-
1
-
-
27544513676
-
Gutless adenovirus: Last-generation adenovirus for gene therapy
-
Alba, R., Bosch, A. and Chillon, M. (2005) Gutless adenovirus: last-generation adenovirus for gene therapy. Gene. Ther., 12 Suppl 1: S18-S27.
-
(2005)
Gene. Ther.
, vol.12
, Issue.SUPPL. 1
-
-
Alba, R.1
Bosch, A.2
Chillon, M.3
-
2
-
-
0037422368
-
Circulation and biodistribution profiles of long-circulating PEG-liposomes of various sizes in rabbits
-
Awasthi, V. D., Garcia, D., Goins, B. A. and Phillips, W. T. (2003) Circulation and biodistribution profiles of long-circulating PEG-liposomes of various sizes in rabbits. Int. J. Pharm., 253: 121-132.
-
(2003)
Int. J. Pharm.
, vol.253
, pp. 121-132
-
-
Awasthi, V.D.1
Garcia, D.2
Goins, B.A.3
Phillips, W.T.4
-
3
-
-
0037566365
-
Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia
-
Belalcazar, L. M., Merched, A., Carr, B., Oka, K., Chen, K. H., Pastore, L., Beaudet, A. and Chan, L. (2003) Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia. Circulation, 107: 2726-2732.
-
(2003)
Circulation
, vol.107
, pp. 2726-2732
-
-
Belalcazar, L.M.1
Merched, A.2
Carr, B.3
Oka, K.4
Chen, K.H.5
Pastore, L.6
Beaudet, A.7
Chan, L.8
-
4
-
-
0033547789
-
Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models
-
Benoit, P., Emmanuel, F., Caillaud, J. M, Bassinet, L., Castro, G., Gallix, P., Fruchart, J. C., Branellec, D., Denefle, P. and Duverger, N. (1999) Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models. Circulation, 99: 105-110.
-
(1999)
Circulation
, vol.99
, pp. 105-110
-
-
Benoit, P.1
Emmanuel, F.2
Caillaud, J.M.3
Bassinet, L.4
Castro, G.5
Gallix, P.6
Fruchart, J.C.7
Branellec, D.8
Denefle, P.9
Duverger, N.10
-
5
-
-
23844466665
-
Gene therapy for lipoprotein disorders
-
Broedl, U. C. and Rader, D. J. (2005) Gene therapy for lipoprotein disorders. Expert Opin. Biol. Ther., 5: 1029-1038.
-
(2005)
Expert Opin. Biol. Ther.
, vol.5
, pp. 1029-1038
-
-
Broedl, U.C.1
Rader, D.J.2
-
6
-
-
0030460117
-
Adenoviral delivery of low-density lipoprotein receptors to hyperlipidemic -rabbits: Receptor expression modulates high-density lipoproteins
-
Brown, D. R., Brousseau, M. E., Shamburek, R. D., Talley, G. D., Meyn, S., Demosky, S. J. Jr., Santamarina-Fojo, S., Brewer, H. B, Jr. and Hoeg, J. M. (1996) Adenoviral delivery of low-density lipoprotein receptors to hyperlipidemic -rabbits: receptor expression modulates high-density lipoproteins. Metabolism, 45: 1447-1457.
-
(1996)
Metabolism
, vol.45
, pp. 1447-1457
-
-
Brown, D.R.1
Brousseau, M.E.2
Shamburek, R.D.3
Talley, G.D.4
Meyn, S.5
Demosky Jr., S.J.6
Santamarina-Fojo, S.7
Brewer Jr., H.B.8
Hoeg, J.M.9
-
7
-
-
0034264614
-
Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor
-
Chen, S. J., Rader, D. J., Tazelaar, J., Kawashiri, M., Gao, G. and Wilson, J. M. (2000) Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor. Mol. Ther., 2: 256-261.
-
(2000)
Mol. Ther.
, vol.2
, pp. 256-261
-
-
Chen, S.J.1
Rader, D.J.2
Tazelaar, J.3
Kawashiri, M.4
Gao, G.5
Wilson, J.M.6
-
8
-
-
0037396814
-
Apolipoprotein A-I(Milano): Current perspectives
-
Chiesa, G. and Sirtori, C. R. (2003) Apolipoprotein A-I(Milano): current perspectives. Curr. Opin. Lipidol., 14: 159-163.
-
(2003)
Curr. Opin. Lipidol.
, vol.14
, pp. 159-163
-
-
Chiesa, G.1
Sirtori, C.R.2
-
9
-
-
0026355641
-
Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits
-
Chowdhury, J. R., Grossman, M., Gupta, S., Chowdhury, N. R., Baker, J. R. Jr. and Wilson, J. M. (1991) Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits. Science, 254: 1802-1805.
-
(1991)
Science
, vol.254
, pp. 1802-1805
-
-
Chowdhury, J.R.1
Grossman, M.2
Gupta, S.3
Chowdhury, N.R.4
Baker Jr., J.R.5
Wilson, J.M.6
-
10
-
-
4644247930
-
Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage
-
Cichon, G., Willnow, T., Herwig, S., Uckert., W., Loser, P., Schmidt, H. H., Benhidjeb, T., Schlag, P. M., Schnieders, F., Niedzielska, D. and Heeren, J. (2004) Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage. J. Gene Med., 6: 166-175.
-
(2004)
J. Gene Med.
, vol.6
, pp. 166-175
-
-
Cichon, G.1
Willnow, T.2
Herwig, S.3
Uckert, W.4
Loser, P.5
Schmidt, H.H.6
Benhidjeb, T.7
Schlag, P.M.8
Schnieders, F.9
Niedzielska, D.10
Heeren, J.11
-
11
-
-
20544474017
-
An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis
-
Crooke, R. M., Graham, M. J., Lemonidis, K. M., Whipple, C. P., Koo, S. and Perera, R. J. (2005) An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis. J. Lipid. Res., 46: 872-884.
-
(2005)
J. Lipid. Res.
, vol.46
, pp. 872-884
-
-
Crooke, R.M.1
Graham, M.J.2
Lemonidis, K.M.3
Whipple, C.P.4
Koo, S.5
Perera, R.J.6
-
12
-
-
9244233812
-
Virosomes for antigen and DNA delivery
-
Daemen, T., de, M. A, Bungener, L., de, J. J., Huckriede, A. and Wilschut, J. (2005) Virosomes for antigen and DNA delivery. Adv. Drug. Deliv. Rev., 57: 451-463.
-
(2005)
Adv. Drug. Deliv. Rev.
, vol.57
, pp. 451-463
-
-
Daemen, T.deM.A.1
Bungener, L.deJ.J.2
Huckriede, A.3
Wilschut, J.4
-
13
-
-
0034297920
-
Effect of overexpression of human apo A-I in C57BL/6 and C57BL/6 apo E-deficient mice on 2 lipoprotein-associated enzymes, platelet-activating factor acetylhydrolase and paraoxonase. Comparison of adenovirus-mediated human apo A-I gene transfer and human apo A-I transgenesis
-
De Geest, B., Stengel, D., Landeloos, M., Lox, M., Le Gat, L., Collen, D., Holvoet, P. and Ninio, E. (2000a) Effect of overexpression of human apo A-I in C57BL/6 and C57BL/6 apo E-deficient mice on 2 lipoprotein-associated enzymes, platelet-activating factor acetylhydrolase and paraoxonase. Comparison of adenovirus-mediated human apo A-I gene transfer and human apo A-I transgenesis. Arterioscler. Thromb. Vasc. Biol., 20: E68-E75.
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
-
-
De Geest, B.1
Stengel, D.2
Landeloos, M.3
Lox, M.4
Le Gat, L.5
Collen, D.6
Holvoet, P.7
Ninio, E.8
-
14
-
-
0034746309
-
Sustained expression of human apo A-I following adenoviral gene transfer in mice
-
De Geest, B., Van Linthout, S. and Collen, D. (2001) Sustained expression of human apo A-I following adenoviral gene transfer in mice. Gene Ther., 8: 121-127.
-
(2001)
Gene Ther.
, vol.8
, pp. 121-127
-
-
De Geest, B.1
Van Linthout, S.2
Collen, D.3
-
15
-
-
0033982331
-
Sustained expression of human apolipoprotein A-I after adenoviral gene transfer in C57BL/6 mice: Role of apolipoprotein A-I promoter, apolipoprotein A-I introns. and human apolipoprotein E enhancer
-
De Geest, B., Van Linthout, S., Lox, M., Collen, D. and Holvoet, P. (2000b) Sustained expression of human apolipoprotein A-I after adenoviral gene transfer in C57BL/6 mice: role of apolipoprotein A-I promoter, apolipoprotein A-I introns. and human apolipoprotein E enhancer. Hum. Gene Ther., 11: 101-112.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 101-112
-
-
De Geest, B.1
Van Linthout, S.2
Lox, M.3
Collen, D.4
Holvoet, P.5
-
16
-
-
0031471857
-
Effects of adeno-virus-mediated human apo A-I gene transfer on neointima formation after endothelial denudation in apo E-deficient mice
-
De Geest, B., Zhao, Z., Collen, D. and Holvoet, P. (1997) Effects of adeno-virus-mediated human apo A-I gene transfer on neointima formation after endothelial denudation in apo E-deficient mice. Circulation, 96: 4349-4356.
-
(1997)
Circulation
, vol.96
, pp. 4349-4356
-
-
De Geest, B.1
Zhao, Z.2
Collen, D.3
Holvoet, P.4
-
17
-
-
0038446697
-
Humoral immune response in mice against a circulating antigen induced by adenoviral transfer is strictly dependent on expression in antigen-presenting cells
-
De Geest, B. R., Van Linthout, S. A. and Collen, D. (2003) Humoral immune response in mice against a circulating antigen induced by adenoviral transfer is strictly dependent on expression in antigen-presenting cells. Blood, 101: 2551-2556.
-
(2003)
Blood
, vol.101
, pp. 2551-2556
-
-
De Geest, B.R.1
Van Linthout, S.A.2
Collen, D.3
-
18
-
-
0026321996
-
Retroviral vector-mediated in vivo expression of low-density-lipoprotein receptors in the Watanabe heritable hyperlipidemic rabbit
-
Dichek, D. A., Bratthauer, G. L., Beg, Z. H. Anderson, K. D, Newman, K. D., Zwiebel, J. A., Hoeg, J. M. and Anderson, W. F. (1991) Retroviral vector-mediated in vivo expression of low-density-lipoprotein receptors in the Watanabe heritable hyperlipidemic rabbit. Somat. Cell Mol. Genet., 17: 287-301.
-
(1991)
Somat. Cell Mol. Genet.
, vol.17
, pp. 287-301
-
-
Dichek, D.A.1
Bratthauer, G.L.2
Beg, Z.H.3
Anderson, K.D.4
Newman, K.D.5
Zwiebel, J.A.6
Hoeg, J.M.7
Anderson, W.F.8
-
19
-
-
0034694055
-
Hammerhead ribozyme as a therapeutic agent for hyperlipidemia: Production of truncated apolipoprotein B and hypolipidemic effects in a dyslipidemia murine model
-
Enjoji, M., Wang, F., Nakamuta, M., Chan, L. and Teng, B. B. (2000) Hammerhead ribozyme as a therapeutic agent for hyperlipidemia: production of truncated apolipoprotein B and hypolipidemic effects in a dyslipidemia murine model. Hum. Gene Ther., 11: 2415-2430.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2415-2430
-
-
Enjoji, M.1
Wang, F.2
Nakamuta, M.3
Chan, L.4
Teng, B.B.5
-
20
-
-
17344366287
-
Correction of hypertriglyceridemia and impaired fat tolerance in lipoprotein lipase-deficient mice by adenovirus-mediated expression of human lipoprotein lipase
-
Excoffon, K. J., Liu, G., Miao, L., Wilson, J. E., McManus, B. M., Semenkovich, C. F., Coleman, T., Benoit, P., Duverger, N., Branellec, D., Denefle, P., Hayden, M. R. and Lewis, M. E. (1997) Correction of hypertriglyceridemia and impaired fat tolerance in lipoprotein lipase-deficient mice by adenovirus-mediated expression of human lipoprotein lipase. Arterioscler. Thromb. Vasc. Biol., 17: 2532-2539.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 2532-2539
-
-
Excoffon, K.J.1
Liu, G.2
Miao, L.3
Wilson, J.E.4
McManus, B.M.5
Semenkovich, C.F.6
Coleman, T.7
Benoit, P.8
Duverger, N.9
Branellec, D.10
Denefle, P.11
Hayden, M.R.12
Lewis, M.E.13
-
21
-
-
0031727714
-
Efficient coexpression and secretion of anti-atherogenic human apolipoprotein AI and lecithin-cholesterol acyltransferase by cultured muscle cells using adeno-associated virus plasmid vectors
-
Fan, L., Drew, J., Dunckley, M. G., Owen, J. S. and Dickson, G. (1998) Efficient coexpression and secretion of anti-atherogenic human apolipoprotein AI and lecithin-cholesterol acyltransferase by cultured muscle cells using adeno-associated virus plasmid vectors. Gene. Ther., 5: 1434-1440.
-
(1998)
Gene. Ther.
, vol.5
, pp. 1434-1440
-
-
Fan, L.1
Drew, J.2
Dunckley, M.G.3
Owen, J.S.4
Dickson, G.5
-
22
-
-
0032883857
-
Construction and characterization of polycistronic retrovirus vectors for sustained and high-level co-expression of apolipoprotein A-I and lecithin-cholesterol acyltransferase
-
Fan, L. Owen, J. S. and Dickson, G. (1999) Construction and characterization of polycistronic retrovirus vectors for sustained and high-level co-expression of apolipoprotein A-I and lecithin-cholesterol acyltransferase. Atherosclerosis, 147: 139-145.
-
(1999)
Atherosclerosis
, vol.147
, pp. 139-145
-
-
Fan, L.1
Owen, J.S.2
Dickson, G.3
-
23
-
-
9244234954
-
Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs
-
Felnerova, D., Viret, J. F., Gluck, R. and Moser, C. (2004) Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs. Curr. Opin. Biotechnol., 15: 518-529.
-
(2004)
Curr. Opin. Biotechnol.
, vol.15
, pp. 518-529
-
-
Felnerova, D.1
Viret, J.F.2
Gluck, R.3
Moser, C.4
-
24
-
-
0032055193
-
Effect of implantation of human apoAI gene on apoprotein composition and vasoactive properties of high-density lipoproteins in rats at different ages
-
Frolkis, V. V., Kulchitsky, O. K., Kordjum, V. A., Novikova, S. N., Sikalo, N. V., Potapenko, R. I., Irodov, D. M., Bogatskaya, L. N., Burchinskaya, M. K. and Mozzhukhina, T. G. (1998) Effect of implantation of human apoAI gene on apoprotein composition and vasoactive properties of high-density lipoproteins in rats at different ages. Mech. Ageing. Dev., 101: 213-219.
-
(1998)
Mech. Ageing. Dev.
, vol.101
, pp. 213-219
-
-
Frolkis, V.V.1
Kulchitsky, O.K.2
Kordjum, V.A.3
Novikova, S.N.4
Sikalo, N.V.5
Potapenko, R.I.6
Irodov, D.M.7
Bogatskaya, L.N.8
Burchinskaya, M.K.9
Mozzhukhina, T.G.10
-
25
-
-
0037015049
-
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
-
Gao, G. P., Alvira, M. R., Wang, L., Calcedo, R., Johnston, J. and Wilson, J. M. (2002) Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc. Natl. Acad. Sci. USA, 99: 11854-11859.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11854-11859
-
-
Gao, G.P.1
Alvira, M.R.2
Wang, L.3
Calcedo, R.4
Johnston, J.5
Wilson, J.M.6
-
26
-
-
0000600880
-
Familiar hypercholesterolemia
-
In: Eds. Scriver, C.R, Beauder, A.L, Sly, W.S. and Valle D. McGraw-Hill, New York
-
Goldstein, J. L., Hobbs, H. H. and Brown, M. S. (2001) Familiar hypercholesterolemia. In: The metabolic and molecular basis of inherited disease, Eds. Scriver, C.R, Beauder, A.L, Sly, W.S. and Valle D. McGraw-Hill, New York, pp. 2863-2913.
-
(2001)
The Metabolic and Molecular Basis of Inherited Disease
, pp. 2863-2913
-
-
Goldstein, J.L.1
Hobbs, H.H.2
Brown, M.S.3
-
27
-
-
0029794714
-
Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits
-
Greeve, J., Jona, V. K., Chowdhury, N. R., Horwitz, M. S. and Chowdhury, J. R. (1996) Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits. J. Lipid Res., 37: 2001-2017.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 2001-2017
-
-
Greeve, J.1
Jona, V.K.2
Chowdhury, N.R.3
Horwitz, M.S.4
Chowdhury, J.R.5
-
28
-
-
0028793489
-
A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia
-
Grossman, M., Rader, D. J., Muller, D. W., Kolansky, D. M., Kozarsky, K., Clark, B. J. III., Stein, E. A., Lupien, P. J., Brewer, H. B. Jr., Raper, S. E. (1995) A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia. Nat. Med., 1: 1148-1154.
-
(1995)
Nat. Med.
, vol.1
, pp. 1148-1154
-
-
Grossman, M.1
Rader, D.J.2
Muller, D.W.3
Kolansky, D.M.4
Kozarsky, K.5
Clark III, B.J.6
Stein, E.A.7
Lupien, P.J.8
Brewer Jr., H.B.9
Raper, S.E.10
-
29
-
-
0028292602
-
Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia
-
Grossman, M., Raper, S. E., Kozarsky, K., Stein, E. A., Engelhardt, J. F., Muller, D., Lupien, P. J. and Wilson, J. M. (1994) Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. Nat. Genet., 6: 335-341.
-
(1994)
Nat. Genet.
, vol.6
, pp. 335-341
-
-
Grossman, M.1
Raper, S.E.2
Kozarsky, K.3
Stein, E.A.4
Engelhardt, J.F.5
Muller, D.6
Lupien, P.J.7
Wilson, J.M.8
-
30
-
-
0034705105
-
A phage integrase directs efficient site-specific integration in human cells
-
Groth, A. C., Olivares, E. C., Thyagarajan, B. and Calos, M. P. (2000) A phage integrase directs efficient site-specific integration in human cells. Proc. Natl. Acad. Sci. U S. A., 97: 5995-6000.
-
(2000)
Proc. Natl. Acad. Sci. U S. A.
, vol.97
, pp. 5995-6000
-
-
Groth, A.C.1
Olivares, E.C.2
Thyagarajan, B.3
Calos, M.P.4
-
31
-
-
28844495614
-
Immune responses to repetitive adenovirus-mediated gene transfer and restoration of gene expression by cyclophosphamide or etoposide
-
Hamada, K., Sakaue, M., Sarkar, A., Buchl, S., Satterfield, W., Keeling, M., Sastry, J., Roth, J. A. and Follen, M. (2005) Immune responses to repetitive adenovirus-mediated gene transfer and restoration of gene expression by cyclophosphamide or etoposide. Gynecol. Oncol., 99: S177-S186.
-
(2005)
Gynecol. Oncol.
, vol.99
-
-
Hamada, K.1
Sakaue, M.2
Sarkar, A.3
Buchl, S.4
Satterfield, W.5
Keeling, M.6
Sastry, J.7
Roth, J.A.8
Follen, M.9
-
32
-
-
0032751795
-
Nonphysiological overexpression of low-density lipoprotein receptors causes pathological intracellular lipid accumulation and the formation of cholesterol and cholesteryl ester crystals in vitro
-
Heeren, J., Steinwaerder, D. S., Schnieders, F., Cichon, G., Strauss, M. and Beisiegel, U. (1999) Nonphysiological overexpression of low-density lipoprotein receptors causes pathological intracellular lipid accumulation and the formation of cholesterol and cholesteryl ester crystals in vitro. J. Mol. Med., 77: 735-743.
-
(1999)
J. Mol. Med.
, vol.77
, pp. 735-743
-
-
Heeren, J.1
Steinwaerder, D.S.2
Schnieders, F.3
Cichon, G.4
Strauss, M.5
Beisiegel, U.6
-
33
-
-
0027409026
-
Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice
-
Herz, J. and Gerard, R. D. (1993) Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc. Natl. Acad. Sci. U. S. A., 90: 2812-2816.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 2812-2816
-
-
Herz, J.1
Gerard, R.D.2
-
34
-
-
33744972320
-
Overexpression of apolipoprotein AV in the liver reduces plasma triglyceride and cholesterol but not HDL in ApoE deficient mice
-
Huang, W., Bi, N., Zhang, X., Wang, Y., Chen, B. and Liu, G. (2006) Overexpression of apolipoprotein AV in the liver reduces plasma triglyceride and cholesterol but not HDL in ApoE deficient mice. Biochem. Biophys. Res. Commun., 346: 14-18.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.346
, pp. 14-18
-
-
Huang, W.1
Bi, N.2
Zhang, X.3
Wang, Y.4
Chen, B.5
Liu, G.6
-
35
-
-
0027258140
-
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
-
Ishibashi, S., Brown, M. S., Goldstein, J. L., Gerard, R. D., Hammer, R. E. and Herz, J. (1993) Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest., 92: 883-893.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 883-893
-
-
Ishibashi, S.1
Brown, M.S.2
Goldstein, J.L.3
Gerard, R.D.4
Hammer, R.E.5
Herz, J.6
-
36
-
-
1342311458
-
Sleeping beauty transposition: Biology and applications for molecular therapy
-
Izsvak, Z. and Ivics, Z. (2004) Sleeping beauty transposition: biology and applications for molecular therapy. Mol. Ther., 9: 147-156.
-
(2004)
Mol. Ther.
, vol.9
, pp. 147-156
-
-
Izsvak, Z.1
Ivics, Z.2
-
37
-
-
2342619607
-
Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy
-
Kankkonen, H. M., Vahakangas, E., Marr, R. A., Pakkanen, T., Laurema, A., Leppanen, P., Jalkanen, J., Verma, I. M. and Yla-Herttuala, S. (2004) Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy. Mol. Ther., 9: 548-556.
-
(2004)
Mol. Ther.
, vol.9
, pp. 548-556
-
-
Kankkonen, H.M.1
Vahakangas, E.2
Marr, R.A.3
Pakkanen, T.4
Laurema, A.5
Leppanen, P.6
Jalkanen, J.7
Verma, I.M.8
Yla-Herttuala, S.9
-
38
-
-
33750207033
-
Potent reduction of apolipoprotein B and LDL cholesterol by an antisense inhibitor of apolipoprotein B
-
Kastelein, J. J. P., Wedel, M. K., Baker, B. F., Su, J., Bradley, J. D., Yu, R. Z., Chuang, E., Graham, M. J. and Crooke, R. M. (2006) Potent reduction of apolipoprotein B and LDL cholesterol by an antisense inhibitor of apolipoprotein B. Circulation, 114: 1729-1735.
-
(2006)
Circulation
, vol.114
, pp. 1729-1735
-
-
Kastelein, J.J.P.1
Wedel, M.K.2
Baker, B.F.3
Su, J.4
Bradley, J.D.5
Yu, R.Z.6
Chuang, E.7
Graham, M.J.8
Crooke, R.M.9
-
39
-
-
0022755722
-
DNA-mediated transfer of a human gene required for low-density lipoprotein receptor expression and for multiple Golgi processing pathways
-
Kingsley, D. M., Sege, R. D., Kozarsky, K. F. and Krieger, M. (1986) DNA-mediated transfer of a human gene required for low-density lipoprotein receptor expression and for multiple Golgi processing pathways. Mol. Cell Biol., 6: 2734-2737.
-
(1986)
Mol. Cell Biol.
, vol.6
, pp. 2734-2737
-
-
Kingsley, D.M.1
Sege, R.D.2
Kozarsky, K.F.3
Krieger, M.4
-
40
-
-
33847388942
-
Long-term and high level hepatic apoA-I expression using vectors based on adenoassociated virus 7 and 8
-
Kitajima, K., Miller, G. C., Gao, G., Marchadier, D. H., Wilson, J. M. and Rader, D. J. (2005) Long-term and high level hepatic apoA-I expression using vectors based on adenoassociated virus 7 and 8. Circulation, 112: II-178-II-179.
-
(2005)
Circulation
, vol.112
-
-
Kitajima, K.1
Miller, G.C.2
Gao, G.3
Marchadier, D.H.4
Wilson, J.M.5
Rader, D.J.6
-
41
-
-
0029962807
-
Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor
-
Kobayashi, K., Oka, K., Forte, T., Ishida, B., Teng, B., Ishimura-Oka, K., Nakamuta, M. and Chan, L. (1996) Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor. J. Biol. Chem., 271: 6852-6860.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6852-6860
-
-
Kobayashi, K.1
Oka, K.2
Forte, T.3
Ishida, B.4
Teng, B.5
Ishimura-Oka, K.6
Nakamuta, M.7
Chan, L.8
-
42
-
-
0027968134
-
Adenovirus-mediated transfer of a gene encoding human apolipoprotein A-I into normal mice increases circulating high-density lipoprotein cholesterol
-
Kopfler, W. P., Willard, M., Betz, T., Willard, J. E., Gerard, R. D. and Meidell, R. S. (1994) Adenovirus-mediated transfer of a gene encoding human apolipoprotein A-I into normal mice increases circulating high-density lipoprotein cholesterol. Circulation, 90: 1319-1327.
-
(1994)
Circulation
, vol.90
, pp. 1319-1327
-
-
Kopfler, W.P.1
Willard, M.2
Betz, T.3
Willard, J.E.4
Gerard, R.D.5
Meidell, R.S.6
-
43
-
-
0029936990
-
Hepatic expression of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (apobec-1) ameliorates hypercholesterolemia in LDL receptor-deficient rabbits
-
Kozarsky, K. F., Bonen, D. K., Giannoni, F., Funahashi, T., Wilson, J. M. and Davidson, N. O. (1996a) Hepatic expression of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (apobec-1) ameliorates hypercholesterolemia in LDL receptor-deficient rabbits. Hum. Gene Ther., 7: 943-957.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 943-957
-
-
Kozarsky, K.F.1
Bonen, D.K.2
Giannoni, F.3
Funahashi, T.4
Wilson, J.M.5
Davidson, N.O.6
-
44
-
-
0029988465
-
Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene
-
Kozarsky, K. F., Jooss, K., Donahee, M., Strauss, J. F. III. and Wilson, J. M. (1996b) Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene. Nat. Genet., 13: 54-62.
-
(1996)
Nat. Genet.
, vol.13
, pp. 54-62
-
-
Kozarsky, K.F.1
Jooss, K.2
Donahee, M.3
Strauss III, J.F.4
Wilson, J.M.5
-
45
-
-
0028234357
-
In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
-
Kozarsky, K. F., McKinley, D. R., Austin, L. L., Raper, S. E., Stratford-Perricaudet, L. D. and Wilson, J. M. (1994) In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. J. Biol. Chem., 269: 13695-13702.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13695-13702
-
-
Kozarsky, K.F.1
McKinley, D.R.2
Austin, L.L.3
Raper, S.E.4
Stratford-Perricaudet, L.D.5
Wilson, J.M.6
-
46
-
-
6344275675
-
Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia
-
Lebherz, C., Gao, G., Louboutin, J. P., Millar, J., Rader, D. and Wilson, J. M. (2004) Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia. J. Gene Med., 6: 663-672.
-
(2004)
J. Gene Med.
, vol.6
, pp. 663-672
-
-
Lebherz, C.1
Gao, G.2
Louboutin, J.P.3
Millar, J.4
Rader, D.5
Wilson, J.M.6
-
47
-
-
0028984818
-
Retroviral-mediated gene transfer and expression of human lipoprotein lipase in somatic cells
-
Lewis, M. E., Forsythe, I. J., Marth, J. D., Brunzell, J. D., Hayden, M. R. and Humphries, R. K. (1995) Retroviral-mediated gene transfer and expression of human lipoprotein lipase in somatic cells. Hum. Gene Ther., 6: 853-863.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 853-863
-
-
Lewis, M.E.1
Forsythe, I.J.2
Marth, J.D.3
Brunzell, J.D.4
Hayden, M.R.5
Humphries, R.K.6
-
48
-
-
0028831356
-
In vivo gene therapy for hyperlipidemia: Phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene
-
Li, J., Fang, B., Eisensmith, R. C., Li, X. H. Nasonkin, I., Lin-Lee, Y. C., Mims, M. P., Hughes, A., Montgomery, C. D., Roberts, J. D. (1995) In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene. J. Clin. Invest., 95: 768-773.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 768-773
-
-
Li, J.1
Fang, B.2
Eisensmith, R.C.3
Li, X.H.4
Nasonkin, I.5
Lin-Lee, Y.C.6
Mims, M.P.7
Hughes, A.8
Montgomery, C.D.9
Roberts, J.D.10
-
49
-
-
33646097693
-
Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA
-
Liao, W. and Ning, G. (2006) Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA. Biochem. Biophys. Res. Commun., 344: 478-483.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.344
, pp. 478-483
-
-
Liao, W.1
Ning, G.2
-
50
-
-
0033962912
-
Phenotypic correction of feline lipoprotein lipase deficiency by adenoviral gene transfer
-
Liu, G., Ashbourne Excoffon, K. J., Wilson, J. E., McManus, B. M., Rogers, Q. R., Miao, L., Kastelein, J. J., Lewis, M. E. and Hayden, M. R. (2000) Phenotypic correction of feline lipoprotein lipase deficiency by adenoviral gene transfer. Hum. Gene Ther., 11: 21-32.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 21-32
-
-
Liu, G.1
Ashbourne Excoffon, K.J.2
Wilson, J.E.3
McManus, B.M.4
Rogers, Q.R.5
Miao, L.6
Kastelein, J.J.7
Lewis, M.E.8
Hayden, M.R.9
-
51
-
-
16944362700
-
Efficient adenovirus-mediated ectopic gene expression of human lipoprotein lipase in human hepatic (HepG2) cells
-
Liu, G., Excoffon, K. J., Benoit, P., Ginzinger, D. G., Miao, L., Ehrenborg, E., Duverger, N., Denefle, P. P., Hayden, M. R. and Lewis, M. E. (1997) Efficient adenovirus-mediated ectopic gene expression of human lipoprotein lipase in human hepatic (HepG2) cells. Hum. Gene Ther., 8: 205-214.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 205-214
-
-
Liu, G.1
Excoffon, K.J.2
Benoit, P.3
Ginzinger, D.G.4
Miao, L.5
Ehrenborg, E.6
Duverger, N.7
Denefle, P.P.8
Hayden, M.R.9
Lewis, M.E.10
-
52
-
-
7844227671
-
Enhanced lipolysis in normal mice expressing liver-derived human lipoprotein lipase after adenoviral gene transfer
-
Liu, G., Excoffon, K. J., Wilson, J. E., McManus, B. M., Miao, L., Benoit, P., Duverger, N., Branellec, D., Denefle, P., Hayden, M. R. and Lewis, M. E. (1998) Enhanced lipolysis in normal mice expressing liver-derived human lipoprotein lipase after adenoviral gene transfer. Clin. Invest. Med., 21: 172-185.
-
(1998)
Clin. Invest. Med.
, vol.21
, pp. 172-185
-
-
Liu, G.1
Excoffon, K.J.2
Wilson, J.E.3
McManus, B.M.4
Miao, L.5
Benoit, P.6
Duverger, N.7
Branellec, D.8
Denefle, P.9
Hayden, M.R.10
Lewis, M.E.11
-
53
-
-
33746438424
-
Toxicity of cationic lipids and cationic polymers in gene delivery
-
Lv, H., Zhang, S., Wang, B., Cui, S. and Yan, J. (2006) Toxicity of cationic lipids and cationic polymers in gene delivery. J. Control. Release., 114: 100-109.
-
(2006)
J. Control. Release.
, vol.114
, pp. 100-109
-
-
Lv, H.1
Zhang, S.2
Wang, B.3
Cui, S.4
Yan, J.5
-
54
-
-
33744776646
-
Aggressive Very Low-Density Lipoprotein (VLDL) and LDL Lowering by Gene Transfer of the VLDL Receptor Combined with a Low-Fat Diet Regimen Induces Regression and Reduces Macrophage Content in Advanced Atherosclerotic Lesions in LDL Receptor-Deficient Mice
-
MacDougall, E. D., Kramer, F., Polinsky, P., Barnhart, S., Askari, B., Johansson, F., Varon, R., Rosenfeld, M. E., Oka, K., Chan, L., Schwartz, S. M. and Bornfeldt, K. E. (2006) Aggressive Very Low-Density Lipoprotein (VLDL) and LDL Lowering by Gene Transfer of the VLDL Receptor Combined with a Low-Fat Diet Regimen Induces Regression and Reduces Macrophage Content in Advanced Atherosclerotic Lesions in LDL Receptor-Deficient Mice. Am. J. Pathol., 168: 2064-2073.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 2064-2073
-
-
MacDougall, E.D.1
Kramer, F.2
Polinsky, P.3
Barnhart, S.4
Askari, B.5
Johansson, F.6
Varon, R.7
Rosenfeld, M.E.8
Oka, K.9
Chan, L.10
Schwartz, S.M.11
Bornfeldt, K.E.12
-
55
-
-
0032031816
-
Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectors
-
Manning, W. C., Zhou, S., Bland, M. P., Escobedo, J. A. and Dwarki, V. (1998) Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectors. Hum. Gene Ther., 9: 477-485.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 477-485
-
-
Manning, W.C.1
Zhou, S.2
Bland, M.P.3
Escobedo, J.A.4
Dwarki, V.5
-
56
-
-
33644820684
-
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
-
Manno, C. S., Pierce, G. F., Arruda, V. R., Glader, B., Ragni, M., Rasko, J. J., Ozelo, M. C., Hoots, K., Blatt, P., Konkle, B., Dake, M., Kaye, R., Razavi, M., Zajko, A., Zehnder, J., Rustagi, P. K., Nakai, H., Chew, A., Leonard, D., Wright, J. F., Lessard, R. R., Sommer, J. M., Tigges, M., Sabatino, D., Luk, A., Jiang, H., Mingozzi, F., Couto, L., Ertl, H. C, High, K. A. and Kay, M. A. (2006) Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat. Med., 12: 342-347.
-
(2006)
Nat. Med.
, vol.12
, pp. 342-347
-
-
Manno, C.S.1
Pierce, G.F.2
Arruda, V.R.3
Glader, B.4
Ragni, M.5
Rasko, J.J.6
Ozelo, M.C.7
Hoots, K.8
Blatt, P.9
Konkle, B.10
Dake, M.11
Kaye, R.12
Razavi, M.13
Zajko, A.14
Zehnder, J.15
Rustagi, P.K.16
Nakai, H.17
Chew, A.18
Leonard, D.19
Wright, J.F.20
Lessard, R.R.21
Sommer, J.M.22
Tigges, M.23
Sabatino, D.24
Luk, A.25
Jiang, H.26
Mingozzi, F.27
Couto, L.28
Ertl, H.C.29
High, K.A.30
Kay, M.A.31
more..
-
57
-
-
26444617632
-
Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment
-
Marcais, C., Verges, B., Charriere, S., Pruneta, V., Merlin, M., Billon, S., Perrot, L., Drai, J., Sassolas, A., Pennacchio, L. A., Fruchart-Najib, J., Fruchart, J. C., Durlach, V. and Moulin, P. (2005) Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment. J. Clin. Invest., 115: 2862-2869.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2862-2869
-
-
Marcais, C.1
Verges, B.2
Charriere, S.3
Pruneta, V.4
Merlin, M.5
Billon, S.6
Perrot, L.7
Drai, J.8
Sassolas, A.9
Pennacchio, L.A.10
Fruchart-Najib, J.11
Fruchart, J.C.12
Durlach, V.13
Moulin, P.14
-
58
-
-
0346777307
-
Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo
-
McCarty, D. M., Fu, H., Monahan, P. E., Toulson, C. E., Naik, P. and Samulski, R. J. (2003) Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo. Gene Ther., 10: 2112-2118.
-
(2003)
Gene Ther.
, vol.10
, pp. 2112-2118
-
-
McCarty, D.M.1
Fu, H.2
Monahan, P.E.3
Toulson, C.E.4
Naik, P.5
Samulski, R.J.6
-
59
-
-
22944488895
-
Genetic manipulation of human embryonic stem cells: A system to study early human development and potential therapeutic applications
-
Menendez, P., Wang, L. and Bhatia, M. (2005) Genetic manipulation of human embryonic stem cells: a system to study early human development and potential therapeutic applications. Curr. Gene Ther., 5: 375-385.
-
(2005)
Curr. Gene Ther.
, vol.5
, pp. 375-385
-
-
Menendez, P.1
Wang, L.2
Bhatia, M.3
-
60
-
-
0037380627
-
Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis
-
Mertens, A., Verhamme, P., Bielicki, J. K., Phillips, M. C., Quarck, R., Verreth, W., Stengel, D., Ninio, E., Navab, M., Mackness, B., Mackness, M. and Holvoet, P. (2003) Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis. Circulation, 107: 1640-1646.
-
(2003)
Circulation
, vol.107
, pp. 1640-1646
-
-
Mertens, A.1
Verhamme, P.2
Bielicki, J.K.3
Phillips, M.C.4
Quarck, R.5
Verreth, W.6
Stengel, D.7
Ninio, E.8
Navab, M.9
Mackness, B.10
Mackness, M.11
Holvoet, P.12
-
61
-
-
25144498733
-
A novel gene expression system: Non-viral gene transfer for hemophilia as model systems
-
Miao, C. H. (2005) A novel gene expression system: non-viral gene transfer for hemophilia as model systems. Adv. Genet., 54: 143-177.
-
(2005)
Adv. Genet.
, vol.54
, pp. 143-177
-
-
Miao, C.H.1
-
62
-
-
0345585159
-
Efficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro
-
Miyanohara, A., Sharkey, M. F., Witztum, J. L., Steinberg, D. and Friedmann, T. (1988) Efficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro. Proc. Natl. Acad. Sci. U. S. A., 85: 6538-6542.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 6538-6542
-
-
Miyanohara, A.1
Sharkey, M.F.2
Witztum, J.L.3
Steinberg, D.4
Friedmann, T.5
-
63
-
-
4043093508
-
Current management of severe homozygous hypercholesterolaemias
-
Naoumova, R. P., Thompson, G. R. and Soutar, A. K. (2004) Current management of severe homozygous hypercholesterolaemias. Curr. Opin. Lipidol., 15: 413-422.
-
(2004)
Curr. Opin. Lipidol.
, vol.15
, pp. 413-422
-
-
Naoumova, R.P.1
Thompson, G.R.2
Soutar, A.K.3
-
64
-
-
33847339776
-
Safe and efficient transduction of the liver after peripheral vein infusion of self complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates
-
In press
-
Nathwani, A. C., Gray, J. T., McIntosh, J., Ng, C. Y., Zhou, J., Spence, Y., Cochrane, M., Gray, E., Tuddenham, E. G. and Davidoff, A. M. (2006) Safe and efficient transduction of the liver after peripheral vein infusion of self complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates. Blood In press.
-
(2006)
Blood
-
-
Nathwani, A.C.1
Gray, J.T.2
McIntosh, J.3
Ng, C.Y.4
Zhou, J.5
Spence, Y.6
Cochrane, M.7
Gray, E.8
Tuddenham, E.G.9
Davidoff, A.M.10
-
65
-
-
5444276005
-
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia
-
Nomura, S., Merched, A., Nour, E., Dieker, C., Oka, K. and Chan, L. (2004) Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia. Gene Ther., 11: 1540-1548.
-
(2004)
Gene Ther.
, vol.11
, pp. 1540-1548
-
-
Nomura, S.1
Merched, A.2
Nour, E.3
Dieker, C.4
Oka, K.5
Chan, L.6
-
66
-
-
0033587174
-
PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo
-
O'Riordan, C. R., Lachapelle, A., Delgado, C., Parkes, V., Wadsworth, S. C., Smith, A. E. and Francis, G. E. (1999) PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo. Hum. Gene Ther., 10: 1349-1358.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1349-1358
-
-
O'Riordan, C.R.1
Lachapelle, A.2
Delgado, C.3
Parkes, V.4
Wadsworth, S.C.5
Smith, A.E.6
Francis, G.E.7
-
67
-
-
33847373814
-
Sustained phenotypic correction in a mouse model of hypoalphalipoproteinemia with a helper-dependent adenovirus vector
-
In press
-
Oka, K., Belalcazar, L. M., Dieker, C., Nour, E. A., Nuno-Gonzalez, P., Paul, A., Cormier, S., Shin, J. K., Finegold, M. and Chan, L. (2006) Sustained phenotypic correction in a mouse model of hypoalphalipoproteinemia with a helper-dependent adenovirus vector. Gene Ther, In press.
-
(2006)
Gene Ther
-
-
Oka, K.1
Belalcazar, L.M.2
Dieker, C.3
Nour, E.A.4
Nuno-Gonzalez, P.5
Paul, A.6
Cormier, S.7
Shin, J.K.8
Finegold, M.9
Chan, L.10
-
68
-
-
0035814955
-
Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor
-
Oka, K., Pastore, L., Kim, I. H., Merched, A., Nomura, S., Lee, H. J., Merched-Sauvage, M., Arden-Riley, C., Lee, B., Finegold, M., Beaudet, A. and Chan, L. (2001) Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor. Circulation, 103: 1274-1281.
-
(2001)
Circulation
, vol.103
, pp. 1274-1281
-
-
Oka, K.1
Pastore, L.2
Kim, I.H.3
Merched, A.4
Nomura, S.5
Lee, H.J.6
Merched-Sauvage, M.7
Arden-Riley, C.8
Lee, B.9
Finegold, M.10
Beaudet, A.11
Chan, L.12
-
69
-
-
33746576463
-
A novel sequence variant in APOA5 gene found in patients with severe hypertriglyceridemia
-
Oliva, C. P., Pisciotta, L., Guardamagna, O., Bellocchio, A., Tarugi, P., Schaap, F. G., Bertolini, S. and Calandra, S. (2006) A novel sequence variant in APOA5 gene found in patients with severe hypertriglyceridemia. Atherosclerosis, 188: 215-217.
-
(2006)
Atherosclerosis
, vol.188
, pp. 215-217
-
-
Oliva, C.P.1
Pisciotta, L.2
Guardamagna, O.3
Bellocchio, A.4
Tarugi, P.5
Schaap, F.G.6
Bertolini, S.7
Calandra, S.8
-
70
-
-
19944431083
-
Inherited Apolipoprotein A-V Deficiency in Severe Hypertriglyceridemia
-
Oliva, C. P., Pisciotta, L., Li, V. G., Sambataro, M. P., Cantafora, A., Bellocchio, A., Catapano, A., Tarugi, P., Bertolini, S. and Calandra, S. (2004) Inherited Apolipoprotein A-V Deficiency in Severe Hypertriglyceridemia. Arterioscler. Thromb. Vasc. Biol., 25: 411-417.
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 411-417
-
-
Oliva, C.P.1
Pisciotta, L.2
Li, V.G.3
Sambataro, M.P.4
Cantafora, A.5
Bellocchio, A.6
Catapano, A.7
Tarugi, P.8
Bertolini, S.9
Calandra, S.10
-
71
-
-
0029042918
-
Efficient retroviral-mediated gene transfer into primary culture of murine and human hepatocytes: Expression of the LDL receptor
-
Pages, J. C., Andreoletti, M., Bennoun, M., Vons, C., Elcheroth, J., Lehn, P., Houssin, D., Chapman, J., Briand, P., Benarous, R. (1995) Efficient retroviral-mediated gene transfer into primary culture of murine and human hepatocytes: expression of the LDL receptor. Hum. Gene Ther., 6: 21-30.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 21-30
-
-
Pages, J.C.1
Andreoletti, M.2
Bennoun, M.3
Vons, C.4
Elcheroth, J.5
Lehn, P.6
Houssin, D.7
Chapman, J.8
Briand, P.9
Benarous, R.10
-
72
-
-
6544243305
-
Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase-ganciclovir treatment
-
Pakkanen, T. M., Laitinen, M., Hippelainen, M., Kallionpaa, H., Lehtolainen, P., Leppanen, P., Luoma, J. S., Tarvainen, R., Alhava, E. and Yla-Herttuala, S. (1999) Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase-ganciclovir treatment. Gene Ther., 6: 34-41.
-
(1999)
Gene Ther
, vol.6
, pp. 34-41
-
-
Pakkanen, T.M.1
Laitinen, M.2
Hippelainen, M.3
Kallionpaa, H.4
Lehtolainen, P.5
Leppanen, P.6
Luoma, J.S.7
Tarvainen, R.8
Alhava, E.9
Yla-Herttuala, S.10
-
73
-
-
0032827780
-
Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration
-
Parks, R., Evelegh, C. and Graham, F. (1999) Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration. Gene Ther., 6: 1565-1573.
-
(1999)
Gene Ther
, vol.6
, pp. 1565-1573
-
-
Parks, R.1
Evelegh, C.2
Graham, F.3
-
74
-
-
1242338802
-
Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein A-I reduces atherosclerosis in apo E-deficient mice
-
Pastore, L., Belalcazar, L. M., Oka, K., Cela, R., Lee, B., Chan, L. and Beaudet, A. L. (2004) Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein A-I reduces atherosclerosis in apo E-deficient mice. Gene, 327: 153-160.
-
(2004)
Gene
, vol.327
, pp. 153-160
-
-
Pastore, L.1
Belalcazar, L.M.2
Oka, K.3
Cela, R.4
Lee, B.5
Chan, L.6
Beaudet, A.L.7
-
75
-
-
0035812707
-
An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing
-
Pennacchio, L. A., Olivier, M., Hubacek, J. A., Cohen, J. C, Cox, D. R., Fruchart, J. C., Krauss, R. M. and Rubin, E. M. (2001) An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science, 294: 169-173.
-
(2001)
Science
, vol.294
, pp. 169-173
-
-
Pennacchio, L.A.1
Olivier, M.2
Hubacek, J.A.3
Cohen, J.C.4
Cox, D.R.5
Fruchart, J.C.6
Krauss, R.M.7
Rubin, E.M.8
-
76
-
-
0037625120
-
Genetic disorders of lecithin: Cholesterol acytransferase
-
In: Eds. Betteridge, D.J, Illingworth, D.R. and Shepherd, J. Oxford University Press, New York
-
Pritchard, P. H. and Hill, J. S. (1999) Genetic disorders of lecithin: cholesterol acytransferase. In: Lipoproteins in health and disease, Eds. Betteridge, D.J, Illingworth, D.R. and Shepherd, J. Oxford University Press, New York, pp. 799-814.
-
(1999)
Lipoproteins in Health and Disease
, pp. 799-814
-
-
Pritchard, P.H.1
Hill, J.S.2
-
77
-
-
14744292260
-
Low-density lipoprotein (LDL) receptor/transferrin fusion protein: In vivo production and functional evaluation as a potential therapeutic tool for lowering plasma LDL cholesterol
-
Razzini, G., Parise, F., Calebiro, D., Battini, R., Bagni, B., Corazzari, T., Tarugi, P., Angelelli, C., Molinari, S., Falqui, L. and Ferrari, S. (2004) Low-density lipoprotein (LDL) receptor/transferrin fusion protein: in vivo production and functional evaluation as a potential therapeutic tool for lowering plasma LDL cholesterol. Hum. Gene Ther., 15: 533-541.
-
(2004)
Hum. Gene Ther.
, vol.15
, pp. 533-541
-
-
Razzini, G.1
Parise, F.2
Calebiro, D.3
Battini, R.4
Bagni, B.5
Corazzari, T.6
Tarugi, P.7
Angelelli, C.8
Molinari, S.9
Falqui, L.10
Ferrari, S.11
-
78
-
-
0035856577
-
In vivo studies of HDL assembly and metabolism using adenovirus-mediated transfer of ApoA-I mutants in ApoA-I-deficient mice
-
Reardon, C. A., Kan, H. Y., Cabana, V., Blachowicz, L., Lukens, J. R., Wu, Q., Liadaki, K., Getz, G. S. and Zannis, V. I. (2001) In vivo studies of HDL assembly and metabolism using adenovirus-mediated transfer of ApoA-I mutants in ApoA-I-deficient mice. Biochemistry, 40: 13670-13680.
-
(2001)
Biochemistry
, vol.40
, pp. 13670-13680
-
-
Reardon, C.A.1
Kan, H.Y.2
Cabana, V.3
Blachowicz, L.4
Lukens, J.R.5
Wu, Q.6
Liadaki, K.7
Getz, G.S.8
Zannis, V.I.9
-
79
-
-
33745039813
-
Lipoprotein lipase S447X: A naturally occurring gain-of-function mutation
-
Rip, J., Nierman, M. C., Ross, C. J., Jukema, J. W., Hayden, M. R., Kastelein, J. J., Stroes, E. S. and Kuivenhoven, J. A. (2006) Lipoprotein lipase S447X: a naturally occurring gain-of-function mutation. Arterioscler. Thromb. Vasc. Biol., 26: 1236-1245.
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 1236-1245
-
-
Rip, J.1
Nierman, M.C.2
Ross, C.J.3
Jukema, J.W.4
Hayden, M.R.5
Kastelein, J.J.6
Stroes, E.S.7
Kuivenhoven, J.A.8
-
80
-
-
27744446128
-
Gene therapy for lipoprotein lipase deficiency: Working toward clinical application
-
Rip, J., Nierman, M. C., Sierts, J. A., Petersen, W., van den, O. K., Van Raalte, D., Ross, C. J., Hayden, M. R., Bakker, A. C., Dijkhuizen, P., Hermens, W. T., Twisk, J., Stroes, E., Kastelein, J. J., Kuivenhoven, J. A. and Meulenberg, J. M. (2005) Gene therapy for lipoprotein lipase deficiency: working toward clinical application. Hum. Gene Ther., 16: 1276-1286.
-
(2005)
Hum. Gene Ther.
, vol.16
, pp. 1276-1286
-
-
Rip, J.1
Nierman, M.C.2
Sierts, J.A.3
Petersen, W.4
van Den, O.K.5
Van Raalte, D.6
Ross, C.J.7
Hayden, M.R.8
Bakker, A.C.9
Dijkhuizen, P.10
Hermens, W.T.11
Twisk, J.12
Stroes, E.13
Kastelein, J.J.14
Kuivenhoven, J.A.15
Meulenberg, J.M.16
-
81
-
-
26244445992
-
Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation
-
Ross, C. J., Liu, G., Kuivenhoven, J. A., Twisk, J., Rip, J., van Dop, W., Excoffon, K. J., Lewis, S. M., Kastelein, J. J. and Hayden, M. R. (2005) Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation. Arterioscler. Thromb. Vasc. Biol., 25: 2143-2150.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2143-2150
-
-
Ross, C.J.1
Liu, G.2
Kuivenhoven, J.A.3
Twisk, J.4
Rip, J.5
van Dop, W.6
Excoffon, K.J.7
Lewis, S.M.8
Kastelein, J.J.9
Hayden, M.R.10
-
82
-
-
33646933211
-
Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation
-
Ross, C. J., Twisk, J., Bakker, A. C., Miao, F., Verbart, D., Rip, J., Godbey, T., Dijkhuizen, P., Hermens, W. T., Kastelein, J. J., Kuivenhoven, J. A, Meulenberg, J. M. and Hayden, M. R. (2006) Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation. Hum. Gene Ther., 17: 487-499.
-
(2006)
Hum. Gene Ther.
, vol.17
, pp. 487-499
-
-
Ross, C.J.1
Twisk, J.2
Bakker, A.C.3
Miao, F.4
Verbart, D.5
Rip, J.6
Godbey, T.7
Dijkhuizen, P.8
Hermens, W.T.9
Kastelein, J.J.10
Kuivenhoven, J.A.11
Meulenberg, J.M.12
Hayden, M.R.13
-
83
-
-
4544326444
-
Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation
-
Ross, C. J., Twisk, J., Meulenberg, J. M., Liu, G., van den, O. K., Moraal, E., Hermens, W. T., Rip, J., Kastelein, J. J., Kuivenhoven, J. A. and Hayden, M. R. (2004) Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation. Hum. Gene Ther., 15: 906-919.
-
(2004)
Hum. Gene Ther.
, vol.15
, pp. 906-919
-
-
Ross, C.J.1
Twisk, J.2
Meulenberg, J.M.3
Liu, G.4
van den, O.K.5
Moraal, E.6
Hermens, W.T.7
Rip, J.8
Kastelein, J.J.9
Kuivenhoven, J.A.10
Hayden, M.R.11
-
84
-
-
3142581525
-
ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
-
Schaap, F. G., Rensen, P. C., Voshol, P. J., Vrins, C., van der Vliet, H. N., Chamuleau, R. A., Havekes, L. M., Groen, A. K. and van Dijk, K. W. (2004) ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis. J. Biol. Chem., 279: 27941-27947.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27941-27947
-
-
Schaap, F.G.1
Rensen, P.C.2
Voshol, P.J.3
Vrins, C.4
van der Vliet, H.N.5
Chamuleau, R.A.6
Havekes, L.M.7
Groen, A.K.8
van Dijk, K.W.9
-
85
-
-
0029845121
-
Potential gene therapy for lecithin-cholesterol acyltransferase (LCAT)-deficient and hypoalphalipoproteinemic patients with adenovirus-mediated transfer of human LCAT gene
-
Seguret-Mace, S., Latta-Mahieu, M., Castro, G., Luc, G., Fruchart, J. C., Rubin, E., Denefle, P. and Duverger, N. (1996) Potential gene therapy for lecithin-cholesterol acyltransferase (LCAT)-deficient and hypoalphalipoproteinemic patients with adenovirus-mediated transfer of human LCAT gene. Circulation, 94: 2177-2184.
-
(1996)
Circulation
, vol.94
, pp. 2177-2184
-
-
Seguret-Mace, S.1
Latta-Mahieu, M.2
Castro, G.3
Luc, G.4
Fruchart, J.C.5
Rubin, E.6
Denefle, P.7
Duverger, N.8
-
86
-
-
22544455377
-
AAV serotype-dependent apolipoprotein A-I Milano gene expression
-
Sharifi, B. G., Wu, K., Wang, L., Ong, J. M., Zhou, X. and Shah, P. K. (2005) AAV serotype-dependent apolipoprotein A-I Milano gene expression. Atherosclerosis, 181: 261-269.
-
(2005)
Atherosclerosis
, vol.181
, pp. 261-269
-
-
Sharifi, B.G.1
Wu, K.2
Wang, L.3
Ong, J.M.4
Zhou, X.5
Shah, P.K.6
-
87
-
-
0038442874
-
Intravenous gene therapy for familial hypercholesterolemia using ligand-facilitated transfer of a liposome:LDL receptor gene complex
-
Shichiri, M., Tanaka, A. and Hirata, Y. (2003) Intravenous gene therapy for familial hypercholesterolemia using ligand-facilitated transfer of a liposome:LDL receptor gene complex. Gene Ther., 10: 827-831.
-
(2003)
Gene Ther.
, vol.10
, pp. 827-831
-
-
Shichiri, M.1
Tanaka, A.2
Hirata, Y.3
-
88
-
-
0029934048
-
Transient immunosuppression permits successful repetitive intravenous administration of an adenovirus vector
-
Smith, T. A., White, B. D., Gardner, J. M., Kaleko, M. and McClelland, A. (1996) Transient immunosuppression permits successful repetitive intravenous administration of an adenovirus vector. Gene Ther., 3: 496-502.
-
(1996)
Gene Ther
, vol.3
, pp. 496-502
-
-
Smith, T.A.1
White, B.D.2
Gardner, J.M.3
Kaleko, M.4
McClelland, A.5
-
89
-
-
0029160030
-
Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol
-
Spady, D. K., Cuthbert, J. A., Willard, M. N. and Meidell, R. S. (1995) Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol. J. Clin. Invest., 96: 700-709.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 700-709
-
-
Spady, D.K.1
Cuthbert, J.A.2
Willard, M.N.3
Meidell, R.S.4
-
90
-
-
0031594714
-
Overexpression of Cholesterol 7alpha -Hydroxylase (CYP7A) in Mice Lacking the Low Density Lipoprotein (LDL) Receptor Gene. LDL transport and plasma LDL concentrations are reduced
-
Spady, D. K., Cuthbert, J. A., Willard, M. N. and Meidell, R. S. (1998) Overexpression of Cholesterol 7alpha -Hydroxylase (CYP7A) in Mice Lacking the Low Density Lipoprotein (LDL) Receptor Gene. LDL transport and plasma LDL concentrations are reduced. J. Biol. Chem., 273: 126-132.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 126-132
-
-
Spady, D.K.1
Cuthbert, J.A.2
Willard, M.N.3
Meidell, R.S.4
-
91
-
-
0033644454
-
Long-term reversal of hypercholesterolemia in low density lipoprotein receptor (LDLR)-deficient mice by adenovirus-mediated LDLR gene transfer combined with CD154 blockade
-
Stein, C. S., Martins, I. and Davidson, B. L. (2000) Long-term reversal of hypercholesterolemia in low density lipoprotein receptor (LDLR)-deficient mice by adenovirus-mediated LDLR gene transfer combined with CD154 blockade. J. Gene Med., 2: 41-51.
-
(2000)
J. Gene Med.
, vol.2
, pp. 41-51
-
-
Stein, C.S.1
Martins, I.2
Davidson, B.L.3
-
92
-
-
0035965240
-
Adenovirus-mediated rescue of lipoprotein lipase-deficient mice. Lipolysis of triglyceride-rich lipoproteins is essential for high density lipoprotein maturation in mice
-
Strauss, J. G., Frank, S., Kratky, D., Hammerle, G., Hrzenjak, A., Knipping, G., von Eckardstein, A., Kostner, G. M. and Zechner, R. (2001) Adenovirus-mediated rescue of lipoprotein lipase-deficient mice. Lipolysis of triglyceride-rich lipoproteins is essential for high density lipoprotein maturation in mice. J. Biol. Chem., 276: 36083-36090.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36083-36090
-
-
Strauss, J.G.1
Frank, S.2
Kratky, D.3
Hammerle, G.4
Hrzenjak, A.5
Knipping, G.6
von Eckardstein, A.7
Kostner, G.M.8
Zechner, R.9
-
93
-
-
0035317671
-
A novel approach to ex vivo gene therapy for familial hypercholesterolemia using human amniotic epithelial cells as a transgene carrier
-
Takahashi, S., Ohsugi, K., Yamamoto, T., Shiomi, M. and Sakuragawa, N. (2001) A novel approach to ex vivo gene therapy for familial hypercholesterolemia using human amniotic epithelial cells as a transgene carrier. Tohoku. J. Exp. Med., 193: 279-292.
-
(2001)
Tohoku. J. Exp. Med.
, vol.193
, pp. 279-292
-
-
Takahashi, S.1
Ohsugi, K.2
Yamamoto, T.3
Shiomi, M.4
Sakuragawa, N.5
-
94
-
-
0032706442
-
Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice
-
Tangirala, R. K., Tsukamoto, K., Chun, S. H., Usher, D., Pure, E. and Rader, D. J. (1999) Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice. Circulation, 100: 1816-1822.
-
(1999)
Circulation
, vol.100
, pp. 1816-1822
-
-
Tangirala, R.K.1
Tsukamoto, K.2
Chun, S.H.3
Usher, D.4
Pure, E.5
Rader, D.J.6
-
95
-
-
0028171662
-
Adenovirus-mediated gene transfer of rat apolipoprotein B mRNA-editing protein in mice virtually eliminates apolipoprotein B-100 and normal low density lipoprotein production
-
Teng, B., Blumenthal, S., Forte, T., Navaratnam, N., Scott, J., Gotto, A. M. Jr. and Chan, L. (1994) Adenovirus-mediated gene transfer of rat apolipoprotein B mRNA-editing protein in mice virtually eliminates apolipoprotein B-100 and normal low density lipoprotein production. J. Biol. Chem., 269: 29395-29404.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29395-29404
-
-
Teng, B.1
Blumenthal, S.2
Forte, T.3
Navaratnam, N.4
Scott, J.5
Gotto Jr., A.M.6
Chan, L.7
-
96
-
-
0030994487
-
Effective Lowering of Plasma, LDL. and Esterified Cholesterol in LDL ReceptorûKnockout Mice by Adenovirus-Mediated Gene Delivery of ApoB mRNA Editing Enzyme (Apobecl)
-
Teng, B., Ishida, B., Forte, T. M., Blumenthal, S., Song, L. Z., Gotto, A. M. Jr. and Chan, L. (1997) Effective Lowering of Plasma, LDL. and Esterified Cholesterol in LDL ReceptorûKnockout Mice by Adenovirus-Mediated Gene Delivery of ApoB mRNA Editing Enzyme (Apobecl). Arterioscler. Thromb. Vasc. Biol., 17: 889-897.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 889-897
-
-
Teng, B.1
Ishida, B.2
Forte, T.M.3
Blumenthal, S.4
Song, L.Z.5
Gotto Jr., A.M.6
Chan, L.7
-
97
-
-
0030863640
-
Comparison of human apoA-I expression in mouse models of atherosclerosis after gene transfer using a second generation adenovirus
-
Tsukamoto, K., Hiester, K. G., Smith, P., Usher, D. C., Glick, J. M. and Rader, D. J. (1997) Comparison of human apoA-I expression in mouse models of atherosclerosis after gene transfer using a second generation adenovirus. J. Lipid Res., 38: 1869-1876.
-
(1997)
J. Lipid Res.
, vol.38
, pp. 1869-1876
-
-
Tsukamoto, K.1
Hiester, K.G.2
Smith, P.3
Usher, D.C.4
Glick, J.M.5
Rader, D.J.6
-
98
-
-
0035977037
-
Apolipoprotein A-V: A novel apolipoprotein associated with an early phase of liver regeneration
-
van der Vliet, H. N., Sammels, M. G., Leegwater, A. C., Levels, J. H., Reitsma, P. H., Boers, W. and Chamuleau, R. A. (2001) Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration. J. Biol. Chem., 276: 44512-44520.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44512-44520
-
-
van der Vliet, H.N.1
Sammels, M.G.2
Leegwater, A.C.3
Levels, J.H.4
Reitsma, P.H.5
Boers, W.6
Chamuleau, R.A.7
-
99
-
-
0036349314
-
Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice
-
van der Vliet, H. N., Schaap, F. G., Levels, J. H., Ottenhoff, R., Looije, N., Wesseling, J. G., Groen, A. K. and Chamuleau, R. A. (2002) Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice. Biochem. Biophys. Res. Commun., 295: 1156-1159.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.295
, pp. 1156-1159
-
-
van der Vliet, H.N.1
Schaap, F.G.2
Levels, J.H.3
Ottenhoff, R.4
Looije, N.5
Wesseling, J.G.6
Groen, A.K.7
Chamuleau, R.A.8
-
100
-
-
0036252993
-
Effect of promoters and enhancers on expression, transgene DNA persistence. and hepatotoxicity after adenoviral gene transfer of human apolipoprotein A-I
-
Van Linthout, S., Collen, D. and De Geest, B. (2002a) Effect of promoters and enhancers on expression, transgene DNA persistence. and hepatotoxicity after adenoviral gene transfer of human apolipoprotein A-I. Hum. Gene. Ther., 13: 829-840.
-
(2002)
Hum. Gene. Ther.
, vol.13
, pp. 829-840
-
-
Van Linthout, S.1
Collen, D.2
De Geest, B.3
-
101
-
-
18744364150
-
Persistent hepatic expression of human apo A-I after transfer with a helper-virus independent adenoviral vector
-
Van Linthout, S., Lusky, M., Collen, D. and De Geest, B. (2002b) Persistent hepatic expression of human apo A-I after transfer with a helper-virus independent adenoviral vector. Gene Ther., 9: 1520-1528.
-
(2002)
Gene Ther.
, vol.9
, pp. 1520-1528
-
-
Van Linthout, S.1
Lusky, M.2
Collen, D.3
De Geest, B.4
-
102
-
-
0038237520
-
Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells
-
Wade-Martins, R., Saeki, Y. and Chiocca, E. A. (2003) Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells. Mol. Ther., 7: 604-612.
-
(2003)
Mol. Ther.
, vol.7
, pp. 604-612
-
-
Wade-Martins, R.1
Saeki, Y.2
Chiocca, E.A.3
-
103
-
-
0033588158
-
Hammerhead ribozyme cleavage of apolipoprotein B mRNA generates a truncated protein
-
Wang, J. P., Enjoji, M., Tiebel, M., Ochsner, S., Chan, L. and Teng, B. B. (1999) Hammerhead ribozyme cleavage of apolipoprotein B mRNA generates a truncated protein. J. Biol. Chem., 274: 24161-24170.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24161-24170
-
-
Wang, J.P.1
Enjoji, M.2
Tiebel, M.3
Ochsner, S.4
Chan, L.5
Teng, B.B.6
-
104
-
-
0242290921
-
E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models
-
Wang, Y., Hallden, G., Hill, R., Anand, A., Liu, T. C., Francis, J., Brooks, G., Lemoine, N. and Kirn, D. (2003a) E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models. Nat. Biotechnol., 21: 1328-1335.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1328-1335
-
-
Wang, Y.1
Hallden, G.2
Hill, R.3
Anand, A.4
Liu, T.C.5
Francis, J.6
Brooks, G.7
Lemoine, N.8
Kirn, D.9
-
105
-
-
0348038748
-
Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo
-
Wang, Z., Ma, H. I., Li, J., Sun, L., Zhang, J. and Xiao, X. (2003b) Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo. Gene. Ther., 10: 2105-2111.
-
(2003)
Gene. Ther.
, vol.10
, pp. 2105-2111
-
-
Wang, Z.1
Ma, H.I.2
Li, J.3
Sun, L.4
Zhang, J.5
Xiao, X.6
-
106
-
-
12444288471
-
Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1
-
Wellington, C. L., Brunham, L. R., Zhou, S., Singaraja, R. R., Visscher, H., Gelfer, A., Ross, C., James, E., Liu, G., Huber, M. T., Yang, Y. Z, Parks, R. J., Groen, A., Fruchart-Najib, J. and Hayden, M. R. (2003) Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1. J. Lipid Res., 44: 1470-1480.
-
(2003)
J. Lipid Res.
, vol.44
, pp. 1470-1480
-
-
Wellington, C.L.1
Brunham, L.R.2
Zhou, S.3
Singaraja, R.R.4
Visscher, H.5
Gelfer, A.6
Ross, C.7
James, E.8
Liu, G.9
Huber, M.T.10
Yang, Y.Z.11
Parks, R.J.12
Groen, A.13
Fruchart-Najib, J.14
Hayden, M.R.15
-
107
-
-
0025188013
-
Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes
-
Wilson, J. M., Chowdhury, N. R., Grossman, M., Wajsman, R., Epstein, A., Mulligan, R. C. and Chowdhury, J. R. (1990) Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes. Proc. Natl. Acad. Sci. U. S. A., 87: 8437-8441.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 8437-8441
-
-
Wilson, J.M.1
Chowdhury, N.R.2
Grossman, M.3
Wajsman, R.4
Epstein, A.5
Mulligan, R.C.6
Chowdhury, J.R.7
-
108
-
-
0026502766
-
Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits
-
Wilson, J. M., Grossman, M., Wu, C. H., Chowdhury, N. R., Wu, G. Y. and Chowdhury, J. R. (1992) Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits. J. Biol. Chem., 267: 963-967.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 963-967
-
-
Wilson, J.M.1
Grossman, M.2
Wu, C.H.3
Chowdhury, N.R.4
Wu, G.Y.5
Chowdhury, J.R.6
-
109
-
-
0023805807
-
Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit
-
Wilson, J. M., Johnston, D. E., Jefferson, D. M. and Mulligan, R. C. (1988) Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit. Proc. Natl. Acad. Sci. U. S. A., 85: 4421-4425.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 4421-4425
-
-
Wilson, J.M.1
Johnston, D.E.2
Jefferson, D.M.3
Mulligan, R.C.4
-
110
-
-
33746874152
-
Adeno-associated virus serotypes: Vector toolkit for human gene therapy
-
Wu, Z., Asokan, A. and Samulski, R. J. (2006) Adeno-associated virus serotypes: vector toolkit for human gene therapy. Mol. Ther., 14: 316-327.
-
(2006)
Mol. Ther.
, vol.14
, pp. 316-327
-
-
Wu, Z.1
Asokan, A.2
Samulski, R.J.3
-
111
-
-
0034986416
-
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages
-
Zhang, Y., Chirmule, N., Gao, G. P., Qian, R., Croyle, M., Joshi, B., Tazelaar, J. and Wilson, J. M. (2001) Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages. Mol. Ther., 3: 697-707.
-
(2001)
Mol. Ther.
, vol.3
, pp. 697-707
-
-
Zhang, Y.1
Chirmule, N.2
Gao, G.P.3
Qian, R.4
Croyle, M.5
Joshi, B.6
Tazelaar, J.7
Wilson, J.M.8
-
112
-
-
0041662117
-
Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo
-
Zhang, Y., Zanotti, I., Reilly, M. P., Glick, J. M., Rothblat, G. H. and Rader, D. J. (2003) Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation, 108: 661-663.
-
(2003)
Circulation
, vol.108
, pp. 661-663
-
-
Zhang, Y.1
Zanotti, I.2
Reilly, M.P.3
Glick, J.M.4
Rothblat, G.H.5
Rader, D.J.6
-
113
-
-
4243060477
-
The recombinant adeno-associated virus vector (rAAV2)-mediated apolipoprotein B mRNA-specific hammerhead ribozyme: A self-complementary AAV2 vector improves the gene expression
-
Zhong, S., Sun, S. and Teng, B. B. (2004) The recombinant adeno-associated virus vector (rAAV2)-mediated apolipoprotein B mRNA-specific hammerhead ribozyme: a self-complementary AAV2 vector improves the gene expression. Genet. Vaccines Ther., 2: 5-
-
(2004)
Genet. Vaccines Ther.
, vol.2
, pp. 5
-
-
Zhong, S.1
Sun, S.2
Teng, B.B.3
-
114
-
-
0030666462
-
Adenovirus-mediated gene transfer of human lipoprotein lipase ameliorates the hyperlipidemias associated with apolipoprotein E and LDL receptor deficiencies in mice
-
Zsigmond, E., Kobayashi, K., Tzung, K. W., Li, L., Fuke, Y. and Chan, L. (1997) Adenovirus-mediated gene transfer of human lipoprotein lipase ameliorates the hyperlipidemias associated with apolipoprotein E and LDL receptor deficiencies in mice. Hum. Gene Ther., 8: 1921-1933.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1921-1933
-
-
Zsigmond, E.1
Kobayashi, K.2
Tzung, K.W.3
Li, L.4
Fuke, Y.5
Chan, L.6
|