CD8β endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56lck complexes

Journal of Experimental Medicine

Volumn 194, Issue 10, 2001, Pages 1485-1495

  Arcaro, Alexandre ^a   Grégoire, Claude ^b   Bakker, Talitha R ^c   Baldi, Lucia ^d   Jordan, Martin ^d   Goffin, Laurence ^a   Boucheron, Nicole ^a   Wurm, Florian ^d   Van Der Merwe, P Anton ^c   Malissen, Bernard ^b   Luescher, Immanuel F ^a,e  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b INSERM   (France)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d EPFL   (Switzerland)

^e LUDWIG INSTITUTE FOR CANCER RESEARCH   (Switzerland)

Author keywords

Cytotoxicity; Phosphorylation; Plasmon resonance; Protein tyrosine kinase; T lymphocytes

Indexed keywords

4 AZIDOBENZOIC ACID; CD3 ANTIGEN; CD8 ANTIGEN; CD8ALPHABETA ANTIGEN; CD8BETA ANTIGEN; CELL PROTEIN; PEPTIDE DERIVATIVE; PROTEIN P56; PROTEIN RAFT; PROTOZOAL PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; CALCIUM; CD3 ANTIGEN, ZETA CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN KINASE LCK;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CONTROLLED STUDY; CYTOPLASM; GENETIC TRANSFECTION; HYBRIDOMA; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMBRANE POTENTIAL; NONHUMAN; PHOSPHORYLATION; PHOTOAFFINITY LABELING; PLASMODIUM BERGHEI; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR BINDING; SPOROZOITE; T LYMPHOCYTE; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE; CHO CELL; HAMSTER; METABOLISM; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD3; ANTIGENS, CD8; CALCIUM; CHO CELLS; CRICETINAE; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE MICRODOMAINS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL;

EID: 0035914485     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.10.1485     Document Type: Article

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