Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination

Nature Neuroscience

Volumn 7, Issue 10, 2004, Pages 1088-1095

  Antony, Joseph M ^a   Van Marle, Guido ^a   Opii, Wycliffe ^b   Butterfield, D Allan ^b   Mallet, François ^c   Yong, Voon Wee ^a   Wallace, John L ^a   Deacon, Robert M ^d   Warren, Kenneth ^e   Power, Christopher ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITÉ DE LYON   (France)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FERULIC ACID; GLYCOPROTEIN; SYNCYTIN; UNCLASSIFIED DRUG; ANTIOXIDANT; COUMARIC ACID; HYBRID PROTEIN; MESSENGER RNA; PLACENTA PROTEIN; REACTIVE OXYGEN METABOLITE; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL DEATH; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOTOXICITY; DEMYELINATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; OLIGODENDROGLIA; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; UPREGULATION; ADULT; AGED; ANIMAL; CELL LINE; DISEASE MODEL; DRUG ANTAGONISM; ENCEPHALITIS; ENDOGENOUS RETROVIRUS; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MYELIN SHEATH; RAT; VIROLOGY;

ADULT; AGED; ANIMALS; ANTIOXIDANTS; ASTROCYTES; CELL DEATH; CELL LINE; COUMARIC ACIDS; DISEASE MODELS, ANIMAL; ENCEPHALITIS; ENDOGENOUS RETROVIRUSES; GENE PRODUCTS, ENV; HUMANS; MICE; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELIN SHEATH; OLIGODENDROGLIA; OXIDATION-REDUCTION; PREGNANCY PROTEINS; RATS; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER;

EID: 15544378974     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1319     Document Type: Article

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