-
1
-
-
19444376971
-
Drug metabolism and variability among patients in drug response
-
Wilkinson G.R. Drug metabolism and variability among patients in drug response. N Engl J Med 352 (2005) 2211-2221
-
(2005)
N Engl J Med
, vol.352
, pp. 2211-2221
-
-
Wilkinson, G.R.1
-
2
-
-
0346728729
-
The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability
-
Chan L.M., Lowes S., and Hirst B.H. The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability. Eur J Pharm Sci 21 (2004) 25-51
-
(2004)
Eur J Pharm Sci
, vol.21
, pp. 25-51
-
-
Chan, L.M.1
Lowes, S.2
Hirst, B.H.3
-
4
-
-
0346100571
-
Enterohepatic bile salt transporters in normal physiology and liver disease
-
Kullak-Ublick G.A., Stieger B., and Meier P.J. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology 126 (2004) 322-342
-
(2004)
Gastroenterology
, vol.126
, pp. 322-342
-
-
Kullak-Ublick, G.A.1
Stieger, B.2
Meier, P.J.3
-
5
-
-
0022537845
-
Clinical pharmacokinetics and pharmacological effects of carbamazepine and carbamazepine-10,11-epoxide. An update
-
Bertilsson L., and Tomson T. Clinical pharmacokinetics and pharmacological effects of carbamazepine and carbamazepine-10,11-epoxide. An update. Clin Pharmacokinet 11 (1986) 177-198
-
(1986)
Clin Pharmacokinet
, vol.11
, pp. 177-198
-
-
Bertilsson, L.1
Tomson, T.2
-
6
-
-
0028300816
-
Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation
-
Kerr B.M., Thummel K.E., Wurden C.J., Klein S.M., Kroetz D.L., Gonzalez F.J., et al. Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation. Biochem Pharmacol 47 (1994) 1969-1979
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 1969-1979
-
-
Kerr, B.M.1
Thummel, K.E.2
Wurden, C.J.3
Klein, S.M.4
Kroetz, D.L.5
Gonzalez, F.J.6
-
7
-
-
0030438701
-
Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene
-
Kitteringham N.R., Davis C., Howard N., Pirmohamed M., and Park B.K. Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene. J Pharmacol Exp Ther 278 (1996) 1018-1027
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 1018-1027
-
-
Kitteringham, N.R.1
Davis, C.2
Howard, N.3
Pirmohamed, M.4
Park, B.K.5
-
8
-
-
0029815563
-
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update
-
Spina E., Pisani F., and Perucca E. Clinically significant pharmacokinetic drug interactions with carbamazepine. An update. Clin Pharmacokinet 31 (1996) 198-214
-
(1996)
Clin Pharmacokinet
, vol.31
, pp. 198-214
-
-
Spina, E.1
Pisani, F.2
Perucca, E.3
-
9
-
-
0014292570
-
Osteopathies in antiepileptic long-term therapy (preliminary report) [in German]
-
Kruse R. Osteopathies in antiepileptic long-term therapy (preliminary report) [in German]. Monatsschr Kinderheilkd 116 (1968) 378-381
-
(1968)
Monatsschr Kinderheilkd
, vol.116
, pp. 378-381
-
-
Kruse, R.1
-
10
-
-
17444428105
-
Carbamazepine induced osteomalacia: letter to the editor
-
Tunca A., Sayli U., Atalar H., and Dogruel H. Carbamazepine induced osteomalacia: letter to the editor. Acta Neurol Belg 105 (2005) 46-47
-
(2005)
Acta Neurol Belg
, vol.105
, pp. 46-47
-
-
Tunca, A.1
Sayli, U.2
Atalar, H.3
Dogruel, H.4
-
11
-
-
0002844952
-
Subnormal serum folate and macrocytosis associated with anticonvulsant drug therapy
-
Klipstein F.A. Subnormal serum folate and macrocytosis associated with anticonvulsant drug therapy. Blood 23 (1964) 68-86
-
(1964)
Blood
, vol.23
, pp. 68-86
-
-
Klipstein, F.A.1
-
12
-
-
0035064742
-
Folate, homocysteine and methionine loading in patients on carbamazepine
-
Apeland T., Mansoor M.A., Strandjord R.E., Vefring H., and Kristensen O. Folate, homocysteine and methionine loading in patients on carbamazepine. Acta Neurol Scand 103 (2001) 294-299
-
(2001)
Acta Neurol Scand
, vol.103
, pp. 294-299
-
-
Apeland, T.1
Mansoor, M.A.2
Strandjord, R.E.3
Vefring, H.4
Kristensen, O.5
-
13
-
-
0035859848
-
Early hormonal changes during valproate or carbamazepine treatment: a 3-month study
-
Rättyä J., Pakarinen A.J., Knip M., Repo-Outakoski M., Myllyla V.V., and Isojarvi J.I. Early hormonal changes during valproate or carbamazepine treatment: a 3-month study. Neurology 57 (2001) 440-444
-
(2001)
Neurology
, vol.57
, pp. 440-444
-
-
Rättyä, J.1
Pakarinen, A.J.2
Knip, M.3
Repo-Outakoski, M.4
Myllyla, V.V.5
Isojarvi, J.I.6
-
14
-
-
0034964158
-
Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation
-
LeCluyse E.L. Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation. Eur J Pharm Sci 13 (2001) 343-368
-
(2001)
Eur J Pharm Sci
, vol.13
, pp. 343-368
-
-
LeCluyse, E.L.1
-
15
-
-
0141532282
-
Sex is a major determinant of CYP3A4 expression in human liver
-
Wolbold R., Klein K., Burk O., Nussler A.K., Neuhaus P., Eichelbaum M., et al. Sex is a major determinant of CYP3A4 expression in human liver. Hepatology 38 (2003) 978-988
-
(2003)
Hepatology
, vol.38
, pp. 978-988
-
-
Wolbold, R.1
Klein, K.2
Burk, O.3
Nussler, A.K.4
Neuhaus, P.5
Eichelbaum, M.6
-
16
-
-
12344280017
-
Summaries of Affymetrix GeneChip probe level data
-
Irizarry R.A., Bolstad B.M., Collin F., Cope L.M., Hobbs B., and Speed T.P. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 31 (2003) e15
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Irizarry, R.A.1
Bolstad, B.M.2
Collin, F.3
Cope, L.M.4
Hobbs, B.5
Speed, T.P.6
-
17
-
-
33751114594
-
-
Available from: URL:www.affymetrix.com. Accessed Oct 25, 2005.
-
-
-
-
18
-
-
12244313858
-
Analysis of high density expression microarrays with signed-rank call algorithms
-
Liu W.M., Mei R., Di X., Ryder T.B., Hubbell E., Dee S., et al. Analysis of high density expression microarrays with signed-rank call algorithms. Bioinformatics 18 (2002) 1593-1599
-
(2002)
Bioinformatics
, vol.18
, pp. 1593-1599
-
-
Liu, W.M.1
Mei, R.2
Di, X.3
Ryder, T.B.4
Hubbell, E.5
Dee, S.6
-
19
-
-
0034718544
-
CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)
-
Handschin C., Podvinec M., and Meyer U.A. CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR). Proc Natl Acad Sci U S A 97 (2000) 10769-10774
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10769-10774
-
-
Handschin, C.1
Podvinec, M.2
Meyer, U.A.3
-
20
-
-
0032702726
-
The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
-
Goodwin B., Hodgson E., and Liddle C. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Mol Pharmacol 56 (1999) 1329-1339
-
(1999)
Mol Pharmacol
, vol.56
, pp. 1329-1339
-
-
Goodwin, B.1
Hodgson, E.2
Liddle, C.3
-
21
-
-
0344740559
-
Induction of drug metabolism: the role of nuclear receptors
-
Handschin C., and Meyer U.A. Induction of drug metabolism: the role of nuclear receptors. Pharmacol Rev 55 (2003) 649-673
-
(2003)
Pharmacol Rev
, vol.55
, pp. 649-673
-
-
Handschin, C.1
Meyer, U.A.2
-
22
-
-
0030792284
-
Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19
-
Bertilsson L., Tybring G., Widen J., Chang M., and Tomson T. Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19. Br J Clin Pharmacol 44 (1997) 186-189
-
(1997)
Br J Clin Pharmacol
, vol.44
, pp. 186-189
-
-
Bertilsson, L.1
Tybring, G.2
Widen, J.3
Chang, M.4
Tomson, T.5
-
23
-
-
0035118826
-
Induction of CYP2C genes in human hepatocytes in primary culture
-
Gerbal-Chaloin S., Pascussi J.M., Pichard-Garcia L., Daujat M., Waechter F., Fabre J.M., et al. Induction of CYP2C genes in human hepatocytes in primary culture. Drug Metab Dispos 29 (2001) 242-251
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 242-251
-
-
Gerbal-Chaloin, S.1
Pascussi, J.M.2
Pichard-Garcia, L.3
Daujat, M.4
Waechter, F.5
Fabre, J.M.6
-
24
-
-
0037379409
-
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes
-
Madan A., Graham R.A., Carroll K.M., Mudra D.R., Burton L.A., Krueger L.A., et al. Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes. Drug Metab Dispos 31 (2003) 421-431
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 421-431
-
-
Madan, A.1
Graham, R.A.2
Carroll, K.M.3
Mudra, D.R.4
Burton, L.A.5
Krueger, L.A.6
-
25
-
-
0042844649
-
Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter
-
Chen Y., Ferguson S.S., Negishi M., and Goldstein J.A. Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter. Mol Pharmacol 64 (2003) 316-324
-
(2003)
Mol Pharmacol
, vol.64
, pp. 316-324
-
-
Chen, Y.1
Ferguson, S.S.2
Negishi, M.3
Goldstein, J.A.4
-
26
-
-
0036891068
-
Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19
-
Lakehal F., Wurden C.J., Kalhorn T.F., and Levy R.H. Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19. Epilepsy Res 52 (2002) 79-83
-
(2002)
Epilepsy Res
, vol.52
, pp. 79-83
-
-
Lakehal, F.1
Wurden, C.J.2
Kalhorn, T.F.3
Levy, R.H.4
-
27
-
-
0028900559
-
CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients
-
Sotaniemi E.A., Rautio A., Backstrom M., Arvela P., and Pelkonen O. CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients. Br J Clin Pharmacol 39 (1995) 71-76
-
(1995)
Br J Clin Pharmacol
, vol.39
, pp. 71-76
-
-
Sotaniemi, E.A.1
Rautio, A.2
Backstrom, M.3
Arvela, P.4
Pelkonen, O.5
-
28
-
-
0037931737
-
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
-
Maglich J.M., Parks D.J., Moore L.B., Collins J.L., Goodwin B., Billin A.N., et al. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. J Biol Chem 278 (2003) 17277-17283
-
(2003)
J Biol Chem
, vol.278
, pp. 17277-17283
-
-
Maglich, J.M.1
Parks, D.J.2
Moore, L.B.3
Collins, J.L.4
Goodwin, B.5
Billin, A.N.6
-
29
-
-
0037515661
-
A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression
-
Wang H., Faucette S., Sueyoshi T., Moore R., Ferguson S., Negishi M., et al. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression. J Biol Chem 278 (2003) 14146-14152
-
(2003)
J Biol Chem
, vol.278
, pp. 14146-14152
-
-
Wang, H.1
Faucette, S.2
Sueyoshi, T.3
Moore, R.4
Ferguson, S.5
Negishi, M.6
-
30
-
-
0038768712
-
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
-
Denison M.S., and Nagy S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 43 (2003) 309-334
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 309-334
-
-
Denison, M.S.1
Nagy, S.R.2
-
31
-
-
0036765785
-
Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
-
Maglich J.M., Stoltz C.M., Goodwin B., Hawkins-Brown D., Moore J.T., and Kliewer S.A. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol Pharmacol 62 (2002) 638-646
-
(2002)
Mol Pharmacol
, vol.62
, pp. 638-646
-
-
Maglich, J.M.1
Stoltz, C.M.2
Goodwin, B.3
Hawkins-Brown, D.4
Moore, J.T.5
Kliewer, S.A.6
-
32
-
-
0035201366
-
Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays
-
Rae J.M., Johnson M.D., Lippman M.E., and Flockhart D.A. Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. J Pharmacol Exp Ther 299 (2001) 849-857
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 849-857
-
-
Rae, J.M.1
Johnson, M.D.2
Lippman, M.E.3
Flockhart, D.A.4
-
34
-
-
0034595650
-
Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol
-
Li-Hawkins J., Lund E.G., Bronson A.D., and Russell D.W. Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol. J Biol Chem 275 (2000) 16543-16549
-
(2000)
J Biol Chem
, vol.275
, pp. 16543-16549
-
-
Li-Hawkins, J.1
Lund, E.G.2
Bronson, A.D.3
Russell, D.W.4
-
35
-
-
1642457373
-
CYP3A induction by liver X receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor
-
Shenoy S.D., Spencer T.A., Mercer-Haines N.A., Alipour M., Gargano M.D., Runge-Morris M., et al. CYP3A induction by liver X receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor. Drug Metab Dispos 32 (2004) 66-71
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 66-71
-
-
Shenoy, S.D.1
Spencer, T.A.2
Mercer-Haines, N.A.3
Alipour, M.4
Gargano, M.D.5
Runge-Morris, M.6
-
36
-
-
0037422578
-
Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor
-
Goodwin B., Gauthier K.C., Umetani M., Watson M.A., Lochansky M.I., Collins J.L., et al. Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor. Proc Natl Acad Sci U S A 100 (2003) 223-228
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 223-228
-
-
Goodwin, B.1
Gauthier, K.C.2
Umetani, M.3
Watson, M.A.4
Lochansky, M.I.5
Collins, J.L.6
-
37
-
-
0037417994
-
Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance
-
Dussault I., Yoo H.D., Lin M., Wang E., Fan M., Batta A.K., et al. Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance. Proc Natl Acad Sci U S A 100 (2003) 833-838
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 833-838
-
-
Dussault, I.1
Yoo, H.D.2
Lin, M.3
Wang, E.4
Fan, M.5
Batta, A.K.6
-
38
-
-
0037972688
-
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor
-
Rosenfeld J.M., Vargas Jr. R., Xie W., and Evans R.M. Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. Mol Endocrinol 17 (2003) 1268-1282
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1268-1282
-
-
Rosenfeld, J.M.1
Vargas Jr., R.2
Xie, W.3
Evans, R.M.4
-
39
-
-
0036142429
-
Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital
-
Ueda A., Hamadeh H.K., Webb H.K., Yamamoto Y., Sueyoshi T., Afshari C.A., et al. Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital. Mol Pharmacol 61 (2002) 1-6
-
(2002)
Mol Pharmacol
, vol.61
, pp. 1-6
-
-
Ueda, A.1
Hamadeh, H.K.2
Webb, H.K.3
Yamamoto, Y.4
Sueyoshi, T.5
Afshari, C.A.6
-
40
-
-
0035740329
-
Biotransformation of xenobiotics by amine oxidases
-
Benedetti M.S. Biotransformation of xenobiotics by amine oxidases. Fundam Clin Pharmacol 15 (2001) 75-84
-
(2001)
Fundam Clin Pharmacol
, vol.15
, pp. 75-84
-
-
Benedetti, M.S.1
-
41
-
-
0034128936
-
Human UDP-glucuronosyltransferases: metabolism, expression, and disease
-
Tukey R.H., and Strassburg C.P. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annu Rev Pharmacol Toxicol 40 (2000) 581-616
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
42
-
-
20444500240
-
Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers
-
Chung J.Y., Cho J.Y., Yu K.S., Kim J.R., Jung H.R., Lim K.S., et al. Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers. Clin Pharmacol Ther 77 (2005) 486-494
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 486-494
-
-
Chung, J.Y.1
Cho, J.Y.2
Yu, K.S.3
Kim, J.R.4
Jung, H.R.5
Lim, K.S.6
-
43
-
-
0035799361
-
Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase
-
Levesque E., Turgeon D., Carrier J.S., Montminy V., Beaulieu M., and Belanger A. Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase. Biochemistry 40 (2001) 3869-3881
-
(2001)
Biochemistry
, vol.40
, pp. 3869-3881
-
-
Levesque, E.1
Turgeon, D.2
Carrier, J.S.3
Montminy, V.4
Beaulieu, M.5
Belanger, A.6
-
44
-
-
0037108916
-
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR)
-
Sonoda J., Xie W., Rosenfeld J.M., Barwick J.L., Guzelian P.S., and Evans R.M. Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR). Proc Natl Acad Sci U S A 99 (2002) 13801-13806
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13801-13806
-
-
Sonoda, J.1
Xie, W.2
Rosenfeld, J.M.3
Barwick, J.L.4
Guzelian, P.S.5
Evans, R.M.6
-
45
-
-
0036707624
-
Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes
-
Duanmu Z., Locke D., Smigelski J., Wu W., Dahn M.S., Falany C.N., et al. Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes. Drug Metab Dispos 30 (2002) 997-1004
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 997-1004
-
-
Duanmu, Z.1
Locke, D.2
Smigelski, J.3
Wu, W.4
Dahn, M.S.5
Falany, C.N.6
-
46
-
-
0034534035
-
Epoxide hydrolases: biochemistry and molecular biology
-
Fretland A.J., and Omiecinski C.J. Epoxide hydrolases: biochemistry and molecular biology. Chem Biol Interact 129 (2000) 41-59
-
(2000)
Chem Biol Interact
, vol.129
, pp. 41-59
-
-
Fretland, A.J.1
Omiecinski, C.J.2
-
47
-
-
0027497708
-
Preferential increase of glutathione S-transferase class alpha transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones
-
Morel F., Fardel O., Meyer D.J., Langouet S., Gilmore K.S., Meunier B., et al. Preferential increase of glutathione S-transferase class alpha transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones. Cancer Res 53 (1993) 231-234
-
(1993)
Cancer Res
, vol.53
, pp. 231-234
-
-
Morel, F.1
Fardel, O.2
Meyer, D.J.3
Langouet, S.4
Gilmore, K.S.5
Meunier, B.6
-
48
-
-
0034866270
-
Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors
-
Falkner K.C., Pinaire J.A., Xiao G.H., Geoghegan T.E., and Prough R.A. Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors. Mol Pharmacol 60 (2001) 611-619
-
(2001)
Mol Pharmacol
, vol.60
, pp. 611-619
-
-
Falkner, K.C.1
Pinaire, J.A.2
Xiao, G.H.3
Geoghegan, T.E.4
Prough, R.A.5
-
49
-
-
0031741776
-
Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids
-
Tong Z., Board P.G., and Anders M.W. Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids. Chem Res Toxicol 11 (1998) 1332-1338
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 1332-1338
-
-
Tong, Z.1
Board, P.G.2
Anders, M.W.3
-
50
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
Greiner B., Eichelbaum M., Fritz P., Kreichgauer H.P., von Richter O., Zundler J., et al. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Invest 104 (1999) 147-153
-
(1999)
J Clin Invest
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
von Richter, O.5
Zundler, J.6
-
51
-
-
0142150021
-
Induction of ABCC3 (MRP3) by pregnane X receptor activators
-
Teng S., Jekerle V., and Piquette-Miller M. Induction of ABCC3 (MRP3) by pregnane X receptor activators. Drug Metab Dispos 31 (2003) 1296-1299
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1296-1299
-
-
Teng, S.1
Jekerle, V.2
Piquette-Miller, M.3
-
52
-
-
0037169551
-
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
-
Kast H.R., Goodwin B., Tarr P.T., Jones S.A., Anisfeld A.M., Stoltz C.M., et al. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. J Biol Chem 277 (2002) 2908-2915
-
(2002)
J Biol Chem
, vol.277
, pp. 2908-2915
-
-
Kast, H.R.1
Goodwin, B.2
Tarr, P.T.3
Jones, S.A.4
Anisfeld, A.M.5
Stoltz, C.M.6
-
53
-
-
0036021113
-
The drug efflux pump MRP2: regulation of expression in physiopathological situations and by endogenous and exogenous compounds
-
Payen L., Sparfel L., Courtois A., Vernhet L., Guillouzo A., and Fardel O. The drug efflux pump MRP2: regulation of expression in physiopathological situations and by endogenous and exogenous compounds. Cell Biol Toxicol 18 (2002) 221-233
-
(2002)
Cell Biol Toxicol
, vol.18
, pp. 221-233
-
-
Payen, L.1
Sparfel, L.2
Courtois, A.3
Vernhet, L.4
Guillouzo, A.5
Fardel, O.6
-
54
-
-
0033724658
-
The effect of rifampin treatment on intestinal expression of human MRP transporters
-
Fromm M.F., Kauffmann H.M., Fritz P., Burk O., Kroemer H.K., Warzok R.W., et al. The effect of rifampin treatment on intestinal expression of human MRP transporters. Am J Pathol 157 (2000) 1575-1580
-
(2000)
Am J Pathol
, vol.157
, pp. 1575-1580
-
-
Fromm, M.F.1
Kauffmann, H.M.2
Fritz, P.3
Burk, O.4
Kroemer, H.K.5
Warzok, R.W.6
-
55
-
-
0042354831
-
Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport
-
Chen Z.S., Robey R.W., Belinsky M.G., Shchaveleva I., Ren X.Q., Sugimoto Y., et al. Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport. Cancer Res 63 (2003) 4048-4054
-
(2003)
Cancer Res
, vol.63
, pp. 4048-4054
-
-
Chen, Z.S.1
Robey, R.W.2
Belinsky, M.G.3
Shchaveleva, I.4
Ren, X.Q.5
Sugimoto, Y.6
-
56
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
Suzuki M., Suzuki H., Sugimoto Y., and Sugiyama Y. ABCG2 transports sulfated conjugates of steroids and xenobiotics. J Biol Chem 278 (2003) 22644-22649
-
(2003)
J Biol Chem
, vol.278
, pp. 22644-22649
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
57
-
-
0034801632
-
ABCA6, a novel a subclass ABC transporter
-
Kaminski W.E., Wenzel J.J., Piehler A., Langmann T., and Schmitz G. ABCA6, a novel a subclass ABC transporter. Biochem Biophys Res Commun 285 (2001) 1295-1301
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 1295-1301
-
-
Kaminski, W.E.1
Wenzel, J.J.2
Piehler, A.3
Langmann, T.4
Schmitz, G.5
-
58
-
-
0037944100
-
Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase
-
Taketani S., Kakimoto K., Ueta H., Masaki R., and Furukawa T. Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase. Blood 101 (2003) 3274-3280
-
(2003)
Blood
, vol.101
, pp. 3274-3280
-
-
Taketani, S.1
Kakimoto, K.2
Ueta, H.3
Masaki, R.4
Furukawa, T.5
-
59
-
-
0141925798
-
Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene
-
Fraser D.J., Zumsteg A., and Meyer U.A. Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene. J Biol Chem 278 (2003) 39392-39401
-
(2003)
J Biol Chem
, vol.278
, pp. 39392-39401
-
-
Fraser, D.J.1
Zumsteg, A.2
Meyer, U.A.3
-
60
-
-
0034982907
-
Differential effects of microsomal enzyme-inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2
-
Rausch-Derra L.C., Hartley D.P., Meier P.J., and Klaassen C.D. Differential effects of microsomal enzyme-inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2. Hepatology 33 (2001) 1469-1478
-
(2001)
Hepatology
, vol.33
, pp. 1469-1478
-
-
Rausch-Derra, L.C.1
Hartley, D.P.2
Meier, P.J.3
Klaassen, C.D.4
-
62
-
-
0034695673
-
beta-Lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter
-
Ganapathy M.E., Huang W., Rajan D.P., Carter A.L., Sugawara M., Iseki K., et al. beta-Lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. J Biol Chem 275 (2000) 1699-1707
-
(2000)
J Biol Chem
, vol.275
, pp. 1699-1707
-
-
Ganapathy, M.E.1
Huang, W.2
Rajan, D.P.3
Carter, A.L.4
Sugawara, M.5
Iseki, K.6
-
63
-
-
33645310407
-
Uptake of cardiovascular drugs into the human heart: expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5)
-
Grube M., Meyer zu Schwabedissen H.E., Prager D., Haney J., Moritz K.U., Meissner K., et al. Uptake of cardiovascular drugs into the human heart: expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5). Circulation 113 (2006) 1114-1122
-
(2006)
Circulation
, vol.113
, pp. 1114-1122
-
-
Grube, M.1
Meyer zu Schwabedissen, H.E.2
Prager, D.3
Haney, J.4
Moritz, K.U.5
Meissner, K.6
-
64
-
-
0037450436
-
The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors
-
Pascussi J.M., Gerbal-Chaloin S., Drocourt L., Maurel P., and Vilarem M.J. The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors. Biochim Biophys Acta 1619 (2003) 243-253
-
(2003)
Biochim Biophys Acta
, vol.1619
, pp. 243-253
-
-
Pascussi, J.M.1
Gerbal-Chaloin, S.2
Drocourt, L.3
Maurel, P.4
Vilarem, M.J.5
-
65
-
-
0036030926
-
Use of in vitro pregnane X receptor assays to assess CYP3A4 induction potential of drug candidates
-
Jones S.A., Moore L.B., Wisely G.B., and Kliewer S.A. Use of in vitro pregnane X receptor assays to assess CYP3A4 induction potential of drug candidates. Methods Enzymol 357 (2002) 161-170
-
(2002)
Methods Enzymol
, vol.357
, pp. 161-170
-
-
Jones, S.A.1
Moore, L.B.2
Wisely, G.B.3
Kliewer, S.A.4
-
66
-
-
0033525886
-
The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene
-
Sueyoshi T., Kawamoto T., Zelko I., Honkakoski P., and Negishi M. The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. J Biol Chem 274 (1999) 6043-6046
-
(1999)
J Biol Chem
, vol.274
, pp. 6043-6046
-
-
Sueyoshi, T.1
Kawamoto, T.2
Zelko, I.3
Honkakoski, P.4
Negishi, M.5
-
67
-
-
0035987895
-
CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes
-
Luo G., Cunningham M., Kim S., Burn T., Lin J., Sinz M., et al. CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes. Drug Metab Dispos 30 (2002) 795-804
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 795-804
-
-
Luo, G.1
Cunningham, M.2
Kim, S.3
Burn, T.4
Lin, J.5
Sinz, M.6
-
68
-
-
0142210233
-
Developmental expression of the major human hepatic CYP3A enzymes
-
Stevens J.C., Hines R.N., Gu C., Koukouritaki S.B., Manro J.R., Tandler P.J., et al. Developmental expression of the major human hepatic CYP3A enzymes. J Pharmacol Exp Ther 307 (2003) 573-582
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 573-582
-
-
Stevens, J.C.1
Hines, R.N.2
Gu, C.3
Koukouritaki, S.B.4
Manro, J.R.5
Tandler, P.J.6
-
69
-
-
0036236065
-
Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor
-
Ripp S.L., Fitzpatrick J.L., Peters J.M., and Prough R.A. Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor. Drug Metab Dispos 30 (2002) 570-575
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 570-575
-
-
Ripp, S.L.1
Fitzpatrick, J.L.2
Peters, J.M.3
Prough, R.A.4
-
70
-
-
0037132499
-
In vivo activation of the constitutive androstane receptor beta (CARbeta) by treatment with dehydroepiandrosterone (DHEA) or DHEA sulfate (DHEA-S)
-
Fujita A., Furutama D., Tanaka T., Sakai R., Koyama A., Hanafusa T., et al. In vivo activation of the constitutive androstane receptor beta (CARbeta) by treatment with dehydroepiandrosterone (DHEA) or DHEA sulfate (DHEA-S). FEBS Lett 532 (2002) 373-378
-
(2002)
FEBS Lett
, vol.532
, pp. 373-378
-
-
Fujita, A.1
Furutama, D.2
Tanaka, T.3
Sakai, R.4
Koyama, A.5
Hanafusa, T.6
-
71
-
-
0034721159
-
Humanized xenobiotic response in mice expressing nuclear receptor SXR
-
Xie W., Barwick J.L., Downes M., Blumberg B., Simon C.M., Nelson M.C., et al. Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature 406 (2000) 435-439
-
(2000)
Nature
, vol.406
, pp. 435-439
-
-
Xie, W.1
Barwick, J.L.2
Downes, M.3
Blumberg, B.4
Simon, C.M.5
Nelson, M.C.6
-
72
-
-
0035853165
-
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
-
Staudinger J.L., Goodwin B., Jones S.A., Hawkins-Brown D., MacKenzie K.I., LaTour A., et al. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci U S A 98 (2001) 3369-3374
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 3369-3374
-
-
Staudinger, J.L.1
Goodwin, B.2
Jones, S.A.3
Hawkins-Brown, D.4
MacKenzie, K.I.5
LaTour, A.6
-
73
-
-
0033060845
-
Carbamazepine induces multiple cytochrome P450 subfamilies in rats
-
Tateishi T., Asoh M., Nakura H., Watanabe M., Tanaka M., Kumai T., et al. Carbamazepine induces multiple cytochrome P450 subfamilies in rats. Chem Biol Interact 117 (1999) 257-268
-
(1999)
Chem Biol Interact
, vol.117
, pp. 257-268
-
-
Tateishi, T.1
Asoh, M.2
Nakura, H.3
Watanabe, M.4
Tanaka, M.5
Kumai, T.6
-
74
-
-
0029895113
-
Comparative effects of carbamazepine and carbamazepine-10,11-epoxide on hepatic cytochromes P450 in the rat
-
Panesar S.K., Bandiera S.M., and Abbott F.S. Comparative effects of carbamazepine and carbamazepine-10,11-epoxide on hepatic cytochromes P450 in the rat. Drug Metab Dispos 24 (1996) 619-627
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 619-627
-
-
Panesar, S.K.1
Bandiera, S.M.2
Abbott, F.S.3
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