Gut-derived intraepithelial lymphocytes induce long term immunity against Toxoplasma gondii

Journal of Immunology

Volumn 161, Issue 9, 1998, Pages 4902-4908

  Lepage, Anne C ^a   Buzoni Gatel, Dominique ^b   Bout, Daniel T ^b   Kasper, Lloyd H ^a,c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITÉ DE TOURS   (France)

^c DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; T LYMPHOCYTE RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HOST RESISTANCE; IMMUNOREGULATION; INTESTINE EPITHELIUM CELL; LYMPHOCYTE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ADOPTIVE TRANSFER; ANIMALS; FEMALE; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; PEYER'S PATCHES; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES; TIME FACTORS; TOXOPLASMA;

EID: 0032213380     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Guy-Grand, D., and P. Vassalli. 1993. Gut intraepithelial T lymphocytes. Curr. Opin. Immunol. 5:247.
2. Guy-Grand, D., B. Rocha, N. Cerf-Bensussan, and P. Vassalli. 1992. Immunité et tube digestif. In Les Lymphocytes T de la Muqueuse Intestinale, Chapt. 3. J. P. Galmiche, J. P. Revillard, and M. Teule-Espié, eds. John Libbey Eurotext, Paris, p. 25.
3. Lefrancois, L., B. Fuller, J. W. Huleatt, S. Olson, and L. Puddington. 1997. On the front lines, intraepithelial lymphocytes as primary effectors of intestinal immunity. Springer Semin. Immunopathol. 18:463.
4. Neutra, M. R., E. Pringault, and J. P. Kraehenbuhl. 1996. Antigen sampling across epithelial barriers and induction of mucosal immune responses. Annu. Rev. Immunol. 14:275.
5. Mayer, L. 1994. Lymphoepithelial interactions: activation of T-cells by epithelial cells. Mucosal Immunol. Update 2:1.
6. + murine intestinal intraepithelial lymphocytes can mediate perforin-based cytotoxicity, whereas both subsets are active in Fas-based cytotoxicity. J. Immunol. 156:35.
7. Guy-Grand, D., M. Malassis-Seris, C. Briottet, and P. Vassalli. 1991. Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally: correlation between functional assays, presence of perform and granzyme transcripts, and cytoplasmic granules. J. Exp. Med. 173:1549.
8. Yamamoto, M., K. Fujihashi, K. W. Beagley, J. R. McGhee, and H. Kiyono. 1993. Cytokine synthesis by intestinal intraepithelial lymphocytes. J. Immunol. 150:106.
9. Buzoni-Gatel, D., A. C. Lepage, I. H. Dimier-Poisson, D. T. Bout, and L. H. Kasper. 1997. Adoptive transfer of gut intraepithelial lymphocytes protects against murine infection with Toxoplasma gondii. J. Immunol. 158:5883.
10. + gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes. J. Immunol. 153:4593.
11. Suzuki, Y., M. A. Orellana, R. Schreiber, and J. S. Remington. 1988. Interferon-γ: the major mediator of resistance against Toxoplasma gondii. Science 240: 516.
12. Suzuki, Y., F. C. Conley, and J. S. Remington. 1990. Treatment of toxoplasmic encephalitis in mice with recombinant γ interferon. Infect. Immun. 58:3050.
13. + T cell clone protects against acute Toxoplasma gondii infection in mice. J. Immunol. 152:1855.
14. + cytotoxic lymphocytes lyse Toxoplasma gondii-infected cells. J. Immunol. 147: 3955.
15. Lefrancois, L. 1987. Carbohydrate differentiation antigens of murine T cells: expression on intestinal lymphocytes and intestinal epithelium. J. Immunol. 138: 3375.
16. + memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J. Immunol. 148:324.
17. + T cells differing in CD45R expression. J. Immunol. 149:2300.
18. Walker, P. R., T. Ohteki, J. A. Lopez, H. R. MacDonald, and J. L. Maryanski. 1995. Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response. J. Immunol. 155:3443.
19. + T cells. J. Immunol. 155:1873.
20. Laugier, M., and M. Quilici 1970. Interet expérimental d'une souche de Toxoplasma gondii peu pathogène pour la souris. Ann. Parasitol. Hum. Comp. 45:389.
21. Guy-Grand, D., C. Griscelli, and P. Vassalli. 1978. The mouse gut T lymphocyte, a novel type of T cell. Nature, origin and traffic in mice in normal and graft-versus-host conditions. J. Exp. Med. 148:1661.
22. + T cell-dependent interferon-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J. Exp. Med. 184:597.
23. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60.
24. Kim, S. K., D. S. Reed, W. R. Heath, F. Carbone, and L. Lefrancois. 1997. Activation and migration of CD8 T cells in the intestinal mucosa. J. Immunol. 159:4295.
25. Hanninen, A., I. Jaakkola, M. Salmi, O. Simell, and S. Jalkanan. 1997. Ly-6C regulates endothelial adhesion and homing of CD8(+) T cells by activating integrin-dependent adhesion pathways. Proc. Natl. Acad. Sci. USA 94:6898.
26. Nathan, C. F., H. W. Murray, M. E. Weibe, and B. Y. Rubin. 1983. Identification of interferon γ is the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J. Exp. Med. 158:670.
27. Adams, L. B., J. B. Hibbs, R. D. Taintor, and J. L. Krahenbuhl. 1990. Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii: role for synthesis of inorganic nitrogen oxides from L-arginine. J. Immunol. 144:2725.
28. Murray, H. W., G. L. Spitalny, and C. F. Nathan. 1985. Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-γ. J. Immunol. 134: 1619.
29. Khan, I. A., J. D. Schwartzman, T. Matsuura, and L. H. Kasper. 1997. A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice. Proc. Natl. Acad. Sci. USA 94:13955.
30. + T cell. Immun. Today 15:107.
31. Doukas, J., and J. S. Pober. 1990. IFN-γ enhances endothelial activation induced by tumor necrosis factor but not IL-1. J. Immunol. 145:1727.
32. Sydora, B. C., R. Aranda, S. Tangri, H. R. Holocombe, V. Camerini, A. R. Castano, J. E. Miller, S. Cardell, W. D. Huse, P. A. Peterson, et al. 1996. Lymphocyte-epithelial cross-talk in the intestine: do nonclassical class I molecules have big part in the dialogue? In Essentials of Mucosal Immunology. M. R. Kagnoff and H. Kiyono, eds. Academic Press, San Diego, p. 205.
33. Mayer, L., X. Y. Yio, A. Panja, and N. Campell. 1996. Nonprofessional antigen presentation : new rules and regulations. In Essentials of Mucosal Immunology. M. R. Kagnoff and H. Kiyono, eds. Academic Press, San Diego, p. 55.
34. Sayles, P. C., A. L. Rakhmilevich, and L. L. Johnson. 1995. γδ T cells and acute primary Toxoplasma gondii infection in mice. J. Infect. Dis. 171:249.
35. Kasper, L. H., T. Matsuura, S. Fonseka, J. Arruda, J. Y. Channon and I. A. Khan. Induction of gd T cells durind acute murine infection with T. gondii. J. Immunol. 157:5221.
36. Mengel, J., F. Cardillo, L. S. Aroeira, O. Williams, M. Russo, and N. M. Vaz. 1995. Anti-γδ T cell antibody blocks the induction of oral tolerance to ovalbumin in mice. Immunol. Lett. 48:97.
37. + T cells provide B cell help. J. Exp. Med. 175:695.
38. + cells produce IFN-γ and IL-5. J. Immunol. 147:3736.
39. + T cells in the normal gut mucosa. J. Immunol. 160:754.
40. Komano, I., Y. Fujiura, M. Kawaguchi, S. Matsumoto, Y. Hashumoto, S. Obana, P. Mombaerts, S. Tonegawa, H. Yamamoto, S. Itohara, et al. 1995. Homeostatic regulation of intestinal epithelia by intraepithelila γδ T cells. Proc. Natl. Acad. Sci. USA 92:6147.
41. + phenotypes from orally immunized mice provide Th2-like function for B cell responses. J. Immunol. 152:6681.
42. Fujihashi, K., J. R. Mcghee, M. N. Kweon, M. D. Cooper, S. Tonegawa, I. Takahashi, T. Hiroi, J. Mestecky, and H. Kiyono. 1996. γδ cell-deficient mice have impaired mucosal IgA responses. J. Exp. Med. 183:1929.
43. Boismenu, R., L. Feng, Y. Y. Xia, J. C. C. Chang, and W. L. Havran. 1996. Chemokine expression by intraepithelial γδ T cells: implications for the recruitment of inflammatory cells to damaged epithelial. J. Immunol. 157:985.
44. Harrison, L. C., M. Dempsey-Collier, D. R. Kramer, and K. Takahashi. 1996. Aerosol insulin induces regulatory CD8 γδ T cells that prevent murine insulin-dependent diabetes. J. Exp. Med. 184:2167.
45. + cells suppress experimental autoimmune uveitis. Eur. J. Immunol. 26: 2140.
46. Roberts, S., A. Smith, A. B. West, L. Wen, R. C. Findly, M. J. Owen, and A. C. Hayday. 1996. T-cell α-β and γ-δ deficient mice display abnormal but distinct phenotype toward a natural, widespread infection of the intestinal epithelium. Proc. Natl. Acad. Sci. USA 93:11774.
47. Miller, A., O. Lider, A. B. Roberts, M. B. Sporn, and H. L. Weiner. 1992. Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of TGF-β following antigen specific triggering. Proc. Natl. Acad. Sci. USA 89:421.
48. Teitelbaum, D. H., B. Neideck, J. Lee, and R. B. Merion. 1995. Inhibitory activity of intestinal intraepithelial lymphocytes. Surgery 118:378.
49. Teitelbaum, D. H., B. C. Reyes, R. B. Merion, and R. L. Mosley. 1996. Intestinal intraepithelial lymphocytes: identification of an inhibitory subpopulation. J. Surg. Res. 63:123.