Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins

Biochemical and Biophysical Research Communications

Volumn 319, Issue 1, 2004, Pages 12-20

  Caron, Nicolas J ^a   Quenneville, Simon P ^a   Tremblay, Jacques P ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Chloroquine; Cre recombinase; Endocytosis; Lysosomotropic agents; Perinuclear accumulation; Tat; Transduction; Uptake

Indexed keywords

CRE RECOMBINASE; HYBRID PROTEIN; TRANSACTIVATOR PROTEIN;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CELL DISRUPTION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; DEGRADATION; EMBRYO; ENDOCYTOSIS; ENDOSOME; INTERNALIZATION; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN TARGETING; TEMPERATURE SENSITIVITY;

ANIMALS; CELL NUCLEUS; CHLOROQUINE; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; ENDOSOMES; ENZYME INHIBITORS; GENE PRODUCTS, TAT; GENE TRANSFER TECHNIQUES; IMMUNOBLOTTING; INTEGRASES; KINETICS; LEUPEPTINS; LYSOSOMES; MACROLIDES; MICE; NIH 3T3 CELLS; RECOMBINANT FUSION PROTEINS; SUCROSE; TEMPERATURE; TIME FACTORS; VIRAL PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 2442670068     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.180     Document Type: Article

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