Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans

Journal of Biological Chemistry

Volumn 278, Issue 37, 2003, Pages 35109-35114

  Console, Sandra ^a   Marty, Cornelia ^a   García Echeverría, Carlos ^b   Schwendener, Reto ^a   Ballmer Hofer, Kurt ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; PROTEINS; SYNTHESIS (CHEMICAL); VIRUSES;

PROTEIN TRANSDUCTION DOMAINS (PTD);

BIOCHEMISTRY;

ANTENNAPEDIA; DEXTRAN SULFATE; GLYCOSAMINOGLYCAN; HEPARIN; LIPOSOME; NANOPARTICLE; POLYNUCLEOTIDE; POLYPEPTIDE; PROTEIN TRANSDUCTION DOMAIN; PROTEOHEPARAN SULFATE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL MUTANT; CELL SURFACE; CELL TRANSPORT; CONTROLLED STUDY; ENDOCYTOSIS; GENETIC TRANSCRIPTION; GLYCOSAMINOGLYCAN METABOLISM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LIPID MEMBRANE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; TARGET CELL;

AMINO ACID SEQUENCE; ANIMALS; ANTENNAPEDIA HOMEODOMAIN PROTEIN; BINDING SITES; CELL MEMBRANE; DEXTRAN SULFATE; ENDOCYTOSIS; GENE PRODUCTS, TAT; GLYCOSAMINOGLYCANS; HELA CELLS; HEPARIN; HOMEODOMAIN PROTEINS; HUMANS; LYSOSOMES; MELANOMA, EXPERIMENTAL; MEMBRANE LIPIDS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PROTEIN TRANSPORT; RECEPTORS, TRANSFERRIN; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0041816277     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301726200     Document Type: Article

References (29)

1. Frankel, A. D., and Pabo, C. O. (1988) Cell 55, 1189-1193
2. Mann, D. A., and Frankel, A. D. (1991) EMBO J. 10, 1733-1739
3. Fischer, P. M., Krausz, E., and Lane, D. P. (2001) Bioconjugate Chem. 12, 825-841
4. Schwarze, S. R., Hruska, K. A., and Dowdy, S. F. (2000) Trends Cell Biol. 10, 290-295
5. Schwarze, S. R., and Dowdy, S. F. (2000) Trends Pharmacol. Sci. 21, 45-48
6. Derossi, D., Chassaing, G., and Prochiantz, A. (1998) Trends Cell Biol. 8, 84-87
7. Lindgren, M., Hallbrink, M., Prochiantz, A., and Langel, U. (2000) Trends Pharmacol. Sci. 21, 99-103
8. Vivès, E., Brodin, P., and Lebleu, B. (1997) J. Biol. Chem. 272, 16010-16017
9. Derossi, D., Calvet, S., Trembleau, A., Brunissen, A., Chassaing, G., and Prochiantz, A. (1996) J. Biol. Chem. 271, 18188-18193
10. Richard, J. P., Melikov, K., Vivès, E., Ramos, C., Verbeure, B., Gait, M. J., Chernomordik, L. V., and Lebleu, B. (2003) J. Biol. Chem. 278, 585-590
11. Lundberg, M., and Johansson, M. (2001) Nature Biotechnol. 19, 713-714
12. Rusnati, M., Tulipano, G., Urbinati, C., Tanghetti, E., Giuliani, R., Giacca, M., Ciomei, M., Corallini, A., and Presta, M. (1998) J. Biol. Chem. 273, 16027-16037
13. Rusnati, M., Tulipano, G., Spillmann, D., Tanghetti, E., Oreste, P., Zoppetti, G., Giacca, M., and Presta, M. (1999) J. Biol. Chem. 274, 28198-28205
14. Rusnati, M., Urbinati, C., Caputo, A., Possati, L., Lortat-Jacob, H., Giacca, M., Ribatti, D., and Presta, M. (2001) J. Biol. Chem. 276, 22420-22425
15. Suzuki, T., Futaki, S., Niwa, M., Tanaka, S., Ueda, K., and Sugiura, Y. (2002) J. Biol. Chem. 277, 2437-2443
16. Tyagi, M., Rusnati, M., Presta, M., and Giacca, M. (2001) J. Biol. Chem. 276, 3254-3261
17. Sandgren, S., Cheng, F., and Belting, M. (2002) J. Biol. Chem. 277, 38877-38883
18. Schweizer, A., Fransen, J. A., Bachi, T., Ginsel, L., and Hauri, H. P. (1988) J. Cell Biol. 107, 1643-1653
19. Vollenweider, F., Kappeler, F., Itin, C., and Hauri, H. P. (1998) J. Cell Biol. 142, 377-389
20. Esko, J. D., Stewart, T. E., and Taylor, W. H. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 3197-3201
21. Lidholt, K., Weinke, J. L., Kiser, C. S., Lugemwa, F. N., Bame, K. J., Cheifetz, S., Massague, J., Lindahl, U., and Esko, J. D. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 2267-2271
22. García-Echeverría, C. (1996) Bioorg. Med. Chem. Lett. 6, 229-232
23. García-Echeverría, C., Stamm, C., Wille, R., Arz, D., and Gay, B. (1997) Lett. Pept. Sci. 4, 49-53
24. Marty, C., Odermatt, B., Schott, H., Neri, D., Ballmer-Hofer, K., Klemenz, R., and Schwendener, R. A. (2002) Br. J. Cancer 87, 106-112
25. Hausser, H., and Kresse, H. (1999) Biochem. J. 344, 827-835
26. García-Echeverría, C., Jiang, L., Ramsey, T. M., Sharma, S. K., and Chen, Y. P. (2001) Bioorg. Med. Chem. Lett. 11, 1363-1366
27. Kramer, S. D., and Wunderli-Allenspach, H. (2003) Biochim. Biophys. Acta 1609, 161-169
28. Torchilin, V. P., Rammohan, R., Weissig, V., and Levchenko, T. S. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 8786-8791
29. Thoren, P. E., Persson, D., Karlsson, M., and Norden, B. (2000) FEBS Lett. 482, 265-268