Drug Transporters and Their Role in Tissue Distribution

Annual Reports in Medicinal Chemistry

Volumn 39, Issue , 2004, Pages 277-291

  Dantzig, Anne H ^a   Hillgren, Kathleen M ^a   de Alwis, Dinesh P ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748482627     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(04)39021-4     Document Type: Review

References (107)

1. Sadee W., Drubbisch V., and Amidon G.L. Pharm. Res 12 (1995) 1823
2. Sadee W., Graul R.C., and Lee A.Y. In: Amidon G., and Sadee W. (Eds). Classification of membrane transporters, in Membrane Transporters as Drug Targets (1999), Kluwer Academic/Plenum, New York 29
3. Dantzig A.H. Adv. Drug Del. Rev 23 (1997) 63
4. Rajan D.P., Kekuda R., Huang W., Devoe L.D., Leibach F.H., Prasad P.D., and Ganapathy V. Biochem. Biophys. Acta 1463 (2000) 6
5. Ganapathy V., Miyamoto Y., and Leibach F.H. Beitrage Zu Infusionstherapie und Klinische Ernahrung 17 (1987) 54
6. Dantzig A.H., Hoskins J., Tabas L.B., Bright S., Shepard R.L., Jenkins I.L., Duckworth D.C., Sportsman R., MacKensen D., Rosteck P.R., and Skatrud P.L. Science 264 (1994) 430
7. Landowski C., Sun D., Foster D., Menon S., Barnett J., Welage L., Ramachandran C., and Amidon G. J. Pharmacol. Exp. Ther 306 (2003) 778
8. http://www.gene.ucl.ac.uk/nomenclature/genefamily.shtml.
9. Kong W., Engel K., and Wang J. Curr. Drug Metab 5 (2004) 63
10. Huang M., Wang Y., Cogut S.B., Mitchell B.S., and Graves L.M. J. Pharmacol. Exp. Ther 304 (2003) 753
11. Mangravite L.M., Xiao G., and Giacomini K.M. Am. J. Physiol. Renal Physiol 284 (2003) F902
12. Uchino H., Kanai Y., Kim D.K., Wempe M.F., Chairoungdua A., Morimoto E., Anders M.W., and Endou H. Mol. Pharmacol 61 (2002) 729
13. Pinho M.J., Gomes P., Serrao M.P., Bonifacio M.J., and Soares-da-Silva P. Hypertension 42 (2003) 613
14. Brandsch M., Knutter I., and Leibach F.H. Eur. J. Pharm. Sci 21 (2004) 53
15. Zhu T., Chen X., Steel A., Hediger M., and Smith D. Pharm. Res 17 5 (2000) 526
16. Terada T., and Inui K. Curr. Drug Metab 5 (2004) 85
17. Daniel H., and Kottra G. Pflugers Archiv. Eur. J. Physiol 447 (2004) 610
18. Galic S., Schneider H.P., Broer A., Deitmer J.W., and Broer S. Biochem. J 376 (2003) 413
19. Li Y.H., Tanno M., Itoh T., and Yamada H. Intern. J. Pharm 191 (1999) 151
20. Daberkow R., White B., Cederberg R., Griffin J., and Zempleni J. J. Nutr 133 (2003) 2703
21. Menon R., and Barr W. Biopharm. Drug Dispos 23 (2002) 317
22. Lennernas H. Clin. Pharmacokinet 42 (2003) 1141
23. Iseki K., Sugawara M., Sato K., Naasani I., Hayakawa T., Kobayashi M., and Miyazaki K. J. Pharmacol. Exp. Ther 289 (1999) 66
24. Nozaki Y., Kusuhara H., Endou H., and Sugiyama Y. J. Pharmacol. Exp. Ther 309 (2004) 226
25. Naggar H., Fei Y.-J., Ganapathy V., and Smith S.B. Exp. Eye Res 77 (2003) 687
26. Li T., Tomimatsu T., Ito K., and Horie T. Life Sci 73 (2003) 2631
27. Matherly L., and Goldman D. Vitam. Horm 66 (2003) 403
28. Ganapathy V., Smith S., and Prasad P. Pflügers Archiv. Eur. J. Physiol 447 (2004) 641
29. Goldman I., and Zhao R. Semin. Oncol 6 (2002) 3
30. Nozawa T., Sugiura S., Nakajima M., Goto A., Yokoi T., Nezu J., Tsuji A., and Tamai I. Drug Met. Disp 32 (2004) 291
31. Nishizato Y., Ieiri I., Suzuki H., Kimura M., Kawabata K., Hirota T., Takane H., Irie S., Kusuhara H., and Urasaki Y. Clin. Pharmacol. Ther 73 (2003) 554
32. Briz O., Serrano M., MacIas R., Gonzalez-Gallego J., and Marin J. Biochem. J 371 (2003) 897
33. Dean M., Hamon Y., and Chimini G. J. Lipid Res 42 (2001) 1007
34. Leonard G., Fojo T., and Bates S. Oncologist 8 (2003) 411
35. Chan L.M.S., Lowes S., and Hirst B.H. Eur. J. Pharm. Sci 21 (2004) 25
36. Kruh G., and Belinsky M. Oncogene 22 (2003) 7537
37. Rea P.A. J. Exp. Bot 50 (1999) 895
38. Hoffmeyer S., Burk O., von Richter O., Arnold H.P., Brockmoller J., Johne A., Cascorbi I., Gerloff T., Roots I., Eichelbaum M., and Brinkmann U. Proc. Natl Acad. Sci. USA 97 (2000) 3473
39. Kerb R., Hoffmeyer S., and Brinkmann U. Pharmacogenomics 2 (2001) 1
40. Saito S., Iida A., Sekine A., Miura Y., Ogawa C., Kawauchi S., Higuchi S., and Nakamura Y. J. Human Gen 47 (2002) 147
41. Siddiqui A., Kerb R., Weale M., Brinkmann U., Smith A., Goldstein D., Wood N., and Sisodiya S. N. Engl. J. Med 348 (2003) 1480
42. Imai Y., Nakane M., Kage K., Tsukahara S., Ishikawa E., Tsuruo T., Miki Y., and Sugimoto Y. Mol. Cancer Ther 1 (2002) 611
43. http://nutrigene.4t.com/humanabc.htm.
44. Tsuruoka S., Ishibashi K., Yamamoto H., Wakaumi M., Suzuki M., Schwartz G., Imai M., and Fujimura A. Biochem. Biophys. Res. Commun 298 (2002) 41
45. Ford J.M., and Hait W.N. Pharmacol. Rev 42 (1990) 155
46. Dai H., Marbach P., Lemaire M., Hayes M., and Elmquist W.F. J. Pharmacol. Exp. Ther 304 (2003) 1085
47. Cvetkovic M., Leake B., Fromm M., Wilkinson G., and Kim R. Drug Met. Dispos 27 (1999) 866
48. Lecureur V., Sun D., Schuetz E., and Schuetz J. Hepatology 28 (2000) 1477
49. Lecureur V., Sun D., Hargrove P., Schuetz E.G., Kim R.B., Lan L.-B., and Schuetz J.D. Mol. Pharmacol 57 (2000) 24
50. C.G. Haimeur A., Deeley R.G., and Cole S.P. Curr. Drug Metab 5 (2004) 21
51. Keppler D., Kamisako T., Leier I., Cui Y., Nies A.T., Tsujii H., and Konig J. Adv. Enzyme Reg 40 (2000) 339
52. Huisman M.T., Smit J.W., Crommentuyn K., Zelcer N., Wiltshire H., Beijenen J.H., and Schinkel A.H. AIDS 16 (2002) 2295
53. Pratt S.E., Emerick R., Horwitz L., Gallery M., Lesoon A., Jink S., Chen V.J., and Dantzig A.H. AACR 43 (2002)
54. Kiuchi Y., Suzuki H., Hirohashi T., Tyson C.A., and Sugiyama Y. FEBS Lett 433 (1998) 149
55. Kruh G., Zeng H., Rea P., Liu G., Chen Z., Lee K., and Belinsky M. J. Bioenerg. Biomemb 33 (2001) 493
56. Sampath J., Adachi M., Hatse S., Naesens L., Balzarini J., Flatley R., Matherly L., and Schuetz J. AAPS PharmSci 4 (2002) E14
57. Schuetz J.D., Connelly M.C., Sun D.X., Paibir S.G., Flynn P.M., Srinivas R.V., Kumar A., and Fridland A. Nat. Med 5 (1999) 1048
58. Wielinga P., Reid G., Challa E., van der Heijden I., van Deemter L., de Haas M., Mol C., Kuil A., Groeneveld E., Schuetz J., Brouwer C., De Abreu R., Wijnholds J., Beijnen J., and Borst P. Mol. Pharmacol 62 (2002) 1321
59. Wielinga P., van der Heijden I., Reid G., Beijnen J., Wijnholds J., and Borst P. J. Biol. Chem 278 (2003) 17664
60. Jedlitschky G., Burchell B., and Keppler D. J. Biol. Chem 275 (2000) 30069
61. Guo Y., Kotova E., Chen Z., Lee K., Hopper-Borge E., Belinsky M., and Kruh G. J. Biol. Chem 278 (2003) 29509
62. Bera T., Lee S., Salvatore G., Lee B., and Pastan I. Mol. Med 7 (2001) 509
63. Bates S.E., Robey R., Miyake K., Rao K., Ross D.D., and Litman T. J. Bioenerg. Biomemb 33 (2001) 503
64. Janvilisri T., Venter H., Shahi S., Reuter G., Balakrishnan L., and van Veen H.W. J. Biol. Chem 278 (2003) 20645
65. Jonker J.W., Marije Buitelaar M., Wagenaar E., van der Valk M.A., Scheffer G.L., Scheper R.J., Plösch T., Kuipers F., Oude Elferink R.P.J., Rosing H., Beijnen J.H., and Schinkel A.H. Proc. Natl Acad. Sci. USA 99 (2002) 15649-15654
66. Wang X., Furukawa T., Nitanda T., Okamoto M., Sugimoto Y., Akiyama S., and Baba M. Mol. Pharmacol 63 (2003) 65
67. Valdes R., Ortega M., Casado F., Felipe A., Gil A., Sanchez-Pozo A., and Pastor-Anglada M. Gastroenterology 119 (2000) 1623
68. Adibi S.A. Am. J. Physiol. Gastrointest. Liver Physiol 285 (2003) G779
69. Erickson R.H., Gum Jr. J.R., Lindstrom M.M., McKean D., and Kim Y.S. Biochem. Biophys. Res. Commun 216 (1995) 249
70. Ayrton A., and Morgan P. Xenobiotica 31 (2001) 469
71. Bergan T. Drugs 34 (1987) 89
72. Nightingale C., Greene D.S., and Quintiliani R. J. Pharm. Sci 64 (1975) 1899
73. Meerum Terwogt J., Malingre M., Beijnen J., ten Bokkel Huinink W., Rosing H., Koopman F., van Tellingen O., Swart M., and Schellens J. Clin. Cancer Res 5 (1999) 3379
74. Spahn-Langguth H., Baktir G., Radschuweit A., Okyar A., Terhaag B., Ader P., Hanafy A., and Langguth P. Int. J. Clin. Pharm. Ther 36 (1998) 16
75. Kast H., Goodwin B., Tarr P., Jones S., Anisfeld A., Stoltz C., Tontonoz P., Kliewer S., Willson T., and Edwards P. J. Biol. Chem 277 (2002) 2908
76. Payen L., Sparfel L., Courtois A., Vernhet L., Guillouzo A., and Fardel O. Cell Biol. Toxicol 18 (2002) 221
77. Kullak-Ublick G., and Becker M. Drug Metab. Rev 35 (2003) 305
78. Westphal K., Weinbrenner A., Zschiesche M., Franke G., Knoke M., Oertel R., Fritz P., von Richter O., Warzok R., Hachenberg T., Kauffmann H., Schrenk D., Terhaag B., Kroemer H., and Siegmund W. Clin. Pharmacol. Ther 68 (2000) 345
79. Greiner B., Eichelbaum M., Fritz P., Kreichgauer H.P., von Richter O., Zundler J., and Kroemer H.K. J. Clin. Invest 104 (1999) 147
80. Kruijtzer C.M., Beijnen J.H., Rosing H., Bokkel Huinink W.W., Schot M., Jewell R.C., Paul E.M., and Schellens J.H. J. Clin. Oncol 20 (2002) 2943
81. Inui K., Masuda S., and Saito H. Kidney Int 58 (2000) 944
82. Massarella J.W., Nazareno L.A., Passe S., and Min B. Pharm. Res 13 (1996) 449
83. Somogyi A. Clin. Exp. Pharmacol. Physiol 23 (1996) 986
84. Sekine T., Cha S.H., Kanai Y., and Endou H. Clin. Exp. Nephrol 3 (1999)
85. Khamdang S., Takeda M., Babu E., Noshiro R., Onozato M., Tojo A., Enomoto A., Huang X.-L., Narikawa S., Anzai N., Piyachaturawat P., and Endou H. Eur. J. Pharmacol 465 (2003) 1
86. Sun H., Dai H., Shaik N., and Elmquist W. Adv. Drug Deliv. Rev 55 (2003) 83
87. Cooray H., Blackmore C., Maskell L., and Barrand M. NeuroReport 13 (2002) 2059
88. Fricker G., and Miller D. Pharmacology 70 (2004) 169
89. Pardridge W.M. Diabetologia 20 suppl. (1981) 246
90. Chikhale E.G., Ng K.Y., Burton P.S., and Borchardt R.T. Pharm. Res 11 (1994) 412
91. Chikhale E.G., Burton P.S., and Borchardt R.T. J. Pharmacol. Exp. Ther 273 (1995) 298
92. Levin V.A. J. Med. Chem 23 (1980) 682
93. Thiebaut F., Tsuruo T., Hamada H., Gottesman M.M., Pastan I., and Willingham M.C. J. Histochem. Cytochem 37 (1989) 159
94. Cordon-Cardo C., O'Brien J.P., Casals D., Rittman-Grauer L., Biedler J.L., Melamed M.R., and Bertino J.R. Proc. Natl Acad. Sci. USA 86 (1989) 695
95. Mahar Doan K., Humphreys J., Webster L., Wring S., Shampine L., Serabjit-Singh C., Adkison K., and Polli J. J. Pharmacol. Exp. Ther 303 (2002) 1029
96. Kemper E., van Zandbergen A., Cleypool C., Mos H., Boogerd W., Beijnen J., and van Tellingen O. Clin. Cancer Res 9 (2003) 2849
97. E. Kemper, C. Cleypool, W. Boogerd, J. Beijnen and O. Van Tellingen, Cancer Chemother. Pharmacol., 2003.
98. Sadeque A.J., Wandel C., He H., Shah S., and Wood A.J. Clin. Pharmacol. Ther 68 (2000) 231
99. Schinkel A.H., Wangenaar E., Mol C.A., and van Deemter L. J. Clin. Invest 97 (1996) 2517
100. Borst P., and Elferink R. Annu. Rev. Biochem 71 (2002) 537
101. Jedlitschky G., and Keppler D. Vitam. Horm 64 (2002) 153
102. Schuetz E.G., Strom S., Yasuda K., Lecureur V., Assem M., Brimer C., Lamba J., Kim R.B., Ramachandran V., Komoroski B.J., Venkataramanan R., Cai H., Sinal C.J., Gonzalez F.J., and Schuetz J.D. J. Biol. Chem 276 (2001) 39411
103. Kim R. Eur. J. Clin. Inv 33 (2003) 1
104. Nozawa T., Nakajima M., Tamai I., Noda K., Nezu J., Sai Y., Tsuji A., and Yokoi T. J. Pharmacol. Exp. Ther 302 (2002) 804
105. Hedman A., Angelin B., Arvidsson A., Beck O., Dahlqvist R., Nilsson B., Olsson M., and Schenck-Gustafsson K. Clin. Pharmacol. Ther 49 (1991) 256
106. Schuetz E.G., Schimkel A.H., Relling M.V., and Schuetz J.D. Proc. Natl Acad. Sci. USA 93 (1996) 4001
107. Schuetz E., Lan L., Yasuda K., Kim R., Kocarek T., Schuetz J., and Strom S. Mol. Pharmacol 62 (2002) 439