Renin-angiotensin system: Genes to bedside

American Heart Journal

Volumn 134, Issue 3, 1997, Pages 514-526

  Malik, F S ^a   Lavie, C J ^a   Mehra, M R ^a   Milani, R V ^a   Re, R N ^a  

^a OCHSNER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ANGIOTENSIN; DIPEPTIDYL CARBOXYPEPTIDASE; RENIN;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ENZYME POLYMORPHISM; HUMAN; NONHUMAN; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RESTENOSIS;

EID: 0030964665     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-8703(97)70089-9     Document Type: Article

References (81)

1. WB. Kannel Bishop lecture. Contribution of the Framingham Study to preventive cardiology J Am Coll Cardiol 15 1990 206 211
2. MA Pfeffer E Braunwald LA Moye L Basta EJ Brown Jr TE Cuddy Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after acute myocardial infarction. Result of the survival and ventricular enlargement trial The SAVE Investigators N Engl J Med 327 1992 669 677
3. S Yusuf CJ Pepine C Graces H Pouleur D Salem J Kostis Effects of enalapril on myocardial infarction and unstable angina in patients with low ejection fraction Lancet 340 1992 1173 1178
4. The SOLVD investigators Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions N Engl J Med 327 1992 685 691
5. P Hilbert K Lindpaintner JS Beckmann T Serikawa F Soubrier C Dubav Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats Nature 353 1991 521 529
6. MG Mattei C Hubert F Alhenc-Gelas N Roeckel P Corvol F. Soubrier Angiotensin I converting enzyme gene is on chromosome 17 Cytogenet Cell Genet 51 1989 1041 1045
7. L Tiret B Rigat S Visvikis Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels Am J Hum Genet 51 1992 197 205
8. B Rigat C Hubert P Corvol F. Soubrier PCR detection of the insertion/deletion polymorphism of the human angiotensin-converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1) Nucleic Acids Res 20 1992 1433
9. F Cambien F Alhenc-Gelas B Herbeth Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy study Am J Hum Genet 43 1988 774 780
10. B Rigat C Hubert F Alhenc-Gelas F Cambien P Corvol F. Soubrier An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels J Clin Invest 86 1990 1343 1346
11. VJ Dzau R. Re Tissue angiotensin system in cardiovascular medicine. A paradigm shift? Circulation 89 1 1994 493 498
12. H Urata B Healy RW Stewart FM Bumpus A. Husain Angiotensin II-forming pathways in normal and failing human hearts Circ Res 66 1990 883 890
13. H Goldblatt J Lynch RF Hanzal WW. Summerville Studies in experimental hypertension. 1. The production of persistent elevation of systolic blood pressure by means renal ischemia J Exp Med 59 1934 347 349
14. JD. Swales Renin-angiotensin system in hypertension Pharmacol Ther 7 1979 173 201
15. CI Johnson L Arnolda M. Hiwatari Angiotensin-converting enzyme inhibitors in the treatment of hypertension Drugs 27 1984 271 277
16. DE Longnecker ME Durieux KR Donovan ED Miller Jr MJ. Peach Saralasin dilates arterioles in SHR but not WKY rats Hypertension 6 1984 I106 I110
17. T Unger D Ganten RE Lang BA. Scholkens Persistent tissue converting enzyme inhibition following chronic treatment with Hoe498 and MD 421 in spontaneously hypertensive rats J Cardiovasc Pharmacol 7 1985 36 41
18. JP Rapp SM Wang H. Dene A genetic polymorphism in the renin gene of Dahl rat cosegregates with blood pressure Science 243 1989 542 544
19. JJ Mullins J Peters D. Ganten Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene Nature 344 1990 541 544
20. VJ. Dzau Vascular renin-angiotensin system and vascular protection J Cardiovasc Pharmacol 22 suppl 5 1993 S1 S9
21. JL Cook L Chen S Bhandaru GL Bakris RN. Re The use of antisense oligonucleotides to establish autocrine angiotensin growth effects in human neuroblastoma and mesangial cells Antisense Res Devel 2 1992 199 210
22. JA Oliver RR. Sciacca Local generation of angiotensin II as a mechanism of regulation of peripheral vascular tone in the rat J Clin Invest 74 1984 1247 1251
23. T Okamura M Miyazaki T Inagami N. Toda Vascular renin-angiotensin system in two-kidney, one clip hypertensive rats Hypertension 8 1986 560 565
24. H Schunkert VJ Dzau SS Tang AT Hirsch CS Apstein BH. Lorell Increased rat cardiac angiotensin-converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation J Clin Invest 86 1990 1913 1920
25. JL Cook S Bhandaru JF Giardina WC Claycomb RN. Re Identification and antisense inhibition of a renin-angiotensin system in transgenic cardiomyocytes Am J Physiol 268 1995 H1471 H1482
26. AA Geisterfer MJ Peach GK. Owens Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells Circ Res 62 1988 749 756
27. M Campbell-Boswell AL Robertson Jr. Effects of angiotensin II and vasopressin on human smooth muscle cells in vitro Exp Mol Pathol 35 1981 265 276
28. GK. Owens Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats Hypertension 9 1987 178 187
29. AJ Naftilan RE Pratt VJ. Dzau Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells J Clin Invest 83 1989 1419 1424
30. H Itoh M Mukoyama RE Pratt GH Gibbons VJ. Dzau Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II J Clin Invest 91 1993 2268 2274
31. GH Gibbons RE Pratt VJ. Dzau Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II J Clin Invest 90 1992 456 461
32. JW. McCubbin Peripheral effects of angiotensin on the autonomic nervous system FM Bumpus Angiotensin, pg IH. 1974 Verlag New York 417 422
33. PA. Khairallah Action of angiotensin on adrenergic nerve endings: inhibition of norepinephrine uptake Fed Proc 31 1972 1351 1357
34. SE Barrow CT Dollery DJ Heavey NE Hickling JM Ritter J. Mial Effect of vasoactive peptides on prostacyclin synthesis in man BR J Pharmacol 87 1986 243 247
35. G -mono-methyl-arginine attenuates the vasodilator action of bradykinin in the human forearm Br J Clin Pharmacol 38 1994 311 315
36. JV Mombouli S Illiano T Nagao T Scott-Burden PM. Vanhoutte Potentiation of endothelium-dependent relaxations to bradykinin by angiotensin-1 converting enzyme inhibitors in canie coronary arteries involves both endothelium derived relaxing and hyperpolarizing factors Circ Res 71 1992 137 144
37. B Hornig C Kohler H. Drexler Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans Circulation 95 1997 1115 1118
38. O Costerousse J Allegrini M Lopez F. Alhene-Gelas Angiotensin I-converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes Biochem J 290 1993 33 40
39. E Erdos RA. Skidgel The angiotensin I-converting enzyme Lab Invest 56 1987 345 348
40. F Alhene-Gelas J Richard D Courbon JM Warnet P. Corvol Distribution of plasma angiotensin I-converting enzyme levels in healthy men: relationship to environmental and hormonal parameters J Lab Clin Med 117 1991 33 39
41. F Soubrier X Jeunemaitre B Rigat AM Houot F Cambien P. Corvol Similar frequencies of renin gene restriction fragment length polymorphisms in hypertensive and normotensive subjects Hypertension 16 1990 712 717
42. AJ Naftilan R Williams D Burt M Paul RE Pratt P Hobart A lack of genetic linkage of renin gene restriction fragment length polymorphisms with human hypertension Hypertension 14 6 1989 614 618
43. WG Walker PK Whelton H Saito RP Russell J. Hermann Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ambulatory subjects Hypertension 1 1979 287 291
44. X Jeunemaitre F Soubrier YV Kotelevtsev RP Lifton CS Williams A Charru Molecular basis of human hypertension: role of angiotensinogen Cell 71 1992 169 180
45. X Jeunemaitre A Charru G Chatellier C Dumont P Sassaro F Soubrier M235T variant of the human angiotensinogen gene in unselected hypertensive patients J Hypertens 11 1993 S80 S81
46. M Caulfield P Lavender M Farrall P Monroe M Lawson P Turner AJL. Clark Linkage of the angiotensinogen gene to essential hypertension N Engl J Med 330 1994 1629 1633
47. RYL Zee YK Lou R Lyn BJ. Morris Association of a polymorphism of the angiotensin I-converting enzyme gene with essential hypertension Biochem Biophys Res Comm 184 1992 9 15
48. S Schmidt IM van Hooft DE Grobbee E. Ritz Polymorphism of the angiotensin I converting enzyme gene is apparently not related to high blood pressure: Dutch Hypertension and Offspring Study J Hypertens 11 1993 345 348
49. X Jeunemaitre RP Lifton SC Hunt Absence of linkage between the angiotensin-converting enzyme locus and human essential hypertension Nat Genet 1 1992 72 75
50. F Cambien O Poirier L Lecerf A Evans JP Cambou D Arveiler Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction Nature 359 1992 641 644
51. H Schunkert HW Hense SR Holmer M Stender S Perz U Keil Association between a deletion polymorphism of the angiotensin-converting enzyme gene and left ventricular hypertrophy N Engl J Med 330 1994 1634 1638
52. N Iwai N Ohmichi Y Nakamura M. Kinoshita DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy Circulation 90 1994 2622 2628
53. KE Berge K. Berg No effect of insertion/deletion polymorphism at the ACE locus on normal blood pressure level or variability Clin Genet 45 1994 169 174
54. CJ Lavie HO Ventura FH. Masserli Left ventricular hypertrophy and its relationship to obesity and hypertension Postgrad Med 91 1992 131 143
55. CJ Lavie HO Ventura FH. Masserli Regression of increased left ventricular mass by antihypertensives Drugs 42 1991 945 961
56. AJ Marian QT Yu R Workman G Greve R. Roberts Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death Lancet 342 1993 1085 1086
57. H Schunkert B Jackson SS Tang FJ Schoen JFM Smits CS Apstein Distribution and functional significance of cardiac angiotensin-converting enzyme in hypertrophied rat hearts Circulation 87 1993 1328 1339
58. KM Baker MI Chernin SK Wixson JF. Aceto Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats Am J Physiol 259 1990 H324 H332
59. HW Farber DM Center S Rounds SM. Danilov Components of the angiotensin system cause release of a neutrophil chemoattractant from cultured bovine and human endothelial cells Eur Heart J 11 suppl B 1990 100 107
60. S Keidar JG Brook M. Aviram Angiotensin II enhanced lipid peroxidation of low-density lipoprotein J Am Physiol Soc 8 1993 245 248
61. KM Finta MJ Fischer L Lee D Gordon B Pitt RC. Webb Ramipril prevents impaired endothelium-dependent relaxation in arteries from rabbits fed an atherogenic diet Atherosclerosis 100 1993 149 156
62. L Lind H Lithell L Wide S. Ljunghall Metabolic cardiovascular risk factors and the renin-aldosterone system in essential hypertension J Hum Hypertens 6 1992 27 29
63. AV Chobanian CC Haudenschild C Nickerson R. Drago Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit Hypertension 15 1990 327 331
64. J Ruiz H Blanche N Cohen G Velho F Cambien D Cohen Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus Proc Natl Acad Sci USA 91 1994 3662 3665
65. PM Ridker CL Gaboury PR Conlin EW Seely GH Williams DE. Vaughan Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function Circulation 87 1993 1969 1973
66. F Cambien O Costerousse L Tiret O Poirier L Lecerf MF Gonzales Plasma level and gene polymorphism of angiotensin-converting enzyme in relation to myocardial infarction Circulation 90 1994 669 676
67. M Bohn KE Berge A Bakken J Erikssen K. Berg Insertion/deletion (I/D) polymorphism at the locus for angiotensin I-converting enzyme and myocardial infarction Clin Genet 44 1993 292 297
68. K Lindpaintner MA Pfeffer R Kreutz MJ Stampfer F Grodstein F Lamotte A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease N Engl J Med 332 1995 706 711
69. L Tiret F Kee O Poirier V Nicaud L Lecerf A Evans Deletion polymorphism in angiotensin-converting enzyme gene associated with parental history of myocardial infarction Lancet 341 1993 991 992
70. RF Badenhop XL Wang DE. Wilcken Angiotensin-converting enzyme genotype in children and coronary events in their grandparents Circulation 91 1995 1655 1658
71. AE Evans O Poirier F Kee L Lecerf E McCrum T Falconer Polymorphisms of the angiotensin-converting-enzyme gene in subjects who die from coronary heart disease Q J Med 87 1994 211 214
72. MH Alderman S Madhavan WL Ooi H Cohen JE Sealey JA. Laragh Association of renin-sodium profile with the risk of myocardial infarction in patients with hypertension N Engl J Med 324 1991 1098 1104
73. AT Hirsch CE Talsness H Schunkert M Paul VJ. Dzau Tissue-specific activation of cardiac angiotensin-converting enzyme in experimental heart failure Circ Res 69 1991 475 482
74. MV Raynolds MR Bristow EV Bush WT Abraham BD Lowes LS Zisman Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy Lancet 342 1993 1073 1075
75. H Rakugi DK Kim JE Krieger DS Wang VJ Dzan RE. Pratt Induction of angiotensin-converting enzyme in the neointima after vascular injury. Possible role in restenosis J Clin Invest 93 1994 339 346
76. JS Powell JP Clozel RK Mullet H Kuhn F Hefti M Hosang Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury Science 245 1989 186 188
77. CH Kenneth SS Robert DE William AR Camrud KR Bailey MA Jorgenson Effect of angiotensin-converting enzyme inhibition on neointimal proliferation in a porcine coronary injury model Am Heart J 125 1993 695 701
78. RF Kaufmann JS Bean KM Zimmerman RF Brown MI. Steinberg Inhibition by DuP 753, a non-peptide angiotensin II antagonist, of neointima formation following balloon injury of rat carotid arteries [abstract] Circulation 84 1991 II-141
79. The Multicenter European Research Trial With Cilazapril After Angioplasty to Prevent Transluminal Coronary Obstruction and Restenosis MERCATOR study group Does the new angiotensin-converting enzyme inhibitor cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Results of the MERCATOR study: a multicenter, randomized, double-blind placebo-controlled trial Circulation 86 1992 100 110
80. M Ohishi K Fujii T Minamino A potent genetic risk factor for restenosis [letter] Nat Genet 5 1993 324 325
81. B Pitt R Segal FA Martinez G Meurers AJ Cowley I Thomas on behalf of ELITE Study Investigators Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study. ELITE) Lancet 349 1997 747 752