Foxp3+ regulatory T cells in antiretroviral-naive HIV patients

AIDS

Volumn 20, Issue 12, 2006, Pages 1669-1671

  Montes, Martin ^a,b   Lewis, Dorothy E ^a   Sanchez, Cesar ^b   De Castilla, Diego Lopez ^b   Graviss, Edward A ^a   Seas, Carlos ^b   Gotuzzo, Eduardo ^b   White Jr , A Clinton ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b INSTITUTO DE MEDICINA TROPICAL ALEXANDER VON HUMBOLDT   (Peru)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; TRANSCRIPTION FACTOR FOXP3;

ARTICLE; AUTOIMMUNE DISEASE; CD4 LYMPHOCYTE COUNT; CD4+ CD25+ T LYMPHOCYTE; CELL COUNT; CELL FUNCTION; CORRELATION ANALYSIS; DISEASE PREDISPOSITION; FLOW CYTOMETRY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATORY DISEASE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE;

ADULT; AGED; CD4 LYMPHOCYTE COUNT; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; T-LYMPHOCYTES, REGULATORY;

EID: 33746675679     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000238415.98194.38     Document Type: Article

References (11)

1. Shelburne SA, Montes M, Hamill RJ. Immune reconstitution inflammatory syndrome: more answers, more questions. J Antimicrob Chemother 2006; 57:167-170.
2. Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol 2005; 6:331-337.
3. Belkaid Y, Rouse BT. Natural regulatory T cells in infectious disease. Nat Immunol 2005; 6:353-360.
4. Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001; 193:1285-1294.
5. Jiang H, Chess L. Regulation of immune responses by T cells. N Engl J Med 2006; 354:1166-1176.
6. Oswald-Richter K, Grill SM, Shariat N, Leelawong M, Sundrud MS, Haas DW, Unutmaz D. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Biol 2004; 2:955-966.
7. Kinter AL, Hennessey M, Bell A, Kern S, Lin Y, Daucher M, et al. CD25+CD4+ Regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4+ and CD8+ HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 2004; 200:331-343.
8. Eggena MP, Barugahare B, Jones N, Okello M, Mutalya S, Kityo C, et al. Depletion of regulatory T cells in HIV infection is associated with immune activation. J Immunol 2005; 174:4407-4414.
9. Apoil PA, Puissant B, Roubinet F, Abbal M, Massip P, Blancher A. FOXP3 mRNA levels are decreased in peripheral blood CD4+ lymphocytes from HIV-positive patients. J Acquir Immune Defic Syndr 2005; 39:381-385.
10. Weiss L, Donkova-Petrini V, Caccavelli L, Balbo M, Carbonneil C, Levy Y. Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 2004; 104:3249-3256.
11. Tsunemi S, Iwasaki T, Imado T, Higasa S, Kakishita E, Shirasaka T, Sano H. Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients. AIDS 2005; 19:879-886.