5    Parker, C.M.6    Austen, K.F.7
  • 38
    • 31444431706 scopus 로고    scopus 로고
    • Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors
    • Hsu C.L., King-Fleischman A.G., Lai A.Y., Matsumoto Y., Weissman I.L., and Kondo M. Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors. Proc. Natl. Acad. Sci. USA 103 (2006) 672-677
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 672-677
    • Hsu, C.L.1    King-Fleischman, A.G.2    Lai, A.Y.3    Matsumoto, Y.4    Weissman, I.L.5    Kondo, M.6
  • 40
    • 0036669273 scopus 로고    scopus 로고
    • Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
    • Igarashi H., Gregory S.C., Yokota T., Sakaguchi N., and Kincade P.W. Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 17 (2002) 117-130
    • (2002) Immunity , vol.17 , pp. 117-130
    • Igarashi, H.1    Gregory, S.C.2    Yokota, T.3    Sakaguchi, N.4    Kincade, P.W.5
  • 41
    • 0035353180 scopus 로고    scopus 로고
    • Localization of recombination activating gene 1/green fluorescent protein (RAG1/GFP) expression in secondary lymphoid organs after immunization with T-dependent antigens in rag1/gfp knockin mice
    • Igarashi H., Kuwata N., Kiyota K., Sumita K., Suda T., Ono S., Bauer S.R., and Sakaguchi N. Localization of recombination activating gene 1/green fluorescent protein (RAG1/GFP) expression in secondary lymphoid organs after immunization with T-dependent antigens in rag1/gfp knockin mice. Blood 97 (2001) 2680-2687
    • (2001) Blood , vol.97 , pp. 2680-2687
    • Igarashi, H.1    Kuwata, N.2    Kiyota, K.3    Sumita, K.4    Suda, T.5    Ono, S.6    Bauer, S.R.7    Sakaguchi, N.8
  • 42
    • 0026500983 scopus 로고
    • Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation
    • Ikuta K., and Weissman I.L. Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc. Natl. Acad. Sci. USA 89 (1992) 1502-1506
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1502-1506
    • Ikuta, K.1    Weissman, I.L.2
  • 45
    • 0141455931 scopus 로고    scopus 로고
    • GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages
    • Iwasaki H., Mizuno S., Wells R.A., Cantor A.B., Watanabe S., and Akashi K. GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages. Immunity 19 (2003) 451-462
    • (2003) Immunity , vol.19 , pp. 451-462
    • Iwasaki, H.1    Mizuno, S.2    Wells, R.A.3    Cantor, A.B.4    Watanabe, S.5    Akashi, K.6
  • 47
    • 0037515610 scopus 로고    scopus 로고
    • Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion
    • Iwasaki-Arai J., Iwasaki H., Miyamoto T., Watanabe S., and Akashi K. Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion. J. Exp. Med. 197 (2003) 1311-1322
    • (2003) J. Exp. Med. , vol.197 , pp. 1311-1322
    • Iwasaki-Arai, J.1    Iwasaki, H.2    Miyamoto, T.3    Watanabe, S.4    Akashi, K.5
  • 48
    • 0037085568 scopus 로고    scopus 로고
    • Expression of C/EBPbeta from the C/ebpalpha gene locus is sufficient for normal hematopoiesis in vivo
    • Jones L.C., Lin M.L., Chen S.S., Krug U., Hofmann W.K., Lee S., Lee Y.H., and Koeffler H.P. Expression of C/EBPbeta from the C/ebpalpha gene locus is sufficient for normal hematopoiesis in vivo. Blood 99 (2002) 2032-2036
    • (2002) Blood , vol.99 , pp. 2032-2036
    • Jones, L.C.1    Lin, M.L.2    Chen, S.S.3    Krug, U.4    Hofmann, W.K.5    Lee, S.6    Lee, Y.H.7    Koeffler, H.P.8
  • 49
    • 0042662868 scopus 로고    scopus 로고
    • Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo
    • Karsunky H., Merad M., Cozzio A., Weissman I.L., and Manz M.G. Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J. Exp. Med. 198 (2003) 305-313
    • (2003) J. Exp. Med. , vol.198 , pp. 305-313
    • Karsunky, H.1    Merad, M.2    Cozzio, A.3    Weissman, I.L.4    Manz, M.G.5
  • 50
    • 0037544006 scopus 로고    scopus 로고
    • A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis
    • Kaufmann C., Yoshida T., Perotti E.A., Landhuis E., Wu P., and Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. EMBO J. 22 (2003) 2211-2223
    • (2003) EMBO J. , vol.22 , pp. 2211-2223
    • Kaufmann, C.1    Yoshida, T.2    Perotti, E.A.3    Landhuis, E.4    Wu, P.5    Georgopoulos, K.6
  • 51
    • 0037007023 scopus 로고    scopus 로고
    • Lineage infidelity in myeloid cells with TCR gene rearrangement: A latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling
    • King A.G., Kondo M., Scherer D.C., and Weissman I.L. Lineage infidelity in myeloid cells with TCR gene rearrangement: A latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling. Proc. Natl. Acad. Sci. USA 99 (2002) 4508-4513
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4508-4513
    • King, A.G.1    Kondo, M.2    Scherer, D.C.3    Weissman, I.L.4
  • 52
    • 0034699390 scopus 로고    scopus 로고
    • Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines
    • Kondo M., Scherer D.C., Miyamoto T., King A.G., Akashi K., Sugamura K., and Weissman I.L. Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines. Nature 407 (2000) 383-386
    • (2000) Nature , vol.407 , pp. 383-386
    • Kondo, M.1    Scherer, D.C.2    Miyamoto, T.3    King, A.G.4    Akashi, K.5    Sugamura, K.6    Weissman, I.L.7
  • 53
  • 54
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M., Weissman I.L., and Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91 (1997) 661-672
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 55
    • 0034663810 scopus 로고    scopus 로고
    • Chromatin fine structure profiles for a developmentally regulated gene: Reorganization of the lysozyme locus before trans-activator binding and gene expression
    • Kontaraki J., Chen H.H., Riggs A., and Bonifer C. Chromatin fine structure profiles for a developmentally regulated gene: Reorganization of the lysozyme locus before trans-activator binding and gene expression. Genes Dev. 14 (2000) 2106-2122
    • (2000) Genes Dev. , vol.14 , pp. 2106-2122
    • Kontaraki, J.1    Chen, H.H.2    Riggs, A.3    Bonifer, C.4
  • 56
    • 0029066359 scopus 로고
    • GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts
    • Kulessa H., Frampton J., and Graf T. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes Dev. 9 (1995) 1250-1262
    • (1995) Genes Dev. , vol.9 , pp. 1250-1262
    • Kulessa, H.1    Frampton, J.2    Graf, T.3
  • 57
    • 0032740593 scopus 로고    scopus 로고
    • Cutting edge: Absence of expression of RAG1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene
    • Kuwata N., Igarashi H., Ohmura T., Aizawa S., and Sakaguchi N. Cutting edge: Absence of expression of RAG1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene. J. Immunol. 163 (1999) 6355-6359
    • (1999) J. Immunol. , vol.163 , pp. 6355-6359
    • Kuwata, N.1    Igarashi, H.2    Ohmura, T.3    Aizawa, S.4    Sakaguchi, N.5
  • 58
    • 33746906644 scopus 로고    scopus 로고
    • Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors
    • Lai A.Y., and Kondo M. Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. J. Exp. Med. 203 (2006) 1867-1873
    • (2006) J. Exp. Med. , vol.203 , pp. 1867-1873
    • Lai, A.Y.1    Kondo, M.2
  • 59
    • 33644641356 scopus 로고    scopus 로고
    • Determinants of lymphoid-myeloid lineage diversification
    • Laiosa C.V., Stadtfeld M., and Graf T. Determinants of lymphoid-myeloid lineage diversification. Annu. Rev. Immunol. 24 (2006) 705-738
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 705-738
    • Laiosa, C.V.1    Stadtfeld, M.2    Graf, T.3
  • 60
    • 33846257739 scopus 로고    scopus 로고
    • Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors
    • Laiosa C.V., Stadtfeld M., Xie H., de Andres-Aguayo L., and Graf T. Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors. Immunity 25 (2006) 731-744
    • (2006) Immunity , vol.25 , pp. 731-744
    • Laiosa, C.V.1    Stadtfeld, M.2    Xie, H.3    de Andres-Aguayo, L.4    Graf, T.5
  • 62
    • 0028907847 scopus 로고
    • Murine hematopoietic stem and progenitor cells: I. Enrichment and biologic characterization
    • Li C.L., and Johnson G.R. Murine hematopoietic stem and progenitor cells: I. Enrichment and biologic characterization. Blood 85 (1995) 1472-1479
    • (1995) Blood , vol.85 , pp. 1472-1479
    • Li, C.L.1    Johnson, G.R.2
  • 63
    • 0029097145 scopus 로고
    • Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors
    • Mackarehtschian K., Hardin J.D., Moore K.A., Boast S., Goff S.P., and Lemischka I.R. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 3 (1995) 147-161
    • (1995) Immunity , vol.3 , pp. 147-161
    • Mackarehtschian, K.1    Hardin, J.D.2    Moore, K.A.3    Boast, S.4    Goff, S.P.5    Lemischka, I.R.6
  • 65
    • 0035383775 scopus 로고    scopus 로고
    • Dendritic cell potentials of early lymphoid and myeloid progenitors
    • Manz M.G., Traver D., Miyamoto T., Weissman I.L., and Akashi K. Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 97 (2001) 3333-3341
    • (2001) Blood , vol.97 , pp. 3333-3341
    • Manz, M.G.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4    Akashi, K.5
  • 69
    • 0032528354 scopus 로고    scopus 로고
    • Lineage commitment and maturation in hematopoietic cells: The case for extrinsic regulation
    • Metcalf D. Lineage commitment and maturation in hematopoietic cells: The case for extrinsic regulation. Blood 92 (1998) 345-347
    • (1998) Blood , vol.92 , pp. 345-347
    • Metcalf, D.1
  • 70
    • 0036070180 scopus 로고    scopus 로고
    • Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment
    • Miyamoto T., Iwasaki H., Reizis B., Ye M., Graf T., Weissman I.L., and Akashi K. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev. Cell 3 (2002) 137-147
    • (2002) Dev. Cell , vol.3 , pp. 137-147
    • Miyamoto, T.1    Iwasaki, H.2    Reizis, B.3    Ye, M.4    Graf, T.5    Weissman, I.L.6    Akashi, K.7
  • 71
    • 0032212250 scopus 로고    scopus 로고
    • The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors
    • Moritz D.R., Rodewald H.R., Gheyselinck J., and Klemenz R. The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors. J. Immunol. 161 (1998) 4866-4874
    • (1998) J. Immunol. , vol.161 , pp. 4866-4874
    • Moritz, D.R.1    Rodewald, H.R.2    Gheyselinck, J.3    Klemenz, R.4
  • 73
    • 0028534860 scopus 로고
    • The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
    • Morrison S.J., and Weissman I.L. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1 (1994) 661-673
    • (1994) Immunity , vol.1 , pp. 661-673
    • Morrison, S.J.1    Weissman, I.L.2
  • 74
    • 0035313834 scopus 로고    scopus 로고
    • Chromatin remodeling in development and differentiation
    • Muller C., and Leutz A. Chromatin remodeling in development and differentiation. Curr Opin Genet Dev. 11 (2001) 167-174
    • (2001) Curr Opin Genet Dev. , vol.11 , pp. 167-174
    • Muller, C.1    Leutz, A.2
  • 75
    • 0036081059 scopus 로고    scopus 로고
    • Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S
    • Na Nakorn T., Traver D., Weissman I.L., and Akashi K. Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J. Clin. Invest. 109 (2002) 1579-1585
    • (2002) J. Clin. Invest. , vol.109 , pp. 1579-1585
    • Na Nakorn, T.1    Traver, D.2    Weissman, I.L.3    Akashi, K.4
  • 77
    • 0037422537 scopus 로고    scopus 로고
    • Characterization of mouse clonogenic megakaryocyte progenitors
    • Nakorn T.N., Miyamoto T., and Weissman I.L. Characterization of mouse clonogenic megakaryocyte progenitors. Proc. Natl. Acad. Sci. USA 100 (2003) 205-210
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 205-210
    • Nakorn, T.N.1    Miyamoto, T.2    Weissman, I.L.3
  • 78
    • 0032146794 scopus 로고    scopus 로고
    • PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors
    • Nerlov C., and Graf T. PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev. 12 (1998) 2403-2412
    • (1998) Genes Dev. , vol.12 , pp. 2403-2412
    • Nerlov, C.1    Graf, T.2
  • 79
    • 0034656393 scopus 로고    scopus 로고
    • GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription
    • Nerlov C., Querfurth E., Kulessa H., and Graf T. GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription. Blood 95 (2000) 2543-2551
    • (2000) Blood , vol.95 , pp. 2543-2551
    • Nerlov, C.1    Querfurth, E.2    Kulessa, H.3    Graf, T.4
  • 81
    • 0027751556 scopus 로고
    • Interleukin-2 receptor gamma chain: A functional component of the interleukin-7 receptor
    • Noguchi M., Nakamura Y., Russell S.M., Ziegler S.F., Tsang M., Cao X., and Leonard W.J. Interleukin-2 receptor gamma chain: A functional component of the interleukin-7 receptor. Science 262 (1993) 1877-1880
    • (1993) Science , vol.262 , pp. 1877-1880
    • Noguchi, M.1    Nakamura, Y.2    Russell, S.M.3    Ziegler, S.F.4    Tsang, M.5    Cao, X.6    Leonard, W.J.7
  • 82
    • 13244277736 scopus 로고    scopus 로고
    • Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors
    • Nutt S.L., Metcalf D., D'Amico A., Polli M., and Wu L. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J. Exp. Med. 201 (2005) 221-231
    • (2005) J. Exp. Med. , vol.201 , pp. 221-231
    • Nutt, S.L.1    Metcalf, D.2    D'Amico, A.3    Polli, M.4    Wu, L.5
  • 83
    • 0032599946 scopus 로고    scopus 로고
    • Stochastic model revisited
    • Ogawa M. Stochastic model revisited. Int. J. Hematol. 69 (1999) 2-5
    • (1999) Int. J. Hematol. , vol.69 , pp. 2-5
    • Ogawa, M.1
  • 85
    • 0034303586 scopus 로고    scopus 로고
    • Diversification of haematopoietic stem cells to specific lineages
    • Orkin S.H. Diversification of haematopoietic stem cells to specific lineages. Nat. Rev. Genet. 1 (2000) 57-64
    • (2000) Nat. Rev. Genet. , vol.1 , pp. 57-64
    • Orkin, S.H.1
  • 86
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34- low/negative hematopoietic stem cell
    • Osawa M., Hanada K., Hamada H., and Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34- low/negative hematopoietic stem cell. Science 273 (1996) 242-245
    • (1996) Science , vol.273 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 88
    • 0030007289 scopus 로고    scopus 로고
    • Expression of murine CD38 defines a population of long-term reconstituting hematopoietic stem cells
    • Randall T.D., Lund F.E., Howard M.C., and Weissman I.L. Expression of murine CD38 defines a population of long-term reconstituting hematopoietic stem cells. Blood 87 (1996) 4057-4067
    • (1996) Blood , vol.87 , pp. 4057-4067
    • Randall, T.D.1    Lund, F.E.2    Howard, M.C.3    Weissman, I.L.4
  • 89
    • 0037100304 scopus 로고    scopus 로고
    • Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: Possible role in lineage commitment decisions
    • Reddy V.A., Iwama A., Iotzova G., Schulz M., Elsasser A., Vangala R.K., Tenen D.G., Hiddemann W., and Behre G. Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: Possible role in lineage commitment decisions. Blood 100 (2002) 483-490
    • (2002) Blood , vol.100 , pp. 483-490
    • Reddy, V.A.1    Iwama, A.2    Iotzova, G.3    Schulz, M.4    Elsasser, A.5    Vangala, R.K.6    Tenen, D.G.7    Hiddemann, W.8    Behre, G.9
  • 90
    • 0033577844 scopus 로고    scopus 로고
    • Expression of the mouse pre-T cell receptor alpha gene is controlled by an upstream region containing a transcriptional enhancer
    • Reizis B., and Leder P. Expression of the mouse pre-T cell receptor alpha gene is controlled by an upstream region containing a transcriptional enhancer. J. Exp. Med. 189 (1999) 1669-1678
    • (1999) J. Exp. Med. , vol.189 , pp. 1669-1678
    • Reizis, B.1    Leder, P.2
  • 91
    • 0033151624 scopus 로고    scopus 로고
    • Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: Functional antagonism in erythroid cells
    • Rekhtman N., Radparvar F., Evans T., and Skoultchi A.I. Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: Functional antagonism in erythroid cells. Genes Dev. 13 (1999) 1398-1411
    • (1999) Genes Dev. , vol.13 , pp. 1398-1411
    • Rekhtman, N.1    Radparvar, F.2    Evans, T.3    Skoultchi, A.I.4
  • 92
    • 33846622099 scopus 로고    scopus 로고
    • Transcription factors in myeloid development: Balancing differentiation with transformation
    • Rosenbauer F., and Tenen D.G. Transcription factors in myeloid development: Balancing differentiation with transformation. Nat. Rev. Immunol. 7 (2007) 105-117
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 105-117
    • Rosenbauer, F.1    Tenen, D.G.2
  • 94
    • 34250203551 scopus 로고    scopus 로고
    • Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals
    • this issue
    • Rothenberg E.V. Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals. Immunity 26 (2007) 690-702 this issue
    • (2007) Immunity , vol.26 , pp. 690-702
    • Rothenberg, E.V.1
  • 95
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
    • Schmitt T.M., and Zuniga-Pflucker J.C. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 17 (2002) 749-756
    • (2002) Immunity , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 96
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • Scott E.W., Simon M.C., Anastasi J., and Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265 (1994) 1573-1577
    • (1994) Science , vol.265 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 97
  • 98
    • 0030926006 scopus 로고    scopus 로고
    • A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
    • Shivdasani R.A., Fujiwara Y., McDevitt M.A., and Orkin S.H. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 16 (1997) 3965-3973
    • (1997) EMBO J. , vol.16 , pp. 3965-3973
    • Shivdasani, R.A.1    Fujiwara, Y.2    McDevitt, M.A.3    Orkin, S.H.4
  • 99
    • 33644643428 scopus 로고    scopus 로고
    • Gene regulatory networks and the determination of lymphoid cell fates
    • Singh H., and Pongubala J.M. Gene regulatory networks and the determination of lymphoid cell fates. Curr. Opin. Immunol. 18 (2006) 116-120
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 116-120
    • Singh, H.1    Pongubala, J.M.2
  • 100
    • 0036797682 scopus 로고    scopus 로고
    • Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool
    • Sitnicka E., Bryder D., Theilgaard-Monch K., Buza-Vidas N., Adolfsson J., and Jacobsen S.E. Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool. Immunity 17 (2002) 463-472
    • (2002) Immunity , vol.17 , pp. 463-472
    • Sitnicka, E.1    Bryder, D.2    Theilgaard-Monch, K.3    Buza-Vidas, N.4    Adolfsson, J.5    Jacobsen, S.E.6
  • 102
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude G.J., Heimfeld S., and Weissman I.L. Purification and characterization of mouse hematopoietic stem cells. Science 241 (1988) 58-62
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 103
    • 0141465061 scopus 로고    scopus 로고
    • The role of FLT3 in haematopoietic malignancies
    • Stirewalt D.L., and Radich J.P. The role of FLT3 in haematopoietic malignancies. Nat. Rev. Cancer 3 (2003) 650-665
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 650-665
    • Stirewalt, D.L.1    Radich, J.P.2
  • 104
    • 0343099332 scopus 로고
    • Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations
    • Suda T., Suda J., and Ogawa M. Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations. Proc. Natl. Acad. Sci. USA 80 (1983) 6689-6693
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6689-6693
    • Suda, T.1    Suda, J.2    Ogawa, M.3
  • 106
    • 0037315894 scopus 로고    scopus 로고
    • Disruption of differentiation in human cancer: AML shows the way
    • Tenen D.G. Disruption of differentiation in human cancer: AML shows the way. Nat. Rev. Cancer 3 (2003) 89-101
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 89-101
    • Tenen, D.G.1
  • 107
    • 2442641790 scopus 로고    scopus 로고
    • Lineage commitment and developmental plasticity in early lymphoid progenitor subsets
    • Traver D., and Akashi K. Lineage commitment and developmental plasticity in early lymphoid progenitor subsets. Adv. Immunol. 83 (2004) 1-54
    • (2004) Adv. Immunol. , vol.83 , pp. 1-54
    • Traver, D.1    Akashi, K.2
  • 108
  • 109
    • 0030926190 scopus 로고    scopus 로고
    • Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation
    • Tsai F.Y., and Orkin S.H. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 89 (1997) 3636-3643
    • (1997) Blood , vol.89 , pp. 3636-3643
    • Tsai, F.Y.1    Orkin, S.H.2
  • 110
    • 0025876999 scopus 로고
    • Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter
    • Tsai S.F., Strauss E., and Orkin S.H. Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter. Genes Dev. 5 (1991) 919-931
    • (1991) Genes Dev. , vol.5 , pp. 919-931
    • Tsai, S.F.1    Strauss, E.2    Orkin, S.H.3
  • 111
    • 0032522474 scopus 로고    scopus 로고
    • Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
    • Tsang A.P., Fujiwara Y., Hom D.B., and Orkin S.H. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes Dev. 12 (1998) 1176-1188
    • (1998) Genes Dev. , vol.12 , pp. 1176-1188
    • Tsang, A.P.1    Fujiwara, Y.2    Hom, D.B.3    Orkin, S.H.4
  • 112
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • von Freeden-Jeffry U., Vieira P., Lucian L.A., McNeil T., Burdach S.E., and Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181 (1995) 1519-1526
    • (1995) J. Exp. Med. , vol.181 , pp. 1519-1526
    • von Freeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3    McNeil, T.4    Burdach, S.E.5    Murray, R.6
  • 113
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang J.H., Nichogiannopoulou A., Wu L., Sun L., Sharpe A.H., Bigby M., and Georgopoulos K. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5 (1996) 537-549
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.H.1    Nichogiannopoulou, A.2    Wu, L.3    Sun, L.4    Sharpe, A.H.5    Bigby, M.6    Georgopoulos, K.7
  • 114
    • 0037375763 scopus 로고    scopus 로고
    • Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors
    • Warren L.A., and Rothenberg E.V. Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors. Curr. Opin. Immunol. 15 (2003) 166-175
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 166-175
    • Warren, L.A.1    Rothenberg, E.V.2
  • 115
    • 0033729622 scopus 로고    scopus 로고
    • Roles of mast cells and basophils in innate and acquired immunity
    • Wedemeyer J., Tsai M., and Galli S.J. Roles of mast cells and basophils in innate and acquired immunity. Curr. Opin. Immunol. 12 (2000) 624-631
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 624-631
    • Wedemeyer, J.1    Tsai, M.2    Galli, S.J.3
  • 116
    • 0022137507 scopus 로고
    • Assembly and propagation of repressed and depressed chromosomal states
    • Weintraub H. Assembly and propagation of repressed and depressed chromosomal states. Cell 42 (1985) 705-711
    • (1985) Cell , vol.42 , pp. 705-711
    • Weintraub, H.1
  • 117
    • 2542455620 scopus 로고    scopus 로고
    • Stepwise reprogramming of B cells into macrophages
    • Xie H., Ye M., Feng R., and Graf T. Stepwise reprogramming of B cells into macrophages. Cell 117 (2004) 663-676
    • (2004) Cell , vol.117 , pp. 663-676
    • Xie, H.1    Ye, M.2    Feng, R.3    Graf, T.4
  • 118
    • 0344276481 scopus 로고    scopus 로고
    • Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential
    • Ye M., Iwasaki H., Laiosa C.V., Stadtfeld M., Xie H., Heck S., Clausen B., Akashi K., and Graf T. Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential. Immunity 19 (2003) 689-699
    • (2003) Immunity , vol.19 , pp. 689-699
    • Ye, M.1    Iwasaki, H.2    Laiosa, C.V.3    Stadtfeld, M.4    Xie, H.5    Heck, S.6    Clausen, B.7    Akashi, K.8    Graf, T.9
  • 120
    • 0037013924 scopus 로고    scopus 로고
    • Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo
    • Yu C., Cantor A.B., Yang H., Browne C., Wells R.A., Fujiwara Y., and Orkin S.H. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J. Exp. Med. 195 (2002) 1387-1395
    • (2002) J. Exp. Med. , vol.195 , pp. 1387-1395
    • Yu, C.1    Cantor, A.B.2    Yang, H.3    Browne, C.4    Wells, R.A.5    Fujiwara, Y.6    Orkin, S.H.7
  • 121
    • 0031029557 scopus 로고    scopus 로고
    • Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha- deficient mice
    • Zhang D.E., Zhang P., Wang N.D., Hetherington C.J., Darlington G.J., and Tenen D.G. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha- deficient mice. Proc. Natl. Acad. Sci. USA 94 (1997) 569-574
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 569-574
    • Zhang, D.E.1    Zhang, P.2    Wang, N.D.3    Hetherington, C.J.4    Darlington, G.J.5    Tenen, D.G.6


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