The presence of astrocytes in areas of demyelination influences remyelination following transplantation of oligodendrocyte progenitors

Experimental Neurology

Volumn 184, Issue 2, 2003, Pages 955-963

  Blakemore, William F ^a   Gilson, Jennifer M ^a   Crang, A John ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Astrocytes; Multiple sclerosis; OPC; Schwann cells; Transplantation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; CELL INTERACTION; CELL TRANSPLANTATION; DEMYELINATION; FEMALE; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; REMYELINIZATION; SCHWANN CELL; STEM CELL;

EID: 0842342523     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4886(03)00347-9     Document Type: Article

References (25)

1. Ader M., Meng J.H., Schachner M., Bartsch U. Formation of myelin after transplantation of neural precursor cells into the retina of young postnatal mice. Glia. 30:2000;301-310.
2. Albrecht P.J., Dahl J.P., Stoltzfus O.K., Levenson R., Levison S.W. Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival. Exp. Neurol. 173:2002;46-62.
3. Blakemore W.F., Crang A.J. Transplantation of glial cells into areas of demyelination in the adult rat spinal cord. Dunnett S., Bjorklund A. Neural Transplantation: A Practical Approach. 1992;105-122 Oxford Univ. Press, Oxford.
4. Blakemore W.F., Franklin R.J.M. Transplantation options for therapeutic CNS remyelination. Cell Transplant. 9:2000;289-294.
5. Blakemore W.F., Gilson J.M., Crang A.J. Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells. J. Neurosci. Res. 61:2000;288-294.
6. Blakemore W.F., Chari D.M., Gilson J.M., Crang A.J. Modelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS. Glia. 38:2002;155-168.
7. Franklin R.J.M. Why does remyelination fail in multiple sclerosis. Nat. Rev., Neurosci. 3:2002;1-12.
8. Franklin R.J.M., Crang A.J., Blakemore W.F. Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord. J. Neurocytol. 20:1991;420-430.
9. Franklin R.J.M., Crang A.J., Blakemore W.F. The role of astrocytes in the remyelination of glial-free areas of demyelination. Seil F.J. Neural Regeneration. 1993;125-133 Raven Press, New York.
10. Franklin R.J.M., Gilson J.M., Blakemore W.F. Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system. J. Neurosci. Res. 50:1997;337-344.
11. Franklin R.J.M., Zhao C., Sim F.J. Astrocyte and macrophage interactions in promoting oligodendrocyte remyelination of the CNS. Aldskogius H., Fraher J. Glial Interfaces in the Nervous System. 2002;95-104 IOS Press, Amsterdam.
12. Gilson J.M., Blakemore W.F. Schwann cell remyelination is not replaced by oligodendrocyte remyelination following ethidium bromide induced demyelination. NeuroReport. 13:2002;1205-1208.
13. Hinks G.L., Franklin R.J.M. Distinctive patterns of PDGF-A, FGF-2, IGF-1, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination. Mol. Cell. Neurosci. 14:1999;153-168.
14. Hinks G.L., Chari D.M., O'Leary M.T., Zhao C., Keirstead H.S., Blakemore W.F., Franklin R.J.M. Depletion of endogenous oligodendrocyte progenitors rather than increased availability of survival factors is a likely explanation for the enhanced survival of transplanted oligodendrocyte progenitors in X-irradiated compared to normal CNS. Neuropathol. Appl. Neurobiol. 27:2001;59-67.
15. Hunter S.F., Leavitt J.A., Rodriguez M. Direct observation of myelination in vivo in the mature human central nervous system - A model for the behaviour of oligodendrocyte progenitors and their progeny. Brain. 120:1997;2071-2082.
16. Kamiguchi H., Yoshida K., Wakamoto H., Inaba M., Sasaki H., Otani M., Toya S. Cytokine-induced selective increase of high-molecular-weight bFGF isoforms and their subcellular kinetics in cultured rat hippocampal astrocytes. Neurochem. Res. 21:1996;701-706.
17. Keirstead H.S., Ben-Hur T., Rogister B., O'Leary M.T., Dubois-Dalcq M., Blakemore W.F. PSA-NCAM positive CNS precursors generate both oligodendrocytes and Schwann cells to remyelinate the CNS following transplantation. J. Neurosci. 19:1999;7529-7536.
18. Laeng P., Molthagen M., Yu E.G.X., Bartsch U. Transplantation of oligodendrocyte progenitor cells into the rat retina: extensive myelination of retinal ganglion cell axons. Glia. 18:1996;200-210.
19. Mason J.L., Suzuki K., Chaplin D.D., Matsushima G.K. Interleukin-1β promotes repair of the CNS. J. Neurosci. 21:2001;7046-7052.
20. Mckinnon R.D., Piras G., Ida J.A. Jr., Dubois-Dalcq M. A role for TGF-β in oligodendrocyte differentiation. J. Cell Biol. 121:1993;1397-1407.
21. Morcos Y., Chan-Ling T.L. Identification of oligodendrocyte precursors in the myelinated streak of the adult rabbit retina in vivo. Glia. 21:1997;163-182.
22. Sawada M., Suzumura A., Marunouchi T. Cytokine network in the central nervous system and its roles in growth and differentiation of glial and neuronal cells. Int. J. Dev. Neurosci. 13:1995;253-264.
23. Schuster N., Bender H., Philippi A., Subramaniam S., Strelau J., Wang Z., Krieglstein K. TGF-beta induces cell death in the oligodendroglial cell line OLI-neu. Glia. 40:2002;95-108.
24. Seo J.H., Haam Y.G., Park S.W., Kim D.W., Jeon G.S., Lee C., Hwang D.H., Kim Y.S., Cho S.S. Oligodendroglia in the avian retina: immunocytochemical demonstration in the adult bird. J. Neurosci. Res. 65:2001;173-183.
25. Zhang S.C., Duncan I.D. Remyelination and restoration of axonal function by glial cell transplantation. Dunnett S., Bjorklund A. Functional Neural Transplantation II: Novel Cell Therapies for CNS Disorders. 2000;515-533 Elsevier, Amsterdam/New York/Oxford.