Generation of transgenic mice expressing insulin-like growth factor-1 under the control of the myelin basic protein promoter: Increased myelination and potential for studies on the effects of increased IGF-1 on experimentally and genetically induced demyelination

Neurochemical Research

Volumn 29, Issue 5, 2004, Pages 881-889

  Luzi, Paola ^a   Zaka, Mariam ^a   Han, Zhi Rao ^a   Curtis, Mark ^a   Rafi, Mohammad A ^a   Wenger, David A ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Apoptosis; Growth factors; Insulin like growth factor 1; Leukodystrophies; Myelination; Transgenic mouse

Indexed keywords

MYELIN BASIC PROTEIN; SOMATOMEDIN C; MESSENGER RNA;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BEHAVIOR; BLOOD LEVEL; BRAIN; CLINICAL FEATURE; CONTROLLED STUDY; DEMYELINATION; ELECTRON MICROSCOPY; GENE CONTROL; GENE OVEREXPRESSION; GENETIC DISORDER; HETEROZYGOTE; LEUKODYSTROPHY; MICROSCOPY; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REMYELINIZATION; TIME SERIES ANALYSIS; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; DEMYELINATING DISEASE; GENETICS; IMMUNOHISTOCHEMISTRY; NORTHERN BLOTTING; PHYSIOLOGY; WESTERN BLOTTING;

ANIMALIA; MUS MUSCULUS;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DEMYELINATING DISEASES; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELIN BASIC PROTEINS; PROMOTER REGIONS (GENETICS); RNA, MESSENGER;

EID: 3142751087     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000021233.79076.72     Document Type: Article

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