IL-1 receptor accessory protein is an essential component of the IL-1 receptor

Journal of Immunology

Volumn 161, Issue 10, 1998, Pages 5614-5620

  Cullinan, Emily B ^a   Kwee, Lia ^b   Nunes, Perla ^b   Shuster, David J ^b   Ju, Grace ^b   McIntyre, Kim W ^c   Chizzonite, Richard A ^d   Labow, Mark A ^b,e  

^a Chrysalis Corporation   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

^d BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA;

ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; GENE TARGETING; HOST RESISTANCE; INFLAMMATORY DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

EID: 0032533814     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Dinarello, C. A. 1996. Biologic basis for interleukin-1 in disease. Blood 87:2095.
2. Sims, J. E., C. J. March, D. Cosman, M. B. Widmer, H. R. MacDonald, C. J. McMahan, C. E. Grubin, J. M. Wignal, J. L. Jackson, S. M. Call, et al. 1988. cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 241:585.
3. McMahan, C. J., J. L. Slack, B. Mosley, D. Cosman, S. D. Lupton, L. L. Brunton, C. E. Grubin, J. M. Wignall, N. A. Jenkins, C. I. Brannan, et al. 1991. A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J. 10:2821.
4. Labow, M., D. Shuster, M. Zetterstrom, P. Nunes, R. Terry, E. B. Cullinan, T. Bartfai, L. L. Moldawer, R. A. Chizzonite, and K. W. McIntyre. 1997. Defective IL-1 signaling and reduced inflammatory response in IL-1 type I receptor deficient mice. J. Immunol. 159:2452.
5. Chizzonite, R. A., T. Truitt, P. L. Kilian, A. S. Stern, P. Nunes, K. P. Parker, K. L. Kaffka, A. O. Chua, D. K. Lugg, and U. Gubler. 1989. Two high-affinity interleukin 1 receptors represent separate gene products. Proc. Natl. Acad. Sci. USA 86:8029.
6. McIntyre, K. W., G. J. Stephan, K. D. Kolinsky, W. R. Benjamin, J. M. Plocinski, K. L. Kaffka, C. A. Campen, R. A. Chizzonite, and P. L. Kilian. 1991. Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody. J. Exp. Med. 173:931.
7. Colotta, F., F. Re, M. Muzio, B. Riccardo, N. Polentarutti, M. Sironi, J. G. Giri, S. K. Dower, J. E. Sims, and A. Mantovani. 1993. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 261:472.
8. Greenfeder, S. A., P. Nunes, L. Kwee, M. A. Labow, R. A. Chizzonite, and G. Ju. 1995. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270:13757.
9. Wesche, H., D. Neuman, K. Resch, and M. U. Martin. 1996. Co-expression of mRNA for type I and type II interleukin-1 receptors and the IL-1 receptor accessory protein correlates to IL-1 responsiveness. FEBS Lett. 391:104.
10. Korherr, C., R. Hofmeister, H. Wesche, and W. Falk. 1995. A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling. Eur. J. Immunol. 27:262.
11. Wesche, H. C. Korherr, M. Kracht, W. Falk, K. Resch, and M. U. Martin. 1997. The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases). J. Biol. Chem. 272:7727.
12. Huang, J., X. Gao, S. Li, and Z. Cao. 1997. Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein. Proc. Natl. Acad. Sci. USA 94:12829.
13. Curtis, B. M., B. Gallis, R. W. Overell, C. J. McMahan, P. DeRoos, R. Ireland, J. Eisenman, S. K. Dower, and J. E. Sims. 1989. T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1. Proc. Natl. Acad. Sci. USA 86:3045.
14. Mansour, S. L., K. R. Thomas, and M. R. Capecchi. 1988. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature 336:348.
15. Kwee, L., H. S. Baldwin, H. M. Shen, C. L. Stewart, C. Buck, C. A. Buck, M. A. Labow. 1995. Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice. Development 129:489.
16. Robertson, E. J. 1987. Teratocarcinomas and Embryonic Stem Cells: A Practical Approach. IRL Press, Oxford, England.
17. Mizel, S. B., P. L. Kilian, J. C. Lewis, K. A. Paganelli, and R. A. Chizzonite. 1987. The interleukin 1 receptor: dynamics of interleukin 1 binding and internalization in T cells and fibroblasts. J. Immunol. 138:2906.
18. Aarden, L. A., E. R. De Groot, O. L. Schaap, and P. M. Lansdorp. 1987. Production of hybridoma growth factor by human monocytes. Eur. J. Immunol. 17:1411.
19. Akira, S., and T. Kishimoto. 1992. IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol. Rev. 127:25.
20. Hu, E., E. Mueller, S. Oliviero, V. E. Papaioannou, R. Johnson, and B. M. Spiegelman. 1994. Targeted disruption of the c-fos gene demonstrates c-fos-dependent and independent pathways for gene expression stimulated by growth factors or oncogenes. EMBO J. 13:3094.
21. Isshiki, H., S. Akira, O. Tanabe, T. Nakajima, T. Shimamoto, T. Hirano, and T. Kishimoto. 1990. Constitutive and interleukin-1 (IL-1)-inducible-factors interact with the IL-1-responsive element in the IL-6 gene. Mol. Cell. Biol. 10:2757.
22. Libermann, T. A., and D. Baltimore. 1990. Activation of interleukin-6 gene expression through the NF-KB transcription factor. Mol. Cell. Biol. 10:2327.
23. Shimizu, H., K. Mitomo, T. Watanabe, S. Okamoto, and K.-I. Yamamoto. 1990. Involvement of a NF-κB-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines. Mol. Cell. Biol. 10:561.
24. Zhang, Y. H., J. X. Lin, and J. Vilcek. 1990. Interleukin-6 induction by tumor necrosis factor and interieukin-1 in human fibroblasts involves activation of a nuclear factor binding to a κB-like sequence. Mol. Cell. Biol. 10:3818.
25. Schindler, U., and V. R. Baichwal. 1994. Three NF-κB binding sites in the human E-selectin gene required for maximal tumor necrosis factor α-induced expression. Mol. Cell. Biol. 14:5820.
26. Probert, L., D. Plows, G. Kontogeorgos, and G. Kollias. 1995. The type I interieukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice. Eur. J. Immunol. 25:1794.
27. Joosten, L. A. B., M. M. A. Helsen. F. A. J. van de Loo, and W. B. van den Berg. 1996. Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFα. anti-IL-1α/β and IL-1Ra. Arthritis Rheum. 39:797.
28. Cao, Z., W. J. Henzel, and X. Gao. 1996. IRAK: a kinase associated with the interleukin-1 receptor. Science 271:1128.
29. Cao, Z., J. Xiong, M. Takeuchi, T. Kurama, and D. V. Goeddel. 1996. TRAF6 is a signal transducer for interleukin-1. Nature 383:443.
30. Tsukada, J., W. R. Waterman, Y. Koyama, A. C. Webb, and P. E. Auron. 1996. A novel STAT-like factor mediates lipopolysachharide, interleukin 1 (IL-1), and IL-6 signaling and recognizes a γ Interferon activation site-like element in the IL-1B gene. Mol. Cell. Biol. 16:2183.
31. Song, H. Y., M. Rothe, and D. V. Goeddel. 1996. The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NFκB activation. Proc. Natl. Acad. Sci. USA 93:6721.