-
1
-
-
1242282390
-
Genes and genetics of murine lupus
-
ed. Lahita, R.G, Academic Press, San Diego
-
Kono, D.H., Baccala, R. & Theofilopoulos, A.N. Genes and genetics of murine lupus. in Systemic Lupus Erythematosus (ed. Lahita, R.G.) 225-263 (Academic Press, San Diego, 2004).
-
(2004)
Systemic Lupus Erythematosus
, pp. 225-263
-
-
Kono, D.H.1
Baccala, R.2
Theofilopoulos, A.N.3
-
2
-
-
20444485767
-
Cellular and genetic mechanisms of self tolerance and autoimmunity
-
Goodnow, C.C., Sprent, J., Fazekas de St Groth, B. & Vinuesa, C.G. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature 435, 590-597 (2005).
-
(2005)
Nature
, vol.435
, pp. 590-597
-
-
Goodnow, C.C.1
Sprent, J.2
Fazekas de St Groth, B.3
Vinuesa, C.G.4
-
3
-
-
33748051738
-
IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
-
Honda, K. & Taniguchi, T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat. Rev. Immunol. 6, 644-658 (2006).
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
4
-
-
18844457095
-
Mechanisms of type-I- and type-II-interferon-mediated signalling
-
Platanias, L.C. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5, 375-386 (2005).
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 375-386
-
-
Platanias, L.C.1
-
5
-
-
17644372733
-
IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
-
Liu, Y.J. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu. Rev. Immunol. 23, 275-306 (2005).
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 275-306
-
-
Liu, Y.J.1
-
6
-
-
17644402442
-
Type I interferons (/) in immunity and autoimmunity
-
Theofilopoulos, A.N., Baccala, R., Beutler, B. & Kono, D.H. Type I interferons (/) in immunity and autoimmunity. Annu. Rev. Immunol. 23, 307-335 (2005).
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 307-335
-
-
Theofilopoulos, A.N.1
Baccala, R.2
Beutler, B.3
Kono, D.H.4
-
7
-
-
33748447541
-
Type I interferon in systemic lupus erythematosus and other autoimmune diseases
-
Banchereau, J. & Pascual, V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25, 383-392 (2006).
-
(2006)
Immunity
, vol.25
, pp. 383-392
-
-
Banchereau, J.1
Pascual, V.2
-
8
-
-
33646477141
-
Lupus-like disease and high interferon levels corresponding to trisomy of the type I interferon cluster on chromosome 9p
-
Zhuang, H. et al. Lupus-like disease and high interferon levels corresponding to trisomy of the type I interferon cluster on chromosome 9p. Arthritis Rheum. 54, 1573-1579 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1573-1579
-
-
Zhuang, H.1
-
9
-
-
13844292408
-
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
-
Sigurdsson, S. et al. Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am. J. Hum. Genet. 76, 528-537 (2005).
-
(2005)
Am. J. Hum. Genet
, vol.76
, pp. 528-537
-
-
Sigurdsson, S.1
-
10
-
-
33646368404
-
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
-
Graham, R.R. et al. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat. Genet. 38, 550-555 (2006).
-
(2006)
Nat. Genet
, vol.38
, pp. 550-555
-
-
Graham, R.R.1
-
11
-
-
0037451124
-
Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice
-
Santiago-Raber, M.L. et al. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J. Exp. Med. 197, 777-788 (2003).
-
(2003)
J. Exp. Med
, vol.197
, pp. 777-788
-
-
Santiago-Raber, M.L.1
-
12
-
-
0037320208
-
Type I interferon controls the onset and severity of autoimmune manifestations in lpr mice
-
Braun, D., Geraldes, P., Demengeot, J. Type I interferon controls the onset and severity of autoimmune manifestations in lpr mice. J. Autoimmun. 20, 15-25 (2003).
-
(2003)
J. Autoimmun
, vol.20
, pp. 15-25
-
-
Braun, D.1
Geraldes, P.2
Demengeot, J.3
-
13
-
-
3242805826
-
Type I IFN protects against murine lupus
-
Hron, J.D. & Peng, S.L. Type I IFN protects against murine lupus. J. Immunol. 173, 2134-2142 (2004).
-
(2004)
J. Immunol
, vol.173
, pp. 2134-2142
-
-
Hron, J.D.1
Peng, S.L.2
-
14
-
-
33144466289
-
Interferon-β: A therapeutic for autoimmune lupus in MRL-Faslpr mice
-
Schwarting, A. et al. Interferon-β: a therapeutic for autoimmune lupus in MRL-Faslpr mice. J. Am. Soc. Nephrol. 16, 3264-3272 (2005).
-
(2005)
J. Am. Soc. Nephrol
, vol.16
, pp. 3264-3272
-
-
Schwarting, A.1
-
15
-
-
16244409253
-
Interferons as pathogenic effectors in autoimmunity
-
Baccala, R., Kono, D.H. & Theofilopoulos, A.N. Interferons as pathogenic effectors in autoimmunity. Immunol. Rev. 204, 9-26 (2005).
-
(2005)
Immunol. Rev
, vol.204
, pp. 9-26
-
-
Baccala, R.1
Kono, D.H.2
Theofilopoulos, A.N.3
-
16
-
-
22144457050
-
T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells
-
Zhu, J. et al. T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells. J. Clin. Invest. 115, 1869-1878 (2005).
-
(2005)
J. Clin. Invest
, vol.115
, pp. 1869-1878
-
-
Zhu, J.1
-
17
-
-
33644502594
-
Dendritic cell apoptosis in the maintenance of immune tolerance
-
Chen, M. et al. Dendritic cell apoptosis in the maintenance of immune tolerance. Science 311, 1160-1164 (2006).
-
(2006)
Science
, vol.311
, pp. 1160-1164
-
-
Chen, M.1
-
18
-
-
32044460431
-
Cutting edge: Enhancement of antibody responses through direct stimulation of B and T cells by type I IFN
-
Le Bon, A. et al. Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J. Immunol. 176, 2074-2078 (2006).
-
(2006)
J. Immunol
, vol.176
, pp. 2074-2078
-
-
Le Bon, A.1
-
19
-
-
0031962665
-
Impairment of T and B cell development by treatment with a type I interferon
-
Lin, Q., Dong, C. & Cooper, M.D. Impairment of T and B cell development by treatment with a type I interferon. J. Exp. Med. 187, 79-87 (1998).
-
(1998)
J. Exp. Med
, vol.187
, pp. 79-87
-
-
Lin, Q.1
Dong, C.2
Cooper, M.D.3
-
21
-
-
33646183566
-
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large
-
Beutler, B. et al. Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu. Rev. Immunol. 24, 353-389 (2006).
-
(2006)
Annu. Rev. Immunol
, vol.24
, pp. 353-389
-
-
Beutler, B.1
-
22
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki, A. & Medzhitov, R. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987-995 (2004).
-
(2004)
Nat. Immunol
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
23
-
-
33646899303
-
Sorting out Toll signals
-
Fitzgerald, K.A. & Chen, Z.J. Sorting out Toll signals. Cell 125, 834-836 (2006).
-
(2006)
Cell
, vol.125
, pp. 834-836
-
-
Fitzgerald, K.A.1
Chen, Z.J.2
-
24
-
-
20644450804
-
Negative regulation of toll-like receptor-mediated immune responses
-
Liew, F.Y., Xu, D., Brint, E.K. & O'Neill, L.A. Negative regulation of toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5, 446-458 (2005).
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
25
-
-
33748880024
-
DisSARMing Toll-like receptor signaling
-
O'Neill, L.A. DisSARMing Toll-like receptor signaling. Nat. Immunol. 7, 1023-1025 (2006).
-
(2006)
Nat. Immunol
, vol.7
, pp. 1023-1025
-
-
O'Neill, L.A.1
-
26
-
-
33744539798
-
Toll-like receptors and RNA helicases: Two parallel ways to trigger antiviral responses
-
Meylan, E. & Tschopp, J. Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol. Cell 22, 561-569 (2006).
-
(2006)
Mol. Cell
, vol.22
, pp. 561-569
-
-
Meylan, E.1
Tschopp, J.2
-
27
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato, H. et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105 (2006).
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
-
28
-
-
33750976374
-
5′-Triphosphate RNA is the ligand for RIG-I
-
Hornung, V. et al. 5′-Triphosphate RNA is the ligand for RIG-I. Science 314, 994-997 (2006).
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
-
29
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′ phosphates
-
Pichlmair, A. et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′ phosphates. Science 314, 997-1001 (2006).
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
-
30
-
-
33744791510
-
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
-
Gitlin, L. et al. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl. Acad. Sci. USA 103, 8459-8464 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8459-8464
-
-
Gitlin, L.1
-
31
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama, M. et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J. Immunol. 175, 2851-2858 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
-
32
-
-
26844503987
-
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I
-
Rothenfusser, S. et al. The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. J. Immunol. 175, 5260-5268 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 5260-5268
-
-
Rothenfusser, S.1
-
33
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson, D.B. & Medzhitov, R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24, 93-103 (2006).
-
(2006)
Immunity
, vol.24
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
34
-
-
33750369226
-
Toll-like receptors in systemic autoimmune disease
-
Marshak-Rothstein, A. Toll-like receptors in systemic autoimmune disease. Nat. Rev. Immunol. 6, 823-835 (2006).
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 823-835
-
-
Marshak-Rothstein, A.1
-
35
-
-
32444451688
-
The type I interferon system in systemic lupus erythematosus
-
Ronnblom, L., Eloranta, M.L. & Alm, G.V. The type I interferon system in systemic lupus erythematosus. Arthritis Rheum. 54, 408-420 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 408-420
-
-
Ronnblom, L.1
Eloranta, M.L.2
Alm, G.V.3
-
36
-
-
28544449709
-
Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
-
Vollmer, J. et al. Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. J. Exp. Med. 202, 1575-1585 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1575-1585
-
-
Vollmer, J.1
-
37
-
-
26844467349
-
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
-
Barrat, F.J. et al. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J. Exp. Med. 202, 1131-1139 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1131-1139
-
-
Barrat, F.J.1
-
38
-
-
33645741218
-
U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7
-
Savarese, E. et al. U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Blood 107, 3229-3234 (2006).
-
(2006)
Blood
, vol.107
, pp. 3229-3234
-
-
Savarese, E.1
-
39
-
-
28544440530
-
Autoantibodies make a U-turn: The toll hypothesis for auto-antibody specificity
-
Martin, D.A. & Elkon, K.B. Autoantibodies make a U-turn: the toll hypothesis for auto-antibody specificity. J. Exp. Med. 202, 1465-1469 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1465-1469
-
-
Martin, D.A.1
Elkon, K.B.2
-
40
-
-
33747815094
-
Endogenous TLR ligands and autoimmunity
-
Wagner, H. Endogenous TLR ligands and autoimmunity. Adv. Immunol. 91, 159-173 (2006).
-
(2006)
Adv. Immunol
, vol.91
, pp. 159-173
-
-
Wagner, H.1
-
41
-
-
3042548183
-
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
-
Boule, M.W. et al. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J. Exp. Med. 199, 1631-1640 (2004).
-
(2004)
J. Exp. Med
, vol.199
, pp. 1631-1640
-
-
Boule, M.W.1
-
42
-
-
85047693371
-
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9
-
Means, T.K. et al. Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. J. Clin. Invest. 115, 407-417 (2005).
-
(2005)
J. Clin. Invest
, vol.115
, pp. 407-417
-
-
Means, T.K.1
-
43
-
-
0020052580
-
Dna isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content
-
Sano, H.& Morimoto, C. Dna isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content. J. Immunol. 128, 1341-1345 (1982).
-
(1982)
J. Immunol
, vol.128
, pp. 1341-1345
-
-
Sano, H.1
Morimoto, C.2
-
44
-
-
29244471275
-
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA
-
Ishii, K.J. et al. A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat. Immunol. 7, 40-48 (2006).
-
(2006)
Nat. Immunol
, vol.7
, pp. 40-48
-
-
Ishii, K.J.1
-
45
-
-
33644889894
-
Intracellular mammalian DNA stimulates myeloid dendritic cells to produce type I interferons predominantly through a toll-like receptor 9-independent pathway
-
Martin, D.A. & Elkon, K.B. Intracellular mammalian DNA stimulates myeloid dendritic cells to produce type I interferons predominantly through a toll-like receptor 9-independent pathway. Arthritis Rheum. 54, 951-962 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 951-962
-
-
Martin, D.A.1
Elkon, K.B.2
-
46
-
-
14844351293
-
Nucleosome, the main autoantigen in systemic lupus erythematosus, induces direct dendritic cell activation via a MyD88-independent pathway: Consequences on inflammation
-
Decker, P., Singh-Jasuja, H., Haager, S., Kotter, I. & Rammensee, H.G. Nucleosome, the main autoantigen in systemic lupus erythematosus, induces direct dendritic cell activation via a MyD88-independent pathway: consequences on inflammation. J. Immunol. 174, 3326-3334 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 3326-3334
-
-
Decker, P.1
Singh-Jasuja, H.2
Haager, S.3
Kotter, I.4
Rammensee, H.G.5
-
47
-
-
33744804308
-
TLR9-independent activation of B lymphocytes by bacterial DNA
-
Cortez-Gonzalez, X. et al. TLR9-independent activation of B lymphocytes by bacterial DNA. DNA Cell Biol. 25, 253-261 (2006).
-
(2006)
DNA Cell Biol
, vol.25
, pp. 253-261
-
-
Cortez-Gonzalez, X.1
-
48
-
-
33646592188
-
The specific and essential role of MAVS in antiviral innate immune responses
-
Sun, Q. et al. The specific and essential role of MAVS in antiviral innate immune responses. Immunity 24, 633-642 (2006).
-
(2006)
Immunity
, vol.24
, pp. 633-642
-
-
Sun, Q.1
-
49
-
-
0034114882
-
Features of systemic lupus erythematosus in Dnase1-deficient mice
-
Napirei, M. et al. Features of systemic lupus erythematosus in Dnase1-deficient mice. Nat. Genet. 25, 177-181 (2000).
-
(2000)
Nat. Genet
, vol.25
, pp. 177-181
-
-
Napirei, M.1
-
50
-
-
6044262404
-
DNaseI in pathogenesis of systemic lupus erythematosus
-
Tsukumo, S. & Yasutomo, K. DNaseI in pathogenesis of systemic lupus erythematosus. Clin. Immunol. 113, 14-18 (2004).
-
(2004)
Clin. Immunol
, vol.113
, pp. 14-18
-
-
Tsukumo, S.1
Yasutomo, K.2
-
51
-
-
10444251052
-
Novel DNASE I mutations related to systemic lupus erythematosus
-
Bodano, A., Amarelo, J., Gonzalez, A., Gomez-Reino, J.J. & Conde, C. Novel DNASE I mutations related to systemic lupus erythematosus. Arthritis Rheum. 50, 4070-4071 (2004).
-
(2004)
Arthritis Rheum
, vol.50
, pp. 4070-4071
-
-
Bodano, A.1
Amarelo, J.2
Gonzalez, A.3
Gomez-Reino, J.J.4
Conde, C.5
-
52
-
-
12344290452
-
Lethal anemia caused by interferon- produced in mouse embryos carrying undigested DNA
-
Yoshida, H., Okabe, Y., Kawane, K., Fukuyama, H. & Nagata, S. Lethal anemia caused by interferon- produced in mouse embryos carrying undigested DNA. Nat. Immunol. 6, 49-56 (2005).
-
(2005)
Nat. Immunol
, vol.6
, pp. 49-56
-
-
Yoshida, H.1
Okabe, Y.2
Kawane, K.3
Fukuyama, H.4
Nagata, S.5
-
53
-
-
27944453599
-
Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
-
Okabe, Y., Kawane, K., Akira, S., Taniguchi, T. & Nagata, S. Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J. Exp. Med. 202, 1333-1339 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1333-1339
-
-
Okabe, Y.1
Kawane, K.2
Akira, S.3
Taniguchi, T.4
Nagata, S.5
-
54
-
-
33750465224
-
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
-
Kawane, K. et al. Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443, 998-1002 (2006).
-
(2006)
Nature
, vol.443
, pp. 998-1002
-
-
Kawane, K.1
-
55
-
-
33744977003
-
Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway
-
Janssen, E. et al. Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway. Immunity 24, 787-799 (2006).
-
(2006)
Immunity
, vol.24
, pp. 787-799
-
-
Janssen, E.1
-
56
-
-
33846330896
-
Nod-like proteins in immunity, inflammation and disease
-
Fritz, J.H., Ferrero, R.L., Philpott, D.J. & Girardin, S.E. Nod-like proteins in immunity, inflammation and disease. Nat. Immunol. 7, 1250-1257 (2006).
-
(2006)
Nat. Immunol
, vol.7
, pp. 1250-1257
-
-
Fritz, J.H.1
Ferrero, R.L.2
Philpott, D.J.3
Girardin, S.E.4
-
57
-
-
0034036862
-
Apoptosis in systemic lupus erythematosus. Clinical implications
-
Andrade, F., Casciola-Rosen, L. & Rosen, A. Apoptosis in systemic lupus erythematosus. Clinical implications. Rheum. Dis. Clin. North Am. 26, 215-227, v (2000).
-
(2000)
Rheum. Dis. Clin. North Am
, vol.26
, pp. 215-227
-
-
Andrade, F.1
Casciola-Rosen, L.2
Rosen, A.3
-
58
-
-
33744971173
-
Inefficient clearance of dying cells and autoreactivity
-
Gaipl, U.S. et al. Inefficient clearance of dying cells and autoreactivity. Curr. Top. Microbiol. Immunol. 305, 161-176 (2006).
-
(2006)
Curr. Top. Microbiol. Immunol
, vol.305
, pp. 161-176
-
-
Gaipl, U.S.1
-
59
-
-
33644842388
-
Role of complement and other innate immune mechanisms in the removal of apoptotic cells
-
Ogden, C.A. & Elkon, K.B. Role of complement and other innate immune mechanisms in the removal of apoptotic cells. Curr. Dir. Autoimmun. 9, 120-142 (2006).
-
(2006)
Curr. Dir. Autoimmun
, vol.9
, pp. 120-142
-
-
Ogden, C.A.1
Elkon, K.B.2
-
60
-
-
0031778836
-
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
-
Botto, M. et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat. Genet. 19, 56-59 (1998).
-
(1998)
Nat. Genet
, vol.19
, pp. 56-59
-
-
Botto, M.1
-
61
-
-
0035854442
-
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
-
Lu, Q. & Lemke, G. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 293, 306-311 (2001).
-
(2001)
Science
, vol.293
, pp. 306-311
-
-
Lu, Q.1
Lemke, G.2
-
62
-
-
0031825552
-
Systemic exposure to irradiated apoptotic cells induces autoantibody production
-
Mevorach, D., Zhou, J.L., Song, X. & Elkon, K.B. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J. Exp. Med. 188, 387-392 (1998).
-
(1998)
J. Exp. Med
, vol.188
, pp. 387-392
-
-
Mevorach, D.1
Zhou, J.L.2
Song, X.3
Elkon, K.B.4
-
63
-
-
32044451586
-
Accelerated macrophage apoptosis induces autoantibody formation and organ damage in systemic lupus erythematosus
-
Denny, M.F. et al. Accelerated macrophage apoptosis induces autoantibody formation and organ damage in systemic lupus erythematosus. J. Immunol. 176, 2095-2104 (2006).
-
(2006)
J. Immunol
, vol.176
, pp. 2095-2104
-
-
Denny, M.F.1
-
64
-
-
33846784058
-
Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies
-
Takemura, Y. et al. Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J. Clin. Invest. 117, 375-386 (2007).
-
(2007)
J. Clin. Invest
, vol.117
, pp. 375-386
-
-
Takemura, Y.1
-
65
-
-
0032695108
-
Natural adjuvants: Endogenous activators of dendritic cells
-
Gallucci, S., Lolkema, M. & Matzinger, P. Natural adjuvants: endogenous activators of dendritic cells. Nat. Med. 5, 1249-1255 (1999).
-
(1999)
Nat. Med
, vol.5
, pp. 1249-1255
-
-
Gallucci, S.1
Lolkema, M.2
Matzinger, P.3
-
66
-
-
30444457915
-
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis
-
Winau, F. et al. Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis. Immunity 24, 105-117 (2006).
-
(2006)
Immunity
, vol.24
, pp. 105-117
-
-
Winau, F.1
-
67
-
-
0032485487
-
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
-
Albert, M.L., Sauter, B. & Bhardwaj, N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392, 86-89 (1998).
-
(1998)
Nature
, vol.392
, pp. 86-89
-
-
Albert, M.L.1
Sauter, B.2
Bhardwaj, N.3
-
68
-
-
33846057130
-
Calreticulin exposure dictates the immunogenicity of cancer cell death
-
Obeid, M. et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat. Med. 13, 54-61 (2007).
-
(2007)
Nat. Med
, vol.13
, pp. 54-61
-
-
Obeid, M.1
-
69
-
-
2142821465
-
Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease
-
Waldner, H., Collins, M. & Kuchroo, V.K. Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease. J. Clin. Invest. 113, 990-997 (2004).
-
(2004)
J. Clin. Invest
, vol.113
, pp. 990-997
-
-
Waldner, H.1
Collins, M.2
Kuchroo, V.K.3
-
70
-
-
20044385554
-
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
-
Lang, K.S. et al. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat. Med. 11, 138-145 (2005).
-
(2005)
Nat. Med
, vol.11
, pp. 138-145
-
-
Lang, K.S.1
-
71
-
-
33748296239
-
Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling
-
Lang, K.S. et al. Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling. J. Clin. Invest. 116, 2456-2463 (2006).
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2456-2463
-
-
Lang, K.S.1
-
72
-
-
10744228908
-
Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity
-
Eriksson, U. et al. Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity. Nat. Med. 9, 1484-1490 (2003).
-
(2003)
Nat. Med
, vol.9
, pp. 1484-1490
-
-
Eriksson, U.1
-
73
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg, A.M. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20, 709-760 (2002).
-
(2002)
Annu. Rev. Immunol
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
74
-
-
0344009684
-
Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer
-
Seya, T. et al. Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer. Anticancer Res. 23, 4369-4376 (2003).
-
(2003)
Anticancer Res
, vol.23
, pp. 4369-4376
-
-
Seya, T.1
-
75
-
-
33745115404
-
Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus
-
Poole, B.D., Scofield, R.H., Harley, J.B. & James, J.A. Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus. Autoimmunity 39, 63-70 (2006).
-
(2006)
Autoimmunity
, vol.39
, pp. 63-70
-
-
Poole, B.D.1
Scofield, R.H.2
Harley, J.B.3
James, J.A.4
-
76
-
-
85133362161
-
-
Pawar, R.D., Patole, P.S., Wornle, M. & Anders, H.J. Microbial nucleic acids pay a Toll in kidney disease. Am. J. Physiol. Renal Physiol. 291, F509-F516 (2006).
-
Pawar, R.D., Patole, P.S., Wornle, M. & Anders, H.J. Microbial nucleic acids pay a Toll in kidney disease. Am. J. Physiol. Renal Physiol. 291, F509-F516 (2006).
-
-
-
-
77
-
-
14044278824
-
IFN- induces early lethal lupus in preautoimmune (New Zealand Black x New Zealand White) F1 but not in BALB/c mice
-
Mathian, A., Weinberg, A., Gallegos, M., Banchereau, J. & Koutouzov, S. IFN- induces early lethal lupus in preautoimmune (New Zealand Black x New Zealand White) F1 but not in BALB/c mice. J. Immunol. 174, 2499-2506 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 2499-2506
-
-
Mathian, A.1
Weinberg, A.2
Gallegos, M.3
Banchereau, J.4
Koutouzov, S.5
-
78
-
-
0141886220
-
IFN- skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities
-
Mohty, M. et al. IFN- skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities. J. Immunol. 171, 3385-3393 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 3385-3393
-
-
Mohty, M.1
-
79
-
-
15444364398
-
Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN
-
Bekeredjian-Ding, I.B. et al. Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN. J. Immunol. 174, 4043-4050 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 4043-4050
-
-
Bekeredjian-Ding, I.B.1
-
80
-
-
0020639832
-
Induction of murine autoimmune disease by chronic polyclonal B cell activation
-
Hang, L. et al. Induction of murine autoimmune disease by chronic polyclonal B cell activation. J. Exp. Med. 157, 874-883 (1983).
-
(1983)
J. Exp. Med
, vol.157
, pp. 874-883
-
-
Hang, L.1
-
81
-
-
22944490869
-
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
-
Christensen, S.R. et al. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J. Exp. Med. 202, 321-331 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 321-331
-
-
Christensen, S.R.1
-
82
-
-
33645076274
-
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
-
Ehlers, M., Fukuyama, H., McGaha, T.L., Aderem, A. & Ravetch, J.V. TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. J. Exp. Med. 203, 553-561 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 553-561
-
-
Ehlers, M.1
Fukuyama, H.2
McGaha, T.L.3
Aderem, A.4
Ravetch, J.V.5
-
83
-
-
31044440025
-
Toll-like receptor 9 signaling protects against murine lupus
-
Wu, X. & Peng, S.L. Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum. 54, 336-342 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 336-342
-
-
Wu, X.1
Peng, S.L.2
-
84
-
-
33745864016
-
Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus
-
Lartigue, A. et al. Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus. J. Immunol. 177, 1349-1354 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 1349-1354
-
-
Lartigue, A.1
-
85
-
-
33748465308
-
Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE
-
Yu, P. et al. Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE. Int. Immunol. 18, 1211-1219 (2006).
-
(2006)
Int. Immunol
, vol.18
, pp. 1211-1219
-
-
Yu, P.1
-
86
-
-
33748472865
-
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
-
Christensen, S.R. et al. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25, 417-428 (2006).
-
(2006)
Immunity
, vol.25
, pp. 417-428
-
-
Christensen, S.R.1
-
87
-
-
3242736779
-
Lupus glomerulonephritis revisited 2004: Autoimmunity and end-organ damage
-
Bagavant, H., Deshmukh, U.S., Gaskin, F. & Fu, S.M. Lupus glomerulonephritis revisited 2004: autoimmunity and end-organ damage. Scand. J. Immunol. 60, 52-63 (2004).
-
(2004)
Scand. J. Immunol
, vol.60
, pp. 52-63
-
-
Bagavant, H.1
Deshmukh, U.S.2
Gaskin, F.3
Fu, S.M.4
-
88
-
-
0025905663
-
Natural autoantibodies: From 'horror autotoxicus' to 'gnothi seauton'
-
Avrameas, S. Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'. Immunol. Today 12, 154-159 (1991).
-
(1991)
Immunol. Today
, vol.12
, pp. 154-159
-
-
Avrameas, S.1
-
89
-
-
27744444832
-
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
-
Lau, C.M. et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J. Exp. Med. 202, 1171-1177 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1171-1177
-
-
Lau, C.M.1
-
90
-
-
33748470505
-
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice
-
Berland, R. et al. Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. Immunity 25, 429-440 (2006).
-
(2006)
Immunity
, vol.25
, pp. 429-440
-
-
Berland, R.1
-
91
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun, P. et al. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 312, 1669-1672 (2006).
-
(2006)
Science
, vol.312
, pp. 1669-1672
-
-
Pisitkun, P.1
-
92
-
-
33745617886
-
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
-
Subramanian, S. et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc. Natl. Acad. Sci. USA 103, 9970-9975 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9970-9975
-
-
Subramanian, S.1
-
93
-
-
31344466165
-
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
-
Tabeta, K. et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat. Immunol. 7, 156-164 (2006).
-
(2006)
Nat. Immunol
, vol.7
, pp. 156-164
-
-
Tabeta, K.1
-
94
-
-
0033153482
-
The role of environmental antigens in the spontaneous development of autoimmunity in MRL-lpr mice
-
Maldonado, M.A. et al. The role of environmental antigens in the spontaneous development of autoimmunity in MRL-lpr mice. J. Immunol. 162, 6322-6330 (1999).
-
(1999)
J. Immunol
, vol.162
, pp. 6322-6330
-
-
Maldonado, M.A.1
-
95
-
-
13444302229
-
Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice
-
Dong, L., Ito, S., Ishii, K.J. & Klinman, D.M. Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice. Arthritis Rheum. 52, 651-658 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 651-658
-
-
Dong, L.1
Ito, S.2
Ishii, K.J.3
Klinman, D.M.4
-
96
-
-
33646478589
-
Therapeutic targeting of pattern-recognition receptors
-
Rezaei, N. Therapeutic targeting of pattern-recognition receptors. Int. Immunopharmacol. 6, 863-869 (2006).
-
(2006)
Int. Immunopharmacol
, vol.6
, pp. 863-869
-
-
Rezaei, N.1
-
97
-
-
33646459191
-
Mechanisms of disease: Primary Sjogren's syndrome and the type I interferon system
-
Nordmark, G., Alm, G.V. & Ronnblom, L. Mechanisms of disease: primary Sjogren's syndrome and the type I interferon system. Nat. Clin. Pract. Rheumatol. 2, 262-269 (2006).
-
(2006)
Nat. Clin. Pract. Rheumatol
, vol.2
, pp. 262-269
-
-
Nordmark, G.1
Alm, G.V.2
Ronnblom, L.3
-
98
-
-
0037379578
-
Neutralizing interferon as a therapeutic approach to autoimmune diseases
-
Stewart, T.A. Neutralizing interferon as a therapeutic approach to autoimmune diseases. Cytokine Growth Factor Rev. 14, 139-154 (2003).
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, pp. 139-154
-
-
Stewart, T.A.1
-
99
-
-
22344438901
-
Plasmacytoid predendritic cells initiate psoriasis through interferon- production
-
Nestle, F.O. et al. Plasmacytoid predendritic cells initiate psoriasis through interferon- production. J. Exp. Med. 202, 135-143 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 135-143
-
-
Nestle, F.O.1
-
100
-
-
33744475615
-
+ lymphocytes in dermatomyositis
-
+ lymphocytes in dermatomyositis. Clin. Exp. Dermatol. 31, 576-582 (2006).
-
(2006)
Clin. Exp. Dermatol
, vol.31
, pp. 576-582
-
-
Wenzel, J.1
-
101
-
-
33750542135
-
Toll' gates for future immunotherapy
-
Ishii, K.J., Uematsu, S. & Akira, S. 'Toll' gates for future immunotherapy. Curr. Pharm. Des. 12, 4135-4142 (2006).
-
(2006)
Curr. Pharm. Des
, vol.12
, pp. 4135-4142
-
-
Ishii, K.J.1
Uematsu, S.2
Akira, S.3
|