Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes

Drug Metabolism and Disposition

Volumn 30, Issue 9, 2002, Pages 997-1004

  Duanmu, Zhengbo ^a   Locke, Deborah ^b   Smigelski, Jeffrey ^c   Wu, Wei ^d   Dahn, Michael S ^a   Falany, Charles N ^b   Kocarek, Thomas A ^c   Runge Morris, Melissa ^d  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

^d University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; ARYL SULFOTRANSFERASE; COLLAGENASE; DEXAMETHASONE; HYDROXYSTEROID SULFOTRANSFERASE; INSULIN; LIGAND; PREGNANE X RECEPTOR; RECOMBINANT HUMAN INSULIN; TRANSCRIPTION FACTOR; TRIAMCINOLONE ACETONIDE; ALCOHOL SULFOTRANSFERASE; GLUCOCORTICOID; SULFOTRANSFERASE; SULT1A1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME INDUCTION; ENZYME MECHANISM; ENZYME REGULATION; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE ISOLATION; HUMAN; HUMAN CELL; INSULIN METABOLISM; LIGAND BINDING; LIVER CELL CULTURE; LIVER PERFUSION; LIVER TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPORTER GENE; RNA ANALYSIS; SPECIES DIFFERENCE; STEROID THERAPY; SULT1A1 GENE; SULT2A1 GENE; TRANSCRIPTION REGULATION; BIOSYNTHESIS; CELL CULTURE; GENE EXPRESSION; GENETICS; LIVER CELL; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; CELLS, CULTURED; DEXAMETHASONE; GENE EXPRESSION; GLUCOCORTICOIDS, SYNTHETIC; HEPATOCYTES; HUMAN; MOLECULAR SEQUENCE DATA; SULFOTRANSFERASES; SUPPORT, U.S. GOV'T, P.H.S.; ARYLSULFOTRANSFERASE; GLUCOCORTICOIDS; HUMANS;

ANIMALIA;

EID: 0036707624     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.9.997     Document Type: Article

References (43)

1. Bile acid sulfotransferase 1 from rat liver sulfates bile acids and 3-hydroxy steroids: Purification. N-terminal amino acid sequence and kinetic properties
2. The senescence marker protein (SMP-2) of the rat liver: Purification, immunochemical characterization and age-dependent regulation
3. Immunological characterization of dehydroepiandrosterone sulfotransferase from human liver and adrenal
4. Cloning and expression of human liver dehydroepiandrosterone sulphotransferase
5. Transcriptional regulation of rat hepatic aryl sulfotransferase (SULT1A1) gene expression by glucocorticoids
6. Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning and characterization
7. Sulfation of minoxidil by human liver phenol sulfotransferase
8. Purification and characterization of human liver phenol-sulfating phenol sulfotransferase
9. Purification and characterization of human liver dehydroepiandrosterone sulphotransferase
10. Identification of a nuclear receptor that is activated by farnesol metabolites
11. Activation of benzylic alcohols to mutagens by rat and human sulfotransferases expression in Escherichia coll
12. Human jejunal estrogen sulfotransferase and dehydroepiandrosterone sulfotransferase: Immnunochemical characterization of individual variation
13. Enzymatic characterization and interspecies difference of phenol sulfotransferases, STIA forms
14. Sulfotransferases
15. Orphan nuclear receptors: Shifting endocrinology into reverse
16. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway
17. Interpreting cDNA sequences: Some insights from studies on translation
18. 14C]2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP)
19. Effects of pregnancy on the toxicity and metabolism of acetaminophen in mice
20. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
21. Ontogeny and hormonal basis of female-dominant rat hepatic sulfotransferases
22. Regulation of hepatic sulfotransferases by steroidal chemicals in rats
23. Identification of a nuclear receptor for bile acids
24. Human dehydroepiandrosterone sulfotransferase gene: Molecular cloning and structural characterization
25. Immunohistochemical localization of dehydroepiandrosterone sulfotransferase in human fetal tissues
26. Human liver steroid sulphotransferase sulphates bile acids
27. Phenol sulfotransferase pharmacogenetics in humans: Association of common SULT1A1 alleles with TS PST phenotype
28. Regulation of hepatic sulfotransferase gene expression by glucocorticoid hormones
29. Regulation of rat hepatic hydroxysteroid sulfotransferase (SULT2-40/41) gene expression by glucocorticoids: Evidence for a dual mechanism of transcriptional control
30. Characterization of bovine tracheobronchial phenol sulphotransferase cDNA and detection of mRNA regulation by cortisol
31. Induction of cytochrome P-450 by glucocorticoids in rat liver. II. Evidence that glucocorticoids regulate induction of cytochrome P450 by a nonclassical mechanism
32. Sulfation of α-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts
33. Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor
34. Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter
35. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
36. Use of human hepatocytes to study P450 gene induction
37. Expression and activity of dehydroepiandrosterone sulfotransferase in human gastric mucosa
38. Distinct regulation of two hydroxysteroid sulfotransferases, ST2A1 and ST2A2, by growth hormone: A unique type of growth hormone regulation in rats
39. Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα
40. The human nuclear xenobiotic receptor PXR: Structural determinants of directed promiscuity
41. Sequence analysis and expression of the cDNA for the phenol-sulfating form of human liver phenol sulfotransferase
42. Sex-dependent regulation by dexamethasone of murine hydroxysteroid sulfotransferase gene expression
43. Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein Ic gene promoter