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Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 9, 2002, Pages 6210-6215

Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a

(12) Papadatos, G Alex a Wallerstein, Polly M R a Head, Catherine E G a Ratcliff, Rosemary a Brady, Peter A a Benndorf, Klaus c Saumarez, Richard C a,b Trezise, Ann E O d Huang, Christopher L H a Vandenberg, Jamie I a Colledge, William H a Grace, Andrew A a,b

a UNIVERSITY OF CAMBRIDGE (United Kingdom)

b UNIVERSITY OF CAMBRIDGE (United Kingdom)

c FRIEDRICH SCHILLER UNIVERSITY JENA (Germany)

d UNIVERSITY OF QUEENSLAND (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN SCN5A; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR BLOCK; ATRIOVENTRICULAR CONDUCTION; CHANNEL GATING; CONTROLLED STUDY; GENE DELETION; GENE DISRUPTION; GENE MUTATION; GENETIC ASSOCIATION; HEART DEPOLARIZATION; HEART MUSCLE EXCITABILITY; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; LETHALITY; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REENTRY ARRHYTHMIA; REFRACTORY PERIOD;

ANIMALS; CELL SURVIVAL; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; EXONS; HETEROZYGOTE; HOMOZYGOTE; MICE; MODELS, GENETIC; MUTATION; PATCH-CLAMP TECHNIQUES; PERFUSION; PHENOTYPE; SODIUM CHANNELS; TACHYCARDIA, VENTRICULAR;

ANIMALIA;

EID: 18344362987 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.082121299 Document Type: Article

Times cited : (332)

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