메뉴 건너뛰기




Volumn 62, Issue 2, 2004, Pages 299-308

Genetically modified mice: Tools to decode the functions of connexins in the heart - New models for cardiovascular research

Author keywords

Arrhythmia (mechanisms); Conduction (block); Connexins; Developmental biology; Sudden death

Indexed keywords

CONNEXIN 32; CONNEXIN 40; CONNEXIN 43; CONNEXIN 45; GAP JUNCTION PROTEIN; MYOSIN; RETINOIC ACID RECEPTOR ALPHA; STRESS ACTIVATED PROTEIN KINASE;

EID: 1942502918     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2004.02.010     Document Type: Review
Times cited : (55)

References (65)
  • 1
    • 1942438964 scopus 로고    scopus 로고
    • Gap junctions and the connexin protein family
    • [this issue]
    • Söhl G., Willecke K. Gap junctions and the connexin protein family. Cardiovasc. Res. 62:2004;228-232. [this issue].
    • (2004) Cardiovasc. Res. , vol.62 , pp. 228-232
    • Söhl, G.1    Willecke, K.2
  • 3
    • 0035704411 scopus 로고    scopus 로고
    • Emerging issues of connexin channels: Biophysics fills the gap
    • Harris A.L. Emerging issues of connexin channels: biophysics fills the gap. Q. Rev. Biophys. 34:2001;325-472.
    • (2001) Q. Rev. Biophys. , vol.34 , pp. 325-472
    • Harris, A.L.1
  • 4
    • 1942494492 scopus 로고    scopus 로고
    • Biophysical properties of channels and hemichannels formed by cardiac connexins. An approach to heteromericity
    • [this issue]
    • Moreno A. Biophysical properties of channels and hemichannels formed by cardiac connexins. An approach to heteromericity. Cardiovasc. Res. 2004;. [this issue].
    • (2004) Cardiovasc. Res.
    • Moreno, A.1
  • 5
    • 0028907907 scopus 로고
    • Cardiac malformation in neonatal mice lacking connexin43
    • Réaume A.G., de Sousa P.A., Kulkarni S.et al. Cardiac malformation in neonatal mice lacking connexin43. Science. 267:1995;1831-1834.
    • (1995) Science , vol.267 , pp. 1831-1834
    • Réaume, A.G.1    De Sousa, P.A.2    Kulkarni, S.3
  • 6
    • 0034283421 scopus 로고    scopus 로고
    • Abnormal cardiac conduction and morphogenesis in connexin40 and connexin43 double-deficient mice
    • Kirchhoff S., Kim J.-S., Hagendorff A.et al. Abnormal cardiac conduction and morphogenesis in connexin40 and connexin43 double-deficient mice. Circ. Res. 87:2000;399-405.
    • (2000) Circ. Res. , vol.87 , pp. 399-405
    • Kirchhoff, S.1    Kim, J.-S.2    Hagendorff, A.3
  • 7
    • 0032559623 scopus 로고    scopus 로고
    • Heart defects in connexin43-deficient mice
    • Ya J., Erdtsieck-Ernste E.B., de Boer P.A.et al. Heart defects in connexin43-deficient mice. Circ. Res. 82:1998;360-366.
    • (1998) Circ. Res. , vol.82 , pp. 360-366
    • Ya, J.1    Erdtsieck-Ernste, E.B.2    De Boer, P.A.3
  • 8
    • 0032100436 scopus 로고    scopus 로고
    • Alteration in connexin43 gap junction gene dosage impairs conotruncal heart development
    • Huang G.Y., Wessels A., Smith B.R., Linask K.K., Ewart J.L., Lo C.W. Alteration in connexin43 gap junction gene dosage impairs conotruncal heart development. Dev. Biol. 198:1998;32-44.
    • (1998) Dev. Biol. , vol.198 , pp. 32-44
    • Huang, G.Y.1    Wessels, A.2    Smith, B.R.3    Linask, K.K.4    Ewart, J.L.5    Lo, C.W.6
  • 9
    • 0036333778 scopus 로고    scopus 로고
    • An essential role for connexin43 gap junctions in mouse coronary artery development
    • Li W.E., Waldo K., Linask K.L.et al. An essential role for connexin43 gap junctions in mouse coronary artery development. Development. 129:2002;2031-2042.
    • (2002) Development , vol.129 , pp. 2031-2042
    • Li, W.E.1    Waldo, K.2    Linask, K.L.3
  • 10
    • 0030960952 scopus 로고    scopus 로고
    • Cx43 gap junction gene expression and gap junctional communication in mouse neural crest cells
    • Lo C.W., Cohen M.F., Huang G.Y.et al. Cx43 gap junction gene expression and gap junctional communication in mouse neural crest cells. Dev. Genet. 20:1997;119-132.
    • (1997) Dev. Genet. , vol.20 , pp. 119-132
    • Lo, C.W.1    Cohen, M.F.2    Huang, G.Y.3
  • 11
    • 0033560865 scopus 로고    scopus 로고
    • Connexin43 expression reflects neural crest patterns during cardiovascular development
    • Waldo K.L., Lo C.W., Kirby M.L. Connexin43 expression reflects neural crest patterns during cardiovascular development. Dev. Biol. 208:1999;307-323.
    • (1999) Dev. Biol. , vol.208 , pp. 307-323
    • Waldo, K.L.1    Lo, C.W.2    Kirby, M.L.3
  • 12
    • 0030972376 scopus 로고    scopus 로고
    • Heart and neural tube defects in transgenic mice overexpressing the Cx43 gap junction gene
    • Ewart J.L., Cohen M.F., Meyer R.A.et al. Heart and neural tube defects in transgenic mice overexpressing the Cx43 gap junction gene. Development. 124:1997;1281-1292.
    • (1997) Development , vol.124 , pp. 1281-1292
    • Ewart, J.L.1    Cohen, M.F.2    Meyer, R.A.3
  • 13
    • 0032517847 scopus 로고    scopus 로고
    • Gap junction-mediated cell-cell communication modulates mouse neural crest migration
    • Huang G.Y., Cooper E.S., Waldo K., Kirby M.L., Gilula N.B., Lo C.W. Gap junction-mediated cell-cell communication modulates mouse neural crest migration. J. Cell Biol. 143:1998;1725-1734.
    • (1998) J. Cell Biol. , vol.143 , pp. 1725-1734
    • Huang, G.Y.1    Cooper, E.S.2    Waldo, K.3    Kirby, M.L.4    Gilula, N.B.5    Lo, C.W.6
  • 14
    • 0032373862 scopus 로고    scopus 로고
    • Heart malformations in transgenic mice exhibiting dominant negative inhibition of gap junctional communication in neural crest cells
    • Sullivan R., Huang G.Y., Meyer R.A., Wessels A., Linask K.K., Lo C.W. Heart malformations in transgenic mice exhibiting dominant negative inhibition of gap junctional communication in neural crest cells. Dev. Biol. 204:1998;224-234.
    • (1998) Dev. Biol. , vol.204 , pp. 224-234
    • Sullivan, R.1    Huang, G.Y.2    Meyer, R.A.3    Wessels, A.4    Linask, K.K.5    Lo, C.W.6
  • 15
    • 0035833252 scopus 로고    scopus 로고
    • Modulation of mouse neural crest cell mobility by N-cadherin and connexin43 gap junctions
    • Xu X., Li W.E., Huang G.Y.et al. Modulation of mouse neural crest cell mobility by N-cadherin and connexin43 gap junctions. J. Cell Biol. 154:2002;217-229.
    • (2002) J. Cell Biol. , vol.154 , pp. 217-229
    • Xu, X.1    Li, W.E.2    Huang, G.Y.3
  • 16
    • 0033117085 scopus 로고    scopus 로고
    • Gap junction communication and the modulation of cardiac neural crest cells
    • Lo C.W., Waldo K.L., Kirby M.L. Gap junction communication and the modulation of cardiac neural crest cells. Trends Cardiovasc. Med. 9:1999;63-69.
    • (1999) Trends Cardiovasc. Med. , vol.9 , pp. 63-69
    • Lo, C.W.1    Waldo, K.L.2    Kirby, M.L.3
  • 17
    • 0028237124 scopus 로고
    • Association of the cardiac neural crest with development of the coronary arteries in the chick embryo
    • Waldo K.L., Kuminski D.H., Kirby M.L. Association of the cardiac neural crest with development of the coronary arteries in the chick embryo. Anat. Rec. 239:1994;315-331.
    • (1994) Anat. Rec. , vol.239 , pp. 315-331
    • Waldo, K.L.1    Kuminski, D.H.2    Kirby, M.L.3
  • 18
    • 0035827720 scopus 로고    scopus 로고
    • Null mutation of connexin43 causes slow propagation of ventricular activation in the late stages of mouse embryonic development
    • Vaidya D., Tamaddon H.S., Lo C.W.et al. Null mutation of connexin43 causes slow propagation of ventricular activation in the late stages of mouse embryonic development. Circ. Res. 88:2001;1196-11202.
    • (2001) Circ. Res. , vol.88 , pp. 1196-11202
    • Vaidya, D.1    Tamaddon, H.S.2    Lo, C.W.3
  • 19
    • 0034620495 scopus 로고    scopus 로고
    • Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice
    • Lerner D.L., Yamada K.A., Schluessler R.B., Saffitz J.E. Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice. Circulation. 101:2000;547-552.
    • (2000) Circulation , vol.101 , pp. 547-552
    • Lerner, D.L.1    Yamada, K.A.2    Schluessler, R.B.3    Saffitz, J.E.4
  • 20
    • 0035895649 scopus 로고    scopus 로고
    • Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43
    • Gutstein D.E., Morley G.E., Tamaddon H.et al. Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43. Circ. Res. 88:2001;333-339.
    • (2001) Circ. Res. , vol.88 , pp. 333-339
    • Gutstein, D.E.1    Morley, G.E.2    Tamaddon, H.3
  • 21
    • 0142088520 scopus 로고    scopus 로고
    • Cell coupling between ventricular myocyte pairs from connexin43-deficient murine hearts
    • Yao J.A., Guststein D.E., Liu F., Fishman G.I., Wit A.L. Cell coupling between ventricular myocyte pairs from connexin43-deficient murine hearts. Circ. Res. 93:2003;736-743.
    • (2003) Circ. Res. , vol.93 , pp. 736-743
    • Yao, J.A.1    Guststein, D.E.2    Liu, F.3    Fishman, G.I.4    Wit, A.L.5
  • 22
    • 0037348756 scopus 로고    scopus 로고
    • The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions
    • Gutstein D.E., Liu F.Y., Meyers M.B., Choo A., Fishman G.I. The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions. J. Cell Sci. 116:2003;875-885.
    • (2003) J. Cell Sci. , vol.116 , pp. 875-885
    • Gutstein, D.E.1    Liu, F.Y.2    Meyers, M.B.3    Choo, A.4    Fishman, G.I.5
  • 24
    • 1442359119 scopus 로고    scopus 로고
    • Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43
    • Van Rijen H.M.V., Eckardt D., Degen J.et al. Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43. Circ. Res. 109:2004;1048-1054.
    • (2004) Circ. Res. , vol.109 , pp. 1048-1054
    • Van Rijen, H.M.V.1    Eckardt, D.2    Degen, J.3
  • 25
    • 0037019966 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes
    • Petrich B.G., Gong X., Lerner D.L.et al. c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes. Circ. Res. 91:2002;640-647.
    • (2002) Circ. Res. , vol.91 , pp. 640-647
    • Petrich, B.G.1    Gong, X.2    Lerner, D.L.3
  • 26
    • 0035806899 scopus 로고    scopus 로고
    • Heterogeneous expression of gap junction channels in the heart leads to conduction defects and ventricular dysfunction
    • Gutstein D.E., Morley G.E., Vaidya D.et al. Heterogeneous expression of gap junction channels in the heart leads to conduction defects and ventricular dysfunction. Circulation. 104:2001;1194-1199.
    • (2001) Circulation , vol.104 , pp. 1194-1199
    • Gutstein, D.E.1    Morley, G.E.2    Vaidya, D.3
  • 27
    • 0036772413 scopus 로고    scopus 로고
    • Remodeling of gap junctions in mouse hearts hypertrophied by forced retinoic acid signaling
    • Van Veen T.A., van Rijen H.M.V., Wiegerinck R.F.et al. Remodeling of gap junctions in mouse hearts hypertrophied by forced retinoic acid signaling. J. Mol. Cell. Cardiol. 34:2002;1411-1423.
    • (2002) J. Mol. Cell. Cardiol. , vol.34 , pp. 1411-1423
    • Van Veen, T.A.1    Van Rijen, H.M.V.2    Wiegerinck, R.F.3
  • 28
    • 0037454041 scopus 로고    scopus 로고
    • Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice
    • Kanno S., Kovacs A., Yamada K.A., Saffitz J.E. Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice. J. Am. Coll. Cardiol. 41:2003;681-686.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 681-686
    • Kanno, S.1    Kovacs, A.2    Yamada, K.A.3    Saffitz, J.E.4
  • 29
    • 18244411722 scopus 로고    scopus 로고
    • Downregulation of connexin45 gene products during mouse heart development
    • Alcoléa S., Théveniau-Ruissy M., Jarry-Guichard T.et al. Downregulation of connexin45 gene products during mouse heart development. Circ. Res. 84:1999;1365-1379.
    • (1999) Circ. Res. , vol.84 , pp. 1365-1379
    • Alcoléa, S.1    Théveniau-Ruissy, M.2    Jarry-Guichard, T.3
  • 30
    • 0030792079 scopus 로고    scopus 로고
    • Expression pattern of connexin genes products at the early developmental stages of the mouse cardiovascular system
    • Delorme B., Dahl E., Jarry-Guichard T.et al. Expression pattern of connexin genes products at the early developmental stages of the mouse cardiovascular system. Circ. Res. 81:1997;423-437.
    • (1997) Circ. Res. , vol.81 , pp. 423-437
    • Delorme, B.1    Dahl, E.2    Jarry-Guichard, T.3
  • 31
    • 0030983063 scopus 로고    scopus 로고
    • Slow ventricular conduction in mice heterozygous for a connexin43 null mutation
    • Guerrero P.A., Schuessler R.B., Davis L.M.et al. Slow ventricular conduction in mice heterozygous for a connexin43 null mutation. J. Clin. Invest. 99:1997;1991-1998.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1991-1998
    • Guerrero, P.A.1    Schuessler, R.B.2    Davis, L.M.3
  • 32
    • 0032562189 scopus 로고    scopus 로고
    • Disparate effects of deficient expression of connexin43 on atrial and ventricular conduction: Evidence for chamber-specific molecular determinants of conduction
    • Thomas S.A., Schuessler R.B., Berul C.I.et al. Disparate effects of deficient expression of connexin43 on atrial and ventricular conduction: evidence for chamber-specific molecular determinants of conduction. Circulation. 97:1998;686-691.
    • (1998) Circulation , vol.97 , pp. 686-691
    • Thomas, S.A.1    Schuessler, R.B.2    Berul, C.I.3
  • 34
    • 0036193885 scopus 로고    scopus 로고
    • Redistribution of connexin45 in gap junctions of connexin43-deficient hearts
    • Johnson C.M., Kanter E.M., Green K.G.et al. Redistribution of connexin45 in gap junctions of connexin43-deficient hearts. Cardiovasc. Res. 53:2002;921-935.
    • (2002) Cardiovasc. Res. , vol.53 , pp. 921-935
    • Johnson, C.M.1    Kanter, E.M.2    Green, K.G.3
  • 35
    • 0034083070 scopus 로고    scopus 로고
    • Effects of diminished expression of connexin43 on gap junction number and size in ventricular myocradium
    • Saffitz J.E., Green K.G., Kraft W.J., Schechtman K.B., Yamada K.A. Effects of diminished expression of connexin43 on gap junction number and size in ventricular myocradium. Am. J. Physiol. 278:2000;H1662-H1670.
    • (2000) Am. J. Physiol. , vol.278 , pp. 1662-H1670
    • Saffitz, J.E.1    Green, K.G.2    Kraft, W.J.3    Schechtman, K.B.4    Yamada, K.A.5
  • 37
    • 0036487237 scopus 로고    scopus 로고
    • Cardiac structure and function in young and senescent mice heterozygous for a connexin43 mutation
    • Betsuyaku T., Kovacs A., Saffitz J.E., Yamada K.A. Cardiac structure and function in young and senescent mice heterozygous for a connexin43 mutation. J. Mol. Cell. Cardiol. 34:2002;175-184.
    • (2002) J. Mol. Cell. Cardiol. , vol.34 , pp. 175-184
    • Betsuyaku, T.1    Kovacs, A.2    Saffitz, J.E.3    Yamada, K.A.4
  • 38
    • 0032851539 scopus 로고    scopus 로고
    • Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping
    • Morley G.E., Vaidya D., Samie F.H., Lo C., Delmar M., Jalife J. Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping. J. Cardiovasc. Electrophysiol. 10:1999;1361-1375.
    • (1999) J. Cardiovasc. Electrophysiol. , vol.10 , pp. 1361-1375
    • Morley, G.E.1    Vaidya, D.2    Samie, F.H.3    Lo, C.4    Delmar, M.5    Jalife, J.6
  • 39
    • 0037704231 scopus 로고    scopus 로고
    • Impulse propagation in synthetic strands of neonatal cardiac myocytes with genetically reduced levels of connexin43
    • Thomas S.P., Kucera J.P., Bircher-Lehman L., Rudy Y., Saffitz J.E., Kléber A. Impulse propagation in synthetic strands of neonatal cardiac myocytes with genetically reduced levels of connexin43. Circ. Res. 92:2003;1209-1216.
    • (2003) Circ. Res. , vol.92 , pp. 1209-1216
    • Thomas, S.P.1    Kucera, J.P.2    Bircher-Lehman, L.3    Rudy, Y.4    Saffitz, J.E.5    Kléber, A.6
  • 40
    • 0034705469 scopus 로고    scopus 로고
    • Gap junctions in cardiovascular disease
    • Jongsma H.J., Wilders R. Gap junctions in cardiovascular disease. Circ. Res. 86:2000;1193-1197.
    • (2000) Circ. Res. , vol.86 , pp. 1193-1197
    • Jongsma, H.J.1    Wilders, R.2
  • 41
    • 0034699350 scopus 로고    scopus 로고
    • Unique and shared functions of different connexins in mice
    • Plum A., Hallas G., Magin T.et al. Unique and shared functions of different connexins in mice. Curr. Biol. 10:2000;1083-1091.
    • (2000) Curr. Biol. , vol.10 , pp. 1083-1091
    • Plum, A.1    Hallas, G.2    Magin, T.3
  • 42
    • 0032567887 scopus 로고    scopus 로고
    • Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
    • Simon A.M., Goodenough D.A., Paul D.L. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr. Biol. 8:1998;295-298.
    • (1998) Curr. Biol. , vol.8 , pp. 295-298
    • Simon, A.M.1    Goodenough, D.A.2    Paul, D.L.3
  • 43
    • 0032567957 scopus 로고    scopus 로고
    • Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice
    • Kirchhoff S., Nelles E., Hagendorff A., Krüger O., Traub O., Willecke K. Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr. Biol. 8:1998;299-302.
    • (1998) Curr. Biol. , vol.8 , pp. 299-302
    • Kirchhoff, S.1    Nelles, E.2    Hagendorff, A.3    Krüger, O.4    Traub, O.5    Willecke, K.6
  • 44
    • 0043026950 scopus 로고    scopus 로고
    • High incidence of cardiac malformations in connexin40-deficient mice
    • Gu H., Smith F.C., Taffet S.M., Delmar M. High incidence of cardiac malformations in connexin40-deficient mice. Circ. Res. 93:2003;201-206.
    • (2003) Circ. Res. , vol.93 , pp. 201-206
    • Gu, H.1    Smith, F.C.2    Taffet, S.M.3    Delmar, M.4
  • 45
    • 0033596919 scopus 로고    scopus 로고
    • Conduction disturbances and increased atrial vulnerability in connexin40-deficient mice analyzed by transesophageal stimulation
    • Hagendorff A., Schumacher B., Kirchhoff S., Luderitz B., Willecke K. Conduction disturbances and increased atrial vulnerability in connexin40-deficient mice analyzed by transesophageal stimulation. Circulation. 99:1999;1508-1515.
    • (1999) Circulation , vol.99 , pp. 1508-1515
    • Hagendorff, A.1    Schumacher, B.2    Kirchhoff, S.3    Luderitz, B.4    Willecke, K.5
  • 47
    • 0034634288 scopus 로고    scopus 로고
    • High-resolution optical mapping of the right bundle branch in connexin40 knockout mice reveals slow conduction in the specialized conduction system
    • Tamaddon H.S., Vaidya D., Simon A.M., Paul D.L., Jalife J., Morley G.E. High-resolution optical mapping of the right bundle branch in connexin40 knockout mice reveals slow conduction in the specialized conduction system. Circ. Res. 87:2000;929-936.
    • (2000) Circ. Res. , vol.87 , pp. 929-936
    • Tamaddon, H.S.1    Vaidya, D.2    Simon, A.M.3    Paul, D.L.4    Jalife, J.5    Morley, G.E.6
  • 48
    • 0033756670 scopus 로고    scopus 로고
    • Connexin40-deficient mice exhibit atrio-ventricular nodal and infra-Hisian conduction abnormalities
    • Vanderbrink B.A., Sellitto C., Saba S.et al. Connexin40-deficient mice exhibit atrio-ventricular nodal and infra-Hisian conduction abnormalities. J. Cardiovasc. Electrophysiol. 11:2000;1270-1276.
    • (2000) J. Cardiovasc. Electrophysiol. , vol.11 , pp. 1270-1276
    • Vanderbrink, B.A.1    Sellitto, C.2    Saba, S.3
  • 49
    • 0033710745 scopus 로고    scopus 로고
    • A targeted disruption in connexin40 leads to distinct atrioventricular conduction defects
    • Bevilacqua L.M., Simon A.M., Maguire C.T.et al. A targeted disruption in connexin40 leads to distinct atrioventricular conduction defects. J. Interv. Card. Electrophysiol. 4:2000;459-467.
    • (2000) J. Interv. Card. Electrophysiol. , vol.4 , pp. 459-467
    • Bevilacqua, L.M.1    Simon, A.M.2    Maguire, C.T.3
  • 50
    • 0035916936 scopus 로고    scopus 로고
    • Impaired conduction in the bundle branches of mouse hearts lacking the gap junction protein connexin40
    • Van Rijen H.V.M., van Veen T.A., van Kempen M.J.et al. Impaired conduction in the bundle branches of mouse hearts lacking the gap junction protein connexin40. Circulation. 103:2001;1591-1598.
    • (2001) Circulation , vol.103 , pp. 1591-1598
    • Van Rijen, H.V.M.1    Van Veen, T.A.2    Van Kempen, M.J.3
  • 51
    • 0037286898 scopus 로고    scopus 로고
    • Comparison of connexin expression patterns in the developing mouse heart and human foetal heart
    • Coppen S.R., Kaba R.A., Halliday D.et al. Comparison of connexin expression patterns in the developing mouse heart and human foetal heart. Mol. Cell. Biochem. 242:2003;121-127.
    • (2003) Mol. Cell. Biochem. , vol.242 , pp. 121-127
    • Coppen, S.R.1    Kaba, R.A.2    Halliday, D.3
  • 52
    • 0037155776 scopus 로고    scopus 로고
    • Transcriptional regulation of vertebrate cardiac morphogenesis
    • Bruneau B. Transcriptional regulation of vertebrate cardiac morphogenesis. Circ. Res. 90:2002;509-519.
    • (2002) Circ. Res. , vol.90 , pp. 509-519
    • Bruneau, B.1
  • 53
    • 9144245551 scopus 로고    scopus 로고
    • Replacement of connexin40 by connexin45 in the mouse. Impact on cardiac electrical conduction system
    • Alcoléa S., Jarry-Guichard T., de Bakker J.M.T.et al. Replacement of connexin40 by connexin45 in the mouse. Impact on cardiac electrical conduction system. Circ. Res. 94:2004;100-109.
    • (2004) Circ. Res. , vol.94 , pp. 100-109
    • Alcoléa, S.1    Jarry-Guichard, T.2    De Bakker, J.M.T.3
  • 54
    • 0033041407 scopus 로고    scopus 로고
    • Connexin45 (α6) expression delineates an extended conduction system in the embryonic and mature rodent heart
    • Coppen S.R., Severs N.J., Gourdie R.G. Connexin45 (α6) expression delineates an extended conduction system in the embryonic and mature rodent heart. Dev. Genet. 24:1999;82-90.
    • (1999) Dev. Genet. , vol.24 , pp. 82-90
    • Coppen, S.R.1    Severs, N.J.2    Gourdie, R.G.3
  • 56
    • 0033756717 scopus 로고    scopus 로고
    • Defective vascular development in connexin45-deficient mice
    • Krüger O., Plum A., Kim J.-S.et al. Defective vascular development in connexin45-deficient mice. Development. 127:2000;4179-4193.
    • (2000) Development , vol.127 , pp. 4179-4193
    • Krüger, O.1    Plum, A.2    Kim, J.-S.3
  • 57
    • 0034780381 scopus 로고    scopus 로고
    • Regulation of the epithelial-mesenchymal transformation through gap junction channels in heart development
    • Nishii K., Kumai M., Shibata Y. Regulation of the epithelial-mesenchymal transformation through gap junction channels in heart development. Trends Cardiovasc. Med. 11:2001;213-218.
    • (2001) Trends Cardiovasc. Med. , vol.11 , pp. 213-218
    • Nishii, K.1    Kumai, M.2    Shibata, Y.3
  • 58
    • 0346496105 scopus 로고    scopus 로고
    • Mice lacking connexin45 conditionally in cardiac myocytes display embryonic lethality similar to that of germline knockout mice without endocardial cushion defect
    • Nishii K., Kumai M., Egashira K., Miwa T.et al. Mice lacking connexin45 conditionally in cardiac myocytes display embryonic lethality similar to that of germline knockout mice without endocardial cushion defect. Cell Commun. Adhesion. 10:2003;365-369.
    • (2003) Cell Commun. Adhesion , vol.10 , pp. 365-369
    • Nishii, K.1    Kumai, M.2    Egashira, K.3    Miwa, T.4
  • 59
    • 0346634892 scopus 로고    scopus 로고
    • Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis
    • Hove J.R., Köster R.W., Forouhar A.S., Acevedo-Bolton G., Fraser S.E., Gharib M. Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis. Nature. 421:2003;172-177.
    • (2003) Nature , vol.421 , pp. 172-177
    • Hove, J.R.1    Köster, R.W.2    Forouhar, A.S.3    Acevedo-Bolton, G.4    Fraser, S.E.5    Gharib, M.6
  • 60
    • 0345971292 scopus 로고    scopus 로고
    • Embryonic atrial function is essential for mouse embryogenesis, cardiac morphogenesis and angiogenesis
    • Huang C., Sheikh F., Hollander M.et al. Embryonic atrial function is essential for mouse embryogenesis, cardiac morphogenesis and angiogenesis. Development. 130:2003;6111-6119.
    • (2003) Development , vol.130 , pp. 6111-6119
    • Huang, C.1    Sheikh, F.2    Hollander, M.3
  • 62
    • 0035663441 scopus 로고    scopus 로고
    • Mutations in GJA1 (connexin43) are associated with on-syndromic autosomal recessive deafness
    • Liu X.Z., Xia X.J., Adams J.et al. Mutations in GJA1 (connexin43) are associated with on-syndromic autosomal recessive deafness. Hum. Mol. Genet. 10:2001;2945-2951.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2945-2951
    • Liu, X.Z.1    Xia, X.J.2    Adams, J.3
  • 63
    • 0037320927 scopus 로고    scopus 로고
    • Connexin43 (GJA1) mutations cause the pleiotropic phenotype of oculodentodigital dysplasia
    • Paznekas W.A., Boyadjiev S.A., Shapiro R.E.et al. Connexin43 (GJA1) mutations cause the pleiotropic phenotype of oculodentodigital dysplasia. Am. J. Hum. Genet. 72:2003;408-418.
    • (2003) Am. J. Hum. Genet. , vol.72 , pp. 408-418
    • Paznekas, W.A.1    Boyadjiev, S.A.2    Shapiro, R.E.3
  • 64
    • 0037428063 scopus 로고    scopus 로고
    • A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill
    • Groenewegen W.A., Firouzi M., Bezzina C.R.et al. A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill. Circ. Res. 92:2003;14-22.
    • (2003) Circ. Res. , vol.92 , pp. 14-22
    • Groenewegen, W.A.1    Firouzi, M.2    Bezzina, C.R.3
  • 65
    • 0030248881 scopus 로고    scopus 로고
    • Connexins in mammalian heart function
    • Gros D., Jongsma H.J. Connexins in mammalian heart function. BioEssays. 18:1996;719-730.
    • (1996) BioEssays , vol.18 , pp. 719-730
    • Gros, D.1    Jongsma, H.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.