Increasing local levels of neuregulin (glial growth factor-2) by direct infusion into areas of demyelination does not alter remyelination in the rat CNS

European Journal of Neuroscience

Volumn 18, Issue 8, 2003, Pages 2253-2264

  Penderis, Jacques ^a,b   Woodruff, Rachel H ^a   Lakatos, Andras ^a   Li, Wen Wu ^a   Dunning, Mark D ^a   Zhao, Chao ^a   Marchionni, Mark ^c   Franklin, Robin J M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ANIMAL HEALTH TRUST   (United Kingdom)

^c CeNeS Pharmaceuticals plc   (United States)

Author keywords

Ethidium bromide; GGF 2; Multiple sclerosis; Oligodendrocyte; Schwann cell

Indexed keywords

GLIOTOXIN; NEU DIFFERENTIATION FACTOR; NEURITE PROMOTING FACTOR; NEURITE PROMOTING FACTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATION; FEMALE; IMMUNOMODULATION; INFUSION; INFUSION PUMP; INJECTION SITE; MOLECULAR MODEL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; REMYELINIZATION;

ANIMALS; BROMODEOXYURIDINE; CELL COUNT; CELL DIVISION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DEMYELINATING DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; ENZYME INHIBITORS; ETHIDIUM; FEMALE; IMMUNOHISTOCHEMISTRY; INDOLES; MYELIN SHEATH; NERVE TISSUE PROTEINS; NEUREGULIN-1; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SCHWANN CELLS; TIME FACTORS;

EID: 1642422392     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02969.x     Document Type: Article

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