-
1
-
-
0034012647
-
Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates
-
Astriab-Fisher A, Sergueev DS, Fisher M, Shaw BR, Juliano RL (2000) Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochem Pharmacol 60:83-90
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 83-90
-
-
Astriab-Fisher, A.1
Sergueev, D.S.2
Fisher, M.3
Shaw, B.R.4
Juliano, R.L.5
-
2
-
-
0034857627
-
TAT-mediated protein transduction into mammalian cells
-
Becker-Hapak M, McAllister SS, Dowdy SF (2001) TAT-mediated protein transduction into mammalian cells. Methods 24:247-256
-
(2001)
Methods
, vol.24
, pp. 247-256
-
-
Becker-Hapak, M.1
McAllister, S.S.2
Dowdy, S.F.3
-
3
-
-
0033104906
-
Proteoglycan involvement in polyamine uptake
-
Belting M, Persson S, Fransson LA (1999) Proteoglycan involvement in polyamine uptake. Biochem J 338:317-323
-
(1999)
Biochem J
, vol.338
, pp. 317-323
-
-
Belting, M.1
Persson, S.2
Fransson, L.A.3
-
4
-
-
0033790710
-
The transgeneticist's toolbox: Novel methods for the targeted modification of eukaryotic genomes
-
Bode J, Schlake T, Iber M, Schubeler D, Seibler J, Snezhkov E, Nikolaev L (2000) The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes. Biol Chem 381:801-813
-
(2000)
Biol Chem
, vol.381
, pp. 801-813
-
-
Bode, J.1
Schlake, T.2
Iber, M.3
Schubeler, D.4
Seibler, J.5
Snezhkov, E.6
Nikolaev, L.7
-
5
-
-
0033811166
-
Cellular uptake and spread of the cell-permeable peptide penetratin in adult rat brain
-
Bolton SJ, Jones DN, Darker JG, Eggleston DS, Hunter AJ, Walsh FS (2000) Cellular uptake and spread of the cell-permeable peptide penetratin in adult rat brain. Eur J Neurosci 12:2847-2855
-
(2000)
Eur J Neurosci
, vol.12
, pp. 2847-2855
-
-
Bolton, S.J.1
Jones, D.N.2
Darker, J.G.3
Eggleston, D.S.4
Hunter, A.J.5
Walsh, F.S.6
-
6
-
-
0346503889
-
Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice
-
Branda CS, Dymecki SM (2004) Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev Cell 6:7-28
-
(2004)
Dev Cell
, vol.6
, pp. 7-28
-
-
Branda, C.S.1
Dymecki, S.M.2
-
7
-
-
13844256698
-
Tat peptide-mediated cellular delivery: Back to basics
-
Brooks H, Lebleu B, Vives E (2005) Tat peptide-mediated cellular delivery: back to basics. Adv Drug Deliv Rev 57:559-577
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 559-577
-
-
Brooks, H.1
Lebleu, B.2
Vives, E.3
-
8
-
-
21444454735
-
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration
-
Buch T, Heppner FL, Tertilt C, Heinen TJ, Kremer M, Wunderlich FT, Jung S, Waisman A (2005) A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods 2:419-426
-
(2005)
Nat Methods
, vol.2
, pp. 419-426
-
-
Buch, T.1
Heppner, F.L.2
Tertilt, C.3
Heinen, T.J.4
Kremer, M.5
Wunderlich, F.T.6
Jung, S.7
Waisman, A.8
-
9
-
-
0034992138
-
Intracellular delivery of a Tat-eGFP fusion protein into muscle cells
-
Caron NJ, Torrente Y, Camirand G, Bujold M, Chapdelaine P, Leriche K, Bresolin N, Tremblay JP (2001) Intracellular delivery of a Tat-eGFP fusion protein into muscle cells. Mol Ther 3:310-318
-
(2001)
Mol Ther
, vol.3
, pp. 310-318
-
-
Caron, N.J.1
Torrente, Y.2
Camirand, G.3
Bujold, M.4
Chapdelaine, P.5
Leriche, K.6
Bresolin, N.7
Tremblay, J.P.8
-
10
-
-
2442670068
-
Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins
-
Caron NJ, Quenneville SP,Tremblay JP (2004) Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins. Biochem Biophys Res Commun 319:12-20
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 12-20
-
-
Caron, N.J.1
Quenneville, S.P.2
Tremblay, J.P.3
-
11
-
-
0141816702
-
Anovel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival
-
Cohen-SaidonC,NechushtanH,Kahlon S, Livni N,Nissim A, Razin E (2003) Anovel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival. Blood 102:2506-2512
-
(2003)
Blood
, vol.102
, pp. 2506-2512
-
-
Cohen-Saidon, C.1
Nechushtan, H.2
Kahlon, S.3
Livni, N.4
Nissim, A.5
Razin, E.6
-
12
-
-
0037422066
-
Regulated portals of entry into the cell
-
Conner SD, Schmid SL (2003) Regulated portals of entry into the cell. Nature 422:37-44
-
(2003)
Nature
, vol.422
, pp. 37-44
-
-
Conner, S.D.1
Schmid, S.L.2
-
13
-
-
0041816277
-
Antennapedia and HIV transactivator of transcription (TAT) protein transduction domains promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans
-
Console S, Marty C, Garcia-Echeverria C, Schwendener R, Ballmer-Hofer K (2003) Antennapedia and HIV transactivator of transcription (TAT) protein transduction domains promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans. J Biol Chem 278:35109-35114
-
(2003)
J Biol Chem
, vol.278
, pp. 35109-35114
-
-
Console, S.1
Marty, C.2
Garcia-Echeverria, C.3
Schwendener, R.4
Ballmer-Hofer, K.5
-
14
-
-
0032481124
-
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible formof Cre recombinase
-
Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP (1998) Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible formof Cre recombinase. Curr Biol 8:1323-1326
-
(1998)
Curr Biol
, vol.8
, pp. 1323-1326
-
-
Danielian, P.S.1
Muccino, D.2
Rowitch, D.H.3
Michael, S.K.4
McMahon, A.P.5
-
15
-
-
19544389992
-
An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability
-
Demuth I, Frappart PO, Hildebrand G, Melchers A, Lobitz S, Stockl L, Varon R, Herceg Z, Sperling K, Wang ZQ, Digweed M (2004) An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability. Hum Mol Genet 13:2385-2397
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2385-2397
-
-
Demuth, I.1
Frappart, P.O.2
Hildebrand, G.3
Melchers, A.4
Lobitz, S.5
Stockl, L.6
Varon, R.7
Herceg, Z.8
Sperling, K.9
Wang, Z.Q.10
Digweed, M.11
-
16
-
-
0028239908
-
The third helix of the Antennapedia homeodomain translocates through biological membranes
-
Derossi D, Joliot AH, Chassaing G, Prochiantz A (1994) The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem 269:10444-10450
-
(1994)
J Biol Chem
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.H.2
Chassaing, G.3
Prochiantz, A.4
-
17
-
-
0029982569
-
Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
-
Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, Prochiantz A (1996) Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J Biol Chem 271:18188-18193
-
(1996)
J Biol Chem
, vol.271
, pp. 18188-18193
-
-
Derossi, D.1
Calvet, S.2
Trembleau, A.3
Brunissen, A.4
Chassaing, G.5
Prochiantz, A.6
-
18
-
-
0031984072
-
Trojan peptides: The penetratin system for intracellular delivery
-
Derossi D, Chassaing G, Prochiantz A (1998) Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol 8:84-87
-
(1998)
Trends Cell Biol
, vol.8
, pp. 84-87
-
-
Derossi, D.1
Chassaing, G.2
Prochiantz, A.3
-
19
-
-
5644276383
-
Delivery of bioactive molecules into the cell: The Trojan horse approach
-
Dietz GP, Bahr M (2004) Delivery of bioactive molecules into the cell: the Trojan horse approach. Mol Cell Neurosci 27:85-131
-
(2004)
Mol Cell Neurosci
, vol.27
, pp. 85-131
-
-
Dietz, G.P.1
Bahr, M.2
-
20
-
-
0034687854
-
Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation
-
DostmannWR, TaylorMS, Nickl CK, Brayden JE, Frank R, TeggeWJ (2000) Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation. Proc Natl Acad Sci U S A 97:14772-14777
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14772-14777
-
-
Dostmann, W.R.1
Taylor, M.S.2
Nickl, C.K.3
Brayden, J.E.4
Frank, R.5
Tegge, W.J.6
-
21
-
-
0031471203
-
Intercellular trafficking and protein delivery by a herpesvirus structural protein
-
Elliott G, O'Hare P (1997) Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 88:223-233
-
(1997)
Cell
, vol.88
, pp. 223-233
-
-
Elliott, G.1
O'hare, P.2
-
22
-
-
0030924438
-
Hypophosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb
-
Ezhevsky SA, Nagahara H, Vocero-Akbani AM, Gius DR,Wei MC, Dowdy SF (1997) Hypophosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb. Proc Natl Acad Sci U S A 94:10699-10704
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10699-10704
-
-
Ezhevsky, S.A.1
Nagahara, H.2
Vocero-Akbani, A.M.3
Gius, D.R.4
Wei, M.C.5
Dowdy, S.F.6
-
23
-
-
0035836609
-
Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
-
Falnes PO, Wesche J, Olsnes S (2001) Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment. Biochemistry 40:4349-4358
-
(2001)
Biochemistry
, vol.40
, pp. 4349-4358
-
-
Falnes, P.O.1
Wesche, J.2
Olsnes, S.3
-
24
-
-
0031786954
-
Intercellular trafficking of VP22-GFP fusion proteins is not observed in cultured mammalian cells
-
Fang B, Xu B, Koch P, Roth JA (1998) Intercellular trafficking of VP22-GFP fusion proteins is not observed in cultured mammalian cells. Gene Ther 5:1420-1424
-
(1998)
Gene Ther
, vol.5
, pp. 1420-1424
-
-
Fang, B.1
Xu, B.2
Koch, P.3
Roth, J.A.4
-
25
-
-
0028054797
-
Tat-mediated delivery of heterologous proteins into cells
-
Fawell S, Seery J, Daikh Y, Moore C, Chen LL, Pepinsky B, Barsoum J (1994) Tat-mediated delivery of heterologous proteins into cells. Proc Natl Acad Sci U S A 91:664-668
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 664-668
-
-
Fawell, S.1
Seery, J.2
Daikh, Y.3
Moore, C.4
Chen, L.L.5
Pepinsky, B.6
Barsoum, J.7
-
26
-
-
0029767838
-
Ligand-activated site-specific recombination in mice
-
Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, Chambon P (1996) Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci U S A 93:10887-10890
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10887-10890
-
-
Feil, R.1
Brocard, J.2
Mascrez, B.3
Lemeur, M.4
Metzger, D.5
Chambon, P.6
-
27
-
-
0042355293
-
Caveolaemediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time
-
Ferrari A, Pellegrini V, Arcangeli C, Fittipaldi A, Giacca M, Beltram F (2003) Caveolaemediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time. Mol Ther 8:284-294
-
(2003)
Mol Ther
, vol.8
, pp. 284-294
-
-
Ferrari, A.1
Pellegrini, V.2
Arcangeli, C.3
Fittipaldi, A.4
Giacca, M.5
Beltram, F.6
-
28
-
-
0141446039
-
Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins
-
Fittipaldi A, Ferrari A, Zoppe M, Arcangeli C, Pellegrini V, Beltram F, Giacca M (2003) Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins. J Biol Chem 278:34141-34149
-
(2003)
J Biol Chem
, vol.278
, pp. 34141-34149
-
-
Fittipaldi, A.1
Ferrari, A.2
Zoppe, M.3
Arcangeli, C.4
Pellegrini, V.5
Beltram, F.6
Giacca, M.7
-
29
-
-
0024262589
-
Cellular uptake of the tat protein from human immunodeficiency virus
-
Frankel AD, Pabo CO (1988) Cellular uptake of the tat protein from human immunodeficiency virus. Cell 55:1189-1193
-
(1988)
Cell
, vol.55
, pp. 1189-1193
-
-
Frankel, A.D.1
Pabo, C.O.2
-
30
-
-
0034543064
-
Inducible and irreversible control of gene expression using a single transgene
-
Fuhrmann-BenzakeinE,Garcia-Gabay I,PepperMS,VassalliJD,HerreraPL (2000) Inducible and irreversible control of gene expression using a single transgene. Nucleic Acids Res 28:e99
-
(2000)
Nucleic Acids Res
, vol.28
-
-
Fuhrmann-Benzakein, E.1
Garcia-Gabay, I.2
Pepper, M.S.3
Vassalli, J.D.4
Herrera, P.L.5
-
31
-
-
21844474526
-
The interaction of the cell-penetrating peptide penetratin with heparin, heparansulfates and phospholipid vesicles investigated by ESR spectroscopy
-
Ghibaudi E, Boscolo B, Inserra G, Laurenti E, Traversa S, Barbero L, Ferrari RP (2005) The interaction of the cell-penetrating peptide penetratin with heparin, heparansulfates and phospholipid vesicles investigated by ESR spectroscopy. J Pept Sci 11:401-409
-
(2005)
J Pept Sci
, vol.11
, pp. 401-409
-
-
Ghibaudi, E.1
Boscolo, B.2
Inserra, G.3
Laurenti, E.4
Traversa, S.5
Barbero, L.6
Ferrari, R.P.7
-
32
-
-
0033137321
-
Transduced p16INK4a peptides inhibit hypophosphorylation of the retinoblastoma protein and cell cycle progression prior to activation of Cdk2 complexes in late G1
-
GiusDR, Ezhevsky SA,Becker-Hapak M,Nagahara H,WeiMC,Dowdy SF (1999) Transduced p16INK4a peptides inhibit hypophosphorylation of the retinoblastoma protein and cell cycle progression prior to activation of Cdk2 complexes in late G1. Cancer Res 59:2577-2580
-
(1999)
Cancer Res
, vol.59
, pp. 2577-2580
-
-
Gius, D.R.1
Ezhevsky, S.A.2
Becker-Hapak, M.3
Nagahara, H.4
Wei, M.C.5
Dowdy, S.F.6
-
33
-
-
19644377571
-
Transient upregulation of GRP and its receptor critically regulate colon cancer cell motility during remodeling
-
Glover S, Nathaniel R, Shakir L, Perrault C, Anderson RK, Tran-Son-Tay R, Benya RV (2005) Transient upregulation of GRP and its receptor critically regulate colon cancer cell motility during remodeling. Am J Physiol Gastrointest Liver Physiol 288:G1274-G1282
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
-
-
Glover, S.1
Nathaniel, R.2
Shakir, L.3
Perrault, C.4
Anderson, R.K.5
Tran-Son-Tay, R.6
Benya, R.V.7
-
34
-
-
0038061635
-
Protein transduction domains: Are they delivering?
-
Green I, Christison R, Voyce CJ, Bundell KR, Lindsay MA (2003) Protein transduction domains: are they delivering? Trends Pharmacol Sci 24:213-215
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 213-215
-
-
Green, I.1
Christison, R.2
Voyce, C.J.3
Bundell, K.R.4
Lindsay, M.A.5
-
35
-
-
0024209811
-
Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein
-
Green M, Loewenstein PM (1988) Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein. Cell 55:1179-1188
-
(1988)
Cell
, vol.55
, pp. 1179-1188
-
-
Green, M.1
Loewenstein, P.M.2
-
36
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu H,Marth JD, Orban PC,Mossmann H, Rajewsky K (1994) Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 265:103-106
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
37
-
-
1442327629
-
TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells
-
Guelen L, Paterson H, Gaken J, Meyers M, Farzaneh F, Tavassoli M (2004) TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells. Oncogene 23:1153-1165
-
(2004)
Oncogene
, vol.23
, pp. 1153-1165
-
-
Guelen, L.1
Paterson, H.2
Gaken, J.3
Meyers, M.4
Farzaneh, F.5
Tavassoli, M.6
-
38
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M, McCormack MP, Wulffraat N, Leboulch P, Lim A, Osborne CS, Pawliuk R, Morillon E, Sorensen R, Forster A, Fraser P, Cohen JI, de Saint Basile G, Alexander I, Wintergerst U, Frebourg T, Aurias A, Stoppa-Lyonnet D, Romana S, Radford-Weiss I, Gross F, Valensi F, Delabesse E, Macintyre E, Sigaux F, Soulier J, Leiva LE, WisslerM, Prinz C, Rabbitts TH, Le Deist F, Fischer A, Cavazzana-Calvo M (2003) LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302:415-419
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
McCormack, M.P.4
Wulffraat, N.5
Leboulch, P.6
Lim, A.7
Osborne, C.S.8
Pawliuk, R.9
Morillon, E.10
Sorensen, R.11
Forster, A.12
Fraser, P.13
Cohen, J.I.14
De Saint Basile, G.15
Alexander, I.16
Wintergerst, U.17
Frebourg, T.18
Aurias, A.19
Stoppa-Lyonnet, D.20
Romana, S.21
Radford-Weiss, I.22
Gross, F.23
Valensi, F.24
Delabesse, E.25
Macintyre, E.26
Sigaux, F.27
Soulier, J.28
Leiva, L.E.29
Wissler, M.30
Prinz, C.31
Rabbitts, T.H.32
Le Deist, F.33
Fischer, A.34
Cavazzana-Calvo, M.35
more..
-
39
-
-
22544473939
-
VP22 does not significantly enhance enzyme prodrug cancer gene therapy as a part of a VP22-HSVTk-GFP triple fusion construct
-
Hakkarainen T, Wahlfors T, Merilainen O, Loimas S, Hemminki A, Wahlfors J (2005) VP22 does not significantly enhance enzyme prodrug cancer gene therapy as a part of a VP22-HSVTk-GFP triple fusion construct. J Gene Med 7:898-907
-
(2005)
J Gene Med
, vol.7
, pp. 898-907
-
-
Hakkarainen, T.1
Wahlfors, T.2
Merilainen, O.3
Loimas, S.4
Hemminki, A.5
Wahlfors, J.6
-
40
-
-
0035980813
-
Efficient intracellular delivery of an exogenous protein GFP with genetically fused basic oligopeptides
-
Han K, JeonMJ, Kim SH, Ki D, Bahn JH, Lee KS, Park J, Choi SY (2001) Efficient intracellular delivery of an exogenous protein GFP with genetically fused basic oligopeptides. Mol Cells 12:267-271
-
(2001)
Mol Cells
, vol.12
, pp. 267-271
-
-
Han, K.1
Jeon, M.J.2
Kim, S.H.3
Ki, D.4
Bahn, J.H.5
Lee, K.S.6
Park, J.7
Choi, S.Y.8
-
41
-
-
84884553983
-
Stage specific conditional mutagenesis inmouseembryonic stemcell-derived neural cells andpost-mitotic neurons by direct delivery of biologically active Cre recombinase
-
2006 Sep 7; [Epub ahead of print]
-
Haupt S, Edenhofer F, Peitz M, Leinhaas A, Brustle O (2006) Stage specific conditional mutagenesis inmouseembryonic stemcell-derived neural cells andpost-mitotic neurons by direct delivery of biologically active Cre recombinase. Stem Cells. 2006 Sep 7; [Epub ahead of print]
-
(2006)
Stem Cells
-
-
Haupt, S.1
Edenhofer, F.2
Peitz, M.3
Leinhaas, A.4
Brustle, O.5
-
42
-
-
17044398110
-
Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: Potential advantages over antibodies expressed within the intracellular environment (Intrabody)
-
Heng BC, Cao T (2005) Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: potential advantages over antibodies expressed within the intracellular environment (Intrabody) . Med Hypotheses 64:1105-1108
-
(2005)
Med Hypotheses
, vol.64
, pp. 1105-1108
-
-
Heng, B.C.1
Cao, T.2
-
43
-
-
0035863391
-
Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo
-
Ho A, Schwarze SR,Mermelstein SJ,Waksman G, Dowdy SF (2001) Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res 61:474-477
-
(2001)
Cancer Res
, vol.61
, pp. 474-477
-
-
Ho, A.1
Schwarze, S.R.2
Mermelstein, S.J.3
Waksman, G.4
Dowdy, S.F.5
-
44
-
-
1842394365
-
P1 site-specific recombination: Nucleotide sequence of the recombining sites
-
Hoess RH, Ziese M, Sternberg N (1982) P1 site-specific recombination: nucleotide sequence of the recombining sites. Proc Natl Acad Sci U S A 79:3398-3402
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 3398-3402
-
-
Hoess, R.H.1
Ziese, M.2
Sternberg, N.3
-
45
-
-
0037385313
-
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
-
Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH (2003) Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol 4:321-329
-
(2003)
Nat Immunol
, vol.4
, pp. 321-329
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Vallabhajosyula, P.3
Otipoby, K.L.4
Rajewsky, K.5
Glimcher, L.H.6
-
46
-
-
0034794191
-
Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase
-
JoD,Nashabi A,Doxsee C, LinQ,UnutmazD, Chen J, RuleyHE (2001) Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nat Biotechnol 19:929-933
-
(2001)
Nat Biotechnol
, vol.19
, pp. 929-933
-
-
Jo, D.1
Nashabi, A.2
Doxsee, C.3
Lin, Q.4
Unutmaz, D.5
Chen, J.6
Ruley, H.E.7
-
47
-
-
0036274381
-
Induced DNA recombination by Cre recombinase protein transduction
-
Joshi SK, Hashimoto K, Koni PA (2002) Induced DNA recombination by Cre recombinase protein transduction. Genesis 33:48-54
-
(2002)
Genesis
, vol.33
, pp. 48-54
-
-
Joshi, S.K.1
Hashimoto, K.2
Koni, P.A.3
-
48
-
-
0142155259
-
Biological applications of protein transduction technology
-
Kabouridis PS (2003) Biological applications of protein transduction technology. Trends Biotechnol 21:498-503
-
(2003)
Trends Biotechnol
, vol.21
, pp. 498-503
-
-
Kabouridis, P.S.1
-
49
-
-
11844268027
-
Cationic TAT peptide transduction domain enters cells by macropinocytosis
-
Kaplan IM, Wadia JS, Dowdy SF (2005) Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Release 102:247-253
-
(2005)
J Control Release
, vol.102
, pp. 247-253
-
-
Kaplan, I.M.1
Wadia, J.S.2
Dowdy, S.F.3
-
50
-
-
0033534701
-
Inducible sitespecific recombination in the brain
-
Kellendonk C, Tronche F, Casanova E, Anlag K, Opherk C, Schutz G (1999) Inducible sitespecific recombination in the brain. J Mol Biol 285:175-182
-
(1999)
J Mol Biol
, vol.285
, pp. 175-182
-
-
Kellendonk, C.1
Tronche, F.2
Casanova, E.3
Anlag, K.4
Opherk, C.5
Schutz, G.6
-
51
-
-
0347382317
-
Anti-neovascular therapy by liposomal drug targeted tomembrane type-1 matrix metalloproteinase
-
Kondo M, Asai T, Katanasaka Y, Sadzuka Y, Tsukada H, Ogino K, Taki T, Baba K, Oku N (2004) Anti-neovascular therapy by liposomal drug targeted tomembrane type-1 matrix metalloproteinase. Int J Cancer 108:301-306
-
(2004)
Int J Cancer
, vol.108
, pp. 301-306
-
-
Kondo, M.1
Asai, T.2
Katanasaka, Y.3
Sadzuka, Y.4
Tsukada, H.5
Ogino, K.6
Taki, T.7
Baba, K.8
Oku, N.9
-
52
-
-
13444281917
-
Nibrin functions in Ig class-switch recombination
-
Kracker S, Bergmann Y, Demuth I, Frappart PO, Hildebrand G, Christine R, Wang ZQ, Sperling K, Digweed M, Radbruch A (2005) Nibrin functions in Ig class-switch recombination. Proc Natl Acad Sci U S A 102:1584-1589
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1584-1589
-
-
Kracker, S.1
Bergmann, Y.2
Demuth, I.3
Frappart, P.O.4
Hildebrand, G.5
Christine, R.6
Wang, Z.Q.7
Sperling, K.8
Digweed, M.9
Radbruch, A.10
-
53
-
-
0344413639
-
Vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
-
Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G (2003) In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med 9:1428-1432
-
(2003)
Nat Med
, vol.9
, pp. 1428-1432
-
-
Krosl, J.1
Austin, P.2
Beslu, N.3
Kroon, E.4
Humphries, R.K.5
Sauvageau, G.6
-
55
-
-
0034919755
-
Tetracyclines inhibit activated B cell function
-
Kuzin II, Snyder JE, Ugine GD, Wu D, Lee S, Bushnell T Jr, Insel RA, Young FM, Bottaro A (2001) Tetracyclines inhibit activated B cell function. Int Immunol 13:921-931
-
(2001)
Int Immunol
, vol.13
, pp. 921-931
-
-
Kuzin, I.I.1
Snyder, J.E.2
Ugine, G.D.3
Wu, D.4
Lee, S.5
Bushnell Jr., T.6
Insel, R.A.7
Young, F.M.8
Bottaro, A.9
-
56
-
-
20844449780
-
Cellular manipulation of human embryonic stem cells by TAT-PDX1 protein transduction
-
Kwon YD, Oh SK, Kim HS, Ku SY, Kim SH, Choi YM,Moon SY (2005) Cellular manipulation of human embryonic stem cells by TAT-PDX1 protein transduction. Mol Ther 12:28-32
-
(2005)
Mol Ther
, vol.12
, pp. 28-32
-
-
Kwon, Y.D.1
Oh, S.K.2
Kim, H.S.3
Ku, S.Y.4
Kim, S.H.5
Choi, Y.M.6
Moon, S.Y.7
-
57
-
-
0026638820
-
Targeted oncogene activation by site-specific recombination in transgenic mice
-
LaksoM, Sauer B,Mosinger B Jr, Lee EJ,Manning RW, Yu SH,Mulder KL,WestphalH (1992) Targeted oncogene activation by site-specific recombination in transgenic mice. Proc Natl Acad Sci U S A 89:6232-6236
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 6232-6236
-
-
Lakso, M.1
Sauer, B.2
Mosinger Jr., B.3
Lee, E.J.4
Manning, R.W.5
Yu, S.H.6
Mulder, K.L.7
Westphal, H.8
-
58
-
-
0036846565
-
Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity
-
Leifert JA, Harkins S, Whitton JL (2002) Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity. Gene Ther 9:1422-1428
-
(2002)
Gene Ther
, vol.9
, pp. 1422-1428
-
-
Leifert, J.A.1
Harkins, S.2
Whitton, J.L.3
-
59
-
-
0035491607
-
Conditional control of gene expression in the mouse
-
Lewandoski M (2001) Conditional control of gene expression in the mouse. Nat Rev Genet 2:743-755
-
(2001)
Nat Rev Genet
, vol.2
, pp. 743-755
-
-
Lewandoski, M.1
-
60
-
-
0034006169
-
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
-
Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R (2000) Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol 18:410-414
-
(2000)
Nat Biotechnol
, vol.18
, pp. 410-414
-
-
Lewin, M.1
Carlesso, N.2
Tung, C.H.3
Tang, X.W.4
Cory, D.5
Scadden, D.T.6
Weissleder, R.7
-
61
-
-
0031962665
-
Impairment of T and B cell development by treatment with a type i interferon
-
Lin Q, Dong C, Cooper MD (1998) Impairment of T and B cell development by treatment with a type I interferon. J Exp Med 187:79-87
-
(1998)
J Exp Med
, vol.187
, pp. 79-87
-
-
Lin, Q.1
Dong, C.2
Cooper, M.D.3
-
62
-
-
13244251060
-
Enhanced cell-permeant Cre protein for site-specific recombination in cultured cells
-
Lin Q, Jo D, Gebre-Amlak KD, Ruley HE (2004) Enhanced cell-permeant Cre protein for site-specific recombination in cultured cells. BMC Biotechnol 4:25
-
(2004)
BMC Biotechnol
, vol.4
, pp. 25
-
-
Lin, Q.1
Jo, D.2
Gebre-Amlak, K.D.3
Ruley, H.E.4
-
63
-
-
0029006149
-
Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membranepermeable motif and nuclear localization sequence
-
Lin YZ,Yao SY,VeachRA,TorgersonTR,Hawiger J (1995) Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membranepermeable motif and nuclear localization sequence. J Biol Chem 270:14255-14258
-
(1995)
J Biol Chem
, vol.270
, pp. 14255-14258
-
-
Lin, Y.Z.1
Yao, S.Y.2
Veach, R.A.3
Torgerson, T.R.4
Hawiger, J.5
-
64
-
-
0034529953
-
Uptake ofHIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands
-
Liu Y, Jones M, Hingtgen CM, Bu G, Laribee N, Tanzi RE, Moir RD, Nath A, He JJ (2000) Uptake ofHIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands. Nat Med 6:1380-1387
-
(2000)
Nat Med
, vol.6
, pp. 1380-1387
-
-
Liu, Y.1
Jones, M.2
Hingtgen, C.M.3
Bu, G.4
Laribee, N.5
Tanzi, R.E.6
Moir, R.D.7
Nath, A.8
He, J.J.9
-
65
-
-
0029043630
-
Ligand-regulated site-specific recombination
-
Logie C, Stewart AF (1995) Ligand-regulated site-specific recombination. Proc Natl Acad Sci U S A 92:5940-5944
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5940-5944
-
-
Logie, C.1
Stewart, A.F.2
-
66
-
-
0035979247
-
Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells
-
Loonstra A, Vooijs M, Beverloo HB, Allak BA, van Drunen E, Kanaar R, Berns A, Jonkers J (2001) Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells. Proc Natl Acad Sci U S A 98:9209-9214
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9209-9214
-
-
Loonstra, A.1
Vooijs, M.2
Beverloo, H.B.3
Allak, B.A.4
Van Drunen, E.5
Kanaar, R.6
Berns, A.7
Jonkers, J.8
-
67
-
-
0034910022
-
Is VP22 nuclear homing an artifact?
-
Lundberg M, Johansson M (2001) Is VP22 nuclear homing an artifact? Nat Biotechnol 19:713-714
-
(2001)
Nat Biotechnol
, vol.19
, pp. 713-714
-
-
Lundberg, M.1
Johansson, M.2
-
68
-
-
0027310927
-
Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function
-
Madore SJ, Cullen BR (1993) Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function. J Virol 67:3703-3711
-
(1993)
J Virol
, vol.67
, pp. 3703-3711
-
-
Madore, S.J.1
Cullen, B.R.2
-
69
-
-
0037119348
-
Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate
-
Mai JC, Shen H,Watkins SC, Cheng T, Robbins PD (2002) Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate. J Biol Chem 277:30208-30218
-
(2002)
J Biol Chem
, vol.277
, pp. 30208-30218
-
-
Mai, J.C.1
Shen, H.2
Watkins, S.C.3
Cheng, T.4
Robbins, P.D.5
-
70
-
-
0035882281
-
A high-efficiency protein transduction system demonstrating the role of PKA in long-lasting long-term potentiation
-
Matsushita M, Tomizawa K,Moriwaki A, Li ST, Terada H,Matsui H (2001) A high-efficiency protein transduction system demonstrating the role of PKA in long-lasting long-term potentiation. J Neurosci 21:6000-6007
-
(2001)
J Neurosci
, vol.21
, pp. 6000-6007
-
-
Matsushita, M.1
Tomizawa, K.2
Moriwaki, A.3
Li, S.T.4
Terada, H.5
Matsui, H.6
-
71
-
-
4143109220
-
Photo-acceleration of protein release from endosome in the protein transduction system
-
Matsushita M, Noguchi H, Lu YF, Tomizawa K, Michiue H, Li ST, Hirose K, Bonner-Weir S, Matsui H (2004) Photo-acceleration of protein release from endosome in the protein transduction system. FEBS Lett 572:221-226
-
(2004)
FEBS Lett
, vol.572
, pp. 221-226
-
-
Matsushita, M.1
Noguchi, H.2
Lu, Y.F.3
Tomizawa, K.4
Michiue, H.5
Li, S.T.6
Hirose, K.7
Bonner-Weir, S.8
Matsui, H.9
-
72
-
-
0022803360
-
Identificationof the crossover siteduringFLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle
-
McLeodM,Craft S,Broach JR (1986) Identificationof the crossover siteduringFLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle. Mol Cell Biol 6:3357-3367
-
(1986)
Mol Cell Biol
, vol.6
, pp. 3357-3367
-
-
McLeod, M.1
Craft, S.2
Broach, J.R.3
-
73
-
-
0029164598
-
Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase
-
Metzger D, Clifford J, Chiba H, Chambon P (1995) Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. ProcNatl Acad Sci U S A 92:6991-6995
-
(1995)
ProcNatl Acad Sci U S A
, vol.92
, pp. 6991-6995
-
-
Metzger, D.1
Clifford, J.2
Chiba, H.3
Chambon, P.4
-
74
-
-
0035970515
-
Inducible gene targeting in postnatalmyocardium by cardiac-specific expression of a hormone-activated Cre fusion protein
-
Minamino T, Gaussin V, DeMayo FJ, Schneider MD (2001) Inducible gene targeting in postnatalmyocardium by cardiac-specific expression of a hormone-activated Cre fusion protein. Circ Res 88:587-592
-
(2001)
Circ Res
, vol.88
, pp. 587-592
-
-
Minamino, T.1
Gaussin, V.2
Demayo, F.J.3
Schneider, M.D.4
-
75
-
-
28444470467
-
Suppression of gene expression by a cell-permeable Tet repressor
-
Mortlock A, Low W, Crisanti A (2003) Suppression of gene expression by a cell-permeable Tet repressor. Nucleic Acids Res 31:e152
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Mortlock, A.1
Low, W.2
Crisanti, A.3
-
76
-
-
3242721268
-
MTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
-
Murakami M, Ichisaka T,Maeda M, Oshiro N, Hara K, Edenhofer F, Kiyama H, Yonezawa K, Yamanaka S (2004) mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol 24:6710-6718
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6710-6718
-
-
Murakami, M.1
Ichisaka, T.2
Maeda, M.3
Oshiro, N.4
Hara, K.5
Edenhofer, F.6
Kiyama, H.7
Yonezawa, K.8
Yamanaka, S.9
-
77
-
-
0031759170
-
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
-
Nagahara H, Vocero-Akbani AM, Snyder EL, Ho A, Latham DG, Lissy NA, Becker-HapakM, Ezhevsky SA, Dowdy SF (1998) Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat Med 4:1449-1452
-
(1998)
Nat Med
, vol.4
, pp. 1449-1452
-
-
Nagahara, H.1
Vocero-Akbani, A.M.2
Snyder, E.L.3
Ho, A.4
Latham, D.G.5
Lissy, N.A.6
Becker-Hapak, M.7
Ezhevsky, S.A.8
Dowdy, S.F.9
-
78
-
-
0034059140
-
Cre recombinase: The universal reagent for genome tailoring
-
Nagy A (2000) Cre recombinase: the universal reagent for genome tailoring. Genesis 26:99-109
-
(2000)
Genesis
, vol.26
, pp. 99-109
-
-
Nagy, A.1
-
79
-
-
10344221003
-
Cellular uptake of arginine-rich peptides: Roles for macropinocytosis and actin rearrangement
-
Nakase I, Niwa M, Takeuchi T, Sonomura K, Kawabata N, Koike Y, Takehashi M, Tanaka S, Ueda K, Simpson JC, JonesAT, Sugiura Y, Futaki S (2004) Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement. Mol Ther 10:1011-1022
-
(2004)
Mol Ther
, vol.10
, pp. 1011-1022
-
-
Nakase, I.1
Niwa, M.2
Takeuchi, T.3
Sonomura, K.4
Kawabata, N.5
Koike, Y.6
Takehashi, M.7
Tanaka, S.8
Ueda, K.9
Simpson, J.C.10
Jones, A.T.11
Sugiura, Y.12
Futaki, S.13
-
80
-
-
0028827795
-
Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo
-
Narita M, Bu G, Olins GM,Higuchi DA,Herz J, Broze GJ Jr, Schwartz AL (1995) Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo. J Biol Chem 270:24800-24804
-
(1995)
J Biol Chem
, vol.270
, pp. 24800-24804
-
-
Narita, M.1
Bu, G.2
Olins, G.M.3
Higuchi, D.A.4
Herz, J.5
Broze Jr., G.J.6
Schwartz, A.L.7
-
81
-
-
33744527608
-
Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase
-
Jun
-
Nolden L, Edenhofer F, Haupt S, Koch P,Wunderlich FT, Siemen H, Brustle O. Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase. Nat Methods. 2006 Jun;3 (6) 461-7
-
(2006)
Nat Methods
, vol.3
, Issue.6
, pp. 461-467
-
-
Nolden, L.1
Edenhofer, F.2
Haupt, S.3
Koch, P.4
Wunderlich, F.T.5
Siemen, H.6
Brustle, O.7
-
82
-
-
2142746976
-
Unidirectional Cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71
-
Oberdoerffer P, Otipoby KL,Maruyama M, Rajewsky K (2003) Unidirectional Cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71. Nucleic Acids Res 31:e140
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Oberdoerffer, P.1
Otipoby, K.L.2
Maruyama, M.3
Rajewsky, K.4
-
83
-
-
0026764280
-
Tissue-and site-specific DNA recombination in transgenic mice
-
Orban PC, Chui D, Marth JD (1992) Tissue-and site-specific DNA recombination in transgenic mice. Proc Natl Acad Sci U S A 89:6861-6865
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 6861-6865
-
-
Orban, P.C.1
Chui, D.2
Marth, J.D.3
-
84
-
-
0037007121
-
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes
-
Peitz M, Pfannkuche K, Rajewsky K, Edenhofer F (2002) Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc Natl Acad Sci U S A 99:4489-4494
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 4489-4494
-
-
Peitz, M.1
Pfannkuche, K.2
Rajewsky, K.3
Edenhofer, F.4
-
86
-
-
0034569731
-
Messenger proteins
-
Prochiantz A (2000) [Messenger proteins]. J Soc Biol 194:119-123
-
(2000)
J Soc Biol
, vol.194
, pp. 119-123
-
-
Prochiantz, A.1
-
87
-
-
0029959207
-
Conditional gene targeting
-
Rajewsky K, Gu H, Kuhn R, Betz UA, MullerW, Roes J, Schwenk F (1996) Conditional gene targeting. J Clin Invest 98:600-603
-
(1996)
J Clin Invest
, vol.98
, pp. 600-603
-
-
Rajewsky, K.1
Gu, H.2
Kuhn, R.3
Betz, U.A.4
Muller, W.5
Roes, J.6
Schwenk, F.7
-
88
-
-
0346460957
-
Cell-penetrating peptides
-
Richard JP, Melikov K, Vives E, Ramos C, Verbeure B, Gait MJ, Chernomordik LV, Lebleu B (2003) Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J Biol Chem 278:585-590
-
(2003)
A Reevaluation of the Mechanism of Cellular Uptake. J Biol Chem
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
Ramos, C.4
Verbeure, B.5
Gait, M.J.6
Chernomordik, L.V.7
Lebleu, B.8
-
89
-
-
17644386231
-
Cellularuptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
-
RichardJP,Melikov K,Brooks H,PrevotP,LebleuB, ChernomordikLV (2005) Cellularuptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J Biol Chem 280:15300-15306
-
(2005)
J Biol Chem
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
Melikov, K.2
Brooks, H.3
Prevot, P.4
Lebleu, B.5
Chernomordik, L.V.6
-
90
-
-
0029959746
-
Sustained somatic gene inactivation by viral transfer of Cre recombinase
-
Rohlmann A, Gotthardt M,Willnow TE, Hammer RE, Herz J (1996) Sustained somatic gene inactivation by viral transfer of Cre recombinase. Nat Biotechnol 14:1562-1565
-
(1996)
Nat Biotechnol
, vol.14
, pp. 1562-1565
-
-
Rohlmann, A.1
Gotthardt, M.2
Willnow, T.E.3
Hammer, R.E.4
Herz, J.5
-
91
-
-
0028843052
-
The Flp recombinase of the 2-microns plasmid of Saccharomyces cerevisiae
-
Sadowski PD (1995) The Flp recombinase of the 2-microns plasmid of Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol 51:53-91
-
(1995)
Prog Nucleic Acid Res Mol Biol
, vol.51
, pp. 53-91
-
-
Sadowski, P.D.1
-
92
-
-
2342520028
-
The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis
-
Sandgren S,Wittrup A, Cheng F, JonssonM, Eklund E, Busch S, BeltingM (2004) The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis. J Biol Chem 279:17951-17956
-
(2004)
J Biol Chem
, vol.279
, pp. 17951-17956
-
-
Sandgren, S.1
Wittrup, A.2
Cheng, F.3
Jonsson, M.4
Eklund, E.5
Busch, S.6
Belting, M.7
-
93
-
-
0033520487
-
Vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF (1999) In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285:1569-1572
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
94
-
-
0034237577
-
Protein transduction: Unrestricted delivery into all cells?
-
Schwarze SR, Hruska KA, Dowdy SF (2000) Protein transduction: unrestricted delivery into all cells? Trends Cell Biol 10:290-295
-
(2000)
Trends Cell Biol
, vol.10
, pp. 290-295
-
-
Schwarze, S.R.1
Hruska, K.A.2
Dowdy, S.F.3
-
95
-
-
0030843461
-
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene
-
Shibata H, Toyama K, Shioya H, Ito M, Hirota M, Hasegawa S, Matsumoto H, Takano H, Akiyama T, Toyoshima K, Kanamaru R, Kanegae Y, Saito I,Nakamura Y, Shiba K,Noda T (1997) Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science 278:120-123
-
(1997)
Science
, vol.278
, pp. 120-123
-
-
Shibata, H.1
Toyama, K.2
Shioya, H.3
Ito, M.4
Hirota, M.5
Hasegawa, S.6
Matsumoto, H.7
Takano, H.8
Akiyama, T.9
Toyoshima, K.10
Kanamaru, R.11
Kanegae, Y.12
Saito, I.13
Nakamura, Y.14
Shiba, K.15
Noda, T.16
-
96
-
-
0036159271
-
Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat
-
SilholM, TyagiM, Giacca M, Lebleu B, Vives E (2002) Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat. Eur J Biochem 269:494-501
-
(2002)
Eur J Biochem
, vol.269
, pp. 494-501
-
-
Silhol, M.1
Tyagi, M.2
Giacca, M.3
Lebleu, B.4
Vives, E.5
-
97
-
-
0034888424
-
Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity
-
Silver DP, Livingston DM (2001) Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity. Mol Cell 8:233-243
-
(2001)
Mol Cell
, vol.8
, pp. 233-243
-
-
Silver, D.P.1
Livingston, D.M.2
-
98
-
-
23244431661
-
Parenchymal expression of CD86/B7.2 contributes to hepatitis C virus-related liver injury
-
Sun J, Tumurbaatar B, Jia J, Diao H, Bodola F, Lemon SM, Tang W, Bowen DG, Mc-Caughan GW, Bertolino P, Chan T-S (2005) Parenchymal expression of CD86/B7.2 contributes to hepatitis C virus-related liver injury. J Virol 79:10730-10739
-
(2005)
J Virol
, vol.79
, pp. 10730-10739
-
-
Sun, J.1
Tumurbaatar, B.2
Jia, J.3
Diao, H.4
Bodola, F.5
Lemon, S.M.6
Tang, W.7
Bowen, D.G.8
Mc-Caughan, G.W.9
Bertolino, P.10
Chan, T.-S.11
-
99
-
-
0037169486
-
Possible existence of common internalization mechanisms among arginine-rich peptides
-
SuzukiT, Futaki S,NiwaM,Tanaka S,Ueda K, SugiuraY (2002) Possible existence of common internalization mechanisms among arginine-rich peptides. J Biol Chem 277:2437-2443
-
(2002)
J Biol Chem
, vol.277
, pp. 2437-2443
-
-
Suzuki, T.1
Futaki, S.2
Niwa, M.3
Tanaka, S.4
Ueda, K.5
Sugiura, Y.6
-
100
-
-
0037680428
-
Development of p53 protein transduction therapy using membrane-permeable peptides and the application to oral cancer cells
-
Takenobu T, Tomizawa K, Matsushita M, Li ST, Moriwaki A, Lu YF, Matsui H (2002) Development of p53 protein transduction therapy using membrane-permeable peptides and the application to oral cancer cells. Mol Cancer Ther 1:1043-1049
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1043-1049
-
-
Takenobu, T.1
Tomizawa, K.2
Matsushita, M.3
Li, S.T.4
Moriwaki, A.5
Lu, Y.F.6
Matsui, H.7
-
101
-
-
0035902477
-
TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
-
Torchilin VP, Rammohan R,Weissig V, Levchenko TS (2001) TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors. Proc Natl Acad Sci U S A 98:8786-8791
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8786-8791
-
-
Torchilin, V.P.1
Rammohan, R.2
Weissig, V.3
Levchenko, T.S.4
-
102
-
-
0037428976
-
Arginine containing peptides as delivery vectors
-
Tung CH, Weissleder R (2003) Arginine containing peptides as delivery vectors. Adv Drug Deliv Rev 55:281-294
-
(2003)
Adv Drug Deliv Rev
, vol.55
, pp. 281-294
-
-
Tung, C.H.1
Weissleder, R.2
-
103
-
-
33748648777
-
Cargodependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells
-
Sep;20 (11)
-
Tünnemann G, Martin RM, Haupt S, Patsch C, Edendorfer F, Cardoso MC (2006) Cargodependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells. FASEB J 2006 Sep;20 (11) :1775-84
-
(2006)
FASEB J
, vol.2006
, pp. 1775-1784
-
-
Tünnemann, G.1
Martin, R.M.2
Haupt, S.3
Patsch, C.4
Edendorfer, F.5
Cardoso, M.C.6
-
104
-
-
0035793619
-
Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans
-
Tyagi M, Rusnati M, Presta M, Giacca M (2001) Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans. J Biol Chem 276:3254-3261
-
(2001)
J Biol Chem
, vol.276
, pp. 3254-3261
-
-
Tyagi, M.1
Rusnati, M.2
Presta, M.3
Giacca, M.4
-
105
-
-
20944435721
-
Basal immunoglobulin signaling actively maintains developmental stage in immature B cells
-
Tze LE, Schram BR, Lam KP, Hogquist KA, Hippen KL, Liu J, Shinton SA, Otipoby KL, Rodine PR,Vegoe AL, KrausM,Hardy RR, Schlissel MS, Rajewsky K, Behrens TW (2005) Basal immunoglobulin signaling actively maintains developmental stage in immature B cells. PLoS Biol 3:e82
-
(2005)
PLoS Biol
, vol.3
-
-
Tze, L.E.1
Schram, B.R.2
Lam, K.P.3
Hogquist, K.A.4
Hippen, K.L.5
Liu, J.6
Shinton, S.A.7
Otipoby, K.L.8
Rodine, P.R.9
Vegoe, A.L.10
Kraus, M.11
Hardy, R.R.12
Schlissel, M.S.13
Rajewsky, K.14
Behrens, T.W.15
-
106
-
-
0032692949
-
Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice
-
Utomo AR, Nikitin AY, Lee WH (1999) Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice. Nat Biotechnol 17:1091-1096
-
(1999)
Nat Biotechnol
, vol.17
, pp. 1091-1096
-
-
Utomo, A.R.1
Nikitin, A.Y.2
Lee, W.H.3
-
107
-
-
0033587776
-
The magical touch: Genome targeting in epidermal stemcells induced by tamoxifen application tomouse skin
-
Vasioukhin V, Degenstein L, Wise B, Fuchs E (1999) The magical touch: genome targeting in epidermal stemcells induced by tamoxifen application tomouse skin. Proc Natl Acad Sci U S A 96:8551-8556
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8551-8556
-
-
Vasioukhin, V.1
Degenstein, L.2
Wise, B.3
Fuchs, E.4
-
108
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vives E, Brodin P, Lebleu B (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 272:16010-16017
-
(1997)
J Biol Chem
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
109
-
-
0038048992
-
Modulation of cellular function by TAT mediated transduction of full length proteins
-
Wadia JS, Dowdy SF (2003) Modulation of cellular function by TAT mediated transduction of full length proteins. Curr Protein Pept Sci 4:97-104
-
(2003)
Curr Protein Pept Sci
, vol.4
, pp. 97-104
-
-
Wadia, J.S.1
Dowdy, S.F.2
-
110
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
Wadia JS, Stan RV, Dowdy SF (2004) Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 10:310-315
-
(2004)
Nat Med
, vol.10
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
111
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB (2000) The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc Natl Acad Sci U S A 97:13003-13008
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
112
-
-
0037098648
-
Unmodified Cre recombinase crosses the membrane
-
Will E,KlumpH, HeffnerN, SchwiegerM, Schiedlmeier B, OstertagW, BaumC, StockingC (2002) Unmodified Cre recombinase crosses the membrane. Nucleic Acids Res 30:e59
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Will, E.1
Klump, H.2
Heffner, N.3
Schwieger, M.4
Schiedlmeier, B.5
Ostertag, W.6
Baum, C.7
Stocking, C.8
-
113
-
-
0030868695
-
Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide
-
Williams EJ, Dunican DJ, Green PJ, Howell FV, Derossi D, Walsh FS, Doherty P (1997) Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide. J Biol Chem 272:22349-22354
-
(1997)
J Biol Chem
, vol.272
, pp. 22349-22354
-
-
Williams, E.J.1
Dunican, D.J.2
Green, P.J.3
Howell, F.V.4
Derossi, D.5
Walsh, F.S.6
Doherty, P.7
-
114
-
-
0345598896
-
Distinct and nonoverlapping roles for pRB and cyclin D: Cyclin-dependent kinases 4/6 activity in melanocyte survival
-
Yu BD, Becker-Hapak M, Snyder EL, Vooijs M, Denicourt C, Dowdy SF (2003) Distinct and nonoverlapping roles for pRB and cyclin D:cyclin-dependent kinases 4/6 activity in melanocyte survival. Proc Natl Acad Sci U S A 100:14881-14886
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14881-14886
-
-
Yu, B.D.1
Becker-Hapak, M.2
Snyder, E.L.3
Vooijs, M.4
Denicourt, C.5
Dowdy, S.F.6
-
115
-
-
0034745384
-
P21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal
-
Zezula J, Casaccia-Bonnefil P, Ezhevsky SA, Osterhout DJ, Levine JM, Dowdy SF, Chao MV, Koff A (2001) p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal. EMBO Rep 2:27-34
-
(2001)
EMBO Rep
, vol.2
, pp. 27-34
-
-
Zezula, J.1
Casaccia-Bonnefil, P.2
Ezhevsky, S.A.3
Osterhout, D.J.4
Levine, J.M.5
Dowdy, S.F.6
Chao, M.V.7
Koff, A.8
|