메뉴 건너뛰기




Volumn 59, Issue 11, 1999, Pages 2577-2580

Transduced p16(INK4a) peptides inhibit hypophosphorylation of the retinoblastoma protein and cell cycle progression prior to activation of Cdk2 complexes in late G1

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P16; RETINOBLASTOMA PROTEIN; CDK2 PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; CDK6 PROTEIN, HUMAN; CYCLIN D; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN E; CYCLINE; ONCOPROTEIN; PROTEIN P16INK4A; PROTEIN SERINE THREONINE KINASE;

EID: 0033137321     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (119)

References (21)
  • 1
    • 0029033861 scopus 로고
    • The retínoblastoma protein and cell cycle control
    • Weinberg, R. A. The retínoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 2
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Washington DC
    • Sherr, C. J. Cancer cell cycles. Science (Washington DC), 274: 1672-1677, 1996.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 3
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr, C. J., and Roberts, J. M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev., 9: 1149-1163, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 4
    • 0025810049 scopus 로고
    • G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment
    • Mittnacht, S., and Weinberg, R. A. G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment. Cell, 65: 381-393, 1991.
    • (1991) Cell , vol.65 , pp. 381-393
    • Mittnacht, S.1    Weinberg, R.A.2
  • 5
    • 0028032069 scopus 로고
    • Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation
    • Mittnacht, S., Lees, J. A., Desai, D., Harlow, E., Morgan, D. O., and Weinberg, R. A. Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation. EMBO J., 13: 118-127, 1994.
    • (1994) EMBO J. , vol.13 , pp. 118-127
    • Mittnacht, S.1    Lees, J.A.2    Desai, D.3    Harlow, E.4    Morgan, D.O.5    Weinberg, R.A.6
  • 6
    • 0030924438 scopus 로고    scopus 로고
    • Hypo-phosphorylation of the retinoblastoma protein by cyclin D:Cdk4/6 complexes results in active pRb
    • Ezhevsky, S. A., Nagahara, H., Vocero-Akbani, A., Gius, D., Wei, M. C., and Dowdy, S. F. Hypo-phosphorylation of the retinoblastoma protein by cyclin D:cdk4/6 complexes results in active pRb. Proc. Natl. Acad. Sci. USA, 94: 10699-10704, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10699-10704
    • Ezhevsky, S.A.1    Nagahara, H.2    Vocero-Akbani, A.3    Gius, D.4    Wei, M.C.5    Dowdy, S.F.6
  • 7
    • 0029921317 scopus 로고    scopus 로고
    • Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
    • Hall, M., and Peters, G. Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv. Cancer Res., 68: 67-108, 1996.
    • (1996) Adv. Cancer Res. , vol.68 , pp. 67-108
    • Hall, M.1    Peters, G.2
  • 9
    • 0029177397 scopus 로고    scopus 로고
    • Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A
    • Fahraeus, R., Paramio, J. M., Ball, K. L., Lain, S., and Lane, D. P. Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A. Curr. Biol., 6: 84-91, 1996.
    • (1996) Curr. Biol. , vol.6 , pp. 84-91
    • Fahraeus, R.1    Paramio, J.M.2    Ball, K.L.3    Lain, S.4    Lane, D.P.5
  • 10
    • 0033013888 scopus 로고    scopus 로고
    • Killing HIV infected cells by direct transduction of an HIV protease-activated caspase-3 protein
    • Vocero-Akbani, A., Vander Heyden, N., Lissy, N. L., Ratner, L., and Dowdy, S. F. Killing HIV infected cells by direct transduction of an HIV protease-activated caspase-3 protein. Nat. Med., 5: 29-33, 1999.
    • (1999) Nat. Med. , vol.5 , pp. 29-33
    • Vocero-Akbani, A.1    Vander Heyden, N.2    Lissy, N.L.3    Ratner, L.4    Dowdy, S.F.5
  • 12
    • 0026567432 scopus 로고
    • The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression
    • DeCaprio, J. A., Furukawa, T., Ajchenbaum, F., Griffin, J. D., and Livingston, D. M. The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression. Proc. Natl. Acad. Sci. USA, 89: 1795-1798, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1795-1798
    • DeCaprio, J.A.1    Furukawa, T.2    Ajchenbaum, F.3    Griffin, J.D.4    Livingston, D.M.5
  • 13
    • 0023261635 scopus 로고
    • The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity
    • Lee, W. H., Shew, J. Y., Hong, F. D., Sery, T. W., Donoso, L. A., Young, L. J., Bookstein, R., and Lee, E. Y. The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity. Nature (Lond.), 329: 642-645, 1987.
    • (1987) Nature (Lond.) , vol.329 , pp. 642-645
    • Lee, W.H.1    Shew, J.Y.2    Hong, F.D.3    Sery, T.W.4    Donoso, L.A.5    Young, L.J.6    Bookstein, R.7    Lee, E.Y.8
  • 14
    • 0028909645 scopus 로고
    • Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
    • Ohtsubo, M., Theodoras, A. M., Schumacher, J., Roberts, J. M., and Pagano, M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol. Cell. Biol., 15: 2612-2624, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2612-2624
    • Ohtsubo, M.1    Theodoras, A.M.2    Schumacher, J.3    Roberts, J.M.4    Pagano, M.5
  • 15
    • 0029052951 scopus 로고
    • Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition
    • Koh, J., Enders, G. H., Dynlacht, B. D., and Harlow, E. Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature (Lond.), 375: 506-510, 1995.
    • (1995) Nature (Lond.) , vol.375 , pp. 506-510
    • Koh, J.1    Enders, G.H.2    Dynlacht, B.D.3    Harlow, E.4
  • 17
    • 0028983491 scopus 로고
    • Growth suppression by p16ink4 requires functional retinoblastoma protein
    • Medema, R. H., Herrera, R. E., Lam, F., and Weinberg, R. A. Growth suppression by p16ink4 requires functional retinoblastoma protein. Proc. Natl. Acad. Sci. USA, 92: 6289-6293, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6289-6293
    • Medema, R.H.1    Herrera, R.E.2    Lam, F.3    Weinberg, R.A.4
  • 18
    • 0002212059 scopus 로고    scopus 로고
    • Cell cycle synchronization by elutriation
    • K. Adolph (ed.). Boca Raton, FL: CRC Press
    • Dowdy, S. F., Van Dyk, L., and Schreiber, G. H. Cell cycle synchronization by elutriation. In: K. Adolph (ed.). Human Genome Methods, pp. 121-132. Boca Raton, FL: CRC Press, 1997.
    • (1997) Human Genome Methods , pp. 121-132
    • Dowdy, S.F.1    Van Dyk, L.2    Schreiber, G.H.3
  • 19
    • 0026699554 scopus 로고
    • Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts
    • Won, K. A., Xiong, Y., Beach, D., and Gilman M. Z. Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc. Natl. Acad. Sci. USA, 89: 9910-9914, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9910-9914
    • Won, K.A.1    Xiong, Y.2    Beach, D.3    Gilman, M.Z.4
  • 20
    • 0027523623 scopus 로고
    • Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes
    • Ajchenbaum, F., Ando, K., DeCaprio, J. A., and Griffin, J. D. Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes. J. Biol. Chem., 268: 4113-4119, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4113-4119
    • Ajchenbaum, F.1    Ando, K.2    DeCaprio, J.A.3    Griffin, J.D.4
  • 21
    • 0029868367 scopus 로고    scopus 로고
    • A unique role for the pRb protein in controlling E2F accumulation during cell growth and differentiation
    • Ikeda, M. A., Jakoi, L., and Nevins, J. R. A unique role for the pRb protein in controlling E2F accumulation during cell growth and differentiation. Proc. Natl. Acad. Sci. USA, 93: 3215-3220, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3215-3220
    • Ikeda, M.A.1    Jakoi, L.2    Nevins, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.