메뉴 건너뛰기




Volumn 3, Issue 6, 1996, Pages 496-502

Transient immunosuppression permits successful repetitive intravenous administration of an adenovirus vector

Author keywords

Adenovirus vector; Repeat dosing; Transient immunosuppression

Indexed keywords

15 DEOXYSPERGUALIN; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; CYCLOPHOSPHAMIDE; NEUTRALIZING ANTIBODY;

EID: 0029934048     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (122)

References (31)
  • 1
    • 0027984919 scopus 로고
    • In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung
    • Yei S et al. In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung. Hum Gene Ther 1994; 5: 731-744.
    • (1994) Hum Gene Ther , vol.5 , pp. 731-744
    • Yei, S.1
  • 2
    • 0027755939 scopus 로고
    • Adenovirus-mediated transfer of the CFTR gene to the lung of nonhuman primates: Biological efficacy study
    • Engelhardt JF et al. Adenovirus-mediated transfer of the CFTR gene to the lung of nonhuman primates: biological efficacy study. Hum Gene Ther 1993; 4: 759-769
    • (1993) Hum Gene Ther , vol.4 , pp. 759-769
    • Engelhardt, J.F.1
  • 3
    • 0027521773 scopus 로고
    • Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice
    • Smith TAG et al. Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice. Nat Genet 1993; 5. 397-402.
    • (1993) Nat Genet , vol.5 , pp. 397-402
    • Smith, T.A.G.1
  • 4
    • 0028168641 scopus 로고
    • Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
    • Crystal RG et al. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet 1994; 8: 42-51.
    • (1994) Nat Genet , vol.8 , pp. 42-51
    • Crystal, R.G.1
  • 5
    • 0028234357 scopus 로고
    • In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
    • Kozarsky KF et al. In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. J Biol Chem 1994; 269: 13695-13702.
    • (1994) J Biol Chem , vol.269 , pp. 13695-13702
    • Kozarsky, K.F.1
  • 6
    • 0028274169 scopus 로고
    • In vivo hepatic gene therapy: Complete albeit transient correction of factor IX deficiency in hemophilia B dogs
    • Kay MA et al. In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs. Proc Natl Acad Sci USA 1994, 91: 2353-2357.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2353-2357
    • Kay, M.A.1
  • 7
    • 0028429545 scopus 로고
    • Adenovirus-mediated gene transfer for cystic fibrosis: Quantitative evaluation of repeated in vivo vector administration to the lung
    • Yei S et al Adenovirus-mediated gene transfer for cystic fibrosis: quantitative evaluation of repeated in vivo vector administration to the lung. Gene Therapy 1994; 1: 192-200.
    • (1994) Gene Therapy , vol.1 , pp. 192-200
    • Yei, S.1
  • 8
    • 0028899392 scopus 로고
    • IL-6 release and airway administration of human CFTR cDNA adenovirus vector
    • McElvaney NG, Crystal RG. IL-6 release and airway administration of human CFTR cDNA adenovirus vector. Nature Med 1995; 1: 182-184.
    • (1995) Nature Med , vol.1 , pp. 182-184
    • McElvaney, N.G.1    Crystal, R.G.2
  • 9
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y, Li Q, Ertl HC, Wilson JM. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004-2015.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 10
    • 0028934815 scopus 로고
    • Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
    • Dai Y et al. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci USA 1995; 92: 1401-1405.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1401-1405
    • Dai, Y.1
  • 11
    • 0028914687 scopus 로고
    • Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: Comparisons between immunocompetent and immunodeficient inbred strains
    • Barr D et al. Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. Gene Therapy 1995; 2: 151-155.
    • (1995) Gene Therapy , vol.2 , pp. 151-155
    • Barr, D.1
  • 12
    • 0029943193 scopus 로고    scopus 로고
    • Sustained expression of therapeutic levels of human factor VIII in mice
    • in press
    • Connelly S et al. Sustained expression of therapeutic levels of human factor VIII in mice. Blood 1996; 87: (in press).
    • (1996) Blood , vol.87
    • Connelly, S.1
  • 13
    • 0028365183 scopus 로고
    • Prevention of the humoral response induced by an anti-CD3 monoclonal antibody by deoxyspergualin in a murine model
    • Alegre M et al. Prevention of the humoral response induced by an anti-CD3 monoclonal antibody by deoxyspergualin in a murine model. Transplantation 1994; 57: 1786-1794.
    • (1994) Transplantation , vol.57 , pp. 1786-1794
    • Alegre, M.1
  • 14
    • 0016699399 scopus 로고
    • The influence of cyclophosphamide on antibody formation in the mouse
    • Willers JMN, Sluis E The influence of cyclophosphamide on antibody formation in the mouse. Ann Immunol (Inst Pasteur) 1975; 126C: 267-279.
    • (1975) Ann Immunol (Inst Pasteur) , vol.126 C , pp. 267-279
    • Willers, J.M.N.1    Sluis, E.2
  • 15
    • 0027256479 scopus 로고
    • Immunosuppressive action of cyclophosphamide in mice: Contribution of some factors to determination of strain differences
    • Pukhalsky AL, Toptygina P, Viktorov VV. Immunosuppressive action of cyclophosphamide in mice: contribution of some factors to determination of strain differences. Int J Immunopharm 1993; 15: 509-514.
    • (1993) Int J Immunopharm , vol.15 , pp. 509-514
    • Pukhalsky, A.L.1    Toptygina, P.2    Viktorov, V.V.3
  • 16
    • 0027731608 scopus 로고
    • Deoxyspergualin: Mode of action and clinical trials
    • Suzuki S. Deoxyspergualin: mode of action and clinical trials. Ann NY Acad Sci 1993; 696: 263-269.
    • (1993) Ann NY Acad Sci , vol.696 , pp. 263-269
    • Suzuki, S.1
  • 18
    • 0028978493 scopus 로고
    • Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung
    • Yang Y, Trinchieri G, Wilson JM. Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung. Nature Med 1995; 1: 890-893.
    • (1995) Nature Med , vol.1 , pp. 890-893
    • Yang, Y.1    Trinchieri, G.2    Wilson, J.M.3
  • 19
    • 0029052716 scopus 로고
    • Immunomodulation to enhance gene therapy
    • Wilson C, Kay MA. Immunomodulation to enhance gene therapy. Nature Med 1995; 1: 887-889.
    • (1995) Nature Med , vol.1 , pp. 887-889
    • Wilson, C.1    Kay, M.A.2
  • 20
    • 0029154012 scopus 로고
    • Gene therapy for hemophilia: Host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression
    • Fang B et al. Gene therapy for hemophilia: host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression. Hum Gene Ther 1995; 6: 1039-1044.
    • (1995) Hum Gene Ther , vol.6 , pp. 1039-1044
    • Fang, B.1
  • 21
    • 0029113869 scopus 로고
    • Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4lg administration
    • Kay MA et al. Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4lg administration Nat Genet 1995; 11: 191-197.
    • (1995) Nat Genet , vol.11 , pp. 191-197
    • Kay, M.A.1
  • 22
    • 0027742182 scopus 로고
    • Deoxyspergualin: Mechanism of action studies of a novel immunosuppressive drug
    • Tepper MA. Deoxyspergualin: mechanism of action studies of a novel immunosuppressive drug. Ann NY Acad Sci 1993; 696: 123-132.
    • (1993) Ann NY Acad Sci , vol.696 , pp. 123-132
    • Tepper, M.A.1
  • 23
    • 0028116791 scopus 로고
    • Deoxyspergualin - A different and intriguing immunosuppressant
    • Tufveson G, Gannedahl G. Deoxyspergualin - a different and intriguing immunosuppressant. Transplant Proc 1994; 26: 3029-3039.
    • (1994) Transplant Proc , vol.26 , pp. 3029-3039
    • Tufveson, G.1    Gannedahl, G.2
  • 24
    • 0027985567 scopus 로고
    • Inhibitors in hemophilia patients: Current status and management
    • Aledort L. Inhibitors in hemophilia patients: current status and management. Am J Hemat 1994; 47: 208-217.
    • (1994) Am J Hemat , vol.47 , pp. 208-217
    • Aledort, L.1
  • 25
    • 0023933922 scopus 로고
    • Induction of immune tolerance in patients with hemophilia and antibodies to factor VIII by combined treatment with intravenous IgG, cyclophosphamide, and factor VIII
    • Nilsson IM, Berntorp E, Zettervall O. Induction of immune tolerance in patients with hemophilia and antibodies to factor VIII by combined treatment with intravenous IgG, cyclophosphamide, and factor VIII. New Engl J Med 1988; 318: 947-950.
    • (1988) New Engl J Med , vol.318 , pp. 947-950
    • Nilsson, I.M.1    Berntorp, E.2    Zettervall, O.3
  • 26
    • 0028896224 scopus 로고
    • Development of a bovine adenovirus type 3-based expression vector
    • Mittal SK, Prevec L, Graham FL, Babiuk LA. Development of a bovine adenovirus type 3-based expression vector. J Gen Virol 1995; 76: 93-102.
    • (1995) J Gen Virol , vol.76 , pp. 93-102
    • Mittal, S.K.1    Prevec, L.2    Graham, F.L.3    Babiuk, L.A.4
  • 28
    • 0014329310 scopus 로고
    • The polypeptides of adenovirus I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12
    • Maizel JV, White DO, Scharff MD. The polypeptides of adenovirus I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology 1968; 36: 115-125.
    • (1968) Virology , vol.36 , pp. 115-125
    • Maizel, J.V.1    White, D.O.2    Scharff, M.D.3
  • 29
    • 0030069229 scopus 로고    scopus 로고
    • High level tissue-specific expression of functional human factor VIII in mice
    • Connelly S, Gardner JM, McClelland A, Kaleko M. High level tissue-specific expression of functional human factor VIII in mice Hum Gene Ther 1996; 7: 183-195.
    • (1996) Hum Gene Ther , vol.7 , pp. 183-195
    • Connelly, S.1    Gardner, J.M.2    McClelland, A.3    Kaleko, M.4
  • 30
    • 0025063533 scopus 로고
    • Characterization of recombinant human factor IX expressed in transgenic mice and in derived transimmortalized hepatic cell lines
    • Jallat S et al. Characterization of recombinant human factor IX expressed in transgenic mice and in derived transimmortalized hepatic cell lines. EMBO J 1990; 9: 3295-3301.
    • (1990) EMBO J , vol.9 , pp. 3295-3301
    • Jallat, S.1
  • 31
    • 0028991820 scopus 로고
    • In vivo gene delivery and expression of physiological levels of functional human factor VIII in mice
    • Connelly S et al. In vivo gene delivery and expression of physiological levels of functional human factor VIII in mice. Hum Gene Ther 1995; 6: 185-193.
    • (1995) Hum Gene Ther , vol.6 , pp. 185-193
    • Connelly, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.