Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment

Journal of Biological Chemistry

Volumn 280, Issue 2, 2005, Pages 1529-1534

  Marella, Mathieu ^a   Gaggioli, Cédric ^b   Batoz, Michèle ^c   Deckert, Marcel ^c   Tartare Deckert, Sophie ^b   Chabry, Joëlle ^a  

^a CNRS   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; CELLS; ENZYMES; NEUROLOGY; PATHOLOGY; RNA;

CHEMOKINES; CHEMOTTRACTION; MICROGLIA TREATMENT; PATHOLOGICAL PRION PROTEIN (PRPRES);

PROTEINS;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CHEMOATTRACTANT; EARLY GROWTH RESPONSE FACTOR 1; LAMININ RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PRION PROTEIN; RANTES;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; MICROGLIA; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; UPREGULATION;

ANIMALS; CELL LINE; CELL MOVEMENT; CELLS, CULTURED; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; ETS-DOMAIN PROTEIN ELK-1; FLAVONOIDS; GENE EXPRESSION REGULATION; IMMEDIATE-EARLY PROTEINS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NEURONS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PRPC PROTEINS; PRPSC PROTEINS; RANTES; REPRESSOR PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 12544257289     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410966200     Document Type: Article

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