Immunocytochemical evaluation of blood-brain barrier to endogenous albumin in scrapie-infected mice

Acta Neuropathologica

Volumn 93, Issue 4, 1997, Pages 341-348

  Vorbrodt, A W ^a   Dobrogowska, D H ^a   Tarnawski, M ^a   Meeker, H C ^a   Carp, R I ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Albumin immunocytochemistry; Amyloid angiopathy; Amyloid plaques; Blood brain barrier; Scrapie infection

Indexed keywords

ALBUMIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; CEREBELLUM; FEMALE; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; MALE; MOUSE; NEUROPATHOLOGY; NEUROPIL; NONHUMAN; PRIORITY JOURNAL; SCRAPIE; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN CHEMISTRY; CEREBELLUM; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL CORTEX; FEMALE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED STRAINS; SCRAPIE; SERUM ALBUMIN;

EID: 0030958078     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050625     Document Type: Article

References (23)

1. Bruce ME, Dickinson AG, Fraser H (1976) Cerebral amyloidosis in scrapie in the mouse: effect of agent strain and mouse genotype. Neuropathol Appl Neurobiol 2:471-478
2. Ghitescu L, Bendayan M (1992) Transendothelial transport of serum albumin: a quantitative immunocytochemical study. J Cell Biol 117:745-755
3. Gilmour JS, Bruce ME, Mackellar A (1985) Cerebrovascular amyloidosis in scrapie-affected sheep. Neuropathol Appl Neurobiol 11:173-183
4. Ishii T, Haga S (1976) Immuno-electron microscopic localization of immunoglobulins in amyloid fibrils of senile plaques. Acta Neuropathol (Berl) 36:243-249
5. Ishii T, Haga S, Shimizu F (1975) Identification of components of immunoglobulins in senile plaques by means of fluorescent antibody technique. Acta Neuropathol (Berl) 32:157-162
6. Kalaria RN (1992) The blood-brain barrier and cerebral microcirculation in Alzheimer disease. Cerebrovasc Brain Metab Rev 4:226-260
7. Kalaria RN, Kroon SN, Perry G (1992) Serum proteins and the blood-brain barrier in the pathogenesis of Alzheimer's disease (abstract). Neurobiol Aging 13 [Suppl 1]:S86
8. Kurbel S, Kurbel B (1995) Mechanisms of prion diseases described as long-lasting disorders of the blood-brain barrier system. Med Hypotheses 5:543-544
9. Mann DMA, Davies JS, Hawkes J, Yates PO (1982) Immunohistochemical staining of senile plaques. Neuropathol Appl Neurobiol 8:55-61
10. Shirahama T, Skinner M, Westermark P, Rubino A, Cohen AS, Brun A, Kemper TL (1982) Prealbumin as a common constituent in the neuritic plaque, in the neurofibrillary tangle and in the microangiopathic lesion. Am J Pathol 107:41-50
11. Slemmon JR, Hughes CM, Campbell GA, Flood DG (1994) Increased levels of hemoglobin-derived and other peptides in Alzheimer's disease cerebellum. J Neurosci 14:2225-2235
12. Snow AD, Kisilevsky R, Willmer J, Prusiner SB, DeArmond SJ (1989) Sulfated glycosaminoglycans in amyloid plaques of prion diseases. Acta Neuropathol 77:337-342
13. Torack RM, Lynch RG (1981) Cytochemistry of brain amyloid in adult dementia. Acta Neuropathol (Berl) 53:189-196
14. Vorbrodt AW, Dobrogowska DH (1994) Immunocytochemical evaluation of blood-brain barrier to endogenous albumin in adult, newborn and aged mice. Folia Histochem Cytobiol 32:63-70
15. Vorbrodt AW, Lossinsky AS, Wisniewski HM; Moretz RC, Iwanowski L (1981) Ultrastructural cytochemical studies of cerebral microvasculature in scrapie infected mice. Acta. Neuropathol (Berl) 53:203-211
16. Vorbrodt AW, Dobrogowska DH, Kim YS, Lossinsky AS, Wisniewski HM (1988) Ultrastructural studies of glycoconjugates in brain micro-blood vessels and amyloid plaques of scrapie-infected mice. Acta Neuropathol (Berl) 75:277-287
17. Vorbrodt AW, Dobrogowska DH, Lossinsky AS, Wisniewski HM (1990) Changes in the distribution of anionic sites in brain micro-blood vessels with and without amyloid deposits in scrapie-infected mice. Acta Neuropathol 79:355-363
18. Vorbrodt AW, Dobrogowska DH, Ueno M, Lossinsky AS (1995) Immunocytochemical studies of protamine-induced blood-brain barrier opening to endogenous albumin. Acta Neuropathol 89:491-499
19. Wisniewski HM, Kozlowski PB (1982) Evidence for blood-brain barrier changes in senile dementia of the Alzheimer type (SDAT). Ann NY Acad Sci 396:119-129
20. Wisniewski HM, Lossinsky AS, Moretz RC, Vorbrodt AW (1981) Neuritic plaque formation and blood-brain barrier (BBB) changes in scrapie (abstract). J Neurpathol Exp Neurol 40:342
21. Wisniewski HM, Moretz RC, Lossinsky AS (1981) Evidence for induction of localized amyloid deposits and neuritic plaques by an infectious agent. Ann Neurol 10:517-522
22. Wisniewski HM, Lossinsky AS, Moretz RC, Vorbrodt AW, Lassmann H, Carp RI (1983) Increased blood-brain barrier permeability in scrapie-infected mice. J Neuropathol Exp Neurol 42:615-626
23. Wisniewski HM, Currie JR, Brown HR, Barcikowska M, Wegiel J, Vorbrodt AW (1989) Amyloidogenesis in Alzheimer disease and scrapie. In: Iqbal K, Wisniewski HM, Winblad B (eds) Alzheimer's disease and related disorders (Progress in clinical and biological research, vol 317). Alan R. Liss, New York, pp 869-876