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Volumn 278, Issue 6 47-6, 2000, Pages

Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype

Author keywords

Long Q T syndrome; Programmed stimulation; Q T interval; Transgenic mice; Ventricular arrhythmias

Indexed keywords

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DISEASE ASSOCIATION; ELECTROPHYSIOLOGY; HEART VENTRICLE TACHYCARDIA; HUMAN; LONG QT SYNDROME; MOUSE; PRIORITY JOURNAL; QT INTERVAL; TRANSGENIC MOUSE;

EID: 0033948513     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.278.6.h1891     Document Type: Article
Times cited : (53)

References (22)
  • 2
    • 0028264963 scopus 로고
    • Assembly of mammalian voltage-gated potassium channels: Evidence for an important role of the first transmembrane segment
    • Babila T, Moscucci A, Wang H, Weaver FE, and Koren G. Assembly of mammalian voltage-gated potassium channels: evidence for an important role of the first transmembrane segment. Neuron 12: 615-626, 1994.
    • (1994) Neuron , vol.12 , pp. 615-626
    • Babila, T.1    Moscucci, A.2    Wang, H.3    Weaver, F.E.4    Koren, G.5
  • 4
    • 0032494172 scopus 로고    scopus 로고
    • Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominantnegative Kv4 alpha subunit
    • Barry DM, Xu H, Schuessler RB, and Nerbonne JM. Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominantnegative Kv4 alpha subunit. Circ Res 83:560-567, 1998.
    • (1998) Circ Res , vol.83 , pp. 560-567
    • Barry, D.M.1    Xu, H.2    Schuessler, R.B.3    Nerbonne, J.M.4
  • 7
    • 0031467877 scopus 로고    scopus 로고
    • Electrophysiological mechanism of the characteristic electrocardiographic morphology of torsade de pointes tachyarrhythmias in the long-QT syndrome
    • El-Sherif M, Chinushi M, Caref EB, and Restivo M. Electrophysiological mechanism of the characteristic electrocardiographic morphology of torsade de pointes tachyarrhythmias in the long-QT syndrome. Circulation 96: 4392-4397, 1997.
    • (1997) Circulation , vol.96 , pp. 4392-4397
    • El-Sherif, M.1    Chinushi, M.2    Caref, E.B.3    Restivo, M.4
  • 9
    • 0033524661 scopus 로고    scopus 로고
    • Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system
    • Kupershmidt S, Yang T, Anderson ME, Wessels A, Niswender KD, Magnuson MA, and Roden DM. Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system. Circ Res 84: 146-152, 1999.
    • (1999) Circ Res , vol.84 , pp. 146-152
    • Kupershmidt, S.1    Yang, T.2    Anderson, M.E.3    Wessels, A.4    Niswender, K.D.5    Magnuson, M.A.6    Roden, D.M.7
  • 10
    • 0030614462 scopus 로고    scopus 로고
    • The human Δ1261 mutation of the HERG potassium channel results in a truncated protein that contains a subunit interaction domain and decreases the channel expression
    • Li X, Xu J, and Li M. The human Δ1261 mutation of the HERG potassium channel results in a truncated protein that contains a subunit interaction domain and decreases the channel expression. J Biol Chem 272: 705-708, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 705-708
    • Li, X.1    Xu, J.2    Li, M.3
  • 11
    • 0029160705 scopus 로고
    • Heart and lung disease in engineered mice
    • Lin MC, Rockman RA, and Chien KR. Heart and lung disease in engineered mice. Nat Med 1: 749-751, 1995.
    • (1995) Nat Med , vol.1 , pp. 749-751
    • Lin, M.C.1    Rockman, R.A.2    Chien, K.R.3
  • 12
    • 0032539808 scopus 로고    scopus 로고
    • Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel
    • London B, Jeron A, Zhou J, Buckett P, Han X, Mitchell GF, and Koren G. Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel. Proc Natl Acad Sci USA 95: 2626-2931, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2626-2931
    • London, B.1    Jeron, A.2    Zhou, J.3    Buckett, P.4    Han, X.5    Mitchell, G.F.6    Koren, G.7
  • 13
    • 0015091858 scopus 로고
    • Evaluation of sino-atrial node function in man by overdrive suppression
    • Mandel W, Hayakawa H, Danzig R, and Marcus HS. Evaluation of sino-atrial node function in man by overdrive suppression. Circulation 44: 59-66, 1971.
    • (1971) Circulation , vol.44 , pp. 59-66
    • Mandel, W.1    Hayakawa, H.2    Danzig, R.3    Marcus, H.S.4
  • 14
  • 15
    • 12944301900 scopus 로고    scopus 로고
    • Sudden death and the idiopathic long Q-T syndrome
    • Moss AJ and Schwartz PJ. Sudden death and the idiopathic long Q-T syndrome. Am J Med 66: 67, 1997.
    • (1997) Am J Med , vol.66 , pp. 67
    • Moss, A.J.1    Schwartz, P.J.2
  • 20
    • 0027971671 scopus 로고
    • Electrical turbulence in three-dimensional heart muscle
    • Winfree AT. Electrical turbulence in three-dimensional heart muscle. Science 266: 1003-1006, 1994.
    • (1994) Science , vol.266 , pp. 1003-1006
    • Winfree, A.T.1
  • 21
    • 0032547815 scopus 로고    scopus 로고
    • Characterization of a Kv1.5-encoded slowly inactivating outward current in adult mouse ventricular myocytes
    • Zhou J, Jeron A, London B, Han X, and Koren G. Characterization of a Kv1.5-encoded slowly inactivating outward current in adult mouse ventricular myocytes. Circ Res 83: 806-814, 1998.
    • (1998) Circ Res , vol.83 , pp. 806-814
    • Zhou, J.1    Jeron, A.2    London, B.3    Han, X.4    Koren, G.5
  • 22
    • 12944284030 scopus 로고    scopus 로고
    • Upregulation of a delayed rectifying outward current in LQT mouse ventricular myocytes
    • Zhou J, Murata M, Valverde P, and Koren G. Upregulation of a delayed rectifying outward current in LQT mouse ventricular myocytes (Abstract). Circulation 100: 1846, 1999.
    • (1999) Circulation , vol.100 , pp. 1846
    • Zhou, J.1    Murata, M.2    Valverde, P.3    Koren, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.