-
1
-
-
13844275788
-
Prions, cytokines, and chemokines: A meeting in lymphoid organs
-
Aguzzi A, Heikenwalder M (2005) Prions, cytokines, and chemokines: a meeting in lymphoid organs. Immunity 22:145-154.
-
(2005)
Immunity
, vol.22
, pp. 145-154
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
2
-
-
0842281643
-
Mammalian prion biology: One century of evolving concepts
-
Aguzzi A, Polymenidou M (2004) Mammalian prion biology: one century of evolving concepts. Cell 116:313-327.
-
(2004)
Cell
, vol.116
, pp. 313-327
-
-
Aguzzi, A.1
Polymenidou, M.2
-
3
-
-
4544224048
-
Antiprion immunotherapy: To suppress or to stimulate?
-
Aguzzi A, Sigurdson CJ (2004) Antiprion immunotherapy: to suppress or to stimulate? Nat Rev Immunol 4:725-736.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 725-736
-
-
Aguzzi, A.1
Sigurdson, C.J.2
-
4
-
-
0036798718
-
Phenotyping of protein-prion (PrPsc)-accumulating cells in lymphoid and neural tissues of naturally scrapie-affected sheep by double-labeling immunohistochemistry
-
Andréoletti O, Berthon P, Levavasseur E, Marc D, Lantier F, Monks E, Elsen JM, Schelcher F (2002a) Phenotyping of protein-prion (PrPsc)-accumulating cells in lymphoid and neural tissues of naturally scrapie-affected sheep by double-labeling immunohistochemistry. J Histochem Cytochem 50:1357-1370.
-
(2002)
J Histochem Cytochem
, vol.50
, pp. 1357-1370
-
-
Andréoletti, O.1
Berthon, P.2
Levavasseur, E.3
Marc, D.4
Lantier, F.5
Monks, E.6
Elsen, J.M.7
Schelcher, F.8
-
5
-
-
0345701515
-
Astrocytes accumulate 4-hydroxynonenal adducts in murine scrapie and human Creutzfeldt-Jakob disease
-
Andréoletti O, Levavasseur E, Uro-Coste E, Tabouret G, Sarradin P, Delisle MB, Berthon P, Salvayre R, Schelcher F, Negre-Salvayre A (2002b) Astrocytes accumulate 4-hydroxynonenal adducts in murine scrapie and human Creutzfeldt-Jakob disease. Neurobiol Dis 11:386-393.
-
(2002)
Neurobiol Dis
, vol.11
, pp. 386-393
-
-
Andréoletti, O.1
Levavasseur, E.2
Uro-Coste, E.3
Tabouret, G.4
Sarradin, P.5
Delisle, M.B.6
Berthon, P.7
Salvayre, R.8
Schelcher, F.9
Negre-Salvayre, A.10
-
6
-
-
0037457875
-
Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease
-
Baker CA, Manuelidis L (2003) Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease. Proc Natl Acad Sci USA 100:675-679.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 675-679
-
-
Baker, C.A.1
Manuelidis, L.2
-
7
-
-
0345188622
-
Microglial activation varies in different models of Creutzfeldt-Jakob disease
-
Baker CA, Lu ZY, Zaitsev I, Manuelidis L (1999) Microglial activation varies in different models of Creutzfeldt-Jakob disease. J Virol 73:5089-5097.
-
(1999)
J Virol
, vol.73
, pp. 5089-5097
-
-
Baker, C.A.1
Lu, Z.Y.2
Zaitsev, I.3
Manuelidis, L.4
-
8
-
-
0036838213
-
Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles
-
Baker CA, Martin D, Manuelidis L (2002) Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles. J Virol 76:10905-10913.
-
(2002)
J Virol
, vol.76
, pp. 10905-10913
-
-
Baker, C.A.1
Martin, D.2
Manuelidis, L.3
-
9
-
-
0034068675
-
Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis
-
Beringue V, Demoy M, Lasmezas CI, Gouritin B, Weingarten C, Deslys JP, Andreux JP, Couvreur P, Dormont D (2000a) Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis. J Pathol 190:495-502.
-
(2000)
J Pathol
, vol.190
, pp. 495-502
-
-
Beringue, V.1
Demoy, M.2
Lasmezas, C.I.3
Gouritin, B.4
Weingarten, C.5
Deslys, J.P.6
Andreux, J.P.7
Couvreur, P.8
Dormont, D.9
-
10
-
-
0034044948
-
Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent
-
Beringue V, Adjou KT, Lamoury F, Maignien T, Deslys JP, Race R, Dormont D (2000b) Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent. J Virol 74:5432-5440.
-
(2000)
J Virol
, vol.74
, pp. 5432-5440
-
-
Beringue, V.1
Adjou, K.T.2
Lamoury, F.3
Maignien, T.4
Deslys, J.P.5
Race, R.6
Dormont, D.7
-
11
-
-
0038186806
-
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain
-
Blättler T, Brandner S, Raeber AJ, Klein MA, Voigtlander T, Weissmann C, Aguzzi A (1997) PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain. Nature 389:69-73.
-
(1997)
Nature
, vol.389
, pp. 69-73
-
-
Blättler, T.1
Brandner, S.2
Raeber, A.J.3
Klein, M.A.4
Voigtlander, T.5
Weissmann, C.6
Aguzzi, A.7
-
12
-
-
0026681218
-
An immortalized cell line expresses properties of activated microglial cells
-
Bocchini V, Mazzolla R, Barluzzi R, Blasi E, Sick P, Kettenmann H (1992) An immortalized cell line expresses properties of activated microglial cells. J Neurosci Res 31:616-621.
-
(1992)
J Neurosci Res
, vol.31
, pp. 616-621
-
-
Bocchini, V.1
Mazzolla, R.2
Barluzzi, R.3
Blasi, E.4
Sick, P.5
Kettenmann, H.6
-
13
-
-
0031963428
-
Identification of the end stage of scrapie using infected neural grafts
-
Brandner S, Isenmann S, Kuhne G, Aguzzi A (1998) Identification of the end stage of scrapie using infected neural grafts. Brain Pathol 8:19-27.
-
(1998)
Brain Pathol
, vol.8
, pp. 19-27
-
-
Brandner, S.1
Isenmann, S.2
Kuhne, G.3
Aguzzi, A.4
-
14
-
-
0032746253
-
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
-
Brown KL, Stewart K, Ritchie DL, Mabbott NA, Williams A, Fraser H, Morrison WI, Bruce ME (1999) Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Nat Med 5:1308-1312.
-
(1999)
Nat Med
, vol.5
, pp. 1308-1312
-
-
Brown, K.L.1
Stewart, K.2
Ritchie, D.L.3
Mabbott, N.A.4
Williams, A.5
Fraser, H.6
Morrison, W.I.7
Bruce, M.E.8
-
15
-
-
0029042821
-
MRI assessment of the blood-brain barrier in a hamster model of scrapie
-
Chung YL, Williams A, Beech JS, Williams SC, Bell JD, Cox IJ, Hope J (1995) MRI assessment of the blood-brain barrier in a hamster model of scrapie. Neurodegeneration 4:203-207.
-
(1995)
Neurodegeneration
, vol.4
, pp. 203-207
-
-
Chung, Y.L.1
Williams, A.2
Beech, J.S.3
Williams, S.C.4
Bell, J.D.5
Cox, I.J.6
Hope, J.7
-
16
-
-
0035044016
-
Generation and analysis of mice lacking the chemokine fractalkine
-
Cook DN, Chen SC, Sullivan LM, Manfra DJ, Wiekowski MT, Prosser DM, Vassileva G, Lira SA (2001) Generation and analysis of mice lacking the chemokine fractalkine. Mol Cell Biol 21:3159-3165.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3159-3165
-
-
Cook, D.N.1
Chen, S.C.2
Sullivan, L.M.3
Manfra, D.J.4
Wiekowski, M.T.5
Prosser, D.M.6
Vassileva, G.7
Lira, S.A.8
-
17
-
-
0032571330
-
Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts
-
Dandoy-Dron F, Guillo F, Benboudjema L, Deslys JP, Lasmezas C, Dormont D, Tovey MG, Dron M (1998) Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J Biol Chem 273:7691-7697.
-
(1998)
J Biol Chem
, vol.273
, pp. 7691-7697
-
-
Dandoy-Dron, F.1
Guillo, F.2
Benboudjema, L.3
Deslys, J.P.4
Lasmezas, C.5
Dormont, D.6
Tovey, M.G.7
Dron, M.8
-
18
-
-
33749258893
-
Bone marrow-derived microglia significantly contribute to the pathology following Streptococcus pneumoniae meningitis in mice
-
Djukic M, Mildner A, Schmidt H, Czesnik D, Brück W, Priller J, Nau R, Prinz M (2006) Bone marrow-derived microglia significantly contribute to the pathology following Streptococcus pneumoniae meningitis in mice. Brain 129:2394-2403.
-
(2006)
Brain
, vol.129
, pp. 2394-2403
-
-
Djukic, M.1
Mildner, A.2
Schmidt, H.3
Czesnik, D.4
Brück, W.5
Priller, J.6
Nau, R.7
Prinz, M.8
-
19
-
-
20744448499
-
Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies
-
Donofrio G, Heppner FL, Polymenidou M, Musahl C, Aguzzi A (2005) Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. J Virol 79:8330-8338.
-
(2005)
J Virol
, vol.79
, pp. 8330-8338
-
-
Donofrio, G.1
Heppner, F.L.2
Polymenidou, M.3
Musahl, C.4
Aguzzi, A.5
-
20
-
-
0023243247
-
No evidence for involvement of plasma proteins or blood-borne cells in amyloid plaque formation in scrapie-affected mice. An immunohistoperoxidase study
-
Eikelenboom P, Scott JR, McBride PA, Rozemuller JM, Bruce ME, Fraser H (1987) No evidence for involvement of plasma proteins or blood-borne cells in amyloid plaque formation in scrapie-affected mice. An immunohistoperoxidase study. Virchows Arch B Cell Pathol Incl Mol Pathol 53:251-256.
-
(1987)
Virchows Arch B Cell Pathol Incl Mol Pathol
, vol.53
, pp. 251-256
-
-
Eikelenboom, P.1
Scott, J.R.2
McBride, P.A.3
Rozemuller, J.M.4
Bruce, M.E.5
Fraser, H.6
-
21
-
-
0036186839
-
Macrophage and microglial cell immunoreactivity for PrP(c) in a random post-mortem population
-
Esiri MM, Carter J, Ironside JW (2002) Macrophage and microglial cell immunoreactivity for PrP(c) in a random post-mortem population. Neuropathol Appl Neurobiol 28:79-82.
-
(2002)
Neuropathol Appl Neurobiol
, vol.28
, pp. 79-82
-
-
Esiri, M.M.1
Carter, J.2
Ironside, J.W.3
-
22
-
-
0030011664
-
MR imaging of Creutzfeldt-Jakob disease
-
Finkenstaedt M, Szudra A, Zerr I, Poser S, Hise JH, Stoebner JM, Weber T (1996) MR imaging of Creutzfeldt-Jakob disease. Radiology 199:793-798.
-
(1996)
Radiology
, vol.199
, pp. 793-798
-
-
Finkenstaedt, M.1
Szudra, A.2
Zerr, I.3
Poser, S.4
Hise, J.H.5
Stoebner, J.M.6
Weber, T.7
-
23
-
-
0029863648
-
Prion protein (PrP) with aminoproximal deletions restoring susceptibility of PrP knockout mice to scrapie
-
Fischer M, Rulicke T, Raeber A, Sailer A, Moser M, Oesch B, Brandner S, Aguzzi A, Weissmann C (1996) Prion protein (PrP) with aminoproximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J 15:1255-1264.
-
(1996)
EMBO J
, vol.15
, pp. 1255-1264
-
-
Fischer, M.1
Rulicke, T.2
Raeber, A.3
Sailer, A.4
Moser, M.5
Oesch, B.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
24
-
-
0034707048
-
Binding of disease-associated prion protein to plasminogen
-
Fischer MB, Roeckl C, Parizek P, Schwarz HP, Aguzzi A (2000) Binding of disease-associated prion protein to plasminogen. Nature 408:479- 483.
-
(2000)
Nature
, vol.408
, pp. 479-483
-
-
Fischer, M.B.1
Roeckl, C.2
Parizek, P.3
Schwarz, H.P.4
Aguzzi, A.5
-
25
-
-
0029758220
-
Replication of scrapie in spleens of SCID mice follows reconstitution with wild type mouse bone marrow
-
Fraser H, Brown KL, Stewart K, McConnell I, McBride P, Williams A (1996) Replication of scrapie in spleens of SCID mice follows reconstitution with wild type mouse bone marrow. J Gen Virol 77:1935-1940.
-
(1996)
J Gen Virol
, vol.77
, pp. 1935-1940
-
-
Fraser, H.1
Brown, K.L.2
Stewart, K.3
McConnell, I.4
McBride, P.5
Williams, A.6
-
26
-
-
0034891027
-
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion
-
Glatzel M, Heppner FL, Albers KM, Aguzzi A (2001) Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron 31:25-34.
-
(2001)
Neuron
, vol.31
, pp. 25-34
-
-
Glatzel, M.1
Heppner, F.L.2
Albers, K.M.3
Aguzzi, A.4
-
27
-
-
14744289958
-
Phenotype of disease-associated PrP accumulation in the brain of bovine spongiform encephalopathy experimentally infected sheep
-
González L, Martin S, Houston FE, Hunter N, Reid HW, Bellworthy SJ, Jeffrey M (2005) Phenotype of disease-associated PrP accumulation in the brain of bovine spongiform encephalopathy experimentally infected sheep. J Gen Virol 86:827-838.
-
(2005)
J Gen Virol
, vol.86
, pp. 827-838
-
-
González, L.1
Martin, S.2
Houston, F.E.3
Hunter, N.4
Reid, H.W.5
Bellworthy, S.J.6
Jeffrey, M.7
-
28
-
-
0028220907
-
Relationship of microglia and scrapie amyloid-immunoreactive plaques in kuru, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome
-
(Berl)
-
Guiroy DC, Wakayama I, Liberski PP, Gajdusek DC (1994) Relationship of microglia and scrapie amyloid-immunoreactive plaques in kuru, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome. Acta Neuropathol (Berl) 87:526-530.
-
(1994)
Acta Neuropathol
, vol.87
, pp. 526-530
-
-
Guiroy, D.C.1
Wakayama, I.2
Liberski, P.P.3
Gajdusek, D.C.4
-
30
-
-
0035812752
-
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
-
Heppner FL, Musahl C, Arrighi I, Klein MA, Rulicke T, Oesch B, Zinkernagel RM, Kalinke U, Aguzzi A (2001) Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294:178-182.
-
(2001)
Science
, vol.294
, pp. 178-182
-
-
Heppner, F.L.1
Musahl, C.2
Arrighi, I.3
Klein, M.A.4
Rulicke, T.5
Oesch, B.6
Zinkernagel, R.M.7
Kalinke, U.8
Aguzzi, A.9
-
31
-
-
20044376483
-
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
-
Heppner FL, Greter M, Marino D, Falsig J, Raivich G, Hovelmayer N, Waisman A, Rulicke T, Prinz M, Priller J, Becher B, Aguzzi A (2005) Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med 11:146-152.
-
(2005)
Nat Med
, vol.11
, pp. 146-152
-
-
Heppner, F.L.1
Greter, M.2
Marino, D.3
Falsig, J.4
Raivich, G.5
Hovelmayer, N.6
Waisman, A.7
Rulicke, T.8
Prinz, M.9
Priller, J.10
Becher, B.11
Aguzzi, A.12
-
32
-
-
0023949553
-
Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
-
Hickey WF, Kimura H (1988) Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239:290-292.
-
(1988)
Science
, vol.239
, pp. 290-292
-
-
Hickey, W.F.1
Kimura, H.2
-
33
-
-
0037085719
-
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS
-
Hughes PM, Botham MS, Frentzel S, Mir A, Perry VH (2002) Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Glia 37:314-327.
-
(2002)
Glia
, vol.37
, pp. 314-327
-
-
Hughes, P.M.1
Botham, M.S.2
Frentzel, S.3
Mir, A.4
Perry, V.H.5
-
34
-
-
0032424914
-
Stereological analysis of astrocyte and microglia in aging mouse hippocampus
-
Long JM, Kalehua AN, Muth NJ, Calhoun ME, Jucker M, Hengemihle JM, Ingram DK, Mouton PR (1998) Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiol Aging 19:497-503.
-
(1998)
Neurobiol Aging
, vol.19
, pp. 497-503
-
-
Long, J.M.1
Kalehua, A.N.2
Muth, N.J.3
Calhoun, M.E.4
Jucker, M.5
Hengemihle, J.M.6
Ingram, D.K.7
Mouton, P.R.8
-
35
-
-
0034953560
-
Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells
-
Kaeser PS, Klein MA, Schwarz P, Aguzzi A (2001) Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells. J Virol 75:7097-7106.
-
(2001)
J Virol
, vol.75
, pp. 7097-7106
-
-
Kaeser, P.S.1
Klein, M.A.2
Schwarz, P.3
Aguzzi, A.4
-
36
-
-
0025983158
-
Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease
-
Kitamoto T, Muramoto T, Mohri S, Doh-Ura K, Tateishi J (1991) Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J Virol 65:6292-6295.
-
(1991)
J Virol
, vol.65
, pp. 6292-6295
-
-
Kitamoto, T.1
Muramoto, T.2
Mohri, S.3
Doh-Ura, K.4
Tateishi, J.5
-
37
-
-
0037022288
-
Betaamyloid precursor protein transgenic mice that harbor diffuse a beta deposits but do not form plaques show increased ischemic vulnerability: Role of inflammation
-
Koistinaho M, Kettunen MI, Goldsteins G, Keinanen R, Salminen A, Ort M, Bures J, Liu D, Kauppinen RA, Higgins LS, Koistinaho J (2002) Betaamyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation. Proc Natl Acad Sci USA 99:1610-1615.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1610-1615
-
-
Koistinaho, M.1
Kettunen, M.I.2
Goldsteins, G.3
Keinanen, R.4
Salminen, A.5
Ort, M.6
Bures, J.7
Liu, D.8
Kauppinen, R.A.9
Higgins, L.S.10
Koistinaho, J.11
-
38
-
-
21944457972
-
Bone marrow-derived microglia contribute to the neuroinflammatory response and express iNOS in the MPTP mouse model of Parkinson's disease
-
Kokovay E, Cunningham LA (2005) Bone marrow-derived microglia contribute to the neuroinflammatory response and express iNOS in the MPTP mouse model of Parkinson's disease. Neurobiol Dis 19:471-478.
-
(2005)
Neurobiol Dis
, vol.19
, pp. 471-478
-
-
Kokovay, E.1
Cunningham, L.A.2
-
39
-
-
11144231706
-
Subcellular localization of disease-associated prion protein in the human brain
-
Kovács GG, Preusser M, Strohschneider M, Budka H (2005) Subcellular localization of disease-associated prion protein in the human brain. Am J Pathol 166:287-294.
-
(2005)
Am J Pathol
, vol.166
, pp. 287-294
-
-
Kovács, G.G.1
Preusser, M.2
Strohschneider, M.3
Budka, H.4
-
40
-
-
0030222037
-
Microglia: A sensor for pathological events in the CNS
-
Kreutzberg GW (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
-
(1996)
Trends Neurosci
, vol.19
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
41
-
-
0027343511
-
Bone marrow derived elements and resident microglia in brain inflammation
-
Lassmann H, Schmied M, Vass K, Hickey WF (1993) Bone marrow derived elements and resident microglia in brain inflammation. Glia 7:19-24.
-
(1993)
Glia
, vol.7
, pp. 19-24
-
-
Lassmann, H.1
Schmied, M.2
Vass, K.3
Hickey, W.F.4
-
42
-
-
10344247675
-
The expression of RANTES and chemokine receptors in the brains of scrapie-infected mice
-
Lee HP, Jun YC, Choi JK, Kim JI, Carp RI, Kim YS (2005) The expression of RANTES and chemokine receptors in the brains of scrapie-infected mice. J Neuroimmunol 158:26-33.
-
(2005)
J Neuroimmunol
, vol.158
, pp. 26-33
-
-
Lee, H.P.1
Jun, Y.C.2
Choi, J.K.3
Kim, J.I.4
Carp, R.I.5
Kim, Y.S.6
-
43
-
-
0042866044
-
Microglia density decreases with age in a mouse model of Huntington's disease
-
Ma L, Morton AJ, Nicholson LFB (2003) Microglia density decreases with age in a mouse model of Huntington's disease. Glia 43:274-280.
-
(2003)
Glia
, vol.43
, pp. 274-280
-
-
Ma, L.1
Morton, A.J.2
Nicholson, L.F.B.3
-
44
-
-
0033930508
-
Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie
-
Mabbott NA, Mackay F, Minns F, Bruce ME (2000) Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie. Nat Med 6:719-720.
-
(2000)
Nat Med
, vol.6
, pp. 719-720
-
-
Mabbott, N.A.1
Mackay, F.2
Minns, F.3
Bruce, M.E.4
-
45
-
-
0242363656
-
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
-
Mallucci G, Dickinson A, Linehan J, Klohn PC, Brandner S, Collinge J (2003) Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302:871-874.
-
(2003)
Science
, vol.302
, pp. 871-874
-
-
Mallucci, G.1
Dickinson, A.2
Linehan, J.3
Klohn, P.C.4
Brandner, S.5
Collinge, J.6
-
46
-
-
11844255779
-
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
-
Malm TM, Koistinaho M, Parepalo M, Vatanen T, Ooka A, Karlsson S, Koistinaho J (2005) Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice. Neurobiol Dis 18:134-142.
-
(2005)
Neurobiol Dis
, vol.18
, pp. 134-142
-
-
Malm, T.M.1
Koistinaho, M.2
Parepalo, M.3
Vatanen, T.4
Ooka, A.5
Karlsson, S.6
Koistinaho, J.7
-
47
-
-
0030758270
-
Evolution of a strain of CJD that induces BSE-like plaques
-
Manuelidis L, Fritch W, Xi YG (1997) Evolution of a strain of CJD that induces BSE-like plaques. Science 277:94-98.
-
(1997)
Science
, vol.277
, pp. 94-98
-
-
Manuelidis, L.1
Fritch, W.2
Xi, Y.G.3
-
48
-
-
0842284040
-
Neurons and astrocytes respond to prion infection by inducing microglia recruitment
-
Marella M, Chabry J (2004) Neurons and astrocytes respond to prion infection by inducing microglia recruitment. J Neurosci 24:620-627.
-
(2004)
J Neurosci
, vol.24
, pp. 620-627
-
-
Marella, M.1
Chabry, J.2
-
49
-
-
12544257289
-
Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment
-
Marella M, Gaggioli C, Batoz M, Deckert M, Tartare-Deckert S, Chabry J (2005) Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment. J Biol Chem 280:1529-1534.
-
(2005)
J Biol Chem
, vol.280
, pp. 1529-1534
-
-
Marella, M.1
Gaggioli, C.2
Batoz, M.3
Deckert, M.4
Tartare-Deckert, S.5
Chabry, J.6
-
50
-
-
19344364684
-
Hematopoietic cells maintain hematopoietic fates upon entering the brain
-
Massengale M, Wagers AJ, Vogel H, Weissman IL (2005) Hematopoietic cells maintain hematopoietic fates upon entering the brain. J Exp Med 201:1579-1589.
-
(2005)
J Exp Med
, vol.201
, pp. 1579-1589
-
-
Massengale, M.1
Wagers, A.J.2
Vogel, H.3
Weissman, I.L.4
-
51
-
-
0017871609
-
Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease). the nature and progression of spongiform change
-
Masters CL, Richardson Jr EP (1978) Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease). The nature and progression of spongiform change. Brain 101:333-344.
-
(1978)
Brain
, vol.101
, pp. 333-344
-
-
Masters, C.L.1
Richardson Jr., E.P.2
-
52
-
-
0027228057
-
Factors affecting retroviral vector function and structural integrity
-
McLachlin JR, Mittereder N, Dauche MB, Kadan M, Eglitis MA (1993) Factors affecting retroviral vector function and structural integrity. Virology 195:1-5.
-
(1993)
Virology
, vol.195
, pp. 1-5
-
-
McLachlin, J.R.1
Mittereder, N.2
Dauche, M.B.3
Kadan, M.4
Eglitis, M.A.5
-
53
-
-
0037418828
-
Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease
-
Meier P, Genoud N, Prinz M, Maissen M, Rulicke T, Zurbriggen A, Raeber AJ, Aguzzi A (2003) Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease. Cell 113:49-60.
-
(2003)
Cell
, vol.113
, pp. 49-60
-
-
Meier, P.1
Genoud, N.2
Prinz, M.3
Maissen, M.4
Rulicke, T.5
Zurbriggen, A.6
Raeber, A.J.7
Aguzzi, A.8
-
54
-
-
0023076202
-
Role of phagocytes in experimental scrapie in hamsters
-
(Paris)
-
Michel B, Tamalet J, Bongrand P, Gambarelli D, Gastaut JL (1987) Role of phagocytes in experimental scrapie in hamsters. Rev Neurol (Paris) 143:526-531.
-
(1987)
Rev Neurol
, vol.143
, pp. 526-531
-
-
Michel, B.1
Tamalet, J.2
Bongrand, P.3
Gambarelli, D.4
Gastaut, J.L.5
-
55
-
-
0025789126
-
A comparative immunohistochemical study of Kuru and senile plaques with a special reference to glial reactions at various stages of amyloid plaque formation
-
Miyazono M, Iwaki T, Kitamoto T, Kaneko Y, Doh-ura K, Tateishi J (1991) A comparative immunohistochemical study of Kuru and senile plaques with a special reference to glial reactions at various stages of amyloid plaque formation. Am J Pathol 139:589-598.
-
(1991)
Am J Pathol
, vol.139
, pp. 589-598
-
-
Miyazono, M.1
Iwaki, T.2
Kitamoto, T.3
Kaneko, Y.4
Doh-ura, K.5
Tateishi, J.6
-
56
-
-
0034686002
-
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
-
Montrasio F, Frigg R, Glatzel M, Klein MA, Mackay F, Aguzzi A, Weissmann C (2000) Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science 288:1257-1259.
-
(2000)
Science
, vol.288
, pp. 1257-1259
-
-
Montrasio, F.1
Frigg, R.2
Glatzel, M.3
Klein, M.A.4
Mackay, F.5
Aguzzi, A.6
Weissmann, C.7
-
57
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn A, Kirchhoff F, Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308:1314-1318.
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
58
-
-
0342592138
-
Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton
-
Nolte C, Moller T, Walter T, Kettenmann H (1996) Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton. Neuroscience 73:1091-1107.
-
(1996)
Neuroscience
, vol.73
, pp. 1091-1107
-
-
Nolte, C.1
Moller, T.2
Walter, T.3
Kettenmann, H.4
-
59
-
-
0036230174
-
Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: Evidence against dendritic cell involvement in neuroinvasion
-
Oldstone MB, Race R, Thomas D, Lewicki H, Homann D, Smelt S, Holz A, Koni P, Lo D, Chesebro B, Flavell R (2002) Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion. J Virol 76:4357-4363.
-
(2002)
J Virol
, vol.76
, pp. 4357-4363
-
-
Oldstone, M.B.1
Race, R.2
Thomas, D.3
Lewicki, H.4
Homann, D.5
Smelt, S.6
Holz, A.7
Koni, P.8
Lo, D.9
Chesebro, B.10
Flavell, R.11
-
60
-
-
0030921664
-
Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo
-
Persons DA, Allay JA, Allay ER, Smeyne RJ, Ashmun RA, Sorrentino BP, Nienhuis AW (1997) Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. Blood 90:1777-1786.
-
(1997)
Blood
, vol.90
, pp. 1777-1786
-
-
Persons, D.A.1
Allay, J.A.2
Allay, E.R.3
Smeyne, R.J.4
Ashmun, R.A.5
Sorrentino, B.P.6
Nienhuis, A.W.7
-
61
-
-
27744459883
-
Coexistence of multiple PrPSc types in invividuals with Creutzfeld-Jakob disease
-
Polymenidou M, Stoeck K, Glatzel M, Vey M, Bellon A, Aguzzi A (2005) Coexistence of multiple PrPSc types in invividuals with Creutzfeld-Jakob disease. Lancet Neurol 4:805-814.
-
(2005)
Lancet Neurol
, vol.4
, pp. 805-814
-
-
Polymenidou, M.1
Stoeck, K.2
Glatzel, M.3
Vey, M.4
Bellon, A.5
Aguzzi, A.6
-
62
-
-
0035956418
-
Neogenesis of cerebellar Purkinje neurons from gene-marked bone marrow cells in vivo
-
Priller J, Persons DA, Klett FF, Kempermann G, Kreutzberg GW, Dirnagl U (2001a) Neogenesis of cerebellar Purkinje neurons from gene-marked bone marrow cells in vivo. J Cell Biol 155:733-738.
-
(2001)
J Cell Biol
, vol.155
, pp. 733-738
-
-
Priller, J.1
Persons, D.A.2
Klett, F.F.3
Kempermann, G.4
Kreutzberg, G.W.5
Dirnagl, U.6
-
63
-
-
0035658031
-
Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment
-
Priller J, Flügel A, Wehner T, Boentert M, Haas CA, Prinz M, Fernandez-Klett F, Prass K, Bechmann I, de Boer BA, Frotscher M, Kreutzberg GW, Persons DA, Dirnagl U (2001b) Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment. Nat Med 7:1356-1361.
-
(2001)
Nat Med
, vol.7
, pp. 1356-1361
-
-
Priller, J.1
Flügel, A.2
Wehner, T.3
Boentert, M.4
Haas, C.A.5
Prinz, M.6
Fernandez-Klett, F.7
Prass, K.8
Bechmann, I.9
De Boer, B.A.10
Frotscher, M.11
Kreutzberg, G.W.12
Persons, D.A.13
Dirnagl, U.14
-
64
-
-
0032970384
-
Murine microglial cells produce and respond to interleukin-18
-
Prinz M, Hanisch UK (1999) Murine microglial cells produce and respond to interleukin-18. J Neurochem 72:2215-2218.
-
(1999)
J Neurochem
, vol.72
, pp. 2215-2218
-
-
Prinz, M.1
Hanisch, U.K.2
-
65
-
-
0037154263
-
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells
-
Prinz M, Montrasio F, Klein MA, Schwarz P, Priller J, Odermatt B, Pfeffer K, Aguzzi A (2002) Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc Natl Acad Sci USA 99:919-924.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 919-924
-
-
Prinz, M.1
Montrasio, F.2
Klein, M.A.3
Schwarz, P.4
Priller, J.5
Odermatt, B.6
Pfeffer, K.7
Aguzzi, A.8
-
66
-
-
0242499506
-
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
-
Prinz M, Heikenwalder M, Junt T, Schwarz P, Glatzel M, Heppner FL, Fu YX, Lipp M, Aguzzi A (2003) Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature 425:957-962.
-
(2003)
Nature
, vol.425
, pp. 957-962
-
-
Prinz, M.1
Heikenwalder, M.2
Junt, T.3
Schwarz, P.4
Glatzel, M.5
Heppner, F.L.6
Fu, Y.X.7
Lipp, M.8
Aguzzi, A.9
-
67
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner SB (1982) Novel proteinaceous infectious particles cause scrapie. Science 216:136-144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
68
-
-
0020080097
-
Measurement of the scrapie agent using an incubation time interval assay
-
Prusiner SB, Cochran SP, Groth DF, Downey DE, Bowman KA, Martinez HM (1982) Measurement of the scrapie agent using an incubation time interval assay. Ann Neurol 11:353-358.
-
(1982)
Ann Neurol
, vol.11
, pp. 353-358
-
-
Prusiner, S.B.1
Cochran, S.P.2
Groth, D.F.3
Downey, D.E.4
Bowman, K.A.5
Martinez, H.M.6
-
69
-
-
33748988258
-
Aβ 42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
-
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, Calhoun ME, Jäggi F, Wolburg H, Gengler S, Haass C, Ghetti B, Czech C, Hölscher C, Mathews PM, Jucker M (2006) Aβ 42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep 7:940-946.
-
(2006)
EMBO Rep
, vol.7
, pp. 940-946
-
-
Radde, R.1
Bolmont, T.2
Kaeser, S.A.3
Coomaraswamy, J.4
Lindau, D.5
Stoltze, L.6
Calhoun, M.E.7
Jäggi, F.8
Wolburg, H.9
Gengler, S.10
Haass, C.11
Ghetti, B.12
Czech, C.13
Hölscher, C.14
Mathews, P.M.15
Jucker, M.16
-
70
-
-
32344440522
-
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
-
Simard AR, Soulet D, Gowing G, Julien J-P, Rivest S (2006) Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 49:489-502.
-
(2006)
Neuron
, vol.49
, pp. 489-502
-
-
Simard, A.R.1
Soulet, D.2
Gowing, G.3
Julien, J.-P.4
Rivest, S.5
-
71
-
-
30644479563
-
Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice
-
Stalder AK, Ermini F, Bondolfi L, Krenger W, Burbach GJ, Deller T, Coomaraswamy J, Staufenbiel M, Landmann R, Jucker M (2005) Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice. J Neurosci 25:11125-11132.
-
(2005)
J Neurosci
, vol.25
, pp. 11125-11132
-
-
Stalder, A.K.1
Ermini, F.2
Bondolfi, L.3
Krenger, W.4
Burbach, G.J.5
Deller, T.6
Coomaraswamy, J.7
Staufenbiel, M.8
Landmann, R.9
Jucker, M.10
-
72
-
-
0031942743
-
Microglia and the development of spongiform change in Creutzfeldt-Jakob disease
-
von Eitzen U, Egensperger R, Kösel S, Grasbon-Frodl EM, Imai Y, Bise K, Kohsaka S, Mehraein P, Graeber MB (1998) Microglia and the development of spongiform change in Creutzfeldt-Jakob disease. J Neuropathol Exp Neurol 57:246-256.
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 246-256
-
-
Von Eitzen, U.1
Egensperger, R.2
Kösel, S.3
Grasbon-Frodl, E.M.4
Imai, Y.5
Bise, K.6
Kohsaka, S.7
Mehraein, P.8
Graeber, M.B.9
-
73
-
-
0030958078
-
Immunocytochemical evaluation of blood-brain barrier to endogenous albumin in scrapie-infected mice
-
(Berl)
-
Vorbrodt AW, Dobrogowska DH, Tarnawski M, Meeker HC, Carp RI (1997) Immunocytochemical evaluation of blood-brain barrier to endogenous albumin in scrapie-infected mice. Acta Neuropathol (Berl) 93:341-348.
-
(1997)
Acta Neuropathol
, vol.93
, pp. 341-348
-
-
Vorbrodt, A.W.1
Dobrogowska, D.H.2
Tarnawski, M.3
Meeker, H.C.4
Carp, R.I.5
-
74
-
-
0031127379
-
PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie
-
Williams A, Lucassen PJ, Ritchie D, Bruce M (1997) PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie. Exp Neurol 144:433-438.
-
(1997)
Exp Neurol
, vol.144
, pp. 433-438
-
-
Williams, A.1
Lucassen, P.J.2
Ritchie, D.3
Bruce, M.4
-
76
-
-
0029091646
-
Monocyte recruitment into the scrapie-affected brain
-
(Berl)
-
Williams AE, Ryder S, Blakemore WF (1995) Monocyte recruitment into the scrapie-affected brain. Acta Neuropathol (Berl) 90:164-169.
-
(1995)
Acta Neuropathol
, vol.90
, pp. 164-169
-
-
Williams, A.E.1
Ryder, S.2
Blakemore, W.F.3
-
77
-
-
0021088043
-
Increased blood-brain barrier permeability in scrapieinfected mice
-
Wisniewski HM, Lossinsky AS, Moretz RC, Vorbrodt AW, Lassmann H, Carp RI (1983) Increased blood-brain barrier permeability in scrapieinfected mice. J Neuropathol Exp Neurol 42:615-626.
-
(1983)
J Neuropathol Exp Neurol
, vol.42
, pp. 615-626
-
-
Wisniewski, H.M.1
Lossinsky, A.S.2
Moretz, R.C.3
Vorbrodt, A.W.4
Lassmann, H.5
Carp, R.I.6
-
78
-
-
0029431597
-
MRI of Creutzfeldt-Jakob disease: Asymmetric high signal intensity of the basal ganglia
-
Yoon SS, Chan S, Chin S, Lee K, Goodman RR (1995) MRI of Creutzfeldt-Jakob disease: asymmetric high signal intensity of the basal ganglia. Neurology 45:1932-1933.
-
(1995)
Neurology
, vol.45
, pp. 1932-1933
-
-
Yoon, S.S.1
Chan, S.2
Chin, S.3
Lee, K.4
Goodman, R.R.5
|