메뉴 건너뛰기




Volumn 215, Issue 1, 2007, Pages 136-153

Intraepithelial lymphocytes: Their shared and divergent immunological behaviors in the small and large intestine

Author keywords

Classical and non classical MHC; Development trafficking; Intraepithelial T lymphocyte (IEL); Small and large intestines

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN A; INTEGRIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR;

EID: 33846798312     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/j.1600-065X.2006.00475.x     Document Type: Review
Times cited : (87)

References (175)
  • 1
    • 24144441757 scopus 로고    scopus 로고
    • Mucosa-associated lymphoid tissues in the aerodigestive tract: Their shared and divergent traits and their importance to the orchestration of the mucosal immune system
    • Kunisawa J, Fukuyama S, Kiyono H. Mucosa-associated lymphoid tissues in the aerodigestive tract: their shared and divergent traits and their importance to the orchestration of the mucosal immune system. Curr Mol Med 2005;5:557-572.
    • (2005) Curr Mol Med , vol.5 , pp. 557-572
    • Kunisawa, J.1    Fukuyama, S.2    Kiyono, H.3
  • 2
    • 4544258068 scopus 로고    scopus 로고
    • NALT- versus Peyer's-patch-mediated mucosal immunity
    • Kiyono H, Fukuyama S. NALT- versus Peyer's-patch-mediated mucosal immunity. Nat Rev Immunol 2004;4:699-710.
    • (2004) Nat Rev Immunol , vol.4 , pp. 699-710
    • Kiyono, H.1    Fukuyama, S.2
  • 3
    • 0030000550 scopus 로고    scopus 로고
    • Antigen sampling across epithelial barriers and induction of mucosal immune responses
    • Neutra MR, Pringault E, Kraehenbuhl JP. Antigen sampling across epithelial barriers and induction of mucosal immune responses. Annu Rev Immunol 1996;14:275-300.
    • (1996) Annu Rev Immunol , vol.14 , pp. 275-300
    • Neutra, M.R.1    Pringault, E.2    Kraehenbuhl, J.P.3
  • 4
    • 33846843144 scopus 로고    scopus 로고
    • Kunisawa J, McGhee J, Kiyono H. Mucosal S-IgA enhancement: development of safe and effective mucosal adjuvants and mucosal antigen delivery vehicles. In: Kaetzel C, ed. Mucosal Immune. Defense: Immunoglobubin A. London: Kluwer Academic/Plenum Publishers, 2006; in press.
    • Kunisawa J, McGhee J, Kiyono H. Mucosal S-IgA enhancement: development of safe and effective mucosal adjuvants and mucosal antigen delivery vehicles. In: Kaetzel C, ed. Mucosal Immune. Defense: Immunoglobubin A. London: Kluwer Academic/Plenum Publishers, 2006; in press.
  • 5
    • 0037369552 scopus 로고    scopus 로고
    • Intestinal epithelial responses to enteric pathogens: Effects on the tight junction barrier, ion transport, and inflammation
    • Berkes J, Viswanathan VK, Savkovic SD, Hecht G. Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut 2003;52:439-451.
    • (2003) Gut , vol.52 , pp. 439-451
    • Berkes, J.1    Viswanathan, V.K.2    Savkovic, S.D.3    Hecht, G.4
  • 6
    • 0041807542 scopus 로고    scopus 로고
    • Characteristics of claudin expression in follicle-associated epithelium of Peyer's patches: Preferential localization of claudin-4 at the apex of the dome region
    • Tamagawa H, et al. Characteristics of claudin expression in follicle-associated epithelium of Peyer's patches: preferential localization of claudin-4 at the apex of the dome region. Lab Invest 2003;83:1045-1053.
    • (2003) Lab Invest , vol.83 , pp. 1045-1053
    • Tamagawa, H.1
  • 7
    • 0033043785 scopus 로고    scopus 로고
    • Mouse β-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs
    • Bals R, et al. Mouse β-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs. Infect Immun 1999;67:3542-3547.
    • (1999) Infect Immun , vol.67 , pp. 3542-3547
    • Bals, R.1
  • 8
    • 20744453946 scopus 로고    scopus 로고
    • A marvel of mucosal T cells and secretory antibodies for the creation of first lines of defense
    • Kunisawa J, Kiyono H. A marvel of mucosal T cells and secretory antibodies for the creation of first lines of defense. Cell Mol Life Sci 2005;62:1308-1321.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1308-1321
    • Kunisawa, J.1    Kiyono, H.2
  • 9
    • 0015231977 scopus 로고
    • Immunoglobulin M and secretory immunoglobulin A: Presence of a common polypeptide chain different from light chains
    • Mestecky J, Zikan J, Butler WT. Immunoglobulin M and secretory immunoglobulin A: presence of a common polypeptide chain different from light chains. Science 1971;171:1163-1165.
    • (1971) Science , vol.171 , pp. 1163-1165
    • Mestecky, J.1    Zikan, J.2    Butler, W.T.3
  • 10
    • 0014964145 scopus 로고
    • Noval subunit in secretory IgA
    • Halpern MS, Koshland ME. Noval subunit in secretory IgA. Nature 1970;228:1276-1278.
    • (1970) Nature , vol.228 , pp. 1276-1278
    • Halpern, M.S.1    Koshland, M.E.2
  • 11
    • 0033556253 scopus 로고    scopus 로고
    • Deficiency of IL-5 receptor α-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues
    • Hiroi T, et al. Deficiency of IL-5 receptor α-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues. J Immunol 1999;162:821-828.
    • (1999) J Immunol , vol.162 , pp. 821-828
    • Hiroi, T.1
  • 12
    • 0035314006 scopus 로고    scopus 로고
    • B1 cells: Similarities and differences with other B cell subsets
    • Martin F, Kearney JF. B1 cells: similarities and differences with other B cell subsets. Curr Opin Immunol 2001;13:195-201.
    • (2001) Curr Opin Immunol , vol.13 , pp. 195-201
    • Martin, F.1    Kearney, J.F.2
  • 13
    • 26244467481 scopus 로고    scopus 로고
    • All the peptides that fit: The beginning, the middle, and the end of the MHC class I antigen-processing pathway
    • Shastri N, Cardinaud S, Schwab SR, Serwold T, Kunisawa J. All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway. Immunol Rev 2005;207:31-41.
    • (2005) Immunol Rev , vol.207 , pp. 31-41
    • Shastri, N.1    Cardinaud, S.2    Schwab, S.R.3    Serwold, T.4    Kunisawa, J.5
  • 15
    • 0029063552 scopus 로고
    • Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine
    • Beagley KW, et al. Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine. J Immunol 1995;154:5611-5619.
    • (1995) J Immunol , vol.154 , pp. 5611-5619
    • Beagley, K.W.1
  • 16
    • 0027182537 scopus 로고
    • CD2 expression on murine intestinal intraepithelial lymphocytes is bimodal and defines proliferative capacity
    • Van Houten N, Mixter PF, Wolfe J, Budd RC. CD2 expression on murine intestinal intraepithelial lymphocytes is bimodal and defines proliferative capacity. Int Immunol 1993;5:665-672.
    • (1993) Int Immunol , vol.5 , pp. 665-672
    • Van Houten, N.1    Mixter, P.F.2    Wolfe, J.3    Budd, R.C.4
  • 17
    • 0027309199 scopus 로고
    • Expression of the CD28 costimulatory molecule on subsets of murine intestinal intraepithelial lymphocytes correlates with lineage and responsiveness
    • Ohteki T, MacDonald HR. Expression of the CD28 costimulatory molecule on subsets of murine intestinal intraepithelial lymphocytes correlates with lineage and responsiveness. Eur J Immunol 1993;23:1251-1255.
    • (1993) Eur J Immunol , vol.23 , pp. 1251-1255
    • Ohteki, T.1    MacDonald, H.R.2
  • 18
    • 0034741125 scopus 로고    scopus 로고
    • + intraepithelial lymphocytes provided by serial analysis of gene expression (SAGE)
    • + intraepithelial lymphocytes provided by serial analysis of gene expression (SAGE). Immunity 2001;15:419-434.
    • (2001) Immunity , vol.15 , pp. 419-434
    • Shires, J.1    Theodoridis, E.2    Hayday, A.C.3
  • 19
    • 0022541271 scopus 로고
    • + murine intestinal intraepithelial lymphocyte. Characterization of a unique population of thymus-independent cytotoxic effector cells in the intestinal mucosa
    • + murine intestinal intraepithelial lymphocyte. Characterization of a unique population of thymus-independent cytotoxic effector cells in the intestinal mucosa. J Exp Med 1986;164:309-314.
    • (1986) J Exp Med , vol.164 , pp. 309-314
    • Klein, J.R.1
  • 20
    • 0035976604 scopus 로고    scopus 로고
    • T cell responses modulated through interaction between CD8αα and the nonclassical MHC class I molecule, TL
    • Leishman AJ, et al. T cell responses modulated through interaction between CD8αα and the nonclassical MHC class I molecule, TL. Science 2001;294:1936-1939.
    • (2001) Science , vol.294 , pp. 1936-1939
    • Leishman, A.J.1
  • 22
    • 0019976727 scopus 로고
    • Characteristics of natural killer cells in the murine intestinal epithelium and lamina propria
    • Tagliabue A, Befus AD, Clark DA, Bienenstock J. Characteristics of natural killer cells in the murine intestinal epithelium and lamina propria. J Exp Med 1982;155:1785-1796.
    • (1982) J Exp Med , vol.155 , pp. 1785-1796
    • Tagliabue, A.1    Befus, A.D.2    Clark, D.A.3    Bienenstock, J.4
  • 23
    • 0029848909 scopus 로고    scopus 로고
    • Complexity of the mouse gut T cell immune system: Identification of two distinct natural killer T cell intraepithelial lineages
    • Guy-Grand D, Cuenod-Jabri B, Malassis-Seris M, Selz F, Vassalli P. Complexity of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages. Eur J Immunol 1996;26:2248-2256.
    • (1996) Eur J Immunol , vol.26 , pp. 2248-2256
    • Guy-Grand, D.1    Cuenod-Jabri, B.2    Malassis-Seris, M.3    Selz, F.4    Vassalli, P.5
  • 24
    • 0029131501 scopus 로고
    • Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium
    • Lundqvist C, Baranov V, Hammarstrom S, Athlin L, Hammarstrom ML. Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium. Int Immunol 1995;7:1473-1487.
    • (1995) Int Immunol , vol.7 , pp. 1473-1487
    • Lundqvist, C.1    Baranov, V.2    Hammarstrom, S.3    Athlin, L.4    Hammarstrom, M.L.5
  • 25
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer S, et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 1999;285:727-729.
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1
  • 26
    • 0032513388 scopus 로고    scopus 로고
    • Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells
    • Groh V, Steinle A, Bauer S, Spies T. Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells. Science 1998;279:1737-1740.
    • (1998) Science , vol.279 , pp. 1737-1740
    • Groh, V.1    Steinle, A.2    Bauer, S.3    Spies, T.4
  • 27
    • 0034897362 scopus 로고    scopus 로고
    • MICA engagement by human Vγ2Vδ2 T cells enhances their antigen-dependent effector function
    • Das H, et al. MICA engagement by human Vγ2Vδ2 T cells enhances their antigen-dependent effector function. Immunity 2001;15:83-93.
    • (2001) Immunity , vol.15 , pp. 83-93
    • Das, H.1
  • 28
    • 0036884144 scopus 로고    scopus 로고
    • Autocrine IL-15 mediates intestinal epithelial cell death via the activation of neighboring intraepithelial NK cells
    • Kinoshita N, Hiroi T, Ohta N, Fukuyama S, Park EJ, Kiyono H. Autocrine IL-15 mediates intestinal epithelial cell death via the activation of neighboring intraepithelial NK cells. J Immunol 2002;169:6187-6192.
    • (2002) J Immunol , vol.169 , pp. 6187-6192
    • Kinoshita, N.1    Hiroi, T.2    Ohta, N.3    Fukuyama, S.4    Park, E.J.5    Kiyono, H.6
  • 29
    • 4444240035 scopus 로고    scopus 로고
    • Coordinated induction by IL-5 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease
    • Meresse B, et al. Coordinated induction by IL-5 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity 2004;21:357-366.
    • (2004) Immunity , vol.21 , pp. 357-366
    • Meresse, B.1
  • 30
    • 4444251461 scopus 로고    scopus 로고
    • A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease
    • Hue S, et al. A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity 2004;21:367-377.
    • (2004) Immunity , vol.21 , pp. 367-377
    • Hue, S.1
  • 31
    • 17844388888 scopus 로고    scopus 로고
    • IL-15 converts human intestinal intraepithelial lymphocytes to CD94 producers of IFN-γ and IL-10, the latter promoting Fas ligand-mediated cytotoxicity
    • Ebert EC. IL-15 converts human intestinal intraepithelial lymphocytes to CD94 producers of IFN-γ and IL-10, the latter promoting Fas ligand-mediated cytotoxicity. Immunology 2005;115:118-126.
    • (2005) Immunology , vol.115 , pp. 118-126
    • Ebert, E.C.1
  • 33
    • 2942567923 scopus 로고    scopus 로고
    • + recent thymic emigrants are αE integrin-positive and CC chemokine ligand 25 responsive
    • + recent thymic emigrants are αE integrin-positive and CC chemokine ligand 25 responsive. J Immunol 2004;172:7282-7288.
    • (2004) J Immunol , vol.172 , pp. 7282-7288
    • Staton, T.L.1    Johnston, B.2    Butcher, E.C.3    Campbell, D.J.4
  • 34
    • 0027163734 scopus 로고
    • Regional specialization of the mucosal immune system. Intraepithelial lymphocytes of the large intestine have a different phenotype and function than those of the small intestine
    • Camerini V, Panwala C, Kronenberg M. Regional specialization of the mucosal immune system. Intraepithelial lymphocytes of the large intestine have a different phenotype and function than those of the small intestine. J Immunol 1993;151:1765-1776.
    • (1993) J Immunol , vol.151 , pp. 1765-1776
    • Camerini, V.1    Panwala, C.2    Kronenberg, M.3
  • 35
    • 0032520267 scopus 로고    scopus 로고
    • Generation of intestinal mucosal lymphocytes in SCID mice reconstituted with mature, thymus-derived T cells
    • Camerini V, et al. Generation of intestinal mucosal lymphocytes in SCID mice reconstituted with mature, thymus-derived T cells. J Immunol 1998;160:2608-2618.
    • (1998) J Immunol , vol.160 , pp. 2608-2618
    • Camerini, V.1
  • 36
    • 0028238361 scopus 로고
    • + cells from murine large intestine: Implications for functional state
    • + cells from murine large intestine: implications for functional state. J Exp Med 1994;180:433-444.
    • (1994) J Exp Med , vol.180 , pp. 433-444
    • Ibraghimov, A.R.1    Lynch, R.G.2
  • 38
    • 2142756661 scopus 로고    scopus 로고
    • CD8aa-mediated survival and differentiation of CD8 memory T cell precursors
    • Madakamutil LT, et al. CD8aa-mediated survival and differentiation of CD8 memory T cell precursors. Science 2004;304:590-593.
    • (2004) Science , vol.304 , pp. 590-593
    • Madakamutil, L.T.1
  • 39
    • 0034610972 scopus 로고    scopus 로고
    • Identical T cell clones are located within the mouse gut epithelium and lamina propia and circulate in the thoracic duct lymph
    • Arstila T, et al. Identical T cell clones are located within the mouse gut epithelium and lamina propia and circulate in the thoracic duct lymph. J Exp Med 2000;191:823-834.
    • (2000) J Exp Med , vol.191 , pp. 823-834
    • Arstila, T.1
  • 40
    • 0028170171 scopus 로고
    • Oligoclonal repertoire of the CD8αα and the CD8αβ TCR-α/β murine intestinal intraepithelial T lymphocytes: Evidence for the random emergence of T cells
    • Regnault A, Cumano A, Vassalli P, Guy-Grand D, Kourilsky P. Oligoclonal repertoire of the CD8αα and the CD8αβ TCR-α/β murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells. J Exp Med 1994;180:1345-1358.
    • (1994) J Exp Med , vol.180 , pp. 1345-1358
    • Regnault, A.1    Cumano, A.2    Vassalli, P.3    Guy-Grand, D.4    Kourilsky, P.5
  • 41
    • 0025974008 scopus 로고
    • The Vβ repertoire of mouse gut homodimeric α CD8+ intraepithelial T cell receptor α/β + lymphocytes reveals a major extrathymic pathway of T cell differentiation
    • Rocha B, Vassalli P, Guy-Grand D. The Vβ repertoire of mouse gut homodimeric α CD8+ intraepithelial T cell receptor α/β + lymphocytes reveals a major extrathymic pathway of T cell differentiation. J Exp Med 1991;173:483-486.
    • (1991) J Exp Med , vol.173 , pp. 483-486
    • Rocha, B.1    Vassalli, P.2    Guy-Grand, D.3
  • 42
    • 0030578446 scopus 로고    scopus 로고
    • Thymus ontogeny and the development of TCRαβ intestinal intraepithelial lymphocytes
    • Lin T, et al. Thymus ontogeny and the development of TCRαβ intestinal intraepithelial lymphocytes. Cell Immunol 1996;171:132-139.
    • (1996) Cell Immunol , vol.171 , pp. 132-139
    • Lin, T.1
  • 43
    • 0028177912 scopus 로고
    • High frequency of CD8αα homodimer-bearing T cells in human fetal intestine
    • Latthe M, Terry L, MacDonald TT. High frequency of CD8αα homodimer-bearing T cells in human fetal intestine. Eur J Immunol 1994;24:1703-1705.
    • (1994) Eur J Immunol , vol.24 , pp. 1703-1705
    • Latthe, M.1    Terry, L.2    MacDonald, T.T.3
  • 44
    • 0029970242 scopus 로고    scopus 로고
    • Proliferative recruitment of intestinal intraepithelial lymphocytes after microbial colonization of germ-free mice
    • Imaoka A, Matsumoto S, Setoyama H, Okada Y, Umesaki Y. Proliferative recruitment of intestinal intraepithelial lymphocytes after microbial colonization of germ-free mice. Eur J Immunol 1996;26:945-948.
    • (1996) Eur J Immunol , vol.26 , pp. 945-948
    • Imaoka, A.1    Matsumoto, S.2    Setoyama, H.3    Okada, Y.4    Umesaki, Y.5
  • 47
    • 0030584690 scopus 로고    scopus 로고
    • Development of CD8αα+ intestinal intraepithelial T cells in β2-microglobulin-and/or TAP1-deficient mice
    • Fujiura Y, et al. Development of CD8αα+ intestinal intraepithelial T cells in β2-microglobulin-and/or TAP1-deficient mice. J Immunol 1996;156:2710-2715.
    • (1996) J Immunol , vol.156 , pp. 2710-2715
    • Fujiura, Y.1
  • 48
    • 0029098550 scopus 로고
    • Control of thymus-independent intestinal intraepithelial lymphocytes by β2-microglobulin
    • Neuhaus O, Emoto M, Blum C, Yamamoto S, Kaufmann SH. Control of thymus-independent intestinal intraepithelial lymphocytes by β2-microglobulin. Eur J Immunol 1995;25:2332-2339.
    • (1995) Eur J Immunol , vol.25 , pp. 2332-2339
    • Neuhaus, O.1    Emoto, M.2    Blum, C.3    Yamamoto, S.4    Kaufmann, S.H.5
  • 50
    • 0033588547 scopus 로고    scopus 로고
    • + intestinal intraepithelial lymphocytes in the absence of both classical major histocompatibility complex class I and nonclassical CD1 molecules
    • + intestinal intraepithelial lymphocytes in the absence of both classical major histocompatibility complex class I and nonclassical CD1 molecules. J Exp Med 1999;190:885-890.
    • (1999) J Exp Med , vol.190 , pp. 885-890
    • Park, S.H.1    Guy-Grand, D.2    Lemonnier, F.A.3    Wang, C.R.4    Bendelac, A.5    Jabri, B.6
  • 51
    • 0032846123 scopus 로고    scopus 로고
    • + T cells are found in intestinal intraepithelial lymphocytes of mice that lack classical MHC class I molecules. J Immunol 1999;163:4100-4104.
    • + T cells are found in intestinal intraepithelial lymphocytes of mice that lack classical MHC class I molecules. J Immunol 1999;163:4100-4104.
  • 52
    • 0028236271 scopus 로고
    • Expression of secreted and glycosylphosphatidylinositol-bound Qa-2 molecules is dependent on functional TAP-2 peptide transporter
    • Tabaczewski P, Stroynowski I. Expression of secreted and glycosylphosphatidylinositol-bound Qa-2 molecules is dependent on functional TAP-2 peptide transporter. J Immunol 1994;152:5268-5274.
    • (1994) J Immunol , vol.152 , pp. 5268-5274
    • Tabaczewski, P.1    Stroynowski, I.2
  • 53
    • 0034694026 scopus 로고    scopus 로고
    • Qa-2-dependent selection of CD8αα T cell receptor α/β(+) cells in murine intestinal intraepithelial lymphocytes
    • Das G, et al. Qa-2-dependent selection of CD8αα T cell receptor α/β(+) cells in murine intestinal intraepithelial lymphocytes. J Exp Med 2000;192:1521-1528.
    • (2000) J Exp Med , vol.192 , pp. 1521-1528
    • Das, G.1
  • 54
    • 23344451487 scopus 로고    scopus 로고
    • Cheroutre H. IELs: enforcing law and order in the court of the intestinal epithelium. Immunol Rev 2005;206:114-131.
    • Cheroutre H. IELs: enforcing law and order in the court of the intestinal epithelium. Immunol Rev 2005;206:114-131.
  • 55
    • 0025599926 scopus 로고
    • Expression of the thymus leukemia antigen in mouse intestinal epithelium
    • Hershberg R, et al. Expression of the thymus leukemia antigen in mouse intestinal epithelium. Proc Natl Acad Sci USA 1990;87:9727-9731.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9727-9731
    • Hershberg, R.1
  • 57
    • 0031203340 scopus 로고    scopus 로고
    • Mouse CD1 is mainly expressed on hemopoietic-derived cells
    • Brossay L, et al. Mouse CD1 is mainly expressed on hemopoietic-derived cells. J Immunol 1997;159:1216-1224.
    • (1997) J Immunol , vol.159 , pp. 1216-1224
    • Brossay, L.1
  • 58
    • 0028970661 scopus 로고
    • TAP-independent, β2-microglobulin-dependent surface expression of functional mouse CD1.1
    • Brutkiewicz RR, Bennink JR, Yewdell JW, Bendelac A. TAP-independent, β2-microglobulin-dependent surface expression of functional mouse CD1.1. J Exp Med 1995;182:1913-1919.
    • (1995) J Exp Med , vol.182 , pp. 1913-1919
    • Brutkiewicz, R.R.1    Bennink, J.R.2    Yewdell, J.W.3    Bendelac, A.4
  • 59
    • 0028966765 scopus 로고
    • Nonclassical behavior of the thymus leukemia antigen: Peptide transporter-independent expression of a nonclassical class I molecule
    • Holcombe HR, et al. Nonclassical behavior of the thymus leukemia antigen: peptide transporter-independent expression of a nonclassical class I molecule. J Exp Med 1995;181:1433-1443.
    • (1995) J Exp Med , vol.181 , pp. 1433-1443
    • Holcombe, H.R.1
  • 60
    • 0031093564 scopus 로고    scopus 로고
    • Nonclassical behavior of the mouse CD1 class I-like molecule
    • Teitell M, et al. Nonclassical behavior of the mouse CD1 class I-like molecule. J Immunol 1997;158:2143-2149.
    • (1997) J Immunol , vol.158 , pp. 2143-2149
    • Teitell, M.1
  • 61
    • 0037331174 scopus 로고    scopus 로고
    • The crystal structure of a TL/CD8αα complex at 2.1 A resolution: Implications for modulation of T cell activation and memory
    • Liu Y, et al. The crystal structure of a TL/CD8αα complex at 2.1 A resolution: implications for modulation of T cell activation and memory. Immunity 2003;18:205-215.
    • (2003) Immunity , vol.18 , pp. 205-215
    • Liu, Y.1
  • 62
    • 0034801716 scopus 로고    scopus 로고
    • Contribution of double-negative thymic precursors to CD8αα(+) intraepithelial lymphocytes of the gut in mice bearing TCR transgenes
    • Guy-Grand D, Pardigon N, Darche S, Lantz O, Kourilsky P, Vassalli P. Contribution of double-negative thymic precursors to CD8αα(+) intraepithelial lymphocytes of the gut in mice bearing TCR transgenes. Eur J Immunol 2001;31:2593-2602.
    • (2001) Eur J Immunol , vol.31 , pp. 2593-2602
    • Guy-Grand, D.1    Pardigon, N.2    Darche, S.3    Lantz, O.4    Kourilsky, P.5    Vassalli, P.6
  • 63
    • 0036199258 scopus 로고    scopus 로고
    • Precursors of functional MHC class I- or class II-restricted CD8αα(+) T cells are positively selected in the thymus by agonist self-peptides
    • Leishman AJ, et al. Precursors of functional MHC class I- or class II-restricted CD8αα(+) T cells are positively selected in the thymus by agonist self-peptides. Immunity 2002;16:355-364.
    • (2002) Immunity , vol.16 , pp. 355-364
    • Leishman, A.J.1
  • 64
    • 0025730698 scopus 로고
    • The immunobiology of T cells with invariant γδ antigen receptors
    • Allison JP, Havran WL. The immunobiology of T cells with invariant γδ antigen receptors. Annu Rev Immunol 1991;9:679-705.
    • (1991) Annu Rev Immunol , vol.9 , pp. 679-705
    • Allison, J.P.1    Havran, W.L.2
  • 65
    • 0024440089 scopus 로고
    • Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells
    • Asarnow DM, Goodman T, LeFrancois L, Allison JP. Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells. Nature 1989;341:60-62.
    • (1989) Nature , vol.341 , pp. 60-62
    • Asarnow, D.M.1    Goodman, T.2    LeFrancois, L.3    Allison, J.P.4
  • 68
    • 0032514613 scopus 로고    scopus 로고
    • Diversification, expression, and γδ T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility complex class I-related molecules
    • Steinle A, Groh V, Spies T. Diversification, expression, and γδ T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility complex class I-related molecules. Proc Natl Acad Sci USA 1998;95:12510-12515.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12510-12515
    • Steinle, A.1    Groh, V.2    Spies, T.3
  • 69
    • 0036681809 scopus 로고    scopus 로고
    • T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial γδ T cells
    • Wu J, Groh V, Spies T. T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial γδ T cells. J Immunol 2002;169:1236-1240.
    • (2002) J Immunol , vol.169 , pp. 1236-1240
    • Wu, J.1    Groh, V.2    Spies, T.3
  • 70
    • 0034252303 scopus 로고    scopus 로고
    • Ligands for the murine NKG2D receptor: Expression by tumor cells and activation of NK cells and macrophages
    • Diefenbach A, Jamieson AM, Liu SD, Shastri N, Raulet DH. Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat Immunol 2000;1:119-126.
    • (2000) Nat Immunol , vol.1 , pp. 119-126
    • Diefenbach, A.1    Jamieson, A.M.2    Liu, S.D.3    Shastri, N.4    Raulet, D.H.5
  • 71
    • 0033672658 scopus 로고    scopus 로고
    • Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice
    • Cerwenka A, et al. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 2000;12:721- 727.
    • (2000) Immunity , vol.12 , pp. 721-727
    • Cerwenka, A.1
  • 72
    • 0036786444 scopus 로고    scopus 로고
    • Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity
    • Cawthon AG, Alexander-Miller MA. Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity. J Immunol 2002;169:3492-3498.
    • (2002) J Immunol , vol.169 , pp. 3492-3498
    • Cawthon, A.G.1    Alexander-Miller, M.A.2
  • 73
    • 0035914485 scopus 로고    scopus 로고
    • CD8β endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes
    • Arcaro A, et al. CD8β endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes. J Exp Med 2001;194:1485-1495.
    • (2001) J Exp Med , vol.194 , pp. 1485-1495
    • Arcaro, A.1
  • 74
    • 0025869912 scopus 로고
    • Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells
    • Wu M, van Kaer L, Itohara S, Tonegawa S. Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells. J Exp Med 1991;174:213-218.
    • (1991) J Exp Med , vol.174 , pp. 213-218
    • Wu, M.1    van Kaer, L.2    Itohara, S.3    Tonegawa, S.4
  • 75
    • 0141923719 scopus 로고    scopus 로고
    • Clonal expansion of double-positive intraepithelial lymphocytes by MHC class I-related chain A expressed in mouse small intestinal epithelium
    • Park EJ, et al. Clonal expansion of double-positive intraepithelial lymphocytes by MHC class I-related chain A expressed in mouse small intestinal epithelium. J Immunol 2003;171:4131-4139.
    • (2003) J Immunol , vol.171 , pp. 4131-4139
    • Park, E.J.1
  • 76
    • 0029861713 scopus 로고    scopus 로고
    • Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium
    • Groh V, Bahram S, Bauer S, Herman A, Beauchamp M, Spies T. Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium. Proc Natl Acad Sci USA 1996;93:12445- 12450.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12445-12450
    • Groh, V.1    Bahram, S.2    Bauer, S.3    Herman, A.4    Beauchamp, M.5    Spies, T.6
  • 77
    • 0028356473 scopus 로고
    • Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation
    • Guy-Grand D, et al. Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation. J Exp Med 1994;180:673-679.
    • (1994) J Exp Med , vol.180 , pp. 673-679
    • Guy-Grand, D.1
  • 78
    • 0027432384 scopus 로고
    • -/- mutant mice and identification of a novel T cell population in the intestine
    • -/- mutant mice and identification of a novel T cell population in the intestine. EMBO J 1993;12:4863-4875.
    • (1993) EMBO J , vol.12 , pp. 4863-4875
    • Liu, C.P.1
  • 79
    • 0031570121 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J Immunol 1997;158:4678-4687.
    • (1997) J Immunol , vol.158 , pp. 4678-4687
    • She, J.1
  • 80
    • 0028107255 scopus 로고
    • Preferential usage of the Fc receptor γ chain in the T cell antigen receptor complex by γ/δ T cells localized in epithelia
    • Ohno H, Ono S, Hirayama N, Shimada S, Saito T. Preferential usage of the Fc receptor γ chain in the T cell antigen receptor complex by γ/δ T cells localized in epithelia. J Exp Med 1994;179:365- 369.
    • (1994) J Exp Med , vol.179 , pp. 365-369
    • Ohno, H.1    Ono, S.2    Hirayama, N.3    Shimada, S.4    Saito, T.5
  • 81
    • 0029936945 scopus 로고    scopus 로고
    • Positive selection is not required for thymic maturation of transgenic γδ T cells
    • Schweighoffer E, Fowlkes BJ. Positive selection is not required for thymic maturation of transgenic γδ T cells. J Exp Med 1996;183:2033-2041.
    • (1996) J Exp Med , vol.183 , pp. 2033-2041
    • Schweighoffer, E.1    Fowlkes, B.J.2
  • 82
    • 0346103710 scopus 로고    scopus 로고
    • Thymic selection and peripheral activation of CD8 T cells by the same class I MHC/peptide complex
    • Mintern JD, Maurice MM, Ploegh HL, Schott E. Thymic selection and peripheral activation of CD8 T cells by the same class I MHC/peptide complex. J Immunol 2004;172:699-708.
    • (2004) J Immunol , vol.172 , pp. 699-708
    • Mintern, J.D.1    Maurice, M.M.2    Ploegh, H.L.3    Schott, E.4
  • 83
    • 0031821756 scopus 로고    scopus 로고
    • An opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes
    • Cruz D, Sydora BC, Hetzel K, Yakoub G, Kronenberg M, Cheroutre H. An opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes. J Exp Med 1998;188:255-265.
    • (1998) J Exp Med , vol.188 , pp. 255-265
    • Cruz, D.1    Sydora, B.C.2    Hetzel, K.3    Yakoub, G.4    Kronenberg, M.5    Cheroutre, H.6
  • 84
    • 0029789386 scopus 로고    scopus 로고
    • Immune deviation of 2C transgenic intraepithelial lymphocytes in antigen-bearing hosts
    • Guehler SR, Bluestone JA, Barrett TA. Immune deviation of 2C transgenic intraepithelial lymphocytes in antigen-bearing hosts. J Exp Med 1996;184:493-503.
    • (1996) J Exp Med , vol.184 , pp. 493-503
    • Guehler, S.R.1    Bluestone, J.A.2    Barrett, T.A.3
  • 85
    • 0033545880 scopus 로고    scopus 로고
    • High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8αα and CD8αα T lymphocytes
    • Levelt CN, et al. High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8αα and CD8αα T lymphocytes. Proc Natl Acad Sci USA 1999;96:5628- 5633.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5628-5633
    • Levelt, C.N.1
  • 86
    • 1642313753 scopus 로고    scopus 로고
    • Virus-induced activation of self-specific TCRαβ CD8αα intraepithelial lymphocytes does not abolish their self-tolerance in the intestine
    • Saurer L, Seibold I, Rihs S, Vallan C, Dumrese T, Mueller C. Virus-induced activation of self-specific TCRαβ CD8αα intraepithelial lymphocytes does not abolish their self-tolerance in the intestine. J Immunol 2004;172:4176-4183.
    • (2004) J Immunol , vol.172 , pp. 4176-4183
    • Saurer, L.1    Seibold, I.2    Rihs, S.3    Vallan, C.4    Dumrese, T.5    Mueller, C.6
  • 87
    • 0035451472 scopus 로고    scopus 로고
    • MHC class I allele dosage alters CD8 expression by intestinal intraepithelial lymphocytes
    • Podd BS, Aberg C, Kudla KL, Keene L, Tobias E, Camerini V. MHC class I allele dosage alters CD8 expression by intestinal intraepithelial lymphocytes. J Immunol 2001;167:2561-2568.
    • (2001) J Immunol , vol.167 , pp. 2561-2568
    • Podd, B.S.1    Aberg, C.2    Kudla, K.L.3    Keene, L.4    Tobias, E.5    Camerini, V.6
  • 88
    • 0037128178 scopus 로고    scopus 로고
    • Characterization of T cell differentiation in the murine gut
    • Lambolez F, et al. Characterization of T cell differentiation in the murine gut. J Exp Med 2002;195:437-449.
    • (2002) J Exp Med , vol.195 , pp. 437-449
    • Lambolez, F.1
  • 89
    • 0023008486 scopus 로고
    • Athymic mice express a high level of functional γ-chain but greatly reduced levels of α- and β-chain T-cell receptor messages
    • Yoshikai Y, Reis MD, Mak TW. Athymic mice express a high level of functional γ-chain but greatly reduced levels of α- and β-chain T-cell receptor messages. Nature 1986;324:482-485.
    • (1986) Nature , vol.324 , pp. 482-485
    • Yoshikai, Y.1    Reis, M.D.2    Mak, T.W.3
  • 91
    • 0029118381 scopus 로고
    • Effect of neonatal thymectomy on murine small intestinal intraepithelial lymphocytes expressing T cell receptor αβ and "clonally forbidden Vβs". Adv
    • Lin T, Takimoto H, Matsuzaki G, Nomoto K. Effect of neonatal thymectomy on murine small intestinal intraepithelial lymphocytes expressing T cell receptor αβ and "clonally forbidden Vβs". Adv Exp Med Biol 1995;371A:129-131.
    • (1995) Exp Med Biol , vol.371 A , pp. 129-131
    • Lin, T.1    Takimoto, H.2    Matsuzaki, G.3    Nomoto, K.4
  • 92
    • 0028358824 scopus 로고
    • Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice
    • Rocha B, Vassalli P, Guy-Grand D. Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice. J Exp Med 1994;180:681- 686.
    • (1994) J Exp Med , vol.180 , pp. 681-686
    • Rocha, B.1    Vassalli, P.2    Guy-Grand, D.3
  • 93
    • 0032502836 scopus 로고    scopus 로고
    • Generation of intestinal T cells from progenitors residing in gut cryptopatches
    • Saito H, et al. Generation of intestinal T cells from progenitors residing in gut cryptopatches. Science 1998;280:275-278.
    • (1998) Science , vol.280 , pp. 275-278
    • Saito, H.1
  • 94
    • 0029854809 scopus 로고    scopus 로고
    • + lympho-hemopoietic progenitors develop
    • + lympho-hemopoietic progenitors develop. J Exp Med 1996;184:1449-1459.
    • (1996) J Exp Med , vol.184 , pp. 1449-1459
    • Kanamori, Y.1
  • 95
    • 0034176109 scopus 로고    scopus 로고
    • Role of gut cryptopatches in early extrathymic maturation of intestinal intraepithelial T cells
    • Oida T, et al. Role of gut cryptopatches in early extrathymic maturation of intestinal intraepithelial T cells. J Immunol 2000;164:3616-3626.
    • (2000) J Immunol , vol.164 , pp. 3616-3626
    • Oida, T.1
  • 96
    • 0033636261 scopus 로고    scopus 로고
    • Gut cryptopatches: Direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis
    • Suzuki K, et al. Gut cryptopatches: direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis. Immunity 2000;13:691- 702.
    • (2000) Immunity , vol.13 , pp. 691-702
    • Suzuki, K.1
  • 97
    • 0343183279 scopus 로고    scopus 로고
    • Enterocyte expression of interleukin 7 induces development of γδ T cells and Peyer's patches
    • Laky K, et al. Enterocyte expression of interleukin 7 induces development of γδ T cells and Peyer's patches. J Exp Med 2000;191:1569- 1580.
    • (2000) J Exp Med , vol.191 , pp. 1569-1580
    • Laky, K.1
  • 98
    • 0037415594 scopus 로고    scopus 로고
    • Extrathymic T cell lymphopoiesis: Ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice
    • Guy-Grand D, et al. Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice. J Exp Med 2003;197:333-341.
    • (2003) J Exp Med , vol.197 , pp. 333-341
    • Guy-Grand, D.1
  • 99
    • 13544256622 scopus 로고    scopus 로고
    • Intestinal γδ T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles
    • Nonaka S, et al. Intestinal γδ T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles. J Immunol 2005;174:1906-1912.
    • (2005) J Immunol , vol.174 , pp. 1906-1912
    • Nonaka, S.1
  • 100
    • 33646890073 scopus 로고    scopus 로고
    • T cells in cryptopatch aggregates share TCRγ variable region junctional sequences with γδ T cells in the small intestinal epithelium of mice
    • Podd BS, et al. T cells in cryptopatch aggregates share TCRγ variable region junctional sequences with γδ T cells in the small intestinal epithelium of mice. J Immunol 2006;176:6532-6542.
    • (2006) J Immunol , vol.176 , pp. 6532-6542
    • Podd, B.S.1
  • 101
    • 3042720708 scopus 로고    scopus 로고
    • Thymic origin of intestinal αβ T cells revealed by fate mapping of RORγt+ cells
    • Eberl G, Littman DR. Thymic origin of intestinal αβ T cells revealed by fate mapping of RORγt+ cells. Science 2004;305:248-251.
    • (2004) Science , vol.305 , pp. 248-251
    • Eberl, G.1    Littman, D.R.2
  • 102
    • 20644455777 scopus 로고    scopus 로고
    • Eberl G, Littman DR. Comment on Thymic origin of intestinal αβ T cells revealed by fate mapping of RORγt+ cells. Science 2005;308:1553b.
    • Eberl G, Littman DR. Comment on "Thymic origin of intestinal αβ T cells revealed by fate mapping of RORγt+ cells". Science 2005;308:1553b.
  • 103
    • 29244468256 scopus 로고    scopus 로고
    • The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs
    • Lambolez F, et al. The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs. Nat Immunol 2006;7:76-82.
    • (2006) Nat Immunol , vol.7 , pp. 76-82
    • Lambolez, F.1
  • 104
    • 22344450566 scopus 로고    scopus 로고
    • The timing of TCRaα expression critically influences T cell development and selection
    • Baldwin TA, Sandau MM, Jameson SC, Hogquist KA. The timing of TCRaα expression critically influences T cell development and selection. J Exp Med 2005;202:111-121.
    • (2005) J Exp Med , vol.202 , pp. 111-121
    • Baldwin, T.A.1    Sandau, M.M.2    Jameson, S.C.3    Hogquist, K.A.4
  • 105
    • 0036312122 scopus 로고    scopus 로고
    • Pivotal role of CCL25 (TECK)-CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes
    • Onai N, Kitabatake M, Zhang YY, Ishikawa H, Ishikawa S, Matsushima K. Pivotal role of CCL25 (TECK)-CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes. Int Immunol 2002;14:687-694.
    • (2002) Int Immunol , vol.14 , pp. 687-694
    • Onai, N.1    Kitabatake, M.2    Zhang, Y.Y.3    Ishikawa, H.4    Ishikawa, S.5    Matsushima, K.6
  • 106
    • 0141920522 scopus 로고    scopus 로고
    • Extrathymic TCR gene rearrangement in human small intestine: Identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression
    • Bas A, Hammarstrom SG, Hammarstrom ML. Extrathymic TCR gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression. J Immunol 2003;171:3359-3371.
    • (2003) J Immunol , vol.171 , pp. 3359-3371
    • Bas, A.1    Hammarstrom, S.G.2    Hammarstrom, M.L.3
  • 107
    • 0028925778 scopus 로고
    • Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
    • Cao X, et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 1995;2:223-238.
    • (1995) Immunity , vol.2 , pp. 223-238
    • Cao, X.1
  • 108
    • 0028878330 scopus 로고
    • Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain
    • DiSanto JP, Muller W, Guy-Grand D, Fischer A, Rajewsky K. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc Natl Acad Sci USA 1995;92:377-381.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 377-381
    • DiSanto, J.P.1    Muller, W.2    Guy-Grand, D.3    Fischer, A.4    Rajewsky, K.5
  • 109
    • 0030587133 scopus 로고    scopus 로고
    • Inhibition of γδ T cell development and early thymocyte maturation in IL-7-/- mice
    • Moore TA, von Freeden-Jeffry U, Murray R, Zlotnik A. Inhibition of γδ T cell development and early thymocyte maturation in IL-7-/- mice. J Immunol 1996;157:2366-2373.
    • (1996) J Immunol , vol.157 , pp. 2366-2373
    • Moore, T.A.1    von Freeden-Jeffry, U.2    Murray, R.3    Zlotnik, A.4
  • 110
    • 0029957040 scopus 로고    scopus 로고
    • Interleukin 7 receptor-deficient mice lack γδ T cells
    • Maki K, et al. Interleukin 7 receptor-deficient mice lack γδ T cells. Proc Natl Acad Sci U S A 1996;93:7172-7177.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 7172-7177
    • Maki, K.1
  • 111
    • 0030442579 scopus 로고    scopus 로고
    • The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice
    • Maki K, Sunaga S, Ikuta K. The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice. J Exp Med 1996;184:2423-2427.
    • (1996) J Exp Med , vol.184 , pp. 2423-2427
    • Maki, K.1    Sunaga, S.2    Ikuta, K.3
  • 112
    • 0031051547 scopus 로고    scopus 로고
    • Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain
    • Suzuki H, Duncan GS, Takimoto H, Mak TW. Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain. J Exp Med 1997;185:499-505.
    • (1997) J Exp Med , vol.185 , pp. 499-505
    • Suzuki, H.1    Duncan, G.S.2    Takimoto, H.3    Mak, T.W.4
  • 113
    • 0034610970 scopus 로고    scopus 로고
    • Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
    • Kennedy MK, et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000;191:771- 780.
    • (2000) J Exp Med , vol.191 , pp. 771-780
    • Kennedy, M.K.1
  • 114
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce JP, et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998;9:669-676.
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1
  • 115
    • 0030714613 scopus 로고    scopus 로고
    • Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing γδ T cell receptor in mice
    • Inagaki-Ohara K, Nishimura H, Mitani A, Yoshikai Y. Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing γδ T cell receptor in mice. Eur J Immunol 1997;27:2885-2891.
    • (1997) Eur J Immunol , vol.27 , pp. 2885-2891
    • Inagaki-Ohara, K.1    Nishimura, H.2    Mitani, A.3    Yoshikai, Y.4
  • 116
    • 30044448268 scopus 로고    scopus 로고
    • Interleukin 15 controls the generation of the restricted T cell receptor repertoire of γδ intestinal intraepithelial lymphocytes
    • Zhao H, Nguyen H, Kang J. Interleukin 15 controls the generation of the restricted T cell receptor repertoire of γδ intestinal intraepithelial lymphocytes. Nat Immunol 2005;6:1263-1271.
    • (2005) Nat Immunol , vol.6 , pp. 1263-1271
    • Zhao, H.1    Nguyen, H.2    Kang, J.3
  • 117
    • 33646466776 scopus 로고    scopus 로고
    • MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8αα TCRαβ and TCRγδ intestinal intraepithelial lymphocytes
    • Yu Q, Tang C, Xun S, Yajima T, Takeda K, Yoshikai Y. MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8αα TCRαβ and TCRγδ intestinal intraepithelial lymphocytes. J Immunol 2006;176:6180-6185.
    • (2006) J Immunol , vol.176 , pp. 6180-6185
    • Yu, Q.1    Tang, C.2    Xun, S.3    Yajima, T.4    Takeda, K.5    Yoshikai, Y.6
  • 118
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
    • Cyster JG. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu Rev Immunol 2005;23:127-159.
    • (2005) Annu Rev Immunol , vol.23 , pp. 127-159
    • Cyster, J.G.1
  • 119
    • 0036166387 scopus 로고    scopus 로고
    • Chemokines and the tissue-specific migration of lymphocytes
    • Kunkel EJ, Butcher EC. Chemokines and the tissue-specific migration of lymphocytes. Immunity 2002;16:1-4.
    • (2002) Immunity , vol.16 , pp. 1-4
    • Kunkel, E.J.1    Butcher, E.C.2
  • 120
    • 0033231492 scopus 로고    scopus 로고
    • Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis
    • Zabel BA, et al. Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med 1999;190:1241-1256.
    • (1999) J Exp Med , vol.190 , pp. 1241-1256
    • Zabel, B.A.1
  • 121
    • 0242305118 scopus 로고    scopus 로고
    • Chemokines in lymphocyte trafficking and intestinal immunity
    • Kunkel EJ, Campbell DJ, Butcher EC. Chemokines in lymphocyte trafficking and intestinal immunity. Microcirculation 2003;10:313-323.
    • (2003) Microcirculation , vol.10 , pp. 313-323
    • Kunkel, E.J.1    Campbell, D.J.2    Butcher, E.C.3
  • 122
    • 0034327830 scopus 로고    scopus 로고
    • The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system
    • Papadakis KA, et al. The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. J Immunol 2000;165:5069-5076.
    • (2000) J Immunol , vol.165 , pp. 5069-5076
    • Papadakis, K.A.1
  • 123
    • 0034605043 scopus 로고    scopus 로고
    • Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity
    • Kunkel EJ, et al. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J Exp Med 2000;192:761-768.
    • (2000) J Exp Med , vol.192 , pp. 761-768
    • Kunkel, E.J.1
  • 124
    • 0036802422 scopus 로고    scopus 로고
    • CCL25 mediates the localization of recently activated CD8αβ(+) lymphocytes to the small-intestinal mucosa
    • Svensson M, et al. CCL25 mediates the localization of recently activated CD8αβ(+) lymphocytes to the small-intestinal mucosa. J Clin Invest 2002;110:1113-1121.
    • (2002) J Clin Invest , vol.110 , pp. 1113-1121
    • Svensson, M.1
  • 125
    • 0036910773 scopus 로고    scopus 로고
    • Involvement of CCL25 (TECK) in the generation of the murine small-intestinal CD8αα+CD3+ intraepithelial lymphocyte compartment
    • Marsal J, et al. Involvement of CCL25 (TECK) in the generation of the murine small-intestinal CD8αα+CD3+ intraepithelial lymphocyte compartment. Eur J Immunol 2002;32:3488-3497.
    • (2002) Eur J Immunol , vol.32 , pp. 3488-3497
    • Marsal, J.1
  • 126
    • 0037087478 scopus 로고    scopus 로고
    • A role for CCR9 in T lymphocyte development and migration
    • Uehara S, Grinberg A, Farber JM, Love PE. A role for CCR9 in T lymphocyte development and migration. J Immunol 2002;168:2811-2819.
    • (2002) J Immunol , vol.168 , pp. 2811-2819
    • Uehara, S.1    Grinberg, A.2    Farber, J.M.3    Love, P.E.4
  • 127
    • 0033986966 scopus 로고    scopus 로고
    • The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9
    • Wurbel MA, et al. The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9. Eur J Immunol 2000;30:262-271.
    • (2000) Eur J Immunol , vol.30 , pp. 262-271
    • Wurbel, M.A.1
  • 128
    • 0037382166 scopus 로고    scopus 로고
    • CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells
    • Kunkel EJ, et al. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J Clin Invest 2003;111:1001-1010.
    • (2003) J Clin Invest , vol.111 , pp. 1001-1010
    • Kunkel, E.J.1
  • 129
    • 0346665751 scopus 로고    scopus 로고
    • A common mucosal chemokine (mucosae-associated epithelial chemokine/CCL28) selectively attracts IgA plasmablasts
    • Lazarus NH, Kunkel EJ, Johnston B, Wilson E, Youngman KR, Butcher EC. A common mucosal chemokine (mucosae-associated epithelial chemokine/CCL28) selectively attracts IgA plasmablasts. J Immunol 2003;170:3799-3805.
    • (2003) J Immunol , vol.170 , pp. 3799-3805
    • Lazarus, N.H.1    Kunkel, E.J.2    Johnston, B.3    Wilson, E.4    Youngman, K.R.5    Butcher, E.C.6
  • 130
    • 0034664725 scopus 로고    scopus 로고
    • A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues
    • Pan J, et al. A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues. J Immunol 2000;165:2943-2949.
    • (2000) J Immunol , vol.165 , pp. 2943-2949
    • Pan, J.1
  • 131
    • 0041665003 scopus 로고    scopus 로고
    • CCR5 mediates specific migration of Toxoplasma gondii-primed CD8 lymphocytes to inflammatory intestinal epithelial cells
    • Luangsay S, et al. CCR5 mediates specific migration of Toxoplasma gondii-primed CD8 lymphocytes to inflammatory intestinal epithelial cells. Gastroenterology 2003;125:491-500.
    • (2003) Gastroenterology , vol.125 , pp. 491-500
    • Luangsay, S.1
  • 132
    • 0035166858 scopus 로고    scopus 로고
    • Characterization of epithelial chemoattractants for human intestinal intraepithelial lymphocytes
    • Shibahara T, Wilcox JN, Couse T, Madara JL. Characterization of epithelial chemoattractants for human intestinal intraepithelial lymphocytes. Gastroenterology 2001;120:60-70.
    • (2001) Gastroenterology , vol.120 , pp. 60-70
    • Shibahara, T.1    Wilcox, J.N.2    Couse, T.3    Madara, J.L.4
  • 133
    • 0034001778 scopus 로고    scopus 로고
    • Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation
    • Agace WW, Roberts AI, Wu L, Greineder C, Ebert EC, Parker CM. Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation. Eur J Immunol 2000;30:819-826.
    • (2000) Eur J Immunol , vol.30 , pp. 819-826
    • Agace, W.W.1    Roberts, A.I.2    Wu, L.3    Greineder, C.4    Ebert, E.C.5    Parker, C.M.6
  • 134
    • 17444450861 scopus 로고    scopus 로고
    • Lymphoid precursors in intestinal cryptopatches express CCR6 and undergo dysregulated development in the absence of CCR6
    • Lugering A, Kucharzik T, Soler D, Picarella D, Hudson JT 3rd, Williams IR. Lymphoid precursors in intestinal cryptopatches express CCR6 and undergo dysregulated development in the absence of CCR6. J Immunol 2003;171:2208- 2215.
    • (2003) J Immunol , vol.171 , pp. 2208-2215
    • Lugering, A.1    Kucharzik, T.2    Soler, D.3    Picarella, D.4    Hudson 3rd, J.T.5    Williams, I.R.6
  • 135
    • 0035905398 scopus 로고    scopus 로고
    • CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: Modulation by FTY720
    • Henning G, et al. CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: modulation by FTY720. J Exp Med 2001;194:1875-1881.
    • (2001) J Exp Med , vol.194 , pp. 1875-1881
    • Henning, G.1
  • 136
    • 2942595711 scopus 로고    scopus 로고
    • The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells
    • Kimura T, et al. The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells. Blood 2004;103:4478-4486.
    • (2004) Blood , vol.103 , pp. 4478-4486
    • Kimura, T.1
  • 137
    • 0029665856 scopus 로고    scopus 로고
    • Critical role for β7 integrins in formation of the gut-associated lymphoid tissue
    • Wagner N, et al. Critical role for β7 integrins in formation of the gut-associated lymphoid tissue. Nature 1996;382:366-370.
    • (1996) Nature , vol.382 , pp. 366-370
    • Wagner, N.1
  • 138
    • 0033577577 scopus 로고    scopus 로고
    • The role of β7 integrins in CD8 T cell trafficking during an antiviral immune response
    • Lefrancois L, et al. The role of β7 integrins in CD8 T cell trafficking during an antiviral immune response. J Exp Med 1999;189:1631- 1638.
    • (1999) J Exp Med , vol.189 , pp. 1631-1638
    • Lefrancois, L.1
  • 139
    • 0141449950 scopus 로고    scopus 로고
    • Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): Requirement for GALT dendritic cells and adjuvant
    • Johansson-Lindbom B, Svensson M, Wurbel MA, Malissen B, Marquez G, Agace W. Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant. J Exp Med 2003;198:963-969.
    • (2003) J Exp Med , vol.198 , pp. 963-969
    • Johansson-Lindbom, B.1    Svensson, M.2    Wurbel, M.A.3    Malissen, B.4    Marquez, G.5    Agace, W.6
  • 140
    • 0038264036 scopus 로고    scopus 로고
    • Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
    • Mora JR, et al. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 2003;424:88-93.
    • (2003) Nature , vol.424 , pp. 88-93
    • Mora, J.R.1
  • 141
    • 0036099957 scopus 로고    scopus 로고
    • Intestinal dendritic cells increase T cell expression of α4β7 integrin
    • Stagg AJ, Kamm MA, Knight SC. Intestinal dendritic cells increase T cell expression of α4β7 integrin. Eur J Immunol 2002;32:1445-1454.
    • (2002) Eur J Immunol , vol.32 , pp. 1445-1454
    • Stagg, A.J.1    Kamm, M.A.2    Knight, S.C.3
  • 143
    • 0031278410 scopus 로고    scopus 로고
    • Activation and migration of CD8 T cells in the intestinal mucosa
    • Kim SK, Reed DS, Heath WR, Carbone F, Lefrancois L. Activation and migration of CD8 T cells in the intestinal mucosa. J Immunol 1997;159:4295-4306.
    • (1997) J Immunol , vol.159 , pp. 4295-4306
    • Kim, S.K.1    Reed, D.S.2    Heath, W.R.3    Carbone, F.4    Lefrancois, L.5
  • 144
    • 0027944111 scopus 로고
    • Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin
    • Cepek KL, et al. Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin. Nature 1994;372:190-193.
    • (1994) Nature , vol.372 , pp. 190-193
    • Cepek, K.L.1
  • 145
    • 0033984978 scopus 로고    scopus 로고
    • Adhesion molecules expressed on homing lymphocytes in model intestinal epithelia
    • Shibahara T, Si-Tahar M, Shaw SK, Madara JL. Adhesion molecules expressed on homing lymphocytes in model intestinal epithelia. Gastroenterology 2000;118:289-298.
    • (2000) Gastroenterology , vol.118 , pp. 289-298
    • Shibahara, T.1    Si-Tahar, M.2    Shaw, S.K.3    Madara, J.L.4
  • 146
    • 7244248660 scopus 로고    scopus 로고
    • CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes
    • Ericsson A, Svensson M, Arya A, Agace WW. CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes. Eur J Immunol 2004;34:2720-2729.
    • (2004) Eur J Immunol , vol.34 , pp. 2720-2729
    • Ericsson, A.1    Svensson, M.2    Arya, A.3    Agace, W.W.4
  • 147
    • 19344361971 scopus 로고    scopus 로고
    • TGF-β-dependent CD103 expression by CD8(+) T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host disease
    • El-Asady R, et al. TGF-β-dependent CD103 expression by CD8(+) T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host disease. J Exp Med 2005;201:1647-1657.
    • (2005) J Exp Med , vol.201 , pp. 1647-1657
    • El-Asady, R.1
  • 148
    • 0033151953 scopus 로고    scopus 로고
    • Mucosal T lymphocyte numbers are selectively reduced in integrin αE (CD103)-deficient mice
    • Schon MP, et al. Mucosal T lymphocyte numbers are selectively reduced in integrin αE (CD103)-deficient mice. J Immunol 1999;162:6641-6649.
    • (1999) J Immunol , vol.162 , pp. 6641-6649
    • Schon, M.P.1
  • 149
    • 0033174321 scopus 로고    scopus 로고
    • Integrin α1β1 (VLA-1) mediates adhesion of activated intraepithelial lymphocytes to collagen
    • Roberts AI, Brolin RE, Ebert EC. Integrin α1β1 (VLA-1) mediates adhesion of activated intraepithelial lymphocytes to collagen. Immunology 1999;97:679-685.
    • (1999) Immunology , vol.97 , pp. 679-685
    • Roberts, A.I.1    Brolin, R.E.2    Ebert, E.C.3
  • 150
    • 0030071064 scopus 로고    scopus 로고
    • Human intestinal intraepithelial lymphocytes bind to mucosal mesenchymal cells through VLA4 and CD11α
    • Ebert EC, Roberts AI. Human intestinal intraepithelial lymphocytes bind to mucosal mesenchymal cells through VLA4 and CD11α. Cell Immunol 1996;167:108-114.
    • (1996) Cell Immunol , vol.167 , pp. 108-114
    • Ebert, E.C.1    Roberts, A.I.2
  • 151
    • 0030222766 scopus 로고    scopus 로고
    • β2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment
    • Huleatt JW, Lefrancois L. β2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment. Immunity 1996;5:263-273.
    • (1996) Immunity , vol.5 , pp. 263-273
    • Huleatt, J.W.1    Lefrancois, L.2
  • 152
    • 20844462939 scopus 로고    scopus 로고
    • β1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia
    • Marsal J, Brakebusch C, Bungartz G, Fassler R, Agace WW. β1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia. Eur J Immunol 2005;35:1805-1811.
    • (2005) Eur J Immunol , vol.35 , pp. 1805-1811
    • Marsal, J.1    Brakebusch, C.2    Bungartz, G.3    Fassler, R.4    Agace, W.W.5
  • 153
    • 7044231033 scopus 로고    scopus 로고
    • Biological role of Ep-CAM in the physical interaction between epithelial cells and lymphocytes in intestinal epithelium
    • Nochi T, et al. Biological role of Ep-CAM in the physical interaction between epithelial cells and lymphocytes in intestinal epithelium. Clin Immunol 2004;113:326-339.
    • (2004) Clin Immunol , vol.113 , pp. 326-339
    • Nochi, T.1
  • 156
    • 0037013968 scopus 로고    scopus 로고
    • A unique subset of self-specific intraintestinal T cells maintains gut integrity
    • Poussier P, Ning T, Banerjee D, Julius M. A unique subset of self-specific intraintestinal T cells maintains gut integrity. J Exp Med 2002;195:1491-1497.
    • (2002) J Exp Med , vol.195 , pp. 1491-1497
    • Poussier, P.1    Ning, T.2    Banerjee, D.3    Julius, M.4
  • 157
    • 0034053959 scopus 로고    scopus 로고
    • Intestinal inflammation observed in IL-2R/IL-2 mutant mice is associated with impaired intestinal T lymphopoiesis
    • Poussier P, Ning T, Chen J, Banerjee D, Julius M. Intestinal inflammation observed in IL-2R/IL-2 mutant mice is associated with impaired intestinal T lymphopoiesis. Gastroenterology 2000;118:880-891.
    • (2000) Gastroenterology , vol.118 , pp. 880-891
    • Poussier, P.1    Ning, T.2    Chen, J.3    Banerjee, D.4    Julius, M.5
  • 158
    • 20244373954 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Gastroenterology 2005;128:922-934.
    • (2005) Gastroenterology , vol.128 , pp. 922-934
    • Kai, Y.1
  • 159
    • 0343920681 scopus 로고    scopus 로고
    • Intestinal intraepithelial lymphocytes exert potent protective cytotoxic activity during an acute virus infection
    • Muller S, Buhler-Jungo M, Mueller C. Intestinal intraepithelial lymphocytes exert potent protective cytotoxic activity during an acute virus infection. J Immunol 2000;164:1986-1994.
    • (2000) J Immunol , vol.164 , pp. 1986-1994
    • Muller, S.1    Buhler-Jungo, M.2    Mueller, C.3
  • 160
    • 0032213380 scopus 로고    scopus 로고
    • Gut-derived intraepithelial lymphocytes induce long term immunity against Toxoplasma gondii
    • Lepage AC, Buzoni-Gatel D, Bout DT, Kasper LH. Gut-derived intraepithelial lymphocytes induce long term immunity against Toxoplasma gondii. J Immunol 1998;161:4902-4908.
    • (1998) J Immunol , vol.161 , pp. 4902-4908
    • Lepage, A.C.1    Buzoni-Gatel, D.2    Bout, D.T.3    Kasper, L.H.4
  • 161
    • 0028117098 scopus 로고
    • Modulation of epithelial cell growth by intraepithelial γδ T cells
    • Boismenu R, Havran WL. Modulation of epithelial cell growth by intraepithelial γδ T cells. Science 1994;266:1253-1255.
    • (1994) Science , vol.266 , pp. 1253-1255
    • Boismenu, R.1    Havran, W.L.2
  • 162
    • 0029016752 scopus 로고
    • Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells
    • Komano H, et al. Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells. Proc Natl Acad Sci USA 1995;92:6147-6151.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6147-6151
    • Komano, H.1
  • 163
    • 0032586367 scopus 로고    scopus 로고
    • Physiological roles of γδ T-cell receptor intraepithelial lymphocytes in cytoproliferation and differentiation of mouse intestinal epithelial cells
    • Matsumoto S, et al. Physiological roles of γδ T-cell receptor intraepithelial lymphocytes in cytoproliferation and differentiation of mouse intestinal epithelial cells. Immunology 1999;97:18-25.
    • (1999) Immunology , vol.97 , pp. 18-25
    • Matsumoto, S.1
  • 164
    • 3142686026 scopus 로고    scopus 로고
    • Mucosal T cells bearing TCRγδ play a protective role in intestinal inflammation
    • Inagaki-Ohara K, et al. Mucosal T cells bearing TCRγδ play a protective role in intestinal inflammation. J Immunol 2004;173:1390-1398.
    • (2004) J Immunol , vol.173 , pp. 1390-1398
    • Inagaki-Ohara, K.1
  • 165
    • 0035964092 scopus 로고    scopus 로고
    • Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile
    • Fahrer AM, et al. Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile. Proc Natl Acad Sci USA 2001;98:10261-10266.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10261-10266
    • Fahrer, A.M.1
  • 166
    • 0037331535 scopus 로고    scopus 로고
    • Transforming growth factor-β mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells
    • Beck PL, Rosenberg IM, Xavier RJ, Koh T, Wong JF, Podolsky DK. Transforming growth factor-β mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells. Am J Pathol 2003;162:597-608.
    • (2003) Am J Pathol , vol.162 , pp. 597-608
    • Beck, P.L.1    Rosenberg, I.M.2    Xavier, R.J.3    Koh, T.4    Wong, J.F.5    Podolsky, D.K.6
  • 168
    • 0029862501 scopus 로고    scopus 로고
    • + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium
    • + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium. Proc Natl Acad Sci U S A 1996;93:11774-11779.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11774-11779
    • Roberts, S.J.1
  • 170
  • 171
    • 0029975876 scopus 로고    scopus 로고
    • Cytokine imbalance and autoantibody production in T cell receptor-α mutant mice with inflammatory bowel disease
    • Mizoguchi A, et al. Cytokine imbalance and autoantibody production in T cell receptor-α mutant mice with inflammatory bowel disease. J Exp Med 1996;183:847-856.
    • (1996) J Exp Med , vol.183 , pp. 847-856
    • Mizoguchi, A.1
  • 172
    • 0031004877 scopus 로고    scopus 로고
    • + T-cell population mediates development of inflammatory bowel disease in T-cell receptor α chain-deficient mice
    • + T-cell population mediates development of inflammatory bowel disease in T-cell receptor α chain-deficient mice. Gastroenterology 1997;112:1876-1886.
    • (1997) Gastroenterology , vol.112 , pp. 1876-1886
    • Takahashi, I.1    Kiyono, H.2    Hamada, S.3
  • 173
    • 0026562047 scopus 로고
    • + T cells provide B cell help
    • + T cells provide B cell help. J Exp Med 1992;175:695-707.
    • (1992) J Exp Med , vol.175 , pp. 695-707
    • Fujihashi, K.1
  • 175
    • 0029994954 scopus 로고    scopus 로고
    • γ/δ T cell-deficient mice have impaired mucosal immunoglobulin A responses
    • Fujihashi K, et al. γ/δ T cell-deficient mice have impaired mucosal immunoglobulin A responses. J Exp Med 1996;183:1929-1935.
    • (1996) J Exp Med , vol.183 , pp. 1929-1935
    • Fujihashi, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.