-
1
-
-
0026523086
-
Does lineage determine the dopamine phenotype in the tadpole hypothalamus?: A quantitative analysis
-
Huang, S. & Moody, S.A. Does lineage determine the dopamine phenotype in the tadpole hypothalamus?: A quantitative analysis. J. Neurosci. 12, 1351-1362 (1992).
-
(1992)
J. Neurosci.
, vol.12
, pp. 1351-1362
-
-
Huang, S.1
Moody, S.A.2
-
2
-
-
0031917477
-
Regulation in the heart field of zebrafish
-
Serbedzija, G.N., Chen, J.N. & Fishman, M.C. Regulation in the heart field of zebrafish. Development 125, 1095-1101 (1998).
-
(1998)
Development
, vol.125
, pp. 1095-1101
-
-
Serbedzija, G.N.1
Chen, J.N.2
Fishman, M.C.3
-
3
-
-
0025852445
-
A B cell deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene
-
Kitamura, D., Roes, J., Kuhn, R. & Rajewsky, K. A B cell deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 350, 423-426 (1991).
-
(1991)
Nature
, vol.350
, pp. 423-426
-
-
Kitamura, D.1
Roes, J.2
Kuhn, R.3
Rajewsky, K.4
-
4
-
-
0023669148
-
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene
-
Palmiter, R.D. et al. Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell 50, 435-443 (1987).
-
(1987)
Cell
, vol.50
, pp. 435-443
-
-
Palmiter, R.D.1
-
5
-
-
0023631457
-
Genetic ablation: Targeted expression of a toxin gene causes microphthalmia in transgenic mice
-
Breitman, M.L. et al. Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice. Science 238, 1563-1565 (1987).
-
(1987)
Science
, vol.238
, pp. 1563-1565
-
-
Breitman, M.L.1
-
6
-
-
0001077645
-
Effect of lymphocyte depletion by thoracic duct fistula and administration of anti-lymphocytic serum on the survival of skin homografts in rats
-
Woodruff, M.F. & Anderson, N.A. Effect of lymphocyte depletion by thoracic duct fistula and administration of anti-lymphocytic serum on the survival of skin homografts in rats. Nature 200, 702 (1963).
-
(1963)
Nature
, vol.200
, pp. 702
-
-
Woodruff, M.F.1
Anderson, N.A.2
-
7
-
-
0027348964
-
The role of astrocytes in the remyelination of glia-free areas of demyelination
-
Franklin, R.J., Crang, A.J. & Blakemore, W.F. The role of astrocytes in the remyelination of glia-free areas of demyelination. Adv. Neurol. 59, 125-133 (1993).
-
(1993)
Adv. Neurol.
, vol.59
, pp. 125-133
-
-
Franklin, R.J.1
Crang, A.J.2
Blakemore, W.F.3
-
8
-
-
0039205029
-
Targeting of an inducible toxic phenotype in animal cells
-
Borrelli, E., Heyman, R., Hsi, M. & Evans, R.M. Targeting of an inducible toxic phenotype in animal cells. Proc. Natl. Acad. Sci. USA 85, 7572-7576 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 7572-7576
-
-
Borrelli, E.1
Heyman, R.2
Hsi, M.3
Evans, R.M.4
-
9
-
-
8044241577
-
Selective cell ablation in transgenic mice expression E. coli nitroreductase
-
Clark, A.J. et al. Selective cell ablation in transgenic mice expression E. coli nitroreductase. Gene Ther. 4, 101-110 (1997).
-
(1997)
Gene Ther.
, vol.4
, pp. 101-110
-
-
Clark, A.J.1
-
10
-
-
0035434215
-
Interrogation by toxin
-
Palmiter, R. Interrogation by toxin. Nat. Biotechnol. 19, 731-732 (2001).
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 731-732
-
-
Palmiter, R.1
-
11
-
-
0025886840
-
The herpes simplex virus type 1 thymidine kinase is expressed in the testes of transgenic mice under the control of a cryptic promoter
-
al-Shawi, R. et al. The herpes simplex virus type 1 thymidine kinase is expressed in the testes of transgenic mice under the control of a cryptic promoter. Mol. Cell. Biol. 11, 4207-4216 (1991).
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 4207-4216
-
-
al-Shawi, R.1
-
12
-
-
0026747170
-
Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
-
Naglich, J.G., Metherall, J.E., Russell, D.W. & Eidels, L. Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 69, 1051-1061 (1992).
-
(1992)
Cell
, vol.69
, pp. 1051-1061
-
-
Naglich, J.G.1
Metherall, J.E.2
Russell, D.W.3
Eidels, L.4
-
13
-
-
0017350046
-
Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtheriae: Differential cytotoxicity
-
Middlebrook, J.L. & Dorland, R.B. Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtheriae: differential cytotoxicity. Can. J. Microbiol. 23, 183-189 (1977).
-
(1977)
Can. J. Microbiol.
, vol.23
, pp. 183-189
-
-
Middlebrook, J.L.1
Dorland, R.B.2
-
14
-
-
0020041572
-
Diphtheria toxin and related proteins: Effect of route of injection on toxicity and the determination of cytotoxicity for various cultured cells
-
Pappenheimer, A.M., Jr., Harper, A.A., Moynihan, M. & Brockes, J.P. Diphtheria toxin and related proteins: effect of route of injection on toxicity and the determination of cytotoxicity for various cultured cells. J. Infect. Dis. 145, 94-102 (1982).
-
(1982)
J. Infect. Dis.
, vol.145
, pp. 94-102
-
-
Pappenheimer Jr., A.M.1
Harper, A.A.2
Moynihan, M.3
Brockes, J.P.4
-
15
-
-
0034899321
-
Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice
-
Saito, M. et al. Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice. Nat. Biotechnol. 19, 746-750 (2001).
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 746-750
-
-
Saito, M.1
-
16
-
-
18644375874
-
In vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cell-associated antigens
-
Jung, S. et al. In vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cell-associated antigens. Immunity 17, 211-220 (2002).
-
(2002)
Immunity
, vol.17
, pp. 211-220
-
-
Jung, S.1
-
17
-
-
0038046761
-
Transgenic mice expressing the diphtheria toxin receptor are sensitive to the toxin
-
Cha, J.H., Chang, M.Y., Richardson, J.A. & Eidels, L. Transgenic mice expressing the diphtheria toxin receptor are sensitive to the toxin. Mol. Microbiol. 49, 235-240 (2003).
-
(2003)
Mol. Microbiol.
, vol.49
, pp. 235-240
-
-
Cha, J.H.1
Chang, M.Y.2
Richardson, J.A.3
Eidels, L.4
-
18
-
-
0015217329
-
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule
-
Drazin, R., Kandel, J. & Collier, R.J. Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule. J. Biol. Chem. 246, 1504-1510 (1971).
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 1504-1510
-
-
Drazin, R.1
Kandel, J.2
Collier, R.J.3
-
19
-
-
0015217293
-
Observations on the structure of diphtheria toxin
-
Gill, D.M. & Dinius, L.L. Observations on the structure of diphtheria toxin. J. Biol. Chem. 246, 1485-1491 (1971).
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 1485-1491
-
-
Gill, D.M.1
Dinius, L.L.2
-
20
-
-
0015218131
-
Adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis by diphtheria toxin
-
Honjo, T., Nishizuka, Y., Kato, I. & Hayaishi, O. Adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis by diphtheria toxin. J. Biol. Chem. 246, 4251-4260 (1971).
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 4251-4260
-
-
Honjo, T.1
Nishizuka, Y.2
Kato, I.3
Hayaishi, O.4
-
21
-
-
0018167496
-
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
-
Yamaizumi, M., Mekada, E., Uchida, T. & Okada, Y. One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell 15, 245-250 (1978).
-
(1978)
Cell
, vol.15
, pp. 245-250
-
-
Yamaizumi, M.1
Mekada, E.2
Uchida, T.3
Okada, Y.4
-
22
-
-
0343035756
-
Advances in gene targeting methods
-
Kühn, R. & Schwenk, F. Advances in gene targeting methods. Curr. Opin. Immunol. 9, 183-188 (1997).
-
(1997)
Curr. Opin. Immunol.
, vol.9
, pp. 183-188
-
-
Kühn, R.1
Schwenk, F.2
-
23
-
-
0028059099
-
Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting
-
Gu, H., Marth, J.D., Orban, P.C., Mossmann, H. & Rajewsky, K. Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting. Science 265, 103-106 (1994).
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
24
-
-
0026638820
-
Targeted oncogene activation by site-specific recombination in transgenic mice
-
Lakso, M. et al. Targeted oncogene activation by site-specific recombination in transgenic mice. Proc. Natl. Acad. Sci. USA 89, 6232-6236 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6232-6236
-
-
Lakso, M.1
-
25
-
-
0030990991
-
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells
-
Zambrowicz, B.P. et al. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc. Natl. Acad. Sci. USA 94, 3789-3794 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3789-3794
-
-
Zambrowicz, B.P.1
-
26
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano, P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71 (1999).
-
(1999)
Nat. Genet.
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
27
-
-
0033608980
-
Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice
-
Mao, X., Fujiwara, Y. & Orkin, S.H. Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc. Natl. Acad. Sci. USA 96, 5037-5042 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5037-5042
-
-
Mao, X.1
Fujiwara, Y.2
Orkin, S.H.3
-
28
-
-
0024328536
-
Altering the genome by homologous recombination
-
Capecchi, M.R. Altering the genome by homologous recombination. Science 244, 1288-1292 (1989).
-
(1989)
Science
, vol.244
, pp. 1288-1292
-
-
Capecchi, M.R.1
-
29
-
-
0027264498
-
Targeted disruption of the MHC class II Aa gene in C57BL/6 mice
-
Kontgen, F., Suss, G., Stewart, C., Steinmetz, M. & Bluethmann, H. Targeted disruption of the MHC class II Aa gene in C57BL/6 mice. Int. Immunol. 5, 957-964 (1993).
-
(1993)
Int. Immunol.
, vol.5
, pp. 957-964
-
-
Kontgen, F.1
Suss, G.2
Stewart, C.3
Steinmetz, M.4
Bluethmann, H.5
-
30
-
-
0037007121
-
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes
-
Peitz, M., Pfannkuche, K., Rajewsky, K. & Edenhofer, F. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc. Natl. Acad. Sci. USA 99, 4489-4494 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4489-4494
-
-
Peitz, M.1
Pfannkuche, K.2
Rajewsky, K.3
Edenhofer, F.4
-
31
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee, P.P. et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 15, 763-774 (2001).
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
-
32
-
-
0028242609
-
A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development
-
Sawada, S., Scarborough, J.D., Killeen, N. & Littman, D.R. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 77, 917-929 (1994).
-
(1994)
Cell
, vol.77
, pp. 917-929
-
-
Sawada, S.1
Scarborough, J.D.2
Killeen, N.3
Littman, D.R.4
-
33
-
-
0027989808
-
Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
-
Koopman, G. et al. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84, 1415-1420 (1994).
-
(1994)
Blood
, vol.84
, pp. 1415-1420
-
-
Koopman, G.1
-
34
-
-
0030818183
-
B lymphocyte-specific, Cre-mediated mutagenesis in mice
-
Rickert, R.C., Roes, J. & Rajewsky, K. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 25, 1317-1318 (1997).
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1317-1318
-
-
Rickert, R.C.1
Roes, J.2
Rajewsky, K.3
-
35
-
-
0037119628
-
IκB kinase signaling is essential for maintenance of mature B cells
-
Pasparakis, M., Schmidt-Supprian, M. & Rajewsky, K. IκB kinase signaling is essential for maintenance of mature B cells. J. Exp. Med. 196, 743-752 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 743-752
-
-
Pasparakis, M.1
Schmidt-Supprian, M.2
Rajewsky, K.3
-
36
-
-
2342471420
-
The blood-brain barrier: An overview: Structure, regulation, and clinical implications
-
Ballabh, P., Braun, A. & Nedergaard, M. The blood-brain barrier: an overview: Structure, regulation, and clinical implications. Neurobiol. Dis. 16, 1-13 (2004).
-
(2004)
Neurobiol. Dis.
, vol.16
, pp. 1-13
-
-
Ballabh, P.1
Braun, A.2
Nedergaard, M.3
-
37
-
-
0025331660
-
Diphtheria toxin effects on brain-tumor xenografts. Implications for protein-based brain-tumor chemotherapy
-
Wrobel, C.J., Wright, D.C., Dedrick, R.L. & Youle, R.J. Diphtheria toxin effects on brain-tumor xenografts. Implications for protein-based brain-tumor chemotherapy. J. Neurosurg. 72, 946-950 (1990).
-
(1990)
J. Neurosurg.
, vol.72
, pp. 946-950
-
-
Wrobel, C.J.1
Wright, D.C.2
Dedrick, R.L.3
Youle, R.J.4
-
38
-
-
0027328575
-
Myelin/oligodendrocyte glycoprotein is a member of a subset of the immunoglobulin superfamily encoded within the major histocompatibility complex
-
Pham-Dinh, D. et al. Myelin/oligodendrocyte glycoprotein is a member of a subset of the immunoglobulin superfamily encoded within the major histocompatibility complex. Proc. Natl. Acad. Sci. USA 90, 7990-7994 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7990-7994
-
-
Pham-Dinh, D.1
-
39
-
-
0023870209
-
Development of macroglial cells in rat cerebellum. II. An in situ immunohistochemical study of oligodendroglial lineage from precursor to mature myelinating cell
-
Reynolds, R. & Wilkin, G.P. Development of macroglial cells in rat cerebellum. II. An in situ immunohistochemical study of oligodendroglial lineage from precursor to mature myelinating cell. Development 102, 409-425 (1988).
-
(1988)
Development
, vol.102
, pp. 409-425
-
-
Reynolds, R.1
Wilkin, G.P.2
-
40
-
-
0032781971
-
Myelination in the absence of galactolipids and proteolipid proteins
-
Coetzee, T., Suzuki, K., Nave, K.A. & Popko, B. Myelination in the absence of galactolipids and proteolipid proteins. Mol. Cell. Neurosci. 14, 41-51 (1999).
-
(1999)
Mol. Cell. Neurosci.
, vol.14
, pp. 41-51
-
-
Coetzee, T.1
Suzuki, K.2
Nave, K.A.3
Popko, B.4
-
41
-
-
0142074391
-
Oligodendrocyte ablation impairs cerebellum development
-
Mathis, C., Collin, L. & Borrelli, E. Oligodendrocyte ablation impairs cerebellum development. Development 130, 4709-4718 (2003).
-
(2003)
Development
, vol.130
, pp. 4709-4718
-
-
Mathis, C.1
Collin, L.2
Borrelli, E.3
-
42
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
-
Schwenk, F., Baron, U. & Rajewsky, K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23, 5080-5081 (1995).
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Rajewsky, K.3
-
43
-
-
0023046991
-
Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance
-
Cobbold, S.P., Martin, G., Qin, S. & Waldmann, H. Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance. Nature 323, 164-166 (1986).
-
(1986)
Nature
, vol.323
, pp. 164-166
-
-
Cobbold, S.P.1
Martin, G.2
Qin, S.3
Waldmann, H.4
-
44
-
-
0029162602
-
+ T cell regulation during the induction phase of the response
-
+ T cell regulation during the induction phase of the response. Eur. J. Immunol. 25, 2643-2649 (1995).
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 2643-2649
-
-
Bushell, A.1
Morris, P.J.2
Wood, K.J.3
-
45
-
-
0027456571
-
Structural motifs involved in human IgG antibody effector functions
-
Greenwood, J., Clark, M. & Waldmann, H. Structural motifs involved in human IgG antibody effector functions. Eur. J. Immunol. 23, 1098-1104 (1993).
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 1098-1104
-
-
Greenwood, J.1
Clark, M.2
Waldmann, H.3
-
46
-
-
0030926207
-
Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-γ-secreting TH1 cells in humans
-
Rep, M.H. et al. Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-γ-secreting TH1 cells in humans. J. Clin. Invest. 99, 2225-2231 (1997).
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2225-2231
-
-
Rep, M.H.1
-
47
-
-
0035029433
-
A highly efficient ligand-regulated Cre recombinase mouse line shows that loxP recombination is position dependent
-
Vooijs, M., Jonkers, J. & Berns, A. A highly efficient ligand-regulated Cre recombinase mouse line shows that loxP recombination is position dependent. EMBO Rep. 2, 292-297 (2001).
-
(2001)
EMBO Rep.
, vol.2
, pp. 292-297
-
-
Vooijs, M.1
Jonkers, J.2
Berns, A.3
-
48
-
-
0003965483
-
Laboratory protocols for conditional gene targeting
-
(Oxford University Press, Oxford,)
-
Torres, R.M. & Kühn, R. Laboratory protocols for conditional gene targeting. (Oxford University Press, Oxford, 1997).
-
(1997)
-
-
Torres, R.M.1
Kühn, R.2
-
49
-
-
0023217559
-
+ B cells upon transfer of peritoneal cells into allotype-congenic newborn mice
-
+ B cells upon transfer of peritoneal cells into allotype-congenic newborn mice. Eur. J. Immunol. 17, 521-528 (1987).
-
(1987)
Eur. J. Immunol.
, vol.17
, pp. 521-528
-
-
Förster, I.1
Rajewsky, K.2
|