Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

EMBO Journal

Volumn 22, Issue 2, 2003, Pages 216-224

  Ludwig, Andreas ^a   Budde, Thomas ^b   Stieber, Juliane ^a   Moosmang, Sven ^a   Wahl, Christian ^c   Holthoff, Knut ^c   Langebartels, Anke ^d   Wotjak, Carsten ^d   Munsch, Thomas ^b   Zong, Xiangang ^c   Feil, Susanne ^a   Feil, Robert ^a   Lancel, Marike ^d   Chien, Kenneth R ^e   Konnerth, Arthur ^c   Pape, Hans Christian ^b   Biel, Martin ^c   Hofmann, Franz ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Epilepsy; HCN channel; Heart; Membrane potential; Pacemaker current

Indexed keywords

CATION CHANNEL; ION CHANNEL; PROTEIN; PROTEIN HCN2; UNCLASSIFIED DRUG;

ABSENCE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROCARDIOGRAM; ELECTROENCEPHALOGRAM; ELECTROPHYSIOLOGY; GENE DISRUPTION; GENE EXPRESSION; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART MUSCLE EXCITABILITY; HYPERPOLARIZATION; LOCOMOTION; MALE; MEMBRANE POTENTIAL; MEMBRANE STEADY POTENTIAL; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; NULL ALLELE; OSCILLATION; PACEMAKER; PRIORITY JOURNAL; SEIZURE; SINUS NODE; THALAMOCORTICAL TRACT;

ANIMALS; ARRHYTHMIA, SINUS; CEREBRAL CORTEX; ELECTROCARDIOGRAPHY; EPILEPSY, ABSENCE; GENE TARGETING; GENES, REPORTER; HEART RATE; ION CHANNELS; MALE; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOTOR ACTIVITY; MUSCLE PROTEINS; MYOCYTES, CARDIAC; NEURONS; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; RECOMBINATION, GENETIC; SINOATRIAL NODE; THALAMUS;

ANIMALIA;

EID: 0037439203     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg032     Document Type: Article

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