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Volumn 79, Issue , 2007, Pages 589-620

Remyelination In Multiple Sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BIOLOGICAL MODEL; DISEASE MODEL; HUMAN; MULTIPLE SCLEROSIS; MYELIN SHEATH; NERVE REGENERATION; OLIGODENDROGLIA; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

EID: 34248657276     PISSN: 00747742     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0074-7742(07)79026-8     Document Type: Review
Times cited : (99)

References (147)
  • 3
  • 4
    • 0242524481 scopus 로고    scopus 로고
    • Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration
    • Arnett H.A., Wang Y., Matsushima G.K., Suzuki K., and Ting J.P. Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. J. Neurosci. 23 (2003) 9824-9832
    • (2003) J. Neurosci. , vol.23 , pp. 9824-9832
    • Arnett, H.A.1    Wang, Y.2    Matsushima, G.K.3    Suzuki, K.4    Ting, J.P.5
  • 8
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett M.H., and Prineas J.W. Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion. Ann. Neurol. 55 (2004) 458-468
    • (2004) Ann. Neurol. , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 9
    • 1642423484 scopus 로고    scopus 로고
    • Olfactory ensheathing cells (OECs) and the treatment of CNS injury: Advantages and possible caveats
    • Review
    • Barnett S.C., and Riddell J.S. Olfactory ensheathing cells (OECs) and the treatment of CNS injury: Advantages and possible caveats. J. Anat. 204 (2004) 57-67 Review
    • (2004) J. Anat. , vol.204 , pp. 57-67
    • Barnett, S.C.1    Riddell, J.S.2
  • 10
    • 0034636493 scopus 로고    scopus 로고
    • Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus
    • Bergles D.E., Bergles D.E., Roberts J.D., Somogyi P., and Jahr C.E. Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus. Nature 405 (2000) 187-191
    • (2000) Nature , vol.405 , pp. 187-191
    • Bergles, D.E.1    Bergles, D.E.2    Roberts, J.D.3    Somogyi, P.4    Jahr, C.E.5
  • 11
    • 0038077547 scopus 로고    scopus 로고
    • Efficient central nervous system remyelination requires T cells
    • Bieber A.J., Kerr S., and Rodriguez M. Efficient central nervous system remyelination requires T cells. Ann. Neurol. 53 (2003) 680-684
    • (2003) Ann. Neurol. , vol.53 , pp. 680-684
    • Bieber, A.J.1    Kerr, S.2    Rodriguez, M.3
  • 12
    • 33646253436 scopus 로고    scopus 로고
    • Remyelination of dorsal column axons by endogenous Schwann cells restores the normal pattern of Nav1. 6 and Kv1. 2 at nodes of Ranvier
    • Black J.A., Waxman S.G., and Smith K.J. Remyelination of dorsal column axons by endogenous Schwann cells restores the normal pattern of Nav1. 6 and Kv1. 2 at nodes of Ranvier. Brain 129 (2006) 1319-1329
    • (2006) Brain , vol.129 , pp. 1319-1329
    • Black, J.A.1    Waxman, S.G.2    Smith, K.J.3
  • 13
    • 13544275545 scopus 로고    scopus 로고
    • The case for a central nervous system (CNS) origin for the Schwann cells that remyelinate CNS axons following concurrent loss of oligodendrocytes and astrocytes
    • Blakemore W.F. The case for a central nervous system (CNS) origin for the Schwann cells that remyelinate CNS axons following concurrent loss of oligodendrocytes and astrocytes. Neuropathol. Appl. Neurobiol. 31 (2005) 1-10
    • (2005) Neuropathol. Appl. Neurobiol. , vol.31 , pp. 1-10
    • Blakemore, W.F.1
  • 14
    • 0018124172 scopus 로고
    • Suppression of remyelination in the CNS by X-irradiation
    • Blakemore W.F., and Patterson R.C. Suppression of remyelination in the CNS by X-irradiation. Acta Neuropathol. Berl. 42 (1978) 105-113
    • (1978) Acta Neuropathol. Berl. , vol.42 , pp. 105-113
    • Blakemore, W.F.1    Patterson, R.C.2
  • 15
    • 0037089096 scopus 로고    scopus 로고
    • Modelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS
    • Blakemore W.F., Chari D.M., Gilson J.M., and Crang A.J. Modelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS. Glia 15 (2002) 155-168
    • (2002) Glia , vol.15 , pp. 155-168
    • Blakemore, W.F.1    Chari, D.M.2    Gilson, J.M.3    Crang, A.J.4
  • 16
    • 0842342523 scopus 로고    scopus 로고
    • The presence of astrocytes in areas of demyelination influences remyelination following transplantation of oligodendrocyte progenitors
    • Blakemore W.F., Gilson J.M., and Crang A.J. The presence of astrocytes in areas of demyelination influences remyelination following transplantation of oligodendrocyte progenitors. Exp. Neurol. 184 (2003) 955-963
    • (2003) Exp. Neurol. , vol.184 , pp. 955-963
    • Blakemore, W.F.1    Gilson, J.M.2    Crang, A.J.3
  • 19
    • 0001918961 scopus 로고
    • Ultrastructural study of remyelination in an experimental lesion in adult cat spinal cord
    • Bunge M.B., Bunge R.P., and Ris H. Ultrastructural study of remyelination in an experimental lesion in adult cat spinal cord. J. Biophys. Biochem. Cytol. 10 (1961) 67-94
    • (1961) J. Biophys. Biochem. Cytol. , vol.10 , pp. 67-94
    • Bunge, M.B.1    Bunge, R.P.2    Ris, H.3
  • 20
    • 34248646609 scopus 로고
    • Regenerative phenomena in the feline spinal cord in late stages of lesions inflicted by cerebrospinal fluid manipulation
    • Bunge R.P. Regenerative phenomena in the feline spinal cord in late stages of lesions inflicted by cerebrospinal fluid manipulation. Anat. Rec. 130 (1958) 279
    • (1958) Anat. Rec. , vol.130 , pp. 279
    • Bunge, R.P.1
  • 21
    • 0007541365 scopus 로고
    • Neurological lesions in cats following cerebrospinal fluid manipulation
    • Bunge R.P., and Settlage P.H. Neurological lesions in cats following cerebrospinal fluid manipulation. J. Neuropathol. Exp. Neurol. 16 (1957) 471-491
    • (1957) J. Neuropathol. Exp. Neurol. , vol.16 , pp. 471-491
    • Bunge, R.P.1    Settlage, P.H.2
  • 22
    • 0033103253 scopus 로고    scopus 로고
    • Cells expressing the NG2 antigen contact nodes of Ranvier in adult CNS white matter
    • Butt A.M., Duncan A., Hornby M.F., Kirvell S.L., Hunter A., Levine J.M., and Berry M. Cells expressing the NG2 antigen contact nodes of Ranvier in adult CNS white matter. Glia 26 (1999) 84-91
    • (1999) Glia , vol.26 , pp. 84-91
    • Butt, A.M.1    Duncan, A.2    Hornby, M.F.3    Kirvell, S.L.4    Hunter, A.5    Levine, J.M.6    Berry, M.7
  • 25
    • 0027269766 scopus 로고
    • Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice
    • Carson M.J., Behringer R.R., Brinster R.L., and McMorris F.A. Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron 10 (1993) 729-740
    • (1993) Neuron , vol.10 , pp. 729-740
    • Carson, M.J.1    Behringer, R.R.2    Brinster, R.L.3    McMorris, F.A.4
  • 26
    • 0034281366 scopus 로고    scopus 로고
    • NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions
    • Chang A., Nishiyama A., Peterson J., Prineas J., and Trapp B.D. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J. Neurosci. 20 (2000) 6404-6412
    • (2000) J. Neurosci. , vol.20 , pp. 6404-6412
    • Chang, A.1    Nishiyama, A.2    Peterson, J.3    Prineas, J.4    Trapp, B.D.5
  • 27
    • 0037122960 scopus 로고    scopus 로고
    • Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis
    • Chang A., Tourtellotte W.W., Rudick R., and Trapp B.D. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N. Engl. J. Med. 346 (2002) 165-173
    • (2002) N. Engl. J. Med. , vol.346 , pp. 165-173
    • Chang, A.1    Tourtellotte, W.W.2    Rudick, R.3    Trapp, B.D.4
  • 28
    • 0037085715 scopus 로고    scopus 로고
    • Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cells
    • Chari D.M., and Blakemore W.F. Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cells. Glia 37 (2002) 307-313
    • (2002) Glia , vol.37 , pp. 307-313
    • Chari, D.M.1    Blakemore, W.F.2
  • 29
    • 0035996192 scopus 로고    scopus 로고
    • New insights into remyelination failure in multiple sclerosis: Implications for glial cell transplantation
    • Review
    • Chari D.M., and Blakemore W.F. New insights into remyelination failure in multiple sclerosis: Implications for glial cell transplantation. Mult. Scler. 8 (2002) 271-277 Review
    • (2002) Mult. Scler. , vol.8 , pp. 271-277
    • Chari, D.M.1    Blakemore, W.F.2
  • 30
    • 0141566761 scopus 로고    scopus 로고
    • Decline in rate of colonization of oligodendrocyte progenitor cell (OPC)-depleted tissue by adult OPCs with age
    • Chari D.M., Crang A.J., and Blakemore W.F. Decline in rate of colonization of oligodendrocyte progenitor cell (OPC)-depleted tissue by adult OPCs with age. J. Neuropathol. Exp. Neurol. 62 (2003) 908-916
    • (2003) J. Neuropathol. Exp. Neurol. , vol.62 , pp. 908-916
    • Chari, D.M.1    Crang, A.J.2    Blakemore, W.F.3
  • 31
    • 0042338685 scopus 로고    scopus 로고
    • Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue
    • Chari D.M., Huang W.L., and Blakemore W.F. Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue. J. Neurosci. Res. 73 (2003) 787-793
    • (2003) J. Neurosci. Res. , vol.73 , pp. 787-793
    • Chari, D.M.1    Huang, W.L.2    Blakemore, W.F.3
  • 32
    • 33644931322 scopus 로고    scopus 로고
    • Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system
    • Chari D.M., Zhao C., Kotter M.R., Blakemore W.F., and Franklin R.J. Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system. J. Neurosci. Res. 83 (2006) 594-605
    • (2006) J. Neurosci. Res. , vol.83 , pp. 594-605
    • Chari, D.M.1    Zhao, C.2    Kotter, M.R.3    Blakemore, W.F.4    Franklin, R.J.5
  • 33
    • 32644436264 scopus 로고    scopus 로고
    • Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS
    • Chari D.M., Gilson J.M., Franklin R.J., and Blakemore W.F. Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS. Exp. Neurol. 198 (2006) 145-153
    • (2006) Exp. Neurol. , vol.198 , pp. 145-153
    • Chari, D.M.1    Gilson, J.M.2    Franklin, R.J.3    Blakemore, W.F.4
  • 34
    • 18744409058 scopus 로고    scopus 로고
    • Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses
    • Review
    • Christensen T. Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses. Rev. Med. Virol. 15 (2005) 179-211 Review
    • (2005) Rev. Med. Virol. , vol.15 , pp. 179-211
    • Christensen, T.1
  • 35
    • 20444409146 scopus 로고    scopus 로고
    • Axonal signals in central nervous system myelination, demyelination and remyelination
    • Review
    • Coman I., Barbin G., Charles P., Zalc B., and Lubetzki C. Axonal signals in central nervous system myelination, demyelination and remyelination. J. Neurol. Sci. 233 (2005) 67-71 Review
    • (2005) J. Neurol. Sci. , vol.233 , pp. 67-71
    • Coman, I.1    Barbin, G.2    Charles, P.3    Zalc, B.4    Lubetzki, C.5
  • 36
    • 4143102903 scopus 로고    scopus 로고
    • The remyelinating potential and in vitro differentiation of MOG-expressing oligodendrocyte precursors isolated from the adult rat CNS
    • Crang A.J., Gilson J.M., Li W.W., and Blakemore W.F. The remyelinating potential and in vitro differentiation of MOG-expressing oligodendrocyte precursors isolated from the adult rat CNS. Eur. J. Neurosci. 20 (2004) 1445-1460
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1445-1460
    • Crang, A.J.1    Gilson, J.M.2    Li, W.W.3    Blakemore, W.F.4
  • 37
    • 13244277548 scopus 로고    scopus 로고
    • Number of oligodendrocyte progenitors recruited to the lesioned spinal cord is modulated by the levels of the cell cycle regulatory protein p27Kip-1
    • Crockett D.P., Burshteyn M., Garcia C., Muggironi M., and Casaccia-Bonnefil P. Number of oligodendrocyte progenitors recruited to the lesioned spinal cord is modulated by the levels of the cell cycle regulatory protein p27Kip-1. Glia 49 (2005) 301-308
    • (2005) Glia , vol.49 , pp. 301-308
    • Crockett, D.P.1    Burshteyn, M.2    Garcia, C.3    Muggironi, M.4    Casaccia-Bonnefil, P.5
  • 39
    • 25644434410 scopus 로고    scopus 로고
    • Enhancing central nervous system remyelination in multiple sclerosis
    • Review
    • Dubois-Dalcq M., Ffrench-Constant C., and Franklin R.J. Enhancing central nervous system remyelination in multiple sclerosis. Neuron 48 (2005) 9-12 Review
    • (2005) Neuron , vol.48 , pp. 9-12
    • Dubois-Dalcq, M.1    Ffrench-Constant, C.2    Franklin, R.J.3
  • 40
    • 0028800495 scopus 로고
    • Clustering of Na+ channels and node of Ranvier formation in remyelinating axons
    • Dugandzija-Novakovic S., Koszowski A.G., Levinson S.R., and Shrager P. Clustering of Na+ channels and node of Ranvier formation in remyelinating axons. J. Neurosci. 15 (1995) 492-503
    • (1995) J. Neurosci. , vol.15 , pp. 492-503
    • Dugandzija-Novakovic, S.1    Koszowski, A.G.2    Levinson, S.R.3    Shrager, P.4
  • 41
    • 33644817144 scopus 로고    scopus 로고
    • Remyelination and restoration of axonal function by glial cell transplantation
    • Review
    • Duncan I.D. Remyelination and restoration of axonal function by glial cell transplantation. Ernst Schering Res. Found. Workshop 53 (2005) 115-132 Review
    • (2005) Ernst Schering Res. Found. Workshop , vol.53 , pp. 115-132
    • Duncan, I.D.1
  • 42
    • 0033957316 scopus 로고    scopus 로고
    • A cell-intrinsic timer that operates during oligodendrocyte development
    • Review
    • Durand B., and Raff M. A cell-intrinsic timer that operates during oligodendrocyte development. Bioessays 22 (2000) 64-71 Review
    • (2000) Bioessays , vol.22 , pp. 64-71
    • Durand, B.1    Raff, M.2
  • 44
    • 33644836341 scopus 로고    scopus 로고
    • Mechanisms of immunopathology in murine models of central nervous system demyelinating disease
    • Review
    • Ercolini A.M., and Miller S.D. Mechanisms of immunopathology in murine models of central nervous system demyelinating disease. J. Immunol. 176 (2006) 3293-3298 Review
    • (2006) J. Immunol. , vol.176 , pp. 3293-3298
    • Ercolini, A.M.1    Miller, S.D.2
  • 45
    • 7244226354 scopus 로고    scopus 로고
    • Increased expression of Nkx2. 2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS
    • Fancy S.P., Zhao C., and Franklin R.J. Increased expression of Nkx2. 2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. Mol. Cell. Neurosci. 27 (2004) 247-254
    • (2004) Mol. Cell. Neurosci. , vol.27 , pp. 247-254
    • Fancy, S.P.1    Zhao, C.2    Franklin, R.J.3
  • 46
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in multiple sclerosis lesions
    • Ferguson B., Matyszak M.K., Esiri M.M., and Perry V.H. Axonal damage in multiple sclerosis lesions. Brain 120 (1997) 393-399
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 47
    • 15044357461 scopus 로고    scopus 로고
    • Inflammation stimulates remyelination in areas of chronic demyelination
    • Foote A.K., and Blakemore W.F. Inflammation stimulates remyelination in areas of chronic demyelination. Brain 128 (2005) 528-539
    • (2005) Brain , vol.128 , pp. 528-539
    • Foote, A.K.1    Blakemore, W.F.2
  • 48
    • 0036720034 scopus 로고    scopus 로고
    • Why does remyelination fail in multiple sclerosis?
    • Review
    • Franklin R.J. Why does remyelination fail in multiple sclerosis?. Nat. Rev. Neurosci. 3 (2002) 705-714 Review
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 705-714
    • Franklin, R.J.1
  • 49
    • 0033569751 scopus 로고    scopus 로고
    • Understanding CNS remyelination: Clues from developmental and regeneration biology
    • Review
    • Franklin R.J., and Hinks G.L. Understanding CNS remyelination: Clues from developmental and regeneration biology. J. Neurosci. Res 58 (1999) 207-213 Review
    • (1999) J. Neurosci. Res , vol.58 , pp. 207-213
    • Franklin, R.J.1    Hinks, G.L.2
  • 50
    • 0029873034 scopus 로고    scopus 로고
    • Transplanted CG4 cells (an oligodendrocyte progenitor cell line) survive, migrate, and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cord
    • Franklin R.J., Bayley S.A., and Blakemore W.F. Transplanted CG4 cells (an oligodendrocyte progenitor cell line) survive, migrate, and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cord. Exp. Neurol. 137 (1996) 263-276
    • (1996) Exp. Neurol. , vol.137 , pp. 263-276
    • Franklin, R.J.1    Bayley, S.A.2    Blakemore, W.F.3
  • 51
    • 0027495887 scopus 로고
    • Requirements for Schwann cell migration within CNS environments: A viewpoint
    • Franklin R.J.M., and Blakemore W.F. Requirements for Schwann cell migration within CNS environments: A viewpoint. Int. J. Dev. Neurosci. 11 (1993) 641-649
    • (1993) Int. J. Dev. Neurosci. , vol.11 , pp. 641-649
    • Franklin, R.J.M.1    Blakemore, W.F.2
  • 52
    • 0025765227 scopus 로고
    • Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord
    • Franklin R.J.M., Crang A.J., and Blakemore W.F. Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord. J. Neurocytol. 20 (1991) 420-430
    • (1991) J. Neurocytol. , vol.20 , pp. 420-430
    • Franklin, R.J.M.1    Crang, A.J.2    Blakemore, W.F.3
  • 53
    • 0037441499 scopus 로고    scopus 로고
    • PDGF and FGF2 regulate oligodendrocyte progenitor responses to demyelination
    • Frost E.E., Nielsen J.A., Le T.Q., and Armstrong R.C. PDGF and FGF2 regulate oligodendrocyte progenitor responses to demyelination. J. Neurobiol. 54 (2003) 457-472
    • (2003) J. Neurobiol. , vol.54 , pp. 457-472
    • Frost, E.E.1    Nielsen, J.A.2    Le, T.Q.3    Armstrong, R.C.4
  • 55
    • 26444440785 scopus 로고    scopus 로고
    • The role of ion channels and neurotransmitter receptors in glial cell development
    • Jessen K.R., and Richardson W.D. (Eds), Oxford University Press, New York
    • Gallo V., Ghiani C.A., and Yuan X. The role of ion channels and neurotransmitter receptors in glial cell development. In: Jessen K.R., and Richardson W.D. (Eds). "Glial Cell Development" (2001), Oxford University Press, New York 109-130
    • (2001) "Glial Cell Development" , pp. 109-130
    • Gallo, V.1    Ghiani, C.A.2    Yuan, X.3
  • 58
    • 0027157685 scopus 로고
    • Failure of remyelination in areas of demyelination produced in the spinal cord of old rats
    • Gilson J., and Blakemore W.F. Failure of remyelination in areas of demyelination produced in the spinal cord of old rats. Neuropathol. Appl. Neurobiol. 19 (1993) 173-181
    • (1993) Neuropathol. Appl. Neurobiol. , vol.19 , pp. 173-181
    • Gilson, J.1    Blakemore, W.F.2
  • 59
    • 0022921616 scopus 로고
    • Delayed remyelination in the rat spinal cord following ethidium bromide injection
    • Graca D.L., and Blakemore W.F. Delayed remyelination in the rat spinal cord following ethidium bromide injection. Neuropathol. Appl. Neurobiol. 12 (1986) 593-605
    • (1986) Neuropathol. Appl. Neurobiol. , vol.12 , pp. 593-605
    • Graca, D.L.1    Blakemore, W.F.2
  • 62
    • 0033045774 scopus 로고    scopus 로고
    • Insulin-like growth factors and binding proteins in multiple sclerosis plaques
    • Gveric D., Cuzner M.L., and Newcombe J. Insulin-like growth factors and binding proteins in multiple sclerosis plaques. Neuropathol. Appl. Neurobiol. 25 (1999) 215-225
    • (1999) Neuropathol. Appl. Neurobiol. , vol.25 , pp. 215-225
    • Gveric, D.1    Cuzner, M.L.2    Newcombe, J.3
  • 63
    • 0036546066 scopus 로고    scopus 로고
    • New concepts in the immunopathogenesis of multiple sclerosis
    • Review
    • Hemmer B., Archelos J.J., and Hartung H.P. New concepts in the immunopathogenesis of multiple sclerosis. Nat. Rev. Neurosci. 3 (2002) 291-301 Review
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 291-301
    • Hemmer, B.1    Archelos, J.J.2    Hartung, H.P.3
  • 64
    • 0032830744 scopus 로고    scopus 로고
    • Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination
    • Hinks G.L., and Franklin R.J.M. Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination. Mol. Cell. Neurosci. 14 (1999) 153-168
    • (1999) Mol. Cell. Neurosci. , vol.14 , pp. 153-168
    • Hinks, G.L.1    Franklin, R.J.M.2
  • 65
    • 33646341818 scopus 로고    scopus 로고
    • Olfactory ensheathing cells: Ripples of an incoming tide?
    • Review
    • Ibrahim A., Li Y., Li D., Raisman G., and El Masry W.S. Olfactory ensheathing cells: Ripples of an incoming tide?. Lancet Neurol. 5 (2006) 453-457 Review
    • (2006) Lancet Neurol. , vol.5 , pp. 453-457
    • Ibrahim, A.1    Li, Y.2    Li, D.3    Raisman, G.4    El Masry, W.S.5
  • 66
    • 0020516765 scopus 로고
    • Schwann cell remyelination of demyelinated axons in spinal cord multiple sclerosis lesions
    • Itoyama Y., Webster H.D., Richardson E.P., and Trapp B.D. Schwann cell remyelination of demyelinated axons in spinal cord multiple sclerosis lesions. Ann. Neurol. 14 (1983) 339-346
    • (1983) Ann. Neurol. , vol.14 , pp. 339-346
    • Itoyama, Y.1    Webster, H.D.2    Richardson, E.P.3    Trapp, B.D.4
  • 67
    • 0021968643 scopus 로고
    • Spinal cord multiple sclerosis lesions in Japanese patients: Schwann cell remyelination occurs in areas that lack glial fibrillary acidic protein (GFAP)
    • Itoyama Y., Ohnishi A., Tateishi J., Kuroiwa Y., and Webster H.D. Spinal cord multiple sclerosis lesions in Japanese patients: Schwann cell remyelination occurs in areas that lack glial fibrillary acidic protein (GFAP). Acta Neuropathol. (Berl.) 65 (1985) 217-223
    • (1985) Acta Neuropathol. (Berl.) , vol.65 , pp. 217-223
    • Itoyama, Y.1    Ohnishi, A.2    Tateishi, J.3    Kuroiwa, Y.4    Webster, H.D.5
  • 68
    • 0031050183 scopus 로고    scopus 로고
    • Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination
    • Jeffery N.D., and Blakemore W.F. Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination. Brain 120 (1997) 27-37
    • (1997) Brain , vol.120 , pp. 27-37
    • Jeffery, N.D.1    Blakemore, W.F.2
  • 69
    • 0036799650 scopus 로고    scopus 로고
    • Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation
    • John G.R., Shankar S.L., Shafit-Zagardo B., Massimi A., Lee S.C., Raine C.S., and Brosnan C.F. Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat. Med. 8 (2002) 1115-1121
    • (2002) Nat. Med. , vol.8 , pp. 1115-1121
    • John, G.R.1    Shankar, S.L.2    Shafit-Zagardo, B.3    Massimi, A.4    Lee, S.C.5    Raine, C.S.6    Brosnan, C.F.7
  • 70
    • 0027420450 scopus 로고
    • Visual evoked potentials after optic neuritis. Effect of time interval, age and disease dissemination
    • Jones S.J. Visual evoked potentials after optic neuritis. Effect of time interval, age and disease dissemination. J. Neurol. 240 (1993) 489-494
    • (1993) J. Neurol. , vol.240 , pp. 489-494
    • Jones, S.J.1
  • 71
    • 28444492982 scopus 로고    scopus 로고
    • Inhibition of Notch signaling enhances tissue repair in an animal model of multiple sclerosis
    • Jurynczyk M., Jurewicz A., Bielecki B., Raine C.S., and Selmaj K. Inhibition of Notch signaling enhances tissue repair in an animal model of multiple sclerosis. J. Neuroimmunol. 170 (2005) 3-10
    • (2005) J. Neuroimmunol. , vol.170 , pp. 3-10
    • Jurynczyk, M.1    Jurewicz, A.2    Bielecki, B.3    Raine, C.S.4    Selmaj, K.5
  • 72
    • 27844539332 scopus 로고    scopus 로고
    • Stem cells for the treatment of myelin loss
    • Keirstead H.S. Stem cells for the treatment of myelin loss. Trends Neurosci. 28 (2005) 677-683
    • (2005) Trends Neurosci. , vol.28 , pp. 677-683
    • Keirstead, H.S.1
  • 73
    • 0030785547 scopus 로고    scopus 로고
    • Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord
    • Keirstead H.S., and Blakemore W.F. Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord. J. Neuropathol. Exp. Neurol. 56 (1997) 1191-1201
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 1191-1201
    • Keirstead, H.S.1    Blakemore, W.F.2
  • 74
    • 0032005795 scopus 로고    scopus 로고
    • Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord
    • Keirstead H.S., Levine J.M., and Blakemore W.F. Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord. Glia 22 (1998) 161-170
    • (1998) Glia , vol.22 , pp. 161-170
    • Keirstead, H.S.1    Levine, J.M.2    Blakemore, W.F.3
  • 75
    • 1642375528 scopus 로고    scopus 로고
    • Targeting experimental autoimmune encephalomyelitis lesions to a predetermined axonal tract system allows for refined behavioral testing in an animal model of multiple sclerosis
    • Kerschensteiner M., Stadelmann C., Buddeberg B.S., Merkler D., Bareyre F.M., Anthony D.C., Linington C., Bruck W., and Schwab M.E. Targeting experimental autoimmune encephalomyelitis lesions to a predetermined axonal tract system allows for refined behavioral testing in an animal model of multiple sclerosis. Am. J. Pathol. 164 (2004) 1455-1469
    • (2004) Am. J. Pathol. , vol.164 , pp. 1455-1469
    • Kerschensteiner, M.1    Stadelmann, C.2    Buddeberg, B.S.3    Merkler, D.4    Bareyre, F.M.5    Anthony, D.C.6    Linington, C.7    Bruck, W.8    Schwab, M.E.9
  • 76
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • Kornek B., Storch M.K., Weissert R., Wallstroem E., Stefferl A., Olsson T., Linington C., Schmidbauer M., and Lassmann H. Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am. J. Pathol. 157 (2000) 267-276
    • (2000) Am. J. Pathol. , vol.157 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3    Wallstroem, E.4    Stefferl, A.5    Olsson, T.6    Linington, C.7    Schmidbauer, M.8    Lassmann, H.9
  • 77
    • 0034846364 scopus 로고    scopus 로고
    • Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination
    • Kotter M.R., Setzu A., Sim F.J., Van Rooijen N., and Franklin R.J.M. Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination. Glia 35 (2001) 204-212
    • (2001) Glia , vol.35 , pp. 204-212
    • Kotter, M.R.1    Setzu, A.2    Sim, F.J.3    Van Rooijen, N.4    Franklin, R.J.M.5
  • 78
    • 11844253894 scopus 로고    scopus 로고
    • Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression
    • Kotter M.R., Zhao C., van Rooijen N., and Franklin R.J. Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol. Dis. 18 (2005) 166-175
    • (2005) Neurobiol. Dis. , vol.18 , pp. 166-175
    • Kotter, M.R.1    Zhao, C.2    van Rooijen, N.3    Franklin, R.J.4
  • 82
    • 0036793758 scopus 로고    scopus 로고
    • Oligodendrocyte progenitor cells in the adult rat CNS express myelin oligodendrocyte glycoprotein (MOG)
    • Li G., Crang A.J., Rundle J.L., and Blakemore W.F. Oligodendrocyte progenitor cells in the adult rat CNS express myelin oligodendrocyte glycoprotein (MOG). Brain pathol. 12 (2002) 463-471
    • (2002) Brain pathol. , vol.12 , pp. 463-471
    • Li, G.1    Crang, A.J.2    Rundle, J.L.3    Blakemore, W.F.4
  • 83
    • 33748437057 scopus 로고    scopus 로고
    • Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS
    • Li W.W., Penderis J., Zhao C., Schumacher M., and Franklin R.J. Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS. Exp. Neurol. 202 (2006) 250-254
    • (2006) Exp. Neurol. , vol.202 , pp. 250-254
    • Li, W.W.1    Penderis, J.2    Zhao, C.3    Schumacher, M.4    Franklin, R.J.5
  • 84
    • 10344230955 scopus 로고    scopus 로고
    • Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination
    • Li W.W., Setzu A., Zhao C., and Franklin R.J.M. Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination. J. Neuroimmunol. 158 (2005) 58-66
    • (2005) J. Neuroimmunol. , vol.158 , pp. 58-66
    • Li, W.W.1    Setzu, A.2    Zhao, C.3    Franklin, R.J.M.4
  • 86
    • 0342288638 scopus 로고    scopus 로고
    • Axonal changes if chronically demyelinated cervical spinal cord plaques
    • Lovas G., Szilagyi N., Majtenyi K., Palkovits M., and Komoly S. Axonal changes if chronically demyelinated cervical spinal cord plaques. Brain 123 (2000) 308-317
    • (2000) Brain , vol.123 , pp. 308-317
    • Lovas, G.1    Szilagyi, N.2    Majtenyi, K.3    Palkovits, M.4    Komoly, S.5
  • 87
    • 0345633543 scopus 로고    scopus 로고
    • A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases
    • Lucchinetti C., Bruck W., Parisi J., Scheithauer B., Rodriguez M., and Lassmann H. A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain 122 (1999) 2279-2295
    • (1999) Brain , vol.122 , pp. 2279-2295
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 88
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • Lucchinetti C., Bruck W., Parisi J., Scheithauer B., Rodriguez M., and Lassmann H. Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination. Ann. Neurol. 47 (2000) 707-717
    • (2000) Ann. Neurol. , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 89
    • 0018950016 scopus 로고
    • Chronic demyelination inhibits remyelination in the central nervous system
    • Ludwin S.K. Chronic demyelination inhibits remyelination in the central nervous system. Lab. Invest. 43 (1980) 382-387
    • (1980) Lab. Invest. , vol.43 , pp. 382-387
    • Ludwin, S.K.1
  • 90
    • 3142751087 scopus 로고    scopus 로고
    • Generation of transgenic mice expressing insulin-like growth factor-1 under the control of the myelin basic protein promoter: Increased myelination and potential for studies on the effects of increased IGF-1 on experimentally and genetically induced demyelination
    • Luzi P., Zaka M., Rao H.Z., Curtis M., Rafi M.A., and Wenger D.A. Generation of transgenic mice expressing insulin-like growth factor-1 under the control of the myelin basic protein promoter: Increased myelination and potential for studies on the effects of increased IGF-1 on experimentally and genetically induced demyelination. Neurochem. Res. 29 (2004) 881-889
    • (2004) Neurochem. Res. , vol.29 , pp. 881-889
    • Luzi, P.1    Zaka, M.2    Rao, H.Z.3    Curtis, M.4    Rafi, M.A.5    Wenger, D.A.6
  • 91
    • 0000197889 scopus 로고
    • Die sogenannte 'akute multiple Sklerose' (Encephalomyelitis periaxialis scleroticans)
    • Marburg O. Die sogenannte 'akute multiple Sklerose' (Encephalomyelitis periaxialis scleroticans). J. Neurol. Psychiatry 27 (1906) 213-312
    • (1906) J. Neurol. Psychiatry , vol.27 , pp. 213-312
    • Marburg, O.1
  • 92
    • 0034466119 scopus 로고    scopus 로고
    • Neuregulin in neuron/glial interactions in the central nervous system. GGF2 diminishes autoimmune demyelination, promotes oligodendrocyte progenitor expansion, and enhances remyelination
    • Marchionni M.A., Cannella B., Hoban C., Gao Y.L., Garcia-Arenas R., Lawson D., Happel E., Noel F., Tofilon P., Gwynne D., and Raine C.S. Neuregulin in neuron/glial interactions in the central nervous system. GGF2 diminishes autoimmune demyelination, promotes oligodendrocyte progenitor expansion, and enhances remyelination. Adv. Exp. Med. Biol. 468 (1999) 283-295
    • (1999) Adv. Exp. Med. Biol. , vol.468 , pp. 283-295
    • Marchionni, M.A.1    Cannella, B.2    Hoban, C.3    Gao, Y.L.4    Garcia-Arenas, R.5    Lawson, D.6    Happel, E.7    Noel, F.8    Tofilon, P.9    Gwynne, D.10    Raine, C.S.11
  • 94
    • 0027152081 scopus 로고
    • A role for TGF-beta in oligodendrocyte differentiation
    • McKinnon R.D., Piras G., Ida J.A., and Dubois-Dalcq M. A role for TGF-beta in oligodendrocyte differentiation. J. Cell Biol. 121 (1993) 1397-1407
    • (1993) J. Cell Biol. , vol.121 , pp. 1397-1407
    • McKinnon, R.D.1    Piras, G.2    Ida, J.A.3    Dubois-Dalcq, M.4
  • 96
    • 0034667585 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 (FGF2) and FGF receptor expression in an experimental demyelinating disease with extensive remyelination
    • Messersmith D.J., Murtie J.C., Le T.Q., Frost E.E., and Armstrong R.C. Fibroblast growth factor 2 (FGF2) and FGF receptor expression in an experimental demyelinating disease with extensive remyelination. J. Neurosci. Res. 62 (2000) 241-256
    • (2000) J. Neurosci. Res. , vol.62 , pp. 241-256
    • Messersmith, D.J.1    Murtie, J.C.2    Le, T.Q.3    Frost, E.E.4    Armstrong, R.C.5
  • 98
    • 0032713353 scopus 로고    scopus 로고
    • Contact with central nervous system myelin inhibits oligodendrocyte progenitor maturation
    • Miller R.H. Contact with central nervous system myelin inhibits oligodendrocyte progenitor maturation. Dev. Biol. 216 (1999) 359-368
    • (1999) Dev. Biol. , vol.216 , pp. 359-368
    • Miller, R.H.1
  • 99
    • 17444367733 scopus 로고    scopus 로고
    • PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination
    • Murtie J.C., Zhou Y.X., Le T.Q., Vana A.C., and Armstrong R.C. PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination. Neurobiol. Dis. 19 (2005) 171-182
    • (2005) Neurobiol. Dis. , vol.19 , pp. 171-182
    • Murtie, J.C.1    Zhou, Y.X.2    Le, T.Q.3    Vana, A.C.4    Armstrong, R.C.5
  • 100
    • 0023147156 scopus 로고
    • Secretory products of macrophages
    • Review
    • Nathan C.F. Secretory products of macrophages. J. Clin. Invest. 79 (1987) 319-326 Review
    • (1987) J. Clin. Invest. , vol.79 , pp. 319-326
    • Nathan, C.F.1
  • 101
    • 0010925052 scopus 로고    scopus 로고
    • Myelin specific genes and their mutations in the mouse
    • Jessen K.R., and Richardson W.D. (Eds), Oxford University Press, Oxford, UK
    • Nave K.A. Myelin specific genes and their mutations in the mouse. In: Jessen K.R., and Richardson W.D. (Eds). "Glial Cell Development" (2001), Oxford University Press, Oxford, UK 177-208
    • (2001) "Glial Cell Development" , pp. 177-208
    • Nave, K.A.1
  • 102
    • 0033844764 scopus 로고    scopus 로고
    • Patients with active relapsing-remitting multiple sclerosis synthesize antibodies recognizing oligodendrocyte progenitor cell surface protein: Implications for remyelination
    • Niehaus A., Shi J., Grzenkowski M., Diers-Fenger M., Archelos J., Hartung H.P., Toyka K., Bruck W., and Trotter J. Patients with active relapsing-remitting multiple sclerosis synthesize antibodies recognizing oligodendrocyte progenitor cell surface protein: Implications for remyelination. Ann. Neurol. 48 (2000) 362-371
    • (2000) Ann. Neurol. , vol.48 , pp. 362-371
    • Niehaus, A.1    Shi, J.2    Grzenkowski, M.3    Diers-Fenger, M.4    Archelos, J.5    Hartung, H.P.6    Toyka, K.7    Bruck, W.8    Trotter, J.9
  • 103
    • 13544264789 scopus 로고    scopus 로고
    • Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation
    • Nistor G.I., Totoiu M.O., Haque N., Carpenter M.K., and Keirstead H.S. Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation. Glia 49 (2005) 385-396
    • (2005) Glia , vol.49 , pp. 385-396
    • Nistor, G.I.1    Totoiu, M.O.2    Haque, N.3    Carpenter, M.K.4    Keirstead, H.S.5
  • 104
    • 0037395114 scopus 로고    scopus 로고
    • Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain
    • Nunes M.C., Roy N.S., Keyoung H.M., Goodman R.R., McKhann G., Jiang L., Kang J., Nedergaard M., and Goldman S.A. Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain. Nat. Med. 9 (2003) 439-447
    • (2003) Nat. Med. , vol.9 , pp. 439-447
    • Nunes, M.C.1    Roy, N.S.2    Keyoung, H.M.3    Goodman, R.R.4    McKhann, G.5    Jiang, L.6    Kang, J.7    Nedergaard, M.8    Goldman, S.A.9
  • 105
    • 0030936281 scopus 로고    scopus 로고
    • Oligodendrocyte precursors survive poorly and do not migrate following transplantation into the normal adult central nervous system
    • O'Leary M.T., and Blakemore W.F. Oligodendrocyte precursors survive poorly and do not migrate following transplantation into the normal adult central nervous system. J. Neurosci. Res. 48 (1997) 159-167
    • (1997) J. Neurosci. Res. , vol.48 , pp. 159-167
    • O'Leary, M.T.1    Blakemore, W.F.2
  • 106
    • 0036154986 scopus 로고    scopus 로고
    • Increasing local levels of IGF-I mRNA expression using adenoviral vectors does not alter oligodendrocyte remyelination in the CNS of aged rats
    • O'Leary M.T., Hinks G.L., Charlton H.M., and Franklin R.J. Increasing local levels of IGF-I mRNA expression using adenoviral vectors does not alter oligodendrocyte remyelination in the CNS of aged rats. Mol. Cell. Neurosci. 19 (2002) 32-42
    • (2002) Mol. Cell. Neurosci. , vol.19 , pp. 32-42
    • O'Leary, M.T.1    Hinks, G.L.2    Charlton, H.M.3    Franklin, R.J.4
  • 108
    • 30444442133 scopus 로고    scopus 로고
    • Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat
    • Papadopoulos D., Pham-Dinh D., and Reynolds R. Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat. Exp. Neurol. 197 (2006) 373-385
    • (2006) Exp. Neurol. , vol.197 , pp. 373-385
    • Papadopoulos, D.1    Pham-Dinh, D.2    Reynolds, R.3
  • 109
    • 0038692009 scopus 로고    scopus 로고
    • Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system
    • Penderis J., Shields S.A., and Franklin R.J.M. Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system. Brain 126 (2003) 1382-1391
    • (2003) Brain , vol.126 , pp. 1382-1391
    • Penderis, J.1    Shields, S.A.2    Franklin, R.J.M.3
  • 110
    • 1642422392 scopus 로고    scopus 로고
    • Increasing local levels of neuregulin (glial growth factor-2) by direct infusion into areas of demyelination does not alter remyelination in the rat CNS
    • Penderis J., Woodruff R.H., Lakatos A., Li W.W., Dunning M.D., Zhao C., Marchionni M., and Franklin R.J. Increasing local levels of neuregulin (glial growth factor-2) by direct infusion into areas of demyelination does not alter remyelination in the rat CNS. Eur. J. Neurosci. 18 (2003) 2253-2264
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 2253-2264
    • Penderis, J.1    Woodruff, R.H.2    Lakatos, A.3    Li, W.W.4    Dunning, M.D.5    Zhao, C.6    Marchionni, M.7    Franklin, R.J.8
  • 111
    • 0013828898 scopus 로고
    • Electron microscopic features of multiple sclerosis lesions
    • Perier O., and Gregoire A. Electron microscopic features of multiple sclerosis lesions. Brain 88 (1965) 937-952
    • (1965) Brain , vol.88 , pp. 937-952
    • Perier, O.1    Gregoire, A.2
  • 112
    • 20444423819 scopus 로고    scopus 로고
    • The therapeutic use of stem cells for myelin repair in autoimmune demyelinating disorders
    • Review
    • Pluchino S., and Martino G. The therapeutic use of stem cells for myelin repair in autoimmune demyelinating disorders. J. Neurol. Sci. 233 (2005) 117-119 Review
    • (2005) J. Neurol. Sci. , vol.233 , pp. 117-119
    • Pluchino, S.1    Martino, G.2
  • 113
    • 17844394405 scopus 로고    scopus 로고
    • Neural stem cells and their use as therapeutic tool in neurological disorders
    • Pluchino S., Zanotti L., Deleidi M., and Martino G. Neural stem cells and their use as therapeutic tool in neurological disorders. Brain Res. Brain Res. Rev. 48 (2005) 211-219
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 211-219
    • Pluchino, S.1    Zanotti, L.2    Deleidi, M.3    Martino, G.4
  • 114
    • 29644445235 scopus 로고    scopus 로고
    • NG2-expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult central nervous system
    • Review
    • Polito A., and Reynolds R. NG2-expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult central nervous system. J. Anat. 207 (2005) 707-716 Review
    • (2005) J. Anat. , vol.207 , pp. 707-716
    • Polito, A.1    Reynolds, R.2
  • 115
    • 0018410045 scopus 로고
    • Remyelination in multiple sclerosis
    • Prineas J.W., and Connell F. Remyelination in multiple sclerosis. Ann. Neurol. 5 (1979) 22-31
    • (1979) Ann. Neurol. , vol.5 , pp. 22-31
    • Prineas, J.W.1    Connell, F.2
  • 116
    • 0021647150 scopus 로고
    • Continual breakdown and regeneration of myelin in progressive multiple sclerosis plaques
    • Prineas J.W., Kwon E.E., Cho E.S., and Sharer L.R. Continual breakdown and regeneration of myelin in progressive multiple sclerosis plaques. Ann. N. Y. Acad. Sci. 436 (1984) 11-32
    • (1984) Ann. N. Y. Acad. Sci. , vol.436 , pp. 11-32
    • Prineas, J.W.1    Kwon, E.E.2    Cho, E.S.3    Sharer, L.R.4
  • 118
    • 0027173943 scopus 로고
    • Multiple sclerosis: Remyelination in acute lesions
    • Raine C.S., and Wu E. Multiple sclerosis: Remyelination in acute lesions. J. Neuropathol. Exp. Neurol. 52 (1993) 199-204
    • (1993) J. Neuropathol. Exp. Neurol. , vol.52 , pp. 199-204
    • Raine, C.S.1    Wu, E.2
  • 119
    • 0032533690 scopus 로고    scopus 로고
    • In vivo proliferation of oligodendrocyte progenitors expressing PDGFalphaR during early remyelination
    • Redwine J.M., and Armstrong R.C. In vivo proliferation of oligodendrocyte progenitors expressing PDGFalphaR during early remyelination. J. Neurobiol. 37 (1998) 413-428
    • (1998) J. Neurobiol. , vol.37 , pp. 413-428
    • Redwine, J.M.1    Armstrong, R.C.2
  • 120
    • 0037379348 scopus 로고    scopus 로고
    • A function of myelin is to protect axons from subsequent injury: Implications for deficits in multiple sclerosis
    • Rodriguez M. A function of myelin is to protect axons from subsequent injury: Implications for deficits in multiple sclerosis. Brain 126 (2003) 751-752
    • (2003) Brain , vol.126 , pp. 751-752
    • Rodriguez, M.1
  • 121
    • 0024445147 scopus 로고
    • Type 1 astrocytes inhibit myelination by adult rat oligodendrocytes in vitro
    • Rosen C.L., Bunge R.P., Ard M.D., and Wood P.M. Type 1 astrocytes inhibit myelination by adult rat oligodendrocytes in vitro. J. Neurosci. 9 (1989) 3371-3379
    • (1989) J. Neurosci. , vol.9 , pp. 3371-3379
    • Rosen, C.L.1    Bunge, R.P.2    Ard, M.D.3    Wood, P.M.4
  • 122
    • 32544437653 scopus 로고    scopus 로고
    • Molecular reconstruction of nodes of Ranvier after remyelination by transplanted olfactory ensheathing cells in the demyelinated spinal cord
    • Sasaki M., Black J.A., Lankford K.L., Tokuno H.A., Waxman S.G., and Kocsis J.D. Molecular reconstruction of nodes of Ranvier after remyelination by transplanted olfactory ensheathing cells in the demyelinated spinal cord. J. Neurosci. 26 (2006) 1803-1812
    • (2006) J. Neurosci. , vol.26 , pp. 1803-1812
    • Sasaki, M.1    Black, J.A.2    Lankford, K.L.3    Tokuno, H.A.4    Waxman, S.G.5    Kocsis, J.D.6
  • 123
    • 0344422922 scopus 로고
    • Zur Frage der akuten multiplen Sklerose und der encephalomyelitis disseminata im Kindesalter
    • Schlesinger H. Zur Frage der akuten multiplen Sklerose und der encephalomyelitis disseminata im Kindesalter. Arb. Neurol. Inst. (Wien.) 17 (1909) 410-432
    • (1909) Arb. Neurol. Inst. (Wien.) , vol.17 , pp. 410-432
    • Schlesinger, H.1
  • 124
    • 0031797815 scopus 로고    scopus 로고
    • Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis
    • Scolding N., Franklin R., Stevens S., Heldin C.H., Compston A., and Newcombe J. Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis. Brain 121 (1998) 2221-2228
    • (1998) Brain , vol.121 , pp. 2221-2228
    • Scolding, N.1    Franklin, R.2    Stevens, S.3    Heldin, C.H.4    Compston, A.5    Newcombe, J.6
  • 126
    • 25144469422 scopus 로고    scopus 로고
    • Mechanisms of axon ensheathment and myelin growth
    • Sherman D.L., and Brophy P.J. Mechanisms of axon ensheathment and myelin growth. Nat. Rev. Neurosci. 6 (2005) 683-690
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 683-690
    • Sherman, D.L.1    Brophy, P.J.2
  • 127
    • 0032526701 scopus 로고    scopus 로고
    • Purification and characterization of adult oligodendrocyte precursor cells from the rat optic nerve
    • Shi J., Marinovich A., and Barres B.A. Purification and characterization of adult oligodendrocyte precursor cells from the rat optic nerve. J. Neurosci. 18 (1998) 4627-4636
    • (1998) J. Neurosci. , vol.18 , pp. 4627-4636
    • Shi, J.1    Marinovich, A.2    Barres, B.A.3
  • 128
    • 0036549138 scopus 로고    scopus 로고
    • The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation
    • Sim F.J., Zhao C., Penderis J., and Franklin R.J.M. The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J. Neurosci. 22 (2002) 2451-2459
    • (2002) J. Neurosci. , vol.22 , pp. 2451-2459
    • Sim, F.J.1    Zhao, C.2    Penderis, J.3    Franklin, R.J.M.4
  • 129
    • 0018774226 scopus 로고
    • Central remyelination restores secure conduction
    • Smith E.J., Blakemore W.F., and McDonald W.I. Central remyelination restores secure conduction. Nature 280 (1979) 395-396
    • (1979) Nature , vol.280 , pp. 395-396
    • Smith, E.J.1    Blakemore, W.F.2    McDonald, W.I.3
  • 130
    • 0019787678 scopus 로고
    • The restoration of conduction by central remyelination
    • Smith K.J., Blakemore W.F., and McDonald W.I. The restoration of conduction by central remyelination. Brain 104 (1981) 383-404
    • (1981) Brain , vol.104 , pp. 383-404
    • Smith, K.J.1    Blakemore, W.F.2    McDonald, W.I.3
  • 131
    • 0041625961 scopus 로고    scopus 로고
    • Quantifying the early stages of remyelination following cuprizone-induced demyelination
    • Stidworthy M.F., Genoud S., Suter U., Mantei N., and Franklin R.J.M. Quantifying the early stages of remyelination following cuprizone-induced demyelination. Brain Pathol. 13 (2003) 329-339
    • (2003) Brain Pathol. , vol.13 , pp. 329-339
    • Stidworthy, M.F.1    Genoud, S.2    Suter, U.3    Mantei, N.4    Franklin, R.J.M.5
  • 134
    • 0030661759 scopus 로고    scopus 로고
    • Inflammation promotes survival and migration of the CG4 oligodendrocyte progenitors transplanted in the spinal cord of both inflammatory and demyelinated EAE rats
    • Tourbah A., Linnington C., Bachelin C., Avellana-Adalid V., Wekerle H., and Baron-Van Evercooren A. Inflammation promotes survival and migration of the CG4 oligodendrocyte progenitors transplanted in the spinal cord of both inflammatory and demyelinated EAE rats. J. Neurosci. Res. 50 (1997) 853-861
    • (1997) J. Neurosci. Res. , vol.50 , pp. 853-861
    • Tourbah, A.1    Linnington, C.2    Bachelin, C.3    Avellana-Adalid, V.4    Wekerle, H.5    Baron-Van Evercooren, A.6
  • 136
    • 33644861541 scopus 로고    scopus 로고
    • Promotion of remyelination by immunoglobulins: Implications for the treatment of multiple sclerosis
    • Trebst C., and Stangel M. Promotion of remyelination by immunoglobulins: Implications for the treatment of multiple sclerosis. Curr. Pharm. Des. 12 (2006) 241-249
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 241-249
    • Trebst, C.1    Stangel, M.2
  • 137
    • 0022633485 scopus 로고
    • The effect of dexamethasone on L-alpha-lysophosphatidyl choline (lysolecithin)-induced demyelination of the rat spinal cord
    • Triarhou L.C., and Herndon R.M. The effect of dexamethasone on L-alpha-lysophosphatidyl choline (lysolecithin)-induced demyelination of the rat spinal cord. Arch. Neurol. 43 (1986) 121-125
    • (1986) Arch. Neurol. , vol.43 , pp. 121-125
    • Triarhou, L.C.1    Herndon, R.M.2
  • 138
    • 0035679685 scopus 로고    scopus 로고
    • Neuregulin: An oligodendrocyte growth factor absent in active multiple sclerosis lesions
    • Viehover A., Miller R.H., Park S.K., Fischbach G., and Vartanian T. Neuregulin: An oligodendrocyte growth factor absent in active multiple sclerosis lesions. Dev. Neurosci. 23 (2001) 377-386
    • (2001) Dev. Neurosci. , vol.23 , pp. 377-386
    • Viehover, A.1    Miller, R.H.2    Park, S.K.3    Fischbach, G.4    Vartanian, T.5
  • 140
    • 33646731764 scopus 로고    scopus 로고
    • Ions, energy and axonal injury: Towards a molecular neurology of multiple sclerosis
    • Waxman S.G. Ions, energy and axonal injury: Towards a molecular neurology of multiple sclerosis. Trends Mol. Med. 12 (2006) 192-195
    • (2006) Trends Mol. Med. , vol.12 , pp. 192-195
    • Waxman, S.G.1
  • 141
    • 0034794081 scopus 로고    scopus 로고
    • A role for oligodendrocyte-derived IGF-1 in trophic support of cortical neurons
    • Wilkins A., Chandran S., and Compston A. A role for oligodendrocyte-derived IGF-1 in trophic support of cortical neurons. Glia 36 (2001) 48-57
    • (2001) Glia , vol.36 , pp. 48-57
    • Wilkins, A.1    Chandran, S.2    Compston, A.3
  • 142
    • 0031962240 scopus 로고    scopus 로고
    • Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
    • Wolswijk G. Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J. Neurosci. 18 (1998) 601-609
    • (1998) J. Neurosci. , vol.18 , pp. 601-609
    • Wolswijk, G.1
  • 143
    • 0036158610 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord
    • Wolswijk G. Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord. Brain 125 (2002) 338-349
    • (2002) Brain , vol.125 , pp. 338-349
    • Wolswijk, G.1
  • 144
    • 0033082118 scopus 로고    scopus 로고
    • Demyelination and remyelination of the caudal cerebellar peduncle of adult rats following stereotaxic injections of lysolecithin, ethidium bromide, and complement/anti-galactocerebroside: A comparative study
    • Woodruff R.H., and Franklin R.J.M. Demyelination and remyelination of the caudal cerebellar peduncle of adult rats following stereotaxic injections of lysolecithin, ethidium bromide, and complement/anti-galactocerebroside: A comparative study. Glia 25 (1999) 216-228
    • (1999) Glia , vol.25 , pp. 216-228
    • Woodruff, R.H.1    Franklin, R.J.M.2
  • 145
    • 1542425338 scopus 로고    scopus 로고
    • Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination
    • Woodruff R.H., Fruttiger M., Richardson W.D., and Franklin R.J.M. Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination. Mol. Cell. Neurosci. 25 (2004) 252-262
    • (2004) Mol. Cell. Neurosci. , vol.25 , pp. 252-262
    • Woodruff, R.H.1    Fruttiger, M.2    Richardson, W.D.3    Franklin, R.J.M.4
  • 146
    • 0028865130 scopus 로고
    • In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: Studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice
    • Ye P., Carson J., and D'Ercole A.J. In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: Studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice. J. Neurosci. 15 (1995) 7344-7356
    • (1995) J. Neurosci. , vol.15 , pp. 7344-7356
    • Ye, P.1    Carson, J.2    D'Ercole, A.J.3


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