-
1
-
-
24644524532
-
Mechanisms of sudden cardiac death
-
Rubart, M & D. P. Zipes: Mechanisms of sudden cardiac death. J Clin Invest 115, 2305-2315 (2005)
-
(2005)
J Clin Invest
, vol.115
, pp. 2305-2315
-
-
Rubart, M.1
Zipes, D.P.2
-
2
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
Keating M. T. & M. C. Sanguinetti: Molecular and cellular mechanisms of cardiac arrhythmias. Cell 104, 569-80 (2001)
-
(2001)
Cell
, vol.104
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
3
-
-
0037049999
-
Cardiac channelopathies
-
Marban E: Cardiac channelopathies. Nature 415, 213-218 (2002)
-
(2002)
Nature
, vol.415
, pp. 213-218
-
-
Marban, E.1
-
4
-
-
1542298958
-
Pharmacology of cardiac potassium channels
-
Tamargo J, R. Caballero, R. Gómez, C. Valenzuela & E. Delpón: Pharmacology of cardiac potassium channels: Cardiovasc Res 62, 9-33 (2004)
-
(2004)
Cardiovasc Res
, vol.62
, pp. 9-33
-
-
Tamargo, J.1
Caballero, R.2
Gómez, R.3
Valenzuela, C.4
Delpón, E.5
-
5
-
-
0038387491
-
Electrophysiological phenotyping in engineered mice
-
Berul C.I.: Electrophysiological phenotyping in engineered mice. Physiol Genomics 13, 207-216 (2003)
-
(2003)
Physiol Genomics
, vol.13
, pp. 207-216
-
-
Berul, C.I.1
-
6
-
-
2342566988
-
Studying cardiac arrhythmias in the mouse - a reasonable model for probing mechanisms?
-
Nerbonne J. M: Studying cardiac arrhythmias in the mouse - a reasonable model for probing mechanisms?. Trends Cardiovasc Med 14, 83-93 (2004)
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 83-93
-
-
Nerbonne, J.M.1
-
7
-
-
25444529765
-
-
Nerbonne J. M & R. S. Kass RS: Molecular physiology of cardiac repolarization. Physiol Rev 85, 1205-1253 (2005)
-
Nerbonne J. M & R. S. Kass RS: Molecular physiology of cardiac repolarization. Physiol Rev 85, 1205-1253 (2005)
-
-
-
-
8
-
-
0032494172
-
Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit
-
Barry D. M, H. Xu, R. B. Schuessler & J. M. Nerbonne: Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit. Circ Res 83, 560-567 (1998)
-
(1998)
Circ Res
, vol.83
, pp. 560-567
-
-
Barry, D.M.1
Xu, H.2
Schuessler, R.B.3
Nerbonne, J.M.4
-
9
-
-
0033215099
-
Attenuation of the slow component of delayed rectification, action potential prolongation, and triggered activity in mice expressing a dominant-negative Kv2 alpha subunit
-
Xu H, D. M. Barry, H. Li, S. Brunet, W. Guo & J. M. Nerbonne: Attenuation of the slow component of delayed rectification, action potential prolongation, and triggered activity in mice expressing a dominant-negative Kv2 alpha subunit. Circ Res 85, 623-633 (1999)
-
(1999)
Circ Res
, vol.85
, pp. 623-633
-
-
Xu, H.1
Barry, D.M.2
Li, H.3
Brunet, S.4
Guo, W.5
Nerbonne, J.M.6
-
10
-
-
0034617143
-
to,s early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1.4 and expressing a dominant-negative Kv4 alpha subunit
-
to,s early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1.4 and expressing a dominant-negative Kv4 alpha subunit. Circ Res 87, 73-79 (2000)
-
(2000)
Circ Res
, vol.87
, pp. 73-79
-
-
Guo, W.1
Li, H.2
London, B.3
Nerbonne, J.M.4
-
11
-
-
85118093830
-
-
to,f is eliminated in mouse ventricular myocytes isolated from mice lacking Kv4.2: what is the role of Kv4.3?. Biophys J78, 451 A (2000)
-
to,f is eliminated in mouse ventricular myocytes isolated from mice lacking Kv4.2: what is the role of Kv4.3?. Biophys J78, 451 A (2000)
-
-
-
-
13
-
-
0034822465
-
K,slow
-
K,slow. Am J Physiol Heart Circ Physiol 281, H1201-H1209 (2001)
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.281
-
-
Brunner, M.1
Guo, W.2
Mitchell, G.F.3
Buckett, P.D.4
Nerbonne, J.M.5
Koren, G.6
-
14
-
-
0032539808
-
Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel
-
London B, A. Jeron, J. Zhou, P. Buckett, X. Han, G. F. Mitchell & G. Koren: Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel. Proc Natl Acad Sci U S A 95, 2926-2931 (1998)
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2926-2931
-
-
London, B.1
Jeron, A.2
Zhou, J.3
Buckett, P.4
Han, X.5
Mitchell, G.F.6
Koren, G.7
-
15
-
-
0037305084
-
K, slow2, in Kv1DN mice is abolished by crossbreeding with Kv2DN mice
-
K, slow2, in Kv1DN mice is abolished by crossbreeding with Kv2DN mice. Am J Physiol Heart Circ Physiol 284, H491-H500 (2003)
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Zhou, J.1
Kodirov, S.2
Murata, M.3
Buckett, P.D.4
Nerbonne, J.M.5
Koren, G.6
-
16
-
-
0034599079
-
Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotesreentrant ventricular tachycardia
-
Baker L. C, B. London, B. R. Choi, G. Koren & G. Salama: Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotesreentrant ventricular tachycardia. Circ Res 86, 396-407 (2000)
-
(2000)
Circ Res
, vol.86
, pp. 396-407
-
-
Baker, L.C.1
London, B.2
Choi, B.R.3
Koren, G.4
Salama, G.5
-
17
-
-
0033524661
-
Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system
-
Kupershmidt S, T. Yang, M. E. Anderson, A. Wessels, K. D. Niswender, M. A. Magnuson & D. M. Roden: Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system. Circ Res 84, 146152 (1999)
-
(1999)
Circ Res
, vol.84
, pp. 146152
-
-
Kupershmidt, S.1
Yang, T.2
Anderson, M.E.3
Wessels, A.4
Niswender, K.D.5
Magnuson, M.A.6
Roden, D.M.7
-
18
-
-
0033948513
-
Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype
-
Jeron A, G. F. Mitchell, J. Zhou, M. Murata, B. London, P. Buckett, S. D. Wiviott & G. Koren: Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype. Am J Physiol Heart Circ Physiol 278, H1891-H1898 (2000)
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
-
-
Jeron, A.1
Mitchell, G.F.2
Zhou, J.3
Murata, M.4
London, B.5
Buckett, P.6
Wiviott, S.D.7
Koren, G.8
-
19
-
-
18244408825
-
to and confers susceptibility to ventricular tachycardia
-
to and confers susceptibility to ventricular tachycardia. Cell 107, 801-813 (2001)
-
(2001)
Cell
, vol.107
, pp. 801-813
-
-
Kuo, H.C.1
Cheng, C.F.2
Clark, R.B.3
Lin, J.J.4
Lin, J.L.5
Hoshijima, M.6
Nguyen-Tran, V.T.7
Gu, Y.8
Ikeda, Y.9
Chu, P.H.10
Ross, J.11
Giles, W.R.12
Chien, K.R.13
-
20
-
-
22544483871
-
The long QT syndrome: Therapeutic implications of a genetic diagnosis
-
Shimizu W: The long QT syndrome: therapeutic implications of a genetic diagnosis. Cardiovasc Res 67, 347-356 (2005)
-
(2005)
Cardiovasc Res
, vol.67
, pp. 347-356
-
-
Shimizu, W.1
-
21
-
-
0035038277
-
Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part I: Phenotypic characterisation
-
Demolombe S, G. Lande, F. Charpentier, M. A. van Roon, M. J. van den Hoff, G. Toumaniantz, I. Baro, G. Guihard, N. Le Berre, A. Corbier, J. de Bakker, T. Opthof, A. Wilde, A. F. Moorman & D. Escande: Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part I: Phenotypic characterisation. Cardiovasc Res 50, 314-327 (2001)
-
(2001)
Cardiovasc Res
, vol.50
, pp. 314-327
-
-
Demolombe, S.1
Lande, G.2
Charpentier, F.3
van Roon, M.A.4
van den Hoff, M.J.5
Toumaniantz, G.6
Baro, I.7
Guihard, G.8
Le Berre, N.9
Corbier, A.10
de Bakker, J.11
Opthof, T.12
Wilde, A.13
Moorman, A.F.14
Escande, D.15
-
22
-
-
0034518479
-
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice
-
Lee M. P, J. D. Ravenel, R. J. Hu, L. R. Lustig, G. Tomaselli, R. D. Berger, S. A. Brandenburg, T. J. Litzi, T. E. Bunton, C. Limb, H. Francis, M. Gorelikow, H. Gu, K. Washington, P. Argani, J. R. Goldenring, R. J. Coffey & A. P. Feinberg: Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. J Clin Invest 106, 1447-1455 (2000)
-
(2000)
J Clin Invest
, vol.106
, pp. 1447-1455
-
-
Lee, M.P.1
Ravenel, J.D.2
Hu, R.J.3
Lustig, L.R.4
Tomaselli, G.5
Berger, R.D.6
Brandenburg, S.A.7
Litzi, T.J.8
Bunton, T.E.9
Limb, C.10
Francis, H.11
Gorelikow, M.12
Gu, H.13
Washington, K.14
Argani, P.15
Goldenring, J.R.16
Coffey, R.J.17
Feinberg, A.P.18
-
23
-
-
0035956935
-
Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome
-
Casimiro M. C, B. C. Knollmann, S. N. Ebert, J. C. Jr. Vary, A. E. Greene, M. R. Franz, A. Grinberg, S. P. Huang & K. Pfeifer: Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome. Proc Natl Acad Sci U S A 98, 2526-2531 (2001)
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2526-2531
-
-
Casimiro, M.C.1
Knollmann, B.C.2
Ebert, S.N.3
Vary Jr., J.C.4
Greene, A.E.5
Franz, M.R.6
Grinberg, A.7
Huang, S.P.8
Pfeifer, K.9
-
24
-
-
22144496096
-
Atrial fibrillation in KCNE1-null mice
-
Temple J, P. Frias, J. Rottman, T. Yang, Y. Wu, E. E. Verheijck, W. Zhang, C. Siprachanh, H. Kanki, J. B. Atkinson, P. King, M. E. Anderson, S. Kupershmidt & D. M. Roden: Atrial fibrillation in KCNE1-null mice. Circ Res 97, 62-69 (2005)
-
(2005)
Circ Res
, vol.97
, pp. 62-69
-
-
Temple, J.1
Frias, P.2
Rottman, J.3
Yang, T.4
Wu, Y.5
Verheijck, E.E.6
Zhang, W.7
Siprachanh, C.8
Kanki, H.9
Atkinson, J.B.10
King, P.11
Anderson, M.E.12
Kupershmidt, S.13
Roden, D.M.14
-
25
-
-
0032578771
-
Adult KCNE1-knockout mice exhibit a mild cardiac cellular phenotype
-
Charpentier F, J. Merot, D. Riochet, H. Le Marec & D. Escande: Adult KCNE1-knockout mice exhibit a mild cardiac cellular phenotype. Biochem Biophys Res Commun 251, 806-810(1998)
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 806-810
-
-
Charpentier, F.1
Merot, J.2
Riochet, D.3
Le Marec, H.4
Escande, D.5
-
26
-
-
0032514164
-
+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome
-
+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome. Circ Res 83, 95-102 (1998)
-
(1998)
Circ Res
, vol.83
, pp. 95-102
-
-
Drici, M.D.1
Arrighi, I.2
Chouabe, C.3
Mann, J.R.4
Lazdunski, M.5
Romey, G.6
Barhanin, J.7
-
27
-
-
0035254170
-
Cardiac sodium channel and inherited arrhythmia syndromes
-
Bezzina C. R, M. B. Rook & A. A. M. Wilde: Cardiac sodium channel and inherited arrhythmia syndromes. Cardiovasc Res 49, 257-271 (2001)
-
(2001)
Cardiovasc Res
, vol.49
, pp. 257-271
-
-
Bezzina, C.R.1
Rook, M.B.2
Wilde, A.A.M.3
-
28
-
-
0034800266
-
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome
-
Nuyens D, M. Stengl, S. Dugarmaa, T. Rossenbacker, V. Compernolle, Y. Rudy, J. F. Smits, W. Flameng, C. E. Clancy, L. Moons, M. A. Vos, M. Dewerchin, K. Benndorf, D. Collen, E. Carmeliet & P. Carmeliet: Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nat Med 7, 1021-1027 (2001)
-
(2001)
Nat Med
, vol.7
, pp. 1021-1027
-
-
Nuyens, D.1
Stengl, M.2
Dugarmaa, S.3
Rossenbacker, T.4
Compernolle, V.5
Rudy, Y.6
Smits, J.F.7
Flameng, W.8
Clancy, C.E.9
Moons, L.10
Vos, M.A.11
Dewerchin, M.12
Benndorf, K.13
Collen, D.14
Carmeliet, E.15
Carmeliet, P.16
-
29
-
-
0037377248
-
Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice
-
Fabritz L, P. Kirchhof, M. R. Franz, D. Nuyens, T. Rossenbacker, A. Ottenhof, W. Haverkamp, G. Breithardt, E. Carmeliet & P. Carmeliet: Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice. Cardiovasc Res 57, 1085-1093 (2003)
-
(2003)
Cardiovasc Res
, vol.57
, pp. 1085-1093
-
-
Fabritz, L.1
Kirchhof, P.2
Franz, M.R.3
Nuyens, D.4
Rossenbacker, T.5
Ottenhof, A.6
Haverkamp, W.7
Breithardt, G.8
Carmeliet, E.9
Carmeliet, P.10
-
30
-
-
18344362987
-
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a
-
Papadatos G. A, P. M. Wallerstein, C. E. Head, R. Ratcliff, P. A. Brady, K. Benndorf, R. C. Saumarez, A. E. Trezise, C. L. Huang, J. I. Vandenberg, W. H. Colledge & A. A. Grace: Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A 99, 6210-6215 (2002)
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 6210-6215
-
-
Papadatos, G.A.1
Wallerstein, P.M.2
Head, C.E.3
Ratcliff, R.4
Brady, P.A.5
Benndorf, K.6
Saumarez, R.C.7
Trezise, A.E.8
Huang, C.L.9
Vandenberg, J.I.10
Colledge, W.H.11
Grace, A.A.12
-
31
-
-
20244376320
-
Mouse model of SCNSA-linked hereditary Lenegre's disease: Age-related conduction slowing and myocardial fibrosis
-
Royer A, T. A. Van Veen, S. Le Bouter, C. Marionneau, V. Griol-Charhbili, A-L. Léoni, M. Steenman, H. V. Van Rijen, S. Demolombe, C. A. Goddard, C. Richer, B. Escoubet, J. Jarry-Guichard, W. H. Colledge, D. Gros, J. M. Bakker, A.A. Grace, D. Escande & F. Charpentier: Mouse model of SCNSA-linked hereditary Lenegre's disease: age-related conduction slowing and myocardial fibrosis. Circulation 111, 1738-1746 (2005)
-
(2005)
Circulation
, vol.111
, pp. 1738-1746
-
-
Royer, A.1
Van Veen, T.A.2
Le Bouter, S.3
Marionneau, C.4
Griol-Charhbili, V.5
Léoni, A.-L.6
Steenman, M.7
Van Rijen, H.V.8
Demolombe, S.9
Goddard, C.A.10
Richer, C.11
Escoubet, B.12
Jarry-Guichard, J.13
Colledge, W.H.14
Gros, D.15
Bakker, J.M.16
Grace, A.A.17
Escande, D.18
Charpentier, F.19
-
32
-
-
4244201143
-
QT interval prolongation and arrhythmias in heterozygous MERG1-targeted mice
-
London B & X. Pan: QT interval prolongation and arrhythmias in heterozygous MERG1-targeted mice. Circulation 98, 279 (1998)
-
(1998)
Circulation
, vol.98
, pp. 279
-
-
London, B.1
Pan, X.2
-
33
-
-
0032556030
-
+ current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice
-
+ current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice. Circ Res 83, 668-678 (1998)
-
(1998)
Circ Res
, vol.83
, pp. 668-678
-
-
Babij, P.1
Askew, G.R.2
Nieuwenhuijsen, B.3
Su, C.M.4
Bridal, T.R.5
Jow, B.6
Argentieri, T.M.7
Kulik, J.8
DeGennaro, L.J.9
Spinelli, W.10
Colatsky, T.J.11
-
34
-
-
0037371841
-
Selective knockout of mouse ERG1 B potassium channel eliminates IKT in adult ventricular myocytes and elicits episodes of abrupt sinus bradycardia
-
Lees-Miller J. P, J. Guo, J. R. Somers, D. E. Roach, R. S. Sheldon, D. E. Rancourt & H. J. Duff : Selective knockout of mouse ERG1 B potassium channel eliminates IKT in adult ventricular myocytes and elicits episodes of abrupt sinus bradycardia. Mol Cell Biol 23, 1856-1862 (2003)
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1856-1862
-
-
Lees-Miller, J.P.1
Guo, J.2
Somers, J.R.3
Roach, D.E.4
Sheldon, R.S.5
Rancourt, D.E.6
Duff, H.J.7
-
35
-
-
19944394825
-
+ channels in the mouse heart exerts anti-arrhythmic activity
-
+ channels in the mouse heart exerts anti-arrhythmic activity. Cardiovasc Res 65, 128-137(2005)
-
(2005)
Cardiovasc Res
, vol.65
, pp. 128-137
-
-
Royer, A.1
Demolombe, S.2
El Harchi, A.3
Le Quang, K.4
Piron, J.5
Toumaniantz, G.6
Mazurais, D.7
Bellocq, C.8
Lande, G.9
Terrenoire, C.10
Motoike, H.K.11
Chevallier, J.C.12
Loussouarn, G.13
Clancy, C.E.14
Escande, D.15
Charpentier, F.16
-
36
-
-
0028819671
-
Mapping of a gene for long QT syndrome to chromosome 4q25-27
-
Schott J. J, F. Charpentier, S. Peltier, P. Foley, E. Drouin, J. B. Bouhour, P. Donnelly, G. Vergnaud, L. Bachner, J. P. Moisan, et al: Mapping of a gene for long QT syndrome to chromosome 4q25-27. Am J Hum Genet 57, 1114-1122 (1995)
-
(1995)
Am J Hum Genet
, vol.57
, pp. 1114-1122
-
-
Schott, J.J.1
Charpentier, F.2
Peltier, S.3
Foley, P.4
Drouin, E.5
Bouhour, J.B.6
Donnelly, P.7
Vergnaud, G.8
Bachner, L.9
Moisan, J.P.10
-
37
-
-
0242464931
-
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
-
Mohler P. J, J. J. Schott, A. O. Gramolini, K. W. Dilly, S. Guatimosim, W. H. duBell, L. S. Song, K. Haurogne, F. Kyndt, M. E. Ali, T. B. Rogers, W. J. Lederer, D. Escande, H. Le Marec & V. Bennett: Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature 421, 634-639 (2003)
-
(2003)
Nature
, vol.421
, pp. 634-639
-
-
Mohler, P.J.1
Schott, J.J.2
Gramolini, A.O.3
Dilly, K.W.4
Guatimosim, S.5
duBell, W.H.6
Song, L.S.7
Haurogne, K.8
Kyndt, F.9
Ali, M.E.10
Rogers, T.B.11
Lederer, W.J.12
Escande, D.13
Le Marec, H.14
Bennett, V.15
-
38
-
-
0035907032
-
Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome
-
Plaster N. M, R. Tawil, M. Tristani-Firouzi, S. Canun, S. Bendahhou, A. Tsunoda, M. R. Donaldson, S. T. Iannaccone, E. Brunt, R. Barohn, J. Clark, F. Deymeer, A. L. Jr. George, F. A. Fish, A. Hahn, A. Nitu, C. Ozdemir, P. Serdaroglu, S. H. Subramony, G. Wolfe, Y. H. Fu & L. J. Ptacek: Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome. Cell 105, 511-519 (2001)
-
(2001)
Cell
, vol.105
, pp. 511-519
-
-
Plaster, N.M.1
Tawil, R.2
Tristani-Firouzi, M.3
Canun, S.4
Bendahhou, S.5
Tsunoda, A.6
Donaldson, M.R.7
Iannaccone, S.T.8
Brunt, E.9
Barohn, R.10
Clark, J.11
Deymeer, F.12
George Jr., A.L.13
Fish, F.A.14
Hahn, A.15
Nitu, A.16
Ozdemir, C.17
Serdaroglu, P.18
Subramony, S.H.19
Wolfe, G.20
Fu, Y.H.21
Ptacek, L.J.22
more..
-
40
-
-
0037383482
-
Dominant-negative suppression of IKI in the mouse heart leads to altered cardiac excitability
-
McLerie M & A.N. Lopatin: Dominant-negative suppression of IKI in the mouse heart leads to altered cardiac excitability. J Mol Cell Cardiol 35, 367-378 (2003)
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 367-378
-
-
McLerie, M.1
Lopatin, A.N.2
-
42
-
-
0036789964
-
Kir6.2 is required for adaptation to stress
-
Zingman L. V, D. M. Hodgson, P. H. Bast, G. C. Kane, C. Perez-Terzic, R. J. Gumina, D. Pucar, M. Bienengraeber, P. P. Dzeja, T. Miki, S. Seino, A. E. Alekseev & A. Terzic: Kir6.2 is required for adaptation to stress. Proc Natl Acad Sci USA 99, 13278-13283 (2002)
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13278-13283
-
-
Zingman, L.V.1
Hodgson, D.M.2
Bast, P.H.3
Kane, G.C.4
Perez-Terzic, C.5
Gumina, R.J.6
Pucar, D.7
Bienengraeber, M.8
Dzeja, P.P.9
Miki, T.10
Seino, S.11
Alekseev, A.E.12
Terzic, A.13
-
43
-
-
5744226571
-
+ channel, predisposes to catecholamine-induced ventricular dysrhythmia
-
+ channel, predisposes to catecholamine-induced ventricular dysrhythmia. Diabetes 53 (Suppl 3), S165-S168 (2004)
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Liu, X.K.1
Yamada, S.2
Kane, G.C.3
Alekseev, A.E.4
Hodgson, D.M.5
O'Cochlain, F.6
Jahangir, A.7
Miki, T.8
Seino, S.9
Terzic, A.10
-
44
-
-
0036179325
-
Role of sarcolemmal KATP channels in cardioprotection against ischemia/reperfusion injury in mice
-
Suzuki M, N. Sasaki, T. Miki, N. Sakamoto, Y. Ohmoto-Sekine, M. Tamagawa, S. Seino, E. Marban & H. Nakaya: Role of sarcolemmal KATP channels in cardioprotection against ischemia/reperfusion injury in mice. J Clin Invest 109, 509-516 (2002)
-
(2002)
J Clin Invest
, vol.109
, pp. 509-516
-
-
Suzuki, M.1
Sasaki, N.2
Miki, T.3
Sakamoto, N.4
Ohmoto-Sekine, Y.5
Tamagawa, M.6
Seino, S.7
Marban, E.8
Nakaya, H.9
-
45
-
-
9244246342
-
The effect of vagally induced dispersion of action potential duration on atrial arrhythmogenesis
-
Vigmond E.J, V. Tsoi, S. Kuo, H. Arevalo, J. Kneller, S. Nattel & N. Trayanova The effect of vagally induced dispersion of action potential duration on atrial arrhythmogenesis. Heart Rhythm 1, 334-344 (2004)
-
(2004)
Heart Rhythm
, vol.1
, pp. 334-344
-
-
Vigmond, E.J.1
Tsoi, V.2
Kuo, S.3
Arevalo, H.4
Kneller, J.5
Nattel, S.6
Trayanova, N.7
-
46
-
-
0031909974
-
Abnormal heart rate regulation in GIRK4 knockout mice
-
Wickman K, J. Nemec, S. J. Gendler & D. E. Clapham: Abnormal heart rate regulation in GIRK4 knockout mice. Neuron 20, 103-114 (1998)
-
(1998)
Neuron
, vol.20
, pp. 103-114
-
-
Wickman, K.1
Nemec, J.2
Gendler, S.J.3
Clapham, D.E.4
-
47
-
-
0035876203
-
KACh atrial fibrillation using a mouse knockout model
-
KACh atrial fibrillation using a mouse knockout model. J Am Coll Cardiol 37, 2136-2143 (2001)
-
(2001)
J Am Coll Cardiol
, vol.37
, pp. 2136-2143
-
-
Kovoor, P.1
Wickman, K.2
Maguire, C.T.3
Pu, W.4
Gehrmann, J.5
Berul, C.I.6
Clapham, D.E.7
-
48
-
-
0032190435
-
Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice
-
Jumrussirikul P, J. Dinerman, T. M. Dawson, V. L. Dawson, U. Ekelund, D. Georgakopoulos, L. P. Schramm, H. Calkins, S. H. Snyder, J. M. Hare & R. D. Berger: Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice. J Clin Invest 102, 1279-1285 (1998)
-
(1998)
J Clin Invest
, vol.102
, pp. 1279-1285
-
-
Jumrussirikul, P.1
Dinerman, J.2
Dawson, T.M.3
Dawson, V.L.4
Ekelund, U.5
Georgakopoulos, D.6
Schramm, L.P.7
Calkins, H.8
Snyder, S.H.9
Hare, J.M.10
Berger, R.D.11
-
49
-
-
0036087868
-
Impaired parasympathetic heart rate control in transgenic mice with a reduction of functional G-protein β-subunits
-
Gehrmann J, M. Meister, C. T. Maguire, P. E. Hammer, E. J. Neer, C. I. Berul & U. Mende: Impaired parasympathetic heart rate control in transgenic mice with a reduction of functional G-protein β-subunits. Am J Physiol Heart Circ Physiol 282, H445-H456 (2002)
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
-
-
Gehrmann, J.1
Meister, M.2
Maguire, C.T.3
Hammer, P.E.4
Neer, E.J.5
Berul, C.I.6
Mende, U.7
-
50
-
-
16044368159
-
Decreased heart rate variability in transgenic mice overexpressing atrial β1adrenoceptors
-
Mansier P, C. Medigue, N. Charlotte, C. Vermeiren, E. Coraboeuf, E. Deroubaix, E. Ratner, B. Chevalier, J. Clairambault, F. Carre, T. Dahkli, B. Bertin, P. Briand, D. Strosberg & B. Swynghedauw: Decreased heart rate variability in transgenic mice overexpressing atrial β1adrenoceptors. Am J Physiol Heart Circ Physiol 271, H1465-H1472 (1996)
-
(1996)
Am J Physiol Heart Circ Physiol
, vol.271
-
-
Mansier, P.1
Medigue, C.2
Charlotte, N.3
Vermeiren, C.4
Coraboeuf, E.5
Deroubaix, E.6
Ratner, E.7
Chevalier, B.8
Clairambault, J.9
Carre, F.10
Dahkli, T.11
Bertin, B.12
Briand, P.13
Strosberg, D.14
Swynghedauw, B.15
-
51
-
-
0032498788
-
sα
-
sα. Circ Res 82, 416-423 (1998)
-
(1998)
Circ Res
, vol.82
, pp. 416-423
-
-
Uechi, M.1
Asai, K.2
Osaka, M.3
Smith, A.4
Sato, N.5
Wagner, T.E.6
Ishikawa, Y.7
Vatner, D.E.8
Shannon, R.P.9
Homey, C.J.10
Vatner, S.F.11
-
52
-
-
0038000737
-
Altered sinus nodal and atrioventricular nodal function in freely moving mice overexpressing the Al adenosine receptor
-
Kirchhof P, L. Fabritz, L. Fortmuller, G. P. Mathere, A. Lankford, H. A. Baba, W. Schmitz, G. Breithardt, J. Neumann & P. Boknik: Altered sinus nodal and atrioventricular nodal function in freely moving mice overexpressing the Al adenosine receptor. Am J Physiol Heart Circ Physiol 285, H145-H153 (2003)
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
-
-
Kirchhof, P.1
Fabritz, L.2
Fortmuller, L.3
Mathere, G.P.4
Lankford, A.5
Baba, H.A.6
Schmitz, W.7
Breithardt, G.8
Neumann, J.9
Boknik, P.10
-
53
-
-
0037178739
-
Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor
-
Black R.G. Jr, Y. Guo, Z. D. Ge, S. S. Murphree, S. D. Prabhu, W. K. Jones, R. Bolli & J. A. Auchampach: Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor. Circ 91, 165-172 (2002)
-
(2002)
Circ
, vol.91
, pp. 165-172
-
-
Black Jr, R.G.1
Guo, Y.2
Ge, Z.D.3
Murphree, S.S.4
Prabhu, S.D.5
Jones, W.K.6
Bolli, R.7
Auchampach, J.A.8
-
54
-
-
2442436385
-
Gene dose-dependent atrial arrhythmias, heart block, and brady-cardiomyopathy in mice overexpressing A(3) adenosine receptors
-
Fabritz L., P. Kirchhof, L. Fortmuller, J. A., Auchampach, H. A. Baba, G. Breithardt, J. Neumann, P. Boknik & W. Schmitz: Gene dose-dependent atrial arrhythmias, heart block, and brady-cardiomyopathy in mice overexpressing A(3) adenosine receptors. Cardiovasc Res 62, 500-508 (2004)
-
(2004)
Cardiovasc Res
, vol.62
, pp. 500-508
-
-
Fabritz, L.1
Kirchhof, P.2
Fortmuller, L.3
Auchampach, J.A.4
Baba, H.A.5
Breithardt, G.6
Neumann, J.7
Boknik, P.8
Schmitz, W.9
-
55
-
-
0034712586
-
Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy
-
Redfern C. H, M. Y. Degtyarev, A. T. Kwa, N. Salomonis, N. Cotte, T. Nanevicz, N. Fidelman, K. Desai, K. Vranizan, E. K. Lee, P. Coward, N. Shah, J. A. Warrington, G. I. Fishman, D- Bernstein, A. J. Baker & B. R. Conklin: Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy. Proc Natl Acad Sci USA91, 4826-4831 (2000)
-
(2000)
Proc Natl Acad Sci USA
, vol.91
, pp. 4826-4831
-
-
Redfern, C.H.1
Degtyarev, M.Y.2
Kwa, A.T.3
Salomonis, N.4
Cotte, N.5
Nanevicz, T.6
Fidelman, N.7
Desai, K.8
Vranizan, K.9
Lee, E.K.10
Coward, P.11
Shah, N.12
Warrington, J.A.13
Fishman, G.I.14
Bernstein, D.15
Baker, A.J.16
Conklin, B.R.17
-
56
-
-
0346687731
-
A & Ludwig: Pacemaker channels and sinus node arrhythmia
-
Stieber J, F. Hofmann, A & Ludwig: Pacemaker channels and sinus node arrhythmia. Trends Cardiovasc Med 14, 23-28 (2004)
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 23-28
-
-
Stieber, J.1
Hofmann, F.2
-
57
-
-
0037439203
-
Absence epilepsy and sinus dysrhythmia in mice lackkig the pacemaker channel HCN2
-
Ludwig A, T. Budde, J. Stieber, S. Moosmang, C. Wahl, K. Holthoff, A. Langebartels, C. Wotjak, T. Munsch, X. Zong, S. Feil, R. Feil, M. Lancel, K. R. Chien, A. Konnerth, H. C. Pape, M. Biel & F. Hofmann. Absence epilepsy and sinus dysrhythmia in mice lackkig the pacemaker channel HCN2. EMBO J22, 216-224 (2003)
-
(2003)
EMBO J
, vol.22
, pp. 216-224
-
-
Ludwig, A.1
Budde, T.2
Stieber, J.3
Moosmang, S.4
Wahl, C.5
Holthoff, K.6
Langebartels, A.7
Wotjak, C.8
Munsch, T.9
Zong, X.10
Feil, S.11
Feil, R.12
Lancel, M.13
Chien, K.R.14
Konnerth, A.15
Pape, H.C.16
Biel, M.17
Hofmann, F.18
-
58
-
-
0036293566
-
Predisposition to arrhythmia and autonomie dysfunction in Nhlhl-deficient mice
-
Cogliati T, D. J. Good, M. Haigney, P. DelgadoRomero, M. A. Eckhaus, W. J. Koch & I. R. Kirsch: Predisposition to arrhythmia and autonomie dysfunction in Nhlhl-deficient mice. Mol Cell Biol. 22,4977-4983 (2002)
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4977-4983
-
-
Cogliati, T.1
Good, D.J.2
Haigney, M.3
DelgadoRomero, P.4
Eckhaus, M.A.5
Koch, W.J.6
Kirsch, I.R.7
-
59
-
-
2342599742
-
Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression
-
Takeshita K, T. Fujimori, Y. Kurotaki, H. Honjo, H. Tsujikawa, K. Yasui, J. K. Lee, K. Kamiya, K. Kitaichi, K. Yamamoto, M. Ito, T. Kondo, S. lino, Y. Inden, M. Hirai, T. Murohara, I. Kodama & Y. Nabeshima: Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. Circulation 109, 1776-1782 (2004)
-
(2004)
Circulation
, vol.109
, pp. 1776-1782
-
-
Takeshita, K.1
Fujimori, T.2
Kurotaki, Y.3
Honjo, H.4
Tsujikawa, H.5
Yasui, K.6
Lee, J.K.7
Kamiya, K.8
Kitaichi, K.9
Yamamoto, K.10
Ito, M.11
Kondo, T.12
lino, S.13
Inden, Y.14
Hirai, M.15
Murohara, T.16
Kodama, I.17
Nabeshima, Y.18
-
60
-
-
0030636780
-
Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome
-
Basson C. T, D. R. Bachinsky, R. C. Lin, T. Levi, J. A. Elkins, J. Soults, D. Grayzel, E. Kroumpouzou, T. A. Traill, J. Leblanc-Straceski, B. Renault, R. Kucherlapati, J. G. Seidman & C. E. Seidman: Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nat Genet 15, 30-35 (1997)
-
(1997)
Nat Genet
, vol.15
, pp. 30-35
-
-
Basson, C.T.1
Bachinsky, D.R.2
Lin, R.C.3
Levi, T.4
Elkins, J.A.5
Soults, J.6
Grayzel, D.7
Kroumpouzou, E.8
Traill, T.A.9
Leblanc-Straceski, J.10
Renault, B.11
Kucherlapati, R.12
Seidman, J.G.13
Seidman, C.E.14
-
61
-
-
17944378083
-
A murine model of HoltOram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
-
Bruneau B. G, G. Nemer, J. P. Schmitt, F. Charron, L. Robitaille, S. Caron, D. A. Conner, M. Gessler, M. Nemer, C. E. Seidman & J. G. Seidman: A murine model of HoltOram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 106, 709-721 (2001)
-
(2001)
Cell
, vol.106
, pp. 709-721
-
-
Bruneau, B.G.1
Nemer, G.2
Schmitt, J.P.3
Charron, F.4
Robitaille, L.5
Caron, S.6
Conner, D.A.7
Gessler, M.8
Nemer, M.9
Seidman, C.E.10
Seidman, J.G.11
-
62
-
-
0032479573
-
Congenital heart disease caused by mutations in the transcription factor NKX2-5
-
Schott J. J, D. W. Benson, C. T. Basson, W. Pease, G. M. Silberbach, J. P. Moak, B. J. Maron, C. E. Seidman & J. G. Seidman: Congenital heart disease caused by mutations in the transcription factor NKX2-5. Science 281, 108-111 (1998)
-
(1998)
Science
, vol.281
, pp. 108-111
-
-
Schott, J.J.1
Benson, D.W.2
Basson, C.T.3
Pease, W.4
Silberbach, G.M.5
Moak, J.P.6
Maron, B.J.7
Seidman, C.E.8
Seidman, J.G.9
-
63
-
-
11144355678
-
Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system
-
Jay P. Y, B. S. Harris, C. T. Maguire, A. Buerger, H. Wakimoto, M. Tanaka, S- Kupershmidt, D. M. Roden, T. M. Schultheiss, T. X. O'Brien, R. G. Gourdie, C. I. Berul & S. Izumo: Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system. J Clin Invest 113, 1130-1137 (2004)
-
(2004)
J Clin Invest
, vol.113
, pp. 1130-1137
-
-
Jay, P.Y.1
Harris, B.S.2
Maguire, C.T.3
Buerger, A.4
Wakimoto, H.5
Tanaka, M.6
Kupershmidt, S.7
Roden, D.M.8
Schultheiss, T.M.9
O'Brien, T.X.10
Gourdie, R.G.11
Berul, C.I.12
Izumo, S.13
-
64
-
-
0034947445
-
Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein
-
Kasahara H, H. Wakimoto, M. Liu, C. T. Maguire, K. L. Converso, T. Shioi, W. Y. Huang, W. J. Manning, D. Paul, J. Lawitts, C. I. Berul & S. Izumo: Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein. J Clin Invest 108, 189-201 (2001)
-
(2001)
J Clin Invest
, vol.108
, pp. 189-201
-
-
Kasahara, H.1
Wakimoto, H.2
Liu, M.3
Maguire, C.T.4
Converso, K.L.5
Shioi, T.6
Huang, W.Y.7
Manning, W.J.8
Paul, D.9
Lawitts, J.10
Berul, C.I.11
Izumo, S.12
-
65
-
-
0035859215
-
Identification of a gene responsible for familial WolffParkinson-White syndrome
-
Gollob M. H, M. S. Green, A. S. Tang, T. Gollob, A. Karibe, A. S. Ali Hassan, F. Ahmad, R. Lozado, G. Shah, L. Fananapazir, L. L. Bachinski & R. Roberts: Identification of a gene responsible for familial WolffParkinson-White syndrome. N Engl J Med 344, 1823-1831 (2001)
-
(2001)
N Engl J Med
, vol.344
, pp. 1823-1831
-
-
Gollob, M.H.1
Green, M.S.2
Tang, A.S.3
Gollob, T.4
Karibe, A.5
Ali Hassan, A.S.6
Ahmad, F.7
Lozado, R.8
Shah, G.9
Fananapazir, L.10
Bachinski, L.L.11
Roberts, R.12
-
66
-
-
0036167225
-
Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophie cardiomyopathy
-
Arad M, D. W. Benson, A. R. Perez-Atayde, W. J. McKenna, E. A. Sparks, R. J. Kanter, K. McGarr, J. G. Seidman & C. E. Seidman. Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophie cardiomyopathy. J Clin Invest 109, 357-362 (2002)
-
(2002)
J Clin Invest
, vol.109
, pp. 357-362
-
-
Arad, M.1
Benson, D.W.2
Perez-Atayde, A.R.3
McKenna, W.J.4
Sparks, E.A.5
Kanter, R.J.6
McGarr, K.7
Seidman, J.G.8
Seidman, C.E.9
-
67
-
-
0042364977
-
Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome
-
Patel V. V, M. Arad, I. P. Moskowitz, C. T. Maguire, D. Branco, J. G. Seidman, C. E. Seidman & C. I. Berul: Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome. J Am Coll Cardiol 42, 942-951 (2003)
-
(2003)
J Am Coll Cardiol
, vol.42
, pp. 942-951
-
-
Patel, V.V.1
Arad, M.2
Moskowitz, I.P.3
Maguire, C.T.4
Branco, D.5
Seidman, J.G.6
Seidman, C.E.7
Berul, C.I.8
-
68
-
-
0037782349
-
Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy
-
Arad M, I. P. Moskowitz, V. V. Patel, F. Ahmad, A. R. Perez-Atayde, D. B. Sawyer, M. Walter, G. H. Li, P. G. Burgon, C. T. Maguire, D. Stapleton, J. P. Schmitt, X. X. Guo, A. Pizard, S. Kupershmidt, D. M. Roden, C. I. Berul, C. E. Seidman & J. G. Seidman: Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy. Circulation 107, 2850-2856 (2003)
-
(2003)
Circulation
, vol.107
, pp. 2850-2856
-
-
Arad, M.1
Moskowitz, I.P.2
Patel, V.V.3
Ahmad, F.4
Perez-Atayde, A.R.5
Sawyer, D.B.6
Walter, M.7
Li, G.H.8
Burgon, P.G.9
Maguire, C.T.10
Stapleton, D.11
Schmitt, J.P.12
Guo, X.X.13
Pizard, A.14
Kupershmidt, S.15
Roden, D.M.16
Berul, C.I.17
Seidman, C.E.18
Seidman, J.G.19
-
69
-
-
19944429566
-
Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-ParkinsonWhite syndrome
-
Sidhu J. S, Y. S. Rajawat, T. G. Rami, M. H. Gollob, Z. Wang, R. Yuan, A. J. Marian, F. J. DeMayo, D. Weilbacher, G. E. Taffet, J. K. Davies, D. Carling, D. S. Khoury & R. Roberts: Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-ParkinsonWhite syndrome. Circulation 111, 21-29 (2005)
-
(2005)
Circulation
, vol.111
, pp. 21-29
-
-
Sidhu, J.S.1
Rajawat, Y.S.2
Rami, T.G.3
Gollob, M.H.4
Wang, Z.5
Yuan, R.6
Marian, A.J.7
DeMayo, F.J.8
Weilbacher, D.9
Taffet, G.E.10
Davies, J.K.11
Carling, D.12
Khoury, D.S.13
Roberts, R.14
-
70
-
-
0034264850
-
A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages
-
Nguyen-Tran V. T, S. W. Kubalak, S. Minamisawa, C. Fiset, K. C. Wollert, A. B. Brown, P. Ruiz-Lozano, S. Barrere-Lemaire, R. Kondo, L. W. Norman, R. G. Gourdie, M. M. Rahme, G. K. Feld, R. B. Clark, W. R. Giles & K. R. Chien: A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages. Cell 10, 671-682 (2000)
-
(2000)
Cell
, vol.10
, pp. 671-682
-
-
Nguyen-Tran, V.T.1
Kubalak, S.W.2
Minamisawa, S.3
Fiset, C.4
Wollert, K.C.5
Brown, A.B.6
Ruiz-Lozano, P.7
Barrere-Lemaire, S.8
Kondo, R.9
Norman, L.W.10
Gourdie, R.G.11
Rahme, M.M.12
Feld, G.K.13
Clark, R.B.14
Giles, W.R.15
Chien, K.R.16
-
71
-
-
3242772173
-
Calcium cycling proteins in heart failure, cardiomyopathy and arrhythmias
-
Minamisawa S, Y. Sato & M. C. Cho: Calcium cycling proteins in heart failure, cardiomyopathy and arrhythmias. Exp Mol Med 36, 193-203 (2004)
-
(2004)
Exp Mol Med
, vol.36
, pp. 193-203
-
-
Minamisawa, S.1
Sato, Y.2
Cho, M.C.3
-
72
-
-
0037015257
-
Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy
-
Wu Y, J. Temple, R. Zhang, I. Dzhura, W. Zhang, R. Trimble, D. M. Roden, R. Passier, E. N. Olson, R. J. Colbran & M. E. Anderson: Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation 106, 1288-1293 (2002)
-
(2002)
Circulation
, vol.106
, pp. 1288-1293
-
-
Wu, Y.1
Temple, J.2
Zhang, R.3
Dzhura, I.4
Zhang, W.5
Trimble, R.6
Roden, D.M.7
Passier, R.8
Olson, E.N.9
Colbran, R.J.10
Anderson, M.E.11
-
73
-
-
21144446266
-
Calmodulin kinase II activity is required for normal atrioventricular nodal conduction
-
Khoo M.S, P. J. Kannankeril, J. Li, R. Zhang, S. Kupershmidt, W. Zhang, J. B. Atkinson, R. J. Colbran, D. M. Roden & M. E. Anderson: Calmodulin kinase II activity is required for normal atrioventricular nodal conduction. Heart Rhythm 2, 634-640 (2005)
-
(2005)
Heart Rhythm
, vol.2
, pp. 634-640
-
-
Khoo, M.S.1
Kannankeril, P.J.2
Li, J.3
Zhang, R.4
Kupershmidt, S.5
Zhang, W.6
Atkinson, J.B.7
Colbran, R.J.8
Roden, D.M.9
Anderson, M.E.10
-
74
-
-
0035253502
-
Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2)
-
Tiso N, D. A. Stephan, A. Nava, A. Bagattin, J. M. Devaney, F. Stanchi, G. Larderet, B. Brahmbhatt, K. Brown, B. Bauce, M. Muriago, C. Basso, G. Thiene, G. A. Danieli & A. Rampazzo: Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2). Hum Mol Genet 10, 189-194 (2001)
-
(2001)
Hum Mol Genet
, vol.10
, pp. 189-194
-
-
Tiso, N.1
Stephan, D.A.2
Nava, A.3
Bagattin, A.4
Devaney, J.M.5
Stanchi, F.6
Larderet, G.7
Brahmbhatt, B.8
Brown, K.9
Bauce, B.10
Muriago, M.11
Basso, C.12
Thiene, G.13
Danieli, G.A.14
Rampazzo, A.15
-
75
-
-
0035895322
-
Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia
-
Priori S. G, C. Napolitano, N. Tiso, M. Memmi, G. Vignati, R. Bloise, V. Sorrentino & G. A. Danieli: Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia. Circulation 103, 196-200 (2001)
-
(2001)
Circulation
, vol.103
, pp. 196-200
-
-
Priori, S.G.1
Napolitano, C.2
Tiso, N.3
Memmi, M.4
Vignati, G.5
Bloise, R.6
Sorrentino, V.7
Danieli, G.A.8
-
76
-
-
0037131020
-
Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia
-
Postma A. V, I. Denjoy, T. M. Hoorntje, J. M. Lupoglazoff, A. Da Costa, P. Sebillon, M. M. Mannens, A. A. Wilde & P. Guicheney: Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia. Circ Res 91, e21-e26 (2002)
-
(2002)
Circ Res
, vol.91
-
-
Postma, A.V.1
Denjoy, I.2
Hoorntje, T.M.3
Lupoglazoff, J.M.4
Da Costa, A.5
Sebillon, P.6
Mannens, M.M.7
Wilde, A.A.8
Guicheney, P.9
-
77
-
-
0037708928
-
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
-
Wehrens X. H, S. E. Lehnart, F. Huang, J. A. Vest, S. R. Reiken, P. J. Mohler, J. Sun, S. Guatimosim, L. S. Song, N. Rosemblit, J. M. D'Armiento, C. Napolitano, M. Memmi, S. G. Priori, W. J. Lederer & A. R. Marks. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell 113, 829-840 (2003)
-
(2003)
Cell
, vol.113
, pp. 829-840
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Huang, F.3
Vest, J.A.4
Reiken, S.R.5
Mohler, P.J.6
Sun, J.7
Guatimosim, S.8
Song, L.S.9
Rosemblit, N.10
D'Armiento, J.M.11
Napolitano, C.12
Memmi, M.13
Priori, S.G.14
Lederer, W.J.15
Marks, A.R.16
-
78
-
-
1842482414
-
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2
-
Wehrens X.H, S. E. Lehnart, S. R. Reiken, S. X. Deng, J. A. Vest, D. Cervantes, J. Coromilas, D. W. Landry & A. R. Marks: Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2. Science 304, 292-296 (2004)
-
(2004)
Science
, vol.304
, pp. 292-296
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Reiken, S.R.3
Deng, S.X.4
Vest, J.A.5
Cervantes, D.6
Coromilas, J.7
Landry, D.W.8
Marks, A.R.9
-
79
-
-
0037304454
-
+ channels
-
+ channels. Cardiovasc Res 57, 320-332 (2003)
-
(2003)
Cardiovasc Res
, vol.57
, pp. 320-332
-
-
Dong, D.1
Duan, Y.2
Guo, J.3
Roach, D.E.4
Swirp, S.L.5
Wang, L.6
Lees-Miller, J.P.7
Sheldon, R.S.8
Molkentin, J.D.9
Duff, H.J.10
-
80
-
-
8644278031
-
Heart block in mice overexpressing calcineurin but not NF-AT3
-
Gillis A. M, K. M. Kavanagh, H. J. Mathison, J. R. Somers, S. Zhan & H. J. Duff: Heart block in mice overexpressing calcineurin but not NF-AT3. Cardiovasc Res 64, 488-495 (2004)
-
(2004)
Cardiovasc Res
, vol.64
, pp. 488-495
-
-
Gillis, A.M.1
Kavanagh, K.M.2
Mathison, H.J.3
Somers, J.R.4
Zhan, S.5
Duff, H.J.6
-
81
-
-
0036674423
-
Cardiac remodeling and atrial fibrillation in transgenic mice overexpressing junctin
-
Hong C. S, M. C. Cho, Y. G. Kwak, C. H. Song, Y. H. Lee, J. S. Lim, Y. K. Kwon, S. W. Chae & H. do Kim: Cardiac remodeling and atrial fibrillation in transgenic mice overexpressing junctin. FASEB J 16, 1310-1312 (2002)
-
(2002)
FASEB J
, vol.16
, pp. 1310-1312
-
-
Hong, C.S.1
Cho, M.C.2
Kwak, Y.G.3
Song, C.H.4
Lee, Y.H.5
Lim, J.S.6
Kwon, Y.K.7
Chae, S.W.8
do Kim, H.9
-
82
-
-
0035011351
-
Complete heart block and sudden death in mice overexpressing calreticulin
-
Nakamura K, M. Robertson, G. Liu, P. Dickie, K. Nakamura, J. Q. Guo, H. J. Duff, M. Opas, K. Kavanagh & M. Michalak: Complete heart block and sudden death in mice overexpressing calreticulin. J Clin Invest 107, 1245-1253 (2001)
-
(2001)
J Clin Invest
, vol.107
, pp. 1245-1253
-
-
Nakamura, K.1
Robertson, M.2
Liu, G.3
Dickie, P.4
Nakamura, K.5
Guo, J.Q.6
Duff, H.J.7
Opas, M.8
Kavanagh, K.9
Michalak, M.10
-
83
-
-
0030763808
-
Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factoralpha
-
Kubota T, C. F. McTiernan, C. S. Frye, S. E. Slawson, B. H. Lemster, A. P. Koretsky, A. J. Demetris & A. M. Feldman: Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factoralpha. Circ Res 81, 627-635 (1997)
-
(1997)
Circ Res
, vol.81
, pp. 627-635
-
-
Kubota, T.1
McTiernan, C.F.2
Frye, C.S.3
Slawson, S.E.4
Lemster, B.H.5
Koretsky, A.P.6
Demetris, A.J.7
Feldman, A.M.8
-
84
-
-
0037305207
-
Calcium-dependent arrhythmias in transgenic mice with heart failure
-
London B, L. C. Baker, J. S. Lee, V. Shusterman, B. R. Choi, T. Kubota, C. F. McTiernan, A. M. Feldman & G. Salama: Calcium-dependent arrhythmias in transgenic mice with heart failure. Am J Physiol Heart Circ Physiol 284, H431-H441 (2003)
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
London, B.1
Baker, L.C.2
Lee, J.S.3
Shusterman, V.4
Choi, B.R.5
Kubota, T.6
McTiernan, C.F.7
Feldman, A.M.8
Salama, G.9
-
85
-
-
14644435170
-
Angiotensin II, angiotensin II antagonists and spironolactone and their modulation of cardiac repolarization
-
Delpón E, R. Caballero, R. Gómez, L. Núñez & J. Tamargo: Angiotensin II, angiotensin II antagonists and spironolactone and their modulation of cardiac repolarization. Trends Pharmacol Sci 26, 155-161 (2005)
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 155-161
-
-
Delpón, E.1
Caballero, R.2
Gómez, R.3
Núñez, L.4
Tamargo, J.5
-
86
-
-
0030610246
-
Overexpression of angiotensin ATI receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block
-
Hein L, M. E. Stevens, G. S. Barsh, R. E. Pratt, B. K. Kobilka & V. J. Dzau: Overexpression of angiotensin ATI receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block. Proc Natl Acad Sci USA 94, 6391-6396 (1997)
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6391-6396
-
-
Hein, L.1
Stevens, M.E.2
Barsh, G.S.3
Pratt, R.E.4
Kobilka, B.K.5
Dzau, V.J.6
-
87
-
-
27644468385
-
Cardiac-specific overexpression of ATI receptor mutant lacking Gαq/Gαi coupling causes hypertrophy and bradycardia in transgenic mice
-
Zhai P, M. Yamamoto, J. Galeotti, J. Liu, M. Masurekar, J. Thaisz, K. Irie, E. Holle, X. Xu, S. Kupershmidt, D. M. Roden, T. Wagner, A. Yatani, D. E. Vatner, S. F. Vatner & J. Sadoshima: Cardiac-specific overexpression of ATI receptor mutant lacking Gαq/Gαi coupling causes hypertrophy and bradycardia in transgenic mice. J Clin Invest 115, 3045-3056 (2005)
-
(2005)
J Clin Invest
, vol.115
, pp. 3045-3056
-
-
Zhai, P.1
Yamamoto, M.2
Galeotti, J.3
Liu, J.4
Masurekar, M.5
Thaisz, J.6
Irie, K.7
Holle, E.8
Xu, X.9
Kupershmidt, S.10
Roden, D.M.11
Wagner, T.12
Yatani, A.13
Vatner, D.E.14
Vatner, S.F.15
Sadoshima, J.16
-
88
-
-
12144288194
-
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
-
Caron K. M, L. R. James, H. S. Kim, J. Knowles, R. Uhlir, L. Mao, J. R. Hagaman, W. Cascio, H. Rockman & O. Smithies: Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene. Proc Natl Acad Sci U S A 101, 3106-3111 (2004)
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3106-3111
-
-
Caron, K.M.1
James, L.R.2
Kim, H.S.3
Knowles, J.4
Uhlir, R.5
Mao, L.6
Hagaman, J.R.7
Cascio, W.8
Rockman, H.9
Smithies, O.10
-
89
-
-
0030964665
-
Renin-angiotensin system: Genes to bedside
-
Malik F. S, C. J. Lavie, M. R. Mehra, R. V. Milani & R. N. Re: Renin-angiotensin system: genes to bedside. Am Heart J 134, 514-526 (1997)
-
(1997)
Am Heart J
, vol.134
, pp. 514-526
-
-
Malik, F.S.1
Lavie, C.J.2
Mehra, M.R.3
Milani, R.V.4
Re, R.N.5
-
90
-
-
4344600627
-
Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death
-
Xiao H. D, S. Fuchs, D. J. Campbell, W. Lewis, S. C. Jr. Dudley, V. S. Kasi, B. D. Hoit, G. Keshelava, H. Zhao, M. R. Capecchi & K. E. Bernstein: Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. Am J Pathol 165, 1019-1032 (2004)
-
(2004)
Am J Pathol
, vol.165
, pp. 1019-1032
-
-
Xiao, H.D.1
Fuchs, S.2
Campbell, D.J.3
Lewis, W.4
Dudley Jr., S.C.5
Kasi, V.S.6
Hoit, B.D.7
Keshelava, G.8
Zhao, H.9
Capecchi, M.R.10
Bernstein, K.E.11
-
91
-
-
10744223104
-
Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins
-
Donoghue M, H. Wakimoto, C. T. Maguire, S. Acton, P. Hales, N. Stagliano, V. Fairchild-Huntress, J. Xu, J. N. Lorenz, V. Kadambi, C. I. Berul & R. E. Breitbart: Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J Mol Cell Cardiol 35, 1043-1053 (2003)
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 1043-1053
-
-
Donoghue, M.1
Wakimoto, H.2
Maguire, C.T.3
Acton, S.4
Hales, P.5
Stagliano, N.6
Fairchild-Huntress, V.7
Xu, J.8
Lorenz, J.N.9
Kadambi, V.10
Berul, C.I.11
Breitbart, R.E.12
-
92
-
-
20544464438
-
Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias
-
Ouvrard-Pascaud A, Y. Sainte-Marie, J. P. Benitah, R. Perrier, C. Soukaseum, A. N. Cat, A. Royer, K. Le Quang, F. Charpentier, S. Demolombe, F. Mechta-Grigoriou, A. T. Beggah, P. Maison-Blanche, M. E. Oblin, C. Delcayre, G. I. Fishman, N. Farman, B. Escoubet & F. Jaisser: Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias. Circulation 111, 3025-3033 (2005)
-
(2005)
Circulation
, vol.111
, pp. 3025-3033
-
-
Ouvrard-Pascaud, A.1
Sainte-Marie, Y.2
Benitah, J.P.3
Perrier, R.4
Soukaseum, C.5
Cat, A.N.6
Royer, A.7
Le Quang, K.8
Charpentier, F.9
Demolombe, S.10
Mechta-Grigoriou, F.11
Beggah, A.T.12
Maison-Blanche, P.13
Oblin, M.E.14
Delcayre, C.15
Fishman, G.I.16
Farman, N.17
Escoubet, B.18
Jaisser, F.19
-
93
-
-
0031030298
-
Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophie cardiomyopathy mice
-
Berul C.I., M. E. Christe, M. J. Aronovitz, C. E. Seidman, J. G. Seidman & M. E. Mendelsohn: Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophie cardiomyopathy mice. J Clin Invest 99, 570-576 (1997)
-
(1997)
J Clin Invest
, vol.99
, pp. 570-576
-
-
Berul, C.I.1
Christe, M.E.2
Aronovitz, M.J.3
Seidman, C.E.4
Seidman, J.G.5
Mendelsohn, M.E.6
-
94
-
-
0035960590
-
CE & J.G. Seidman: Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene
-
Berul C. I., M. B.K. McConnell, H. Wakimoto, I. P. Moskowitz, C. T. Semsarian, M. M. Vargas, J. Gehrmann, C. E. Seidman CE & J.G. Seidman: Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene. Circulation 104, 2734-2739 (2001)
-
(2001)
Circulation
, vol.104
, pp. 2734-2739
-
-
Berul, C.I.1
McConnell, M.B.K.2
Wakimoto, H.3
Moskowitz, I.P.4
Semsarian, C.T.5
Vargas, M.M.6
Gehrmann, J.7
Seidman, C.E.8
-
95
-
-
0033518282
-
Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease
-
Fatkin D, C. MacRae, T. Sasaki, M. R. Wolff, M. Porcu, M. Frenneaux, J. Atherton, H. J. Jr. Vidaillet, S. Spudich, U. de Girolami, J. G. Seidman, C. E. Seidman, F. Muntoni, G. Muehle, W. Johnson & B. McDonough: Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. N Engl J Med. 341, 1715-1724 (1999)
-
(1999)
N Engl J Med
, vol.341
, pp. 1715-1724
-
-
Fatkin, D.1
MacRae, C.2
Sasaki, T.3
Wolff, M.R.4
Porcu, M.5
Frenneaux, M.6
Atherton, J.7
Vidaillet Jr., H.J.8
Spudich, S.9
de Girolami, U.10
Seidman, J.G.11
Seidman, C.E.12
Muntoni, F.13
Muehle, G.14
Johnson, W.15
McDonough, B.16
-
96
-
-
19944426537
-
Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies
-
Arimura T, A. Heilbling-Leclerc, C. Massart, S. Vamous, F. Niel, E. Lacene, Y. Fromes, M. Toussaint, A. M. Mura, D. I. Keller, H. Amthor, R. Isnard, M. Malissen, K. Schwartz & G. Bonne: Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies. Hum Mol Genet 14, 155-169 (2005)
-
(2005)
Hum Mol Genet
, vol.14
, pp. 155-169
-
-
Arimura, T.1
Heilbling-Leclerc, A.2
Massart, C.3
Vamous, S.4
Niel, F.5
Lacene, E.6
Fromes, Y.7
Toussaint, M.8
Mura, A.M.9
Keller, D.I.10
Amthor, H.11
Isnard, R.12
Malissen, M.13
Schwartz, K.14
Bonne, G.15
-
97
-
-
2942689981
-
-
Verheule S, T. Sato, T. 4th. Everett, S. K. Engle, D. Otten, M. Rubart-von der Lohe, H. O. Nakajima, L. J. Field & J. E. Olgin: Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1. Circ Res 94, 1458-1465 (2004)
-
Verheule S, T. Sato, T. 4th. Everett, S. K. Engle, D. Otten, M. Rubart-von der Lohe, H. O. Nakajima, L. J. Field & J. E. Olgin: Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1. Circ Res 94, 1458-1465 (2004)
-
-
-
-
98
-
-
20044376864
-
Heart-directed expression of a human cardiac isoform of cAMP-response element modulator in transgenic mice
-
Muller F. U, G. Lewin, H. A. Baba, P. Boknik, L. Fabritz, U. Kirchhefer, P. Kirchhof, K. Loser, M. Malus, J. Neumann, B. Riemann & W. Schmitz: Heart-directed expression of a human cardiac isoform of cAMP-response element modulator in transgenic mice. J Biol Chem 280, 6906-6914 (2005)
-
(2005)
J Biol Chem
, vol.280
, pp. 6906-6914
-
-
Muller, F.U.1
Lewin, G.2
Baba, H.A.3
Boknik, P.4
Fabritz, L.5
Kirchhefer, U.6
Kirchhof, P.7
Loser, K.8
Malus, M.9
Neumann, J.10
Riemann, B.11
Schmitz, W.12
-
99
-
-
1942502918
-
Genetically modified mice: Tools to decode the functions of connexins in the heart-new models for cardiovascular research
-
Gros D, L. Dupays, S Alcolea, S. Meysen, L. Miquerol & M. Theveniau-Ruissy: Genetically modified mice: tools to decode the functions of connexins in the heart-new models for cardiovascular research. Cardiovasc Res 62, 299-308 (2004)
-
(2004)
Cardiovasc Res
, vol.62
, pp. 299-308
-
-
Gros, D.1
Dupays, L.2
Alcolea, S.3
Meysen, S.4
Miquerol, L.5
Theveniau-Ruissy, M.6
-
100
-
-
0032567957
-
Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice
-
Kirchhoff S, E. Nelles, A. Hagendorff, O. Kruger, O. Traub & K. Willecke: Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr Biol 8, 299-302 (1998)
-
(1998)
Curr Biol
, vol.8
, pp. 299-302
-
-
Kirchhoff, S.1
Nelles, E.2
Hagendorff, A.3
Kruger, O.4
Traub, O.5
Willecke, K.6
-
101
-
-
0033756670
-
-
VanderBrink B.A, C. Sellito, C. Saba, M. S. Link, W. Zhu, M. K. Homoud, N. A. 3rd. Estes, D. L. Paul & P. J. Wang: Connexin40-deficient mice exhibit atrioventricular nodal and infra-Hisian conduction abnormalities. J. Cardiovasc Electrophysiol 11, 1270-1276 (2000)
-
VanderBrink B.A, C. Sellito, C. Saba, M. S. Link, W. Zhu, M. K. Homoud, N. A. 3rd. Estes, D. L. Paul & P. J. Wang: Connexin40-deficient mice exhibit atrioventricular nodal and infra-Hisian conduction abnormalities. J. Cardiovasc Electrophysiol 11, 1270-1276 (2000)
-
-
-
-
102
-
-
0033824984
-
Loss of connexin45 causes a cushion defect in early cardiogenesis
-
Kumai M, K. Nishii, K. Nakamura, N. Takeda, M. Suzuki & Y. Shibata: Loss of connexin45 causes a cushion defect in early cardiogenesis. Development 127, 3501-3512 (2000)
-
(2000)
Development
, vol.127
, pp. 3501-3512
-
-
Kumai, M.1
Nishii, K.2
Nakamura, K.3
Takeda, N.4
Suzuki, M.5
Shibata, Y.6
-
103
-
-
0035895649
-
Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43
-
Gutstein D. E, G. E. Morley, H. Tamaddon, D. Vaidya, M. D. Schneider, J. Chen, K. R. Chien, H. Stuhlmann & G. I. Fishman: Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43. Circ Res 88, 333-339 (2001)
-
(2001)
Circ Res
, vol.88
, pp. 333-339
-
-
Gutstein, D.E.1
Morley, G.E.2
Tamaddon, H.3
Vaidya, D.4
Schneider, M.D.5
Chen, J.6
Chien, K.R.7
Stuhlmann, H.8
Fishman, G.I.9
-
104
-
-
0035806899
-
Heterogeneous expression of Gap junction channels in the heart leads to conduction defects and ventricular dysfunction
-
Gutstein D. E, G. E. Morley, D. Vaidya, F. Liu, F. L. Chen, H. Stuhlmann & G. I. Fishman: Heterogeneous expression of Gap junction channels in the heart leads to conduction defects and ventricular dysfunction. Circulation 104, 1194-1199 (2001)
-
(2001)
Circulation
, vol.104
, pp. 1194-1199
-
-
Gutstein, D.E.1
Morley, G.E.2
Vaidya, D.3
Liu, F.4
Chen, F.L.5
Stuhlmann, H.6
Fishman, G.I.7
-
106
-
-
0030983063
-
Slow ventricular conduction in mice heterozygous for a connexin43 null mutation
-
Guerrero P. A, R. B. Schuessler, L. M. Davis, E. C. Beyer, C. M. Johnson, K. A. Yamada & J. E. Saffitz: Slow ventricular conduction in mice heterozygous for a connexin43 null mutation. J Clin Invest 99, 1991-1998 (1997)
-
(1997)
J Clin Invest
, vol.99
, pp. 1991-1998
-
-
Guerrero, P.A.1
Schuessler, R.B.2
Davis, L.M.3
Beyer, E.C.4
Johnson, C.M.5
Yamada, K.A.6
Saffitz, J.E.7
-
107
-
-
0034620495
-
Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice
-
Lerner D. L, K. A. Yamada, R. B. Schuessler & J. E. Saffitz: Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice. Circulation 101, 547-552 (2000)
-
(2000)
Circulation
, vol.101
, pp. 547-552
-
-
Lerner, D.L.1
Yamada, K.A.2
Schuessler, R.B.3
Saffitz, J.E.4
-
108
-
-
1442359119
-
Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43
-
Van Rijen H. V, D. Eckardt, J. Degen, M. Theis, T. Ott, K. Willecke, H. J. Jongsma, T. Opthof & J. M. de Bakker: Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43. Circulation 109, 1048-1055 (2004)
-
(2004)
Circulation
, vol.109
, pp. 1048-1055
-
-
Van Rijen, H.V.1
Eckardt, D.2
Degen, J.3
Theis, M.4
Ott, T.5
Willecke, K.6
Jongsma, H.J.7
Opthof, T.8
de Bakker, J.M.9
-
109
-
-
8844286738
-
Modulation of cardiac gap junction expression and arrhythmic susceptibility
-
Danik S. B, F. Liu, J. Zhang, H. J. Suk, G. E. Morle, G. I. Fishman & D. E. Gutstein: Modulation of cardiac gap junction expression and arrhythmic susceptibility. Circ Res 95, 1035-1041 (2004)
-
(2004)
Circ Res
, vol.95
, pp. 1035-1041
-
-
Danik, S.B.1
Liu, F.2
Zhang, J.3
Suk, H.J.4
Morle, G.E.5
Fishman, G.I.6
Gutstein, D.E.7
-
110
-
-
15244353801
-
Reduced intercellular coupling leads to paradoxical propagation across the Purkinje-ventricular junction and aberrant myocardial activation
-
Morley G. E, S. B. Danik, S. Bernstein, Y. Sun, G. Rosner, D. E. Gutstein & G. I. Fishman: Reduced intercellular coupling leads to paradoxical propagation across the Purkinje-ventricular junction and aberrant myocardial activation. Proc Natl Acad Sci USA 102, 4126-4129 (2005)
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4126-4129
-
-
Morley, G.E.1
Danik, S.B.2
Bernstein, S.3
Sun, Y.4
Rosner, G.5
Gutstein, D.E.6
Fishman, G.I.7
-
111
-
-
22744436379
-
Focal gap junction uncoupling and spontaneous ventricular ectopy
-
Gutstein D. E, S. B. Danik, S. Lewitton, D. France, F. Liu, F. L. Chen, J. Zhang N. Ghodsi, G. E. Morley & G. I. Fishman: Focal gap junction uncoupling and spontaneous ventricular ectopy. Am J Physiol Circ Physiol 289, HI091-HI098 (2005)
-
(2005)
Am J Physiol Circ Physiol
, vol.289
-
-
Gutstein, D.E.1
Danik, S.B.2
Lewitton, S.3
France, D.4
Liu, F.5
Chen, F.L.6
Zhang, J.7
Ghodsi, N.8
Morley, G.E.9
Fishman, G.I.10
-
112
-
-
14044256554
-
Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure
-
Kostetskii I, J. Li, Y. Xiong, R. Zhou, V. A. Ferrari, V. V. Patel, J. D. Molkentin & G. L. Radice: Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circ Res 96, 346-354 (2005)
-
(2005)
Circ Res
, vol.96
, pp. 346-354
-
-
Kostetskii, I.1
Li, J.2
Xiong, Y.3
Zhou, R.4
Ferrari, V.A.5
Patel, V.V.6
Molkentin, J.D.7
Radice, G.L.8
-
113
-
-
24744444972
-
Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis
-
Li J, V. V. Patel, I. Kostetskii, Y. Xiong, A. F. Chu, J. T. Jacobson, C. Yu, G. E. Morley, J. D. Molkentin & G. L. Radice: Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis. Circ Res 97, 474-481 (2005)
-
(2005)
Circ Res
, vol.97
, pp. 474-481
-
-
Li, J.1
Patel, V.V.2
Kostetskii, I.3
Xiong, Y.4
Chu, A.F.5
Jacobson, J.T.6
Yu, C.7
Morley, G.E.8
Molkentin, J.D.9
Radice, G.L.10
-
114
-
-
20844463585
-
Transcription enhancer factor-1-related factor-transgenic mice develop cardiac conduction defects associated with altered connexin phosphorylation
-
Chen H. H, C. J. Baty, T. Maeda, S. Brooks, L. C. Baker, T. Ueyama, E. Gursoy, S. Saba, G. Salama, B. London & A. F. Stewart: Transcription enhancer factor-1-related factor-transgenic mice develop cardiac conduction defects associated with altered connexin phosphorylation. Circulation 110, 2980-2987 (2004)
-
(2004)
Circulation
, vol.110
, pp. 2980-2987
-
-
Chen, H.H.1
Baty, C.J.2
Maeda, T.3
Brooks, S.4
Baker, L.C.5
Ueyama, T.6
Gursoy, E.7
Saba, S.8
Salama, G.9
London, B.10
Stewart, A.F.11
|