Inhibition of cardiac delayed rectifier K+ current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice

Circulation Research

Volumn 83, Issue 6, 1998, Pages 668-678

  Babij, Philip ^a   Askew, G Roger ^a   Nieuwenhuijsen, Bart ^a   Su, Chien Min ^a   Bridal, Terry R ^a   Jow, Brian ^a   Argentieri, Thomas M ^a   Kulik, John ^a   DeGennaro, Louis J ^a   Spinelli, Walter ^a   Colatsky, Thomas J ^a,b  

^a PFIZER INC   (United States)

^b WYETH AYERST RESEARCH   (United States)

Author keywords

Electrocardiography; HERG; Long QT syndrome; Mice, transgenic; Potassium channels

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; NISOLDIPINE; POTASSIUM ION;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; ELECTROCARDIOGRAPHY; FEMALE; GENE OVEREXPRESSION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CONDUCTION DISTURBANCE; HEART MUSCLE POTENTIAL; LONG QT SYNDROME; MALE; MOUSE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

EID: 0032556030     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.83.6.668     Document Type: Article

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