Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells

Molecular Therapy

Volumn 7, Issue 5, 2003, Pages 604-612

  Wade Martins, Richard ^a   Saeki, Yoshinaga ^a   Chiocca, E Antonio ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Amplicon; Bacterial artificial chromosome; Cardiovascular disease; Episomal vector; Functional genomics; Gene expression regulation; Gene transfer; Genomic DNA; Herpesvirus

Indexed keywords

COMPLEMENTARY DNA; GENOMIC DNA; LOW DENSITY LIPOPROTEIN RECEPTOR; STEROL; VIRUS VECTOR;

AMPLICON; ANIMAL CELL; BACTERIAL ARTIFICIAL CHROMOSOME; CHO CELL; CHROMOSOME INSERTION; CONTROLLED STUDY; FAMILIAL HYPERCHOLESTEROLEMIA; FIBROBLAST; GENE EXPRESSION REGULATION; GENE LOCUS; GENE TARGETING; GENE TECHNOLOGY; HERPES VIRUS; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; REVIEW; VIRAL GENE DELIVERY SYSTEM;

ANIMALIA; BACTERIA (MICROORGANISMS); CRICETINAE; CRICETULUS GRISEUS; HERPESVIRIDAE; INSERTION SEQUENCES; RODENTIA; SIMPLEXVIRUS;

EID: 0038237520     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1525-0016(03)00060-1     Document Type: Article

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