Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation

Brain

Volumn 125, Issue 3, 2002, Pages 551-561

  Garbern, James Y ^a   Yool, Donald A ^f   Moore, Gregory J ^a   Wilds, Ian B ^a   Faulk, Michael W ^a   Klugmann, Matthias ^e   Nave, Klaus Amin ^e   Sistermans, Erik A ^c   Van Der Knaap, Marjo S ^d   Bird, Thomas D ^b   Shy, Michael E ^a   Kamholz, John A ^a   Griffiths, Ian R ^f  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Axonal, proteolipid protein 1; DM20, N acetyl aspartate; Magnetic resonance spectroscopy; Pelizaeus Merzbacher disease

Indexed keywords

MYELIN PROTEIN; N ACETYLASPARTIC ACID; PROTEOLIPID PROTEIN; PROTEOLIPID PROTEIN 1; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ANIMAL TISSUE; ARTICLE; AUTOPSY; CELL INTERACTION; CENTRAL NERVOUS SYSTEM; DEMYELINATION; DISABILITY; DISEASE COURSE; GENE MUTATION; HUMAN; HUMAN TISSUE; INFLAMMATION; MOUSE; MULTIPLE SCLEROSIS; NERVE FIBER; NERVE FIBER DEGENERATION; NONHUMAN; OLIGODENDROGLIA; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0036189424     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awf043     Document Type: Article

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