-
1
-
-
0027978907
-
Coronary artery disease regression: Convincing evidence for the benefit of aggressive lipoprotein management
-
Superko HR, Krauss MR. Coronary artery disease regression: convincing evidence for the benefit of aggressive lipoprotein management. Circulation 1994; 90: 1056-69
-
(1994)
Circulation
, vol.90
, pp. 1056-1069
-
-
Superko, H.R.1
Krauss, M.R.2
-
2
-
-
0029650740
-
Cholesterol reduction in cardiovascular disease: Clinical benefits and possible mechanisms
-
Levine GN, Keaney Jr JF, Vita JA. Cholesterol reduction in cardiovascular disease: clinical benefits and possible mechanisms. N Engl J Med 1995; 332: 512-21
-
(1995)
N Engl J Med
, vol.332
, pp. 512-521
-
-
Levine, G.N.1
Keaney J.F., Jr.2
Vita, J.A.3
-
3
-
-
0029114925
-
Lipid lowering, regression, and coronary events: A review of the interdisciplinary council on lipids and cardiovascular risk intervention, Seventh Council meeting
-
Gotto AM. Lipid lowering, regression, and coronary events: a review of the interdisciplinary council on lipids and cardiovascular risk intervention, Seventh Council meeting. Circulation 1995; 92: 647-56
-
(1995)
Circulation
, vol.92
, pp. 647-656
-
-
Gotto, A.M.1
-
4
-
-
0027322448
-
Lipid lowering and plaque regression: New insights into prevention of plaque disruption and clinical events in coronary disease
-
Brown BG, Zhao XQ, Sacco DE, et al. Lipid lowering and plaque regression: new insights into prevention of plaque disruption and clinical events in coronary disease. Circulation 1993; 87: 1781-91
-
(1993)
Circulation
, vol.87
, pp. 1781-1791
-
-
Brown, B.G.1
Zhao, X.Q.2
Sacco, D.E.3
-
5
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
Pedersen TR, Kjekshus J, Berg K, et al. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-9
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
Pedersen, T.R.1
Kjekshus, J.2
Berg, K.3
-
6
-
-
0028883828
-
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
-
West of Scotland Coronary Prevention Study Group
-
Shepherd J, Cobbe SM, Ford I, et al. West of Scotland Coronary Prevention Study Group. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995; 333: 1301-7
-
(1995)
N Engl J Med
, vol.333
, pp. 1301-1307
-
-
Shepherd, J.1
Cobbe, S.M.2
Ford, I.3
-
7
-
-
0342981862
-
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
-
Sacks FM, Pfeffer MA, Lemeul AM, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 1996; 335: 1001-9
-
(1996)
N Engl J Med
, vol.335
, pp. 1001-1009
-
-
Sacks, F.M.1
Pfeffer, M.A.2
Lemeul, A.M.3
-
8
-
-
0032572086
-
Primary prevention of acute coronary events in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study
-
Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA 1998; 279: 1615-22
-
(1998)
JAMA
, vol.279
, pp. 1615-1622
-
-
Downs, J.R.1
Clearfield, M.2
Weis, S.3
-
9
-
-
0033984125
-
The evolving role of statins in the management of atherosclerosis
-
Vaughan CJ, Gotto Jr AM, Basson CT. The evolving role of statins in the management of atherosclerosis. J Am Coll Cardiol 1999; 35: 1-10
-
(1999)
J Am Coll Cardiol
, vol.35
, pp. 1-10
-
-
Vaughan, C.J.1
Gotto A.M., Jr.2
Basson, C.T.3
-
10
-
-
0031736655
-
Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: Are the statins mechanistically similar?
-
Christians U, Jacobsen W, Floren LC. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar? Pharmacol Ther 1998; 80: 1-34
-
(1998)
Pharmacol Ther
, vol.80
, pp. 1-34
-
-
Christians, U.1
Jacobsen, W.2
Floren, L.C.3
-
11
-
-
0032805692
-
New insights into the pharmacodynamic and pharmacokinetic properties of statins
-
Corsini A, Bellosta S, Baetta R, et al. New insights into the pharmacodynamic and pharmacokinetic properties of statins. Pharmacol Ther 1999; 84: 413-28
-
(1999)
Pharmacol Ther
, vol.84
, pp. 413-428
-
-
Corsini, A.1
Bellosta, S.2
Baetta, R.3
-
12
-
-
0035980169
-
Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis
-
Aug 31
-
Ni W, Egashira K, Kataoka C, et al. Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis. Circ Res 2001 Aug 31; 89 (5): 415-21
-
(2001)
Circ Res
, vol.89
, Issue.5
, pp. 415-421
-
-
Ni, W.1
Egashira, K.2
Kataoka, C.3
-
13
-
-
12644301168
-
Multiple-dose pharmacokinetics, pharmacodynamics, and safety of atorvastatin, an inhibitor of HMG-CoA reductase, in healthy subjects
-
Dec
-
Cilla Jr DD, Whitfield LR, Gibson DM, et al. Multiple-dose pharmacokinetics, pharmacodynamics, and safety of atorvastatin, an inhibitor of HMG-CoA reductase, in healthy subjects. Clin Pharmacol Ther 1996 Dec; 60 (6): 687-95
-
(1996)
Clin Pharmacol Ther
, vol.60
, Issue.6
, pp. 687-695
-
-
Cilla D.D., Jr.1
Whitfield, L.R.2
Gibson, D.M.3
-
14
-
-
0032930330
-
Surface activity of fluvastatin and concentration dependent intestinal permeability in the rat
-
Lindahl A, Ungell A-L, Persson B, et al. Surface activity of fluvastatin and concentration dependent intestinal permeability in the rat. Pharm Res 1999; 16: 97-102
-
(1999)
Pharm Res
, vol.16
, pp. 97-102
-
-
Lindahl, A.1
Ungell, A.-L.2
Persson, B.3
-
16
-
-
0027434229
-
The interconversion kinetics, equilibrium and solubilities of the lactone and hydroxyacid forms of the HMG-CoA reductase inhibitor, CI-981
-
Kearney AS, Crawford LF, Metha SC, et al. The interconversion kinetics, equilibrium and solubilities of the lactone and hydroxyacid forms of the HMG-CoA reductase inhibitor, CI-981. Pharm Res 1993; 10: 1461-5
-
(1993)
Pharm Res
, vol.10
, pp. 1461-1465
-
-
Kearney, A.S.1
Crawford, L.F.2
Metha, S.C.3
-
17
-
-
0035111913
-
A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro
-
Ishigami M, Honda T, Takasaki W, et al. A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro. Drug Metab Dispos 2001; 29: 282-8
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 282-288
-
-
Ishigami, M.1
Honda, T.2
Takasaki, W.3
-
18
-
-
0033783036
-
Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin
-
Jacobsen W, Kuhn B, Soldner A, et al. Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin. Drug Metab Dispos 2000; 28 (11): 1369-78
-
(2000)
Drug Metab Dispos
, vol.28
, Issue.11
, pp. 1369-1378
-
-
Jacobsen, W.1
Kuhn, B.2
Soldner, A.3
-
19
-
-
0036233667
-
Glucuronidation of statins in animals and humans: A novel mechanism of statin lactonization
-
Prueksaritanont T, Subramanian R, Fang X, et al. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Drug Metab Dispos 2002; 30: 505-12
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 505-512
-
-
Prueksaritanont, T.1
Subramanian, R.2
Fang, X.3
-
20
-
-
0029794595
-
Tolerance and pharmacokinetics of single-dose atorvastatin, a potent inhibitor of HMG-CoA reductase, in healthy subjects
-
Posvar EL, Radulovic LL, Cilla DD, et al. Tolerance and pharmacokinetics of single-dose atorvastatin, a potent inhibitor of HMG-CoA reductase, in healthy subjects. J Clin Pharmacol 1996; 36: 728-31
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 728-731
-
-
Posvar, E.L.1
Radulovic, L.L.2
Cilla, D.D.3
-
21
-
-
0028845878
-
Effect of food on the bioavailability of atorvastatin, an HMG-CoA reductase inhibitor
-
Radulovic LL, Cilla DD, Posvar EL, et al. Effect of food on the bioavailability of atorvastatin, an HMG-CoA reductase inhibitor. J Clin Pharmacol 1995; 35: 990-4
-
(1995)
J Clin Pharmacol
, vol.35
, pp. 990-994
-
-
Radulovic, L.L.1
Cilla, D.D.2
Posvar, E.L.3
-
22
-
-
0031886036
-
Development, validation, and interlaboratory comparison of an HMG-CoA reductase inhibition assay for quantitation of atorvastatin in plasma matrices
-
Shum YY, Huang N, Walter G, et al. Development, validation, and interlaboratory comparison of an HMG-CoA reductase inhibition assay for quantitation of atorvastatin in plasma matrices. Ther Drug Monit 1998; 20: 41-9
-
(1998)
Ther Drug Monit
, vol.20
, pp. 41-49
-
-
Shum, Y.Y.1
Huang, N.2
Walter, G.3
-
23
-
-
0001349572
-
Absolute bioavailability of atorvastatin in man
-
Gibson DM, Stern RH, Abel RB, et al. Absolute bioavailability of atorvastatin in man. Pharm Res 1997; 14: S253
-
(1997)
Pharm Res
, vol.14
-
-
Gibson, D.M.1
Stern, R.H.2
Abel, R.B.3
-
24
-
-
0032996183
-
Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry
-
Jemal M, Ouyang Z, Chen BC, et al. Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom 1999; 13: 1003-15
-
(1999)
Rapid Commun Mass Spectrom
, vol.13
, pp. 1003-1015
-
-
Jemal, M.1
Ouyang, Z.2
Chen, B.C.3
-
25
-
-
0030953045
-
Clinical pharmacokinetics and pharmacodynamics of HMG-CoA reductase inhibitors: Similarities and dissimilarities
-
Lennernäs H, Fager G. Clinical pharmacokinetics and pharmacodynamics of HMG-CoA reductase inhibitors: similarities and dissimilarities. Clin Pharmacokinet 1997; 35: 403-25
-
(1997)
Clin Pharmacokinet
, vol.35
, pp. 403-425
-
-
Lennernäs, H.1
Fager, G.2
-
26
-
-
0034770421
-
Atorvastatin: An updated review of its pharmacological properties and use in dyslipidaemia
-
Malhotra HS, Goa KL. Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia. Drugs 2001; 61: 1835-81
-
(2001)
Drugs
, vol.61
, pp. 1835-1881
-
-
Malhotra, H.S.1
Goa, K.L.2
-
27
-
-
0021169750
-
Plasma mevalonate as a measure of cholesterol synthesis in man
-
Parker TS, McNamara DJ, Brown CD, et al. Plasma mevalonate as a measure of cholesterol synthesis in man. J Clin Invest 1984; 74: 795-804
-
(1984)
J Clin Invest
, vol.74
, pp. 795-804
-
-
Parker, T.S.1
McNamara, D.J.2
Brown, C.D.3
-
28
-
-
0029043903
-
Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-Coa reductase inhibitor
-
May
-
Nawrocki JW, Weiss SR, Davidson MH, et al. Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor. Arterioscler Thromb Vasc Biol 1995 May; 15 (5): 678-82
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, Issue.5
, pp. 678-682
-
-
Nawrocki, J.W.1
Weiss, S.R.2
Davidson, M.H.3
-
29
-
-
0031979788
-
Cimetidine does not alter atorvastatin pharmacokinetics or LDL-cholesterol reduction
-
Stern RH, Gibson DM, Whitfield LR. Cimetidine does not alter atorvastatin pharmacokinetics or LDL-cholesterol reduction. Eur J Clin Pharmacol 1998; 53 (6): 475-8
-
(1998)
Eur J Clin Pharmacol
, vol.53
, Issue.6
, pp. 475-478
-
-
Stern, R.H.1
Gibson, D.M.2
Whitfield, L.R.3
-
30
-
-
0030947754
-
Atorvastatin: A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias
-
May
-
Lea AP, McTavish D. Atorvastatin: a review of its pharmacology and therapeutic potential in the management of hyperlipidaemias. Drugs 1997 May; 53 (5): 828-47
-
(1997)
Drugs
, vol.53
, Issue.5
, pp. 828-847
-
-
Lea, A.P.1
McTavish, D.2
-
31
-
-
0033673496
-
Pharmacodynamics and pharmacokinetic-pharmacodynamic relationships of atorvastatin, an HMG-CoA reductase inhibitor
-
Jun
-
Stern RH, Yang BB, Hounslow NJ, et al. Pharmacodynamics and pharmacokinetic-pharmacodynamic relationships of atorvastatin, an HMG-CoA reductase inhibitor. J Clin Pharmacol 2000 Jun; 40 (6): 616-23
-
(2000)
J Clin Pharmacol
, vol.40
, Issue.6
, pp. 616-623
-
-
Stern, R.H.1
Yang, B.B.2
Hounslow, N.J.3
-
32
-
-
0033958096
-
Action of atorvastatin in combined hyperlipidemia: Preferential reduction of cholesteryl ester transfer from HDL to VLDL1 particles
-
Jan
-
Guerin M, Lassel TS, Le Goff W, et al. Action of atorvastatin in combined hyperlipidemia: preferential reduction of cholesteryl ester transfer from HDL to VLDL1 particles. Arterioscler Thromb Vasc Biol 2000 Jan; 20 (1): 189-97
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, Issue.1
, pp. 189-197
-
-
Guerin, M.1
Lassel, T.S.2
Le Goff, W.3
-
33
-
-
0035173483
-
Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia
-
Jan
-
Joukhadar C, Klein N, Prinz M, et al. Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia. Thromb Haemost 2001 Jan; 85 (1): 47-51
-
(2001)
Thromb Haemost
, vol.85
, Issue.1
, pp. 47-51
-
-
Joukhadar, C.1
Klein, N.2
Prinz, M.3
-
34
-
-
0028948839
-
Theoretical considerations in the correlation of drug product dissolution and in vivo bioavailability: A biopharmaceutical drug classification
-
Amidon GL, Lennernäs H, Shah V, et al. Theoretical considerations in the correlation of drug product dissolution and in vivo bioavailability: a biopharmaceutical drug classification. Pharm Res 1995; 12: 413-20
-
(1995)
Pharm Res
, vol.12
, pp. 413-420
-
-
Amidon, G.L.1
Lennernäs, H.2
Shah, V.3
-
35
-
-
0034059327
-
Atorvastatin transport in the Caco-2 cell model: Contributions of P-glycoprotein and proton-monocarboxylic acid co-transporter
-
Wu X, Whitfield LR, Stewart BH. Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and proton-monocarboxylic acid co-transporter. Pharm Res 2000; 17: 209-15
-
(2000)
Pharm Res
, vol.17
, pp. 209-215
-
-
Wu, X.1
Whitfield, L.R.2
Stewart, B.H.3
-
36
-
-
0035478419
-
The drug efflux-metabolism alliance: Biochemical aspects
-
Oct 1
-
Benet LZ, Cummins CL. The drug efflux-metabolism alliance: biochemical aspects. Adv Drug Deliv Rev 2001 Oct 1; 50 Suppl. 1: S3-S11
-
(2001)
Adv Drug Deliv Rev
, vol.50
, Issue.SUPPL. 1
-
-
Benet, L.Z.1
Cummins, C.L.2
-
37
-
-
0035434397
-
Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins)
-
Aug
-
Igel M, Sudhop T, von Bergmann K. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). Eur J Clin Pharmacol 2001 Aug; 57 (5): 357-64
-
(2001)
Eur J Clin Pharmacol
, vol.57
, Issue.5
, pp. 357-364
-
-
Igel, M.1
Sudhop, T.2
Von Bergmann, K.3
-
38
-
-
0033678688
-
Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion
-
Jan
-
Boyd RA, Stern RH, Stewart BH, et al. Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein- mediated secretion. J Clin Pharmacol 2000 Jan; 40 (1): 91-8
-
(2000)
J Clin Pharmacol
, vol.40
, Issue.1
, pp. 91-98
-
-
Boyd, R.A.1
Stern, R.H.2
Stewart, B.H.3
-
39
-
-
0031445547
-
Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism
-
Dec
-
Paine MF, Khalighi M, Fisher JM, et al. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. J Pharmacol Exp Ther 1997 Dec; 283 (3): 1552-62
-
(1997)
J Pharmacol Exp Ther
, vol.283
, Issue.3
, pp. 1552-1562
-
-
Paine, M.F.1
Khalighi, M.2
Fisher, J.M.3
-
40
-
-
0030797273
-
Human jejunal effective permeability and its correlation to preclinical drug absorption models
-
Lennernäs H. Human jejunal effective permeability and its correlation to preclinical drug absorption models. J Pharm Pharmacol 1997; 49: 627-38
-
(1997)
J Pharm Pharmacol
, vol.49
, pp. 627-638
-
-
Lennernäs, H.1
-
41
-
-
0032480901
-
Correlation of human jejunal permeability (in vivo) with experimentally and theoretically derived parameters: A multivariate data analysis approach
-
Winiwarter S, Bonham N, Hallberg A, et al. Correlation of human jejunal permeability (in vivo) with experimentally and theoretically derived parameters: a multivariate data analysis approach. J Med Chem 1999; 41: 4939-49
-
(1999)
J Med Chem
, vol.41
, pp. 4939-4949
-
-
Winiwarter, S.1
Bonham, N.2
Hallberg, A.3
-
42
-
-
0029804297
-
Jejunal permeability and hepatic extraction of fluvastatin in humans
-
Lindahl A, Sandström R, Ungell A-L, et al. Jejunal permeability and hepatic extraction of fluvastatin in humans. J Clin Pharm Ther 1996; 60: 493-503
-
(1996)
J Clin Pharm Ther
, vol.60
, pp. 493-503
-
-
Lindahl, A.1
Sandström, R.2
Ungell, A.-L.3
-
43
-
-
0030870919
-
Renal dysfunction does not alter the pharmacokinetics or LDL-cholesterol reduction of atorvastatin
-
Sep
-
Stern RH, Yang BB, Horton M, et al. Renal dysfunction does not alter the pharmacokinetics or LDL-cholesterol reduction of atorvastatin. J Clin Pharmacol 1997 Sep; 37 (9): 816-9
-
(1997)
J Clin Pharmacol
, vol.37
, Issue.9
, pp. 816-819
-
-
Stern, R.H.1
Yang, B.B.2
Horton, M.3
-
44
-
-
0033009998
-
Is the role of the small intestine in first-pass metabolism overemphasized?
-
Jun
-
Lin JH, Chiba M, Baillie TA. Is the role of the small intestine in first-pass metabolism overemphasized? Pharmacol Rev 1999 Jun; 51 (2): 135-58
-
(1999)
Pharmacol Rev
, vol.51
, Issue.2
, pp. 135-158
-
-
Lin, J.H.1
Chiba, M.2
Baillie, T.A.3
-
45
-
-
0032791745
-
Metabolism and excretion of atorvastatin in rats and dogs
-
Aug
-
Black AE, Hayes RN, Roth BD, et al. Metabolism and excretion of atorvastatin in rats and dogs. Drug Metab Dispos 1999 Aug; 27 (8): 916-23
-
(1999)
Drug Metab Dispos
, vol.27
, Issue.8
, pp. 916-923
-
-
Black, A.E.1
Hayes, R.N.2
Roth, B.D.3
-
46
-
-
0027178256
-
Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat
-
Lennernäs H, Regårdh CG. Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat. Pharm Res 1993; 5: 727-31
-
(1993)
Pharm Res
, vol.5
, pp. 727-731
-
-
Lennernäs, H.1
Regårdh, C.G.2
-
47
-
-
0032823160
-
Intestinal secretion of intravenous talinolol is inhibited by luminal R-verapamil
-
Sep
-
Gramatte T, Oertel R. Intestinal secretion of intravenous talinolol is inhibited by luminal R-verapamil. Clin Pharmacol Ther 1999 Sep; 66 (3): 239-45
-
(1999)
Clin Pharmacol Ther
, vol.66
, Issue.3
, pp. 239-245
-
-
Gramatte, T.1
Oertel, R.2
-
48
-
-
0242287624
-
The correlation between rat and human small intestinal permeability to drugs with different physico-chemical properties
-
Fagerholm U, Johansson M. Lennernäs H. The correlation between rat and human small intestinal permeability to drugs with different physico-chemical properties. Pharm Res 1996; 13: 1335-41
-
(1996)
Pharm Res
, vol.13
, pp. 1335-1341
-
-
Fagerholm, U.1
Johansson, M.2
Lennernäs, H.3
-
49
-
-
0034017007
-
Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans
-
Feb
-
Chiou WL, Jeong HY, Chung SM, et al. Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans. Pharm Res 2000 Feb; 17 (2): 135-40
-
(2000)
Pharm Res
, vol.17
, Issue.2
, pp. 135-140
-
-
Chiou, W.L.1
Jeong, H.Y.2
Chung, S.M.3
-
50
-
-
0042132423
-
Expression of a multidrug-resistance gene in human tumors and tissues
-
Fojo AT, Ueda K, Slamon DJ, et al. Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci U S A 1987; 84 (1): 265-9
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, Issue.1
, pp. 265-269
-
-
Fojo, A.T.1
Ueda, K.2
Slamon, D.J.3
-
51
-
-
0036266987
-
Mechanistic studies on metabolic interactions between gemfibrozil and statins
-
Prueksaritanont T, Zhao JJ, Ma B, et al. Mechanistic studies on metabolic interactions between gemfibrozil and statins. J Pharmacol Ther 2002; 301: 1042-51
-
(2002)
J Pharmacol Ther
, vol.301
, pp. 1042-1051
-
-
Prueksaritanont, T.1
Zhao, J.J.2
Ma, B.3
-
52
-
-
0034680792
-
Polymorphic gene regulation and interindividual variation fo UDP-glucuronosyl-transferase activity in human small intestine
-
Strassburg CP, Kneip S, Topp J, et al. Polymorphic gene regulation and interindividual variation fo UDP-glucuronosyl-transferase activity in human small intestine. J Biol Chem 2000; 275: 36164-71
-
(2000)
J Biol Chem
, vol.275
, pp. 36164-36171
-
-
Strassburg, C.P.1
Kneip, S.2
Topp, J.3
-
53
-
-
0028820208
-
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
-
Wu CY, Benet LZ, Hebert MF, et al. Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine. Clin Pharmacol Ther 1995; 58 (5): 492-7
-
(1995)
Clin Pharmacol Ther
, vol.58
, Issue.5
, pp. 492-497
-
-
Wu, C.Y.1
Benet, L.Z.2
Hebert, M.F.3
-
54
-
-
0029738490
-
First-pass metabolism of midazolam by the human intestine
-
Paine MF, Shen DD, Kunze KL, et al. First-pass metabolism of midazolam by the human intestine. Clin Pharmacol Ther 1996; 60 (1): 14-24
-
(1996)
Clin Pharmacol Ther
, vol.60
, Issue.1
, pp. 14-24
-
-
Paine, M.F.1
Shen, D.D.2
Kunze, K.L.3
-
55
-
-
0024381138
-
Pharmacokinetics of felodipine in patients with liver disease
-
Regardh CG, Edgar B, Olsson R, et al. Pharmacokinetics of felodipine in patients with liver disease. Eur J Clin Pharmacol 1989; 36 (5): 473-9
-
(1989)
Eur J Clin Pharmacol
, vol.36
, Issue.5
, pp. 473-479
-
-
Regardh, C.G.1
Edgar, B.2
Olsson, R.3
-
56
-
-
0029786432
-
Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin
-
Fromm MF, Busse D, Kroemer HK, et al. Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin. Hepatology 1996; 24 (4): 796-801
-
(1996)
Hepatology
, vol.24
, Issue.4
, pp. 796-801
-
-
Fromm, M.F.1
Busse, D.2
Kroemer, H.K.3
-
57
-
-
0032786547
-
The effect of ketoconazole on jejunal permeability and CYP 3A4 metabolism of R/S-verapamil in humans
-
Sandström R, Knutson L, Knutson T, et al. The effect of ketoconazole on jejunal permeability and CYP 3A4 metabolism of R/S-verapamil in humans. Br J Clin Pharmacol 1999; 48: 180-9
-
(1999)
Br J Clin Pharmacol
, vol.48
, pp. 180-189
-
-
Sandström, R.1
Knutson, L.2
Knutson, T.3
-
58
-
-
0242645646
-
Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin
-
Aug
-
Lilja JJ, Kivisto KT, Neuvonen PJ. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 1999 Aug; 66 (2): 118-27
-
(1999)
Clin Pharmacol Ther
, vol.66
, Issue.2
, pp. 118-127
-
-
Lilja, J.J.1
Kivisto, K.T.2
Neuvonen, P.J.3
-
59
-
-
0033745108
-
Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin
-
Oct
-
Mazzu AL, Lasseter KC, Shamblen EC, et al. Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin. Clin Pharmacol Ther 2000 Oct; 68 (4): 391-400
-
(2000)
Clin Pharmacol Ther
, vol.68
, Issue.4
, pp. 391-400
-
-
Mazzu, A.L.1
Lasseter, K.C.2
Shamblen, E.C.3
-
60
-
-
0000460810
-
14C atorvastatin in patients with T-tube drainage
-
14C atorvastatin in patients with T-tube drainage [abstract]. Proc Aust Soc Clin Exp Pharmacol Toxicol 1996; 3: 153
-
(1996)
Proc Aust Soc Clin Exp Pharmacol Toxicol
, vol.3
, pp. 153
-
-
Le Couteur, D.G.1
Martin, P.F.2
Pond, S.M.3
Bracs, P.4
Black, A.5
Hayes, R.6
Woolf, T.F.7
Stern, R.8
-
61
-
-
0033943874
-
Oatp2 mediates bidirectional organic solute transport: A role for intracellular glutathione
-
Li L, Meier PJ, Ballatori N. Oatp2 mediates bidirectional organic solute transport: a role for intracellular glutathione. Mol Pharmacol 2002; 58: 335-40
-
(2002)
Mol Pharmacol
, vol.58
, pp. 335-340
-
-
Li, L.1
Meier, P.J.2
Ballatori, N.3
-
62
-
-
0028303820
-
Plasma protein binding displacement interactions - Why are they still regarded as clinically important?
-
Rolan PE. Plasma protein binding displacement interactions - why are they still regarded as clinically important? Br J Clin Pharmacol 1994; 37: 125-8
-
(1994)
Br J Clin Pharmacol
, vol.37
, pp. 125-128
-
-
Rolan, P.E.1
-
63
-
-
0025120211
-
Regulation of the mevalonate pathway
-
Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 1990; 343: 425-30
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
64
-
-
0000685377
-
Pharmacokinetics and dose proportionality of atorvastatin and its active metabolites
-
Yang BB, Smithers JA, Stern RH, Sedman AJ, Olsen SC. Pharmacokinetics and dose proportionality of atorvastatin and its active metabolites [abstract]. Pharm Res 1996; 13 Suppl 1: S437
-
(1996)
Pharm Res
, vol.13
, Issue.SUPPL. 1
-
-
Yang, B.B.1
Smithers, J.A.2
Stern, R.H.3
Sedman, A.J.4
Olsen, S.C.5
-
65
-
-
0000783041
-
Evaluation of the genetic component of variability in CYP3A4 activity: A repeated drug administration method
-
Jul
-
Ozdemir V, Kalowa W, Tang BK, et al. Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method. Pharmacogenetics 2000 Jul; 10 (5): 373-88
-
(2000)
Pharmacogenetics
, vol.10
, Issue.5
, pp. 373-388
-
-
Ozdemir, V.1
Kalowa, W.2
Tang, B.K.3
-
66
-
-
0036843479
-
Effects of fibrates on metabolism of statins in human hepatocytes
-
Prueksaritanont T, Tang C, Qiu Y, et al. Effects of fibrates on metabolism of statins in human hepatocytes. Drug Metab Dispos 2002; 30: 1280-7
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1280-1287
-
-
Prueksaritanont, T.1
Tang, C.2
Qiu, Y.3
-
67
-
-
0033601257
-
A novel human hepatic organic anion transporting polypeptide (OATP 2)
-
Hsiang B, Zhut Y, Wang Z, et al. A novel human hepatic organic anion transporting polypeptide (OATP 2). J Biol Chem 1999; 274: 37161-8
-
(1999)
J Biol Chem
, vol.274
, pp. 37161-37168
-
-
Hsiang, B.1
Zhut, Y.2
Wang, Z.3
-
68
-
-
0035012075
-
Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes
-
Nakai D, Nakagomi R, Furuta Y, et al. Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. J Pharm Exp Pharmacol 2001; 297: 861-7
-
(2001)
J Pharm Exp Pharmacol
, vol.297
, pp. 861-867
-
-
Nakai, D.1
Nakagomi, R.2
Furuta, Y.3
-
69
-
-
0002186061
-
Rosuvastatin is a high affinity substrate of hepatic organic anion transport OATP-C
-
Brown CDA, Windass A, Bleasby K, et al. Rosuvastatin is a high affinity substrate of hepatic organic anion transport OATP-C [abstract]. Artherosclerosis 2001; 2 Suppl. 2: 90
-
(2001)
Artherosclerosis
, vol.2
, Issue.SUPPL. 2
, pp. 90
-
-
Brown, C.D.A.1
Windass, A.2
Bleasby, K.3
-
70
-
-
0030005053
-
Effect of age and gender on pharmacokinetics of atorvastatin in humans
-
Gibson DM, Bron NJ, Richens A, et al. Effect of age and gender on pharmacokinetics of atorvastatin in humans. J Clin Pharmacol 1996; 36: 242-6
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 242-246
-
-
Gibson, D.M.1
Bron, N.J.2
Richens, A.3
-
71
-
-
0036881095
-
Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein
-
Cummins CL, Wu CH, Benet LZ. Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein. Clin Pharm Ther 2002; 72: 474-89
-
(2002)
Clin Pharm Ther
, vol.72
, pp. 474-489
-
-
Cummins, C.L.1
Wu, C.H.2
Benet, L.Z.3
-
72
-
-
9344235448
-
Pharmacodynamic effects and pharmacokinetics of atorvastatin after administration to normocholesterolemic subjects in the morning and evening
-
Jul
-
Cilla Jr DD, Gibson DM, Whitfield LR, et al. Pharmacodynamic effects and pharmacokinetics of atorvastatin after administration to normocholesterolemic subjects in the morning and evening. J Clin Pharmacol 1996 Jul; 36 (7): 604-9
-
(1996)
J Clin Pharmacol
, vol.36
, Issue.7
, pp. 604-609
-
-
Cilla D.D., Jr.1
Gibson, D.M.2
Whitfield, L.R.3
-
73
-
-
0038701977
-
Pharmacokinetics of atorvastatin and its metabolites after single and multiple dosing in hypercholesterolaemic haemodialysis patients
-
Lins RL, Matthys KE, Verpooten GA, et al. Pharmacokinetics of atorvastatin and its metabolites after single and multiple dosing in hypercholesterolaemic haemodialysis patients. Nephrol Dial Transplant 2003; 18 (5): 967-76
-
(2003)
Nephrol Dial Transplant
, vol.18
, Issue.5
, pp. 967-976
-
-
Lins, R.L.1
Matthys, K.E.2
Verpooten, G.A.3
-
74
-
-
0037539996
-
Characterisation of hepatic cytochrome P450 3A activity in patients with end stage renal disease
-
Dowling TC, Briglia AE, Fink JC, et al. Characterisation of hepatic cytochrome P450 3A activity in patients with end stage renal disease. Clin Pharmacol Ther 2003; 73: 427-34
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 427-434
-
-
Dowling, T.C.1
Briglia, A.E.2
Fink, J.C.3
-
75
-
-
0033679135
-
Effect of food on the pharmacodynamics and pharmacokinetics of atorvastatin, an inhibitor of HMG-CoA reductase
-
Apr-Jun
-
Whitfield LR, Stern RH, Sedman AJ, Abel R, Gibson DM. Effect of food on the pharmacodynamics and pharmacokinetics of atorvastatin, an inhibitor of HMG-CoA reductase. Eur J Drug Metab Pharmacokinet 2000 Apr-Jun; 25 (2): 97-101
-
(2000)
Eur J Drug Metab Pharmacokinet
, vol.25
, Issue.2
, pp. 97-101
-
-
Whitfield, L.R.1
Stern, R.H.2
Sedman, A.J.3
Abel, R.4
Gibson, D.M.5
-
76
-
-
0032927254
-
Drug, meal and formulation interactions influencing drug absorption after oral administration: Clinical implications
-
Mar
-
Fleisher D, Li C, Zhou Y, et al. Drug, meal and formulation interactions influencing drug absorption after oral administration: clinical implications. Clin Pharmacokinet 1999 Mar; 36 (3): 233-54
-
(1999)
Clin Pharmacokinet
, vol.36
, Issue.3
, pp. 233-254
-
-
Fleisher, D.1
Li, C.2
Zhou, Y.3
-
77
-
-
0034266349
-
HMG-CoA reductase inhibitors: Assessing differences in drug interactions and safety profiles
-
Beaird SL. HMG-CoA reductase inhibitors: assessing differences in drug interactions and safety profiles. J Am Pharm Assoc 2000; 40 (5): 637-44
-
(2000)
J Am Pharm Assoc
, vol.40
, Issue.5
, pp. 637-644
-
-
Beaird, S.L.1
-
78
-
-
0035076611
-
HMG-CoA reductase inhibitors and P-glycoprotein modulation
-
Mar
-
Bogman K, Peyer AK, Torok M, et al. HMG-CoA reductase inhibitors and P-glycoprotein modulation. Br J Pharmacol 2001 Mar; 132 (6): 1183-92
-
(2001)
Br J Pharmacol
, vol.132
, Issue.6
, pp. 1183-1192
-
-
Bogman, K.1
Peyer, A.K.2
Torok, M.3
-
79
-
-
0034866642
-
HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein
-
Jun
-
Wang E, Casciano CN, Clement RP, et al. HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein. Pharm Res 2001 Jun; 18 (6): 800-6
-
(2001)
Pharm Res
, vol.18
, Issue.6
, pp. 800-806
-
-
Wang, E.1
Casciano, C.N.2
Clement, R.P.3
-
80
-
-
0041324754
-
The effects of concurrent atorvastatin therapy on the pharmacokinetics of intravenous midazolam
-
McDonnell CG, Harte S, O'Driscoll J, et al. The effects of concurrent atorvastatin therapy on the pharmacokinetics of intravenous midazolam. Anaesthesia 2003; 58: 899-904
-
(2003)
Anaesthesia
, vol.58
, pp. 899-904
-
-
McDonnell, C.G.1
Harte, S.2
O'Driscoll, J.3
-
81
-
-
0034821958
-
Rhabdomyolysis and HMG-CoA reductase inhibitors
-
Sep
-
Omar MA, Wilson JP, Cox TS. Rhabdomyolysis and HMG-CoA reductase inhibitors. Ann Pharmacother 2001 Sep; 35 (9): 1096-107
-
(2001)
Ann Pharmacother
, vol.35
, Issue.9
, pp. 1096-1107
-
-
Omar, M.A.1
Wilson, J.P.2
Cox, T.S.3
-
82
-
-
0032743429
-
Rhabdomyolysis associated with concomitant use of atorvastatin and cyclosporine
-
Nov
-
Maltz HC, Balog DL, Cheigh JS. Rhabdomyolysis associated with concomitant use of atorvastatin and cyclosporine. Ann Pharmacother 1999 Nov; 33 (11): 1176-9
-
(1999)
Ann Pharmacother
, vol.33
, Issue.11
, pp. 1176-1179
-
-
Maltz, H.C.1
Balog, D.L.2
Cheigh, J.S.3
-
83
-
-
0034476733
-
The potential for drug interactions with statin therapy in Ireland
-
Jul-Sep
-
Heerey A, Barry M, Ryan M, Kelly A. The potential for drug interactions with statin therapy in Ireland. Ir J Med Sci 2000 Jul-Sep; 169 (3): 176-9
-
(2000)
Ir J Med Sci
, vol.169
, Issue.3
, pp. 176-179
-
-
Heerey, A.1
Barry, M.2
Ryan, M.3
Kelly, A.4
-
84
-
-
0029161742
-
Prominence of coronary arterial wall lipids in human heart allografts: Implications for pathogenesis of allograft arteriopathy
-
Aug
-
McManus BM, Horley KJ, Wilson JE, et al. Prominence of coronary arterial wall lipids in human heart allografts: implications for pathogenesis of allograft arteriopathy. Am J Pathol 1995 Aug; 147 (2): 293-308
-
(1995)
Am J Pathol
, vol.147
, Issue.2
, pp. 293-308
-
-
McManus, B.M.1
Horley, K.J.2
Wilson, J.E.3
-
85
-
-
0023929374
-
Rhabdomyolysis and renal injury with lovastatin use: Report of two cases in cardiac transplant recipients
-
Jul 8
-
Corpier CL, Jones PH, Suki WN, et al. Rhabdomyolysis and renal injury with lovastatin use: report of two cases in cardiac transplant recipients. JAMA 1988 Jul 8; 260 (2): 239-41
-
(1988)
JAMA
, vol.260
, Issue.2
, pp. 239-241
-
-
Corpier, C.L.1
Jones, P.H.2
Suki, W.N.3
-
86
-
-
0034521356
-
Rhabdomyolysis and acute renal failure in a cardiac transplant recipient due to multiple drug interactions
-
Dec
-
Kusus M, Stapleton DD, Lertora JJ, et al. Rhabdomyolysis and acute renal failure in a cardiac transplant recipient due to multiple drug interactions. Am J Med Sci 2000 Dec; 320 (6): 394-7
-
(2000)
Am J Med Sci
, vol.320
, Issue.6
, pp. 394-397
-
-
Kusus, M.1
Stapleton, D.D.2
Lertora, J.J.3
-
87
-
-
0000026430
-
Atorvastatin for refractory hypercholesterolemia in heart transplant patients
-
Kobashigawa JA, Moriguchi JD, Ro TK, et al. Atorvastatin for refractory hypercholesterolemia in heart transplant patients [abstract]. J Am Coll Cardiol 1998; 31 Suppl. A: 157A
-
(1998)
J Am Coll Cardiol
, vol.31
, Issue.SUPPL. A
-
-
Kobashigawa, J.A.1
Moriguchi, J.D.2
Ro, T.K.3
-
88
-
-
0034725821
-
Acute rhabdomyolysis after atorvastatin and fusidic acid therapy
-
Jul
-
Wenisch C, Krause R, Fladerer P, et al. Acute rhabdomyolysis after atorvastatin and fusidic acid therapy. Am J Med 2000 Jul; 109 (1): 78
-
(2000)
Am J Med
, vol.109
, Issue.1
, pp. 78
-
-
Wenisch, C.1
Krause, R.2
Fladerer, P.3
-
89
-
-
0034924212
-
Statin-fibrate combination therapy
-
Shek A, Ferrill MJ. Statin-fibrate combination therapy. Ann Pharmacother 2001; 35: 908-17
-
(2001)
Ann Pharmacother
, vol.35
, pp. 908-917
-
-
Shek, A.1
Ferrill, M.J.2
-
90
-
-
0032005257
-
Rhabdomyolysis after taking atorvastatin with gemfibrozil
-
Feb 1
-
Duell PB, Connor WE, Illingworth DR. Rhabdomyolysis after taking atorvastatin with gemfibrozil. Am J Cardiol 1998 Feb 1; 81 (3): 368-9
-
(1998)
Am J Cardiol
, vol.81
, Issue.3
, pp. 368-369
-
-
Duell, P.B.1
Connor, W.E.2
Illingworth, D.R.3
-
91
-
-
0034284534
-
Cyclosporine-drug interactions and the influence of patient age
-
Sep 1
-
Lill J, Bauer LA, Horn JR, et al. Cyclosporine-drug interactions and the influence of patient age. Am J Health Syst Pharm 2000 Sep 1; 57 (17): 1579-84
-
(2000)
Am J Health Syst Pharm
, vol.57
, Issue.17
, pp. 1579-1584
-
-
Lill, J.1
Bauer, L.A.2
Horn, J.R.3
-
92
-
-
0035185490
-
Pharmacokinetic interactions between nelfinavir and 3-hydroxy-3- methylglutaryl coenzyme a reductase inhibitors atorvastatin and simvastatin
-
Dec
-
Hsyu PH, Schultz-Smith MD, Lillibridge JH, et al. Pharmacokinetic interactions between nelfinavir and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors atorvastatin and simvastatin. Antimicrob Agents Chemother 2001 Dec; 45 (12): 3445-50
-
(2001)
Antimicrob Agents Chemother
, vol.45
, Issue.12
, pp. 3445-3450
-
-
Hsyu, P.H.1
Schultz-Smith, M.D.2
Lillibridge, J.H.3
-
93
-
-
0037040378
-
Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG study A5047
-
Fichtenbaum CJ, Gerber JG, Rosenkranz SL, et al. Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG study A5047. AIDS 2002; 16: 569-77
-
(2002)
AIDS
, vol.16
, pp. 569-577
-
-
Fichtenbaum, C.J.1
Gerber, J.G.2
Rosenkranz, S.L.3
-
94
-
-
0036472134
-
Pharmacokinetic enhancement of protease inhibitors
-
Acosta EP. Pharmacokinetic enhancement of protease inhibitors. J Acquir Immune Defic Syndr 2002; 29: S11-8
-
(2002)
J Acquir Immune Defic Syndr
, vol.29
-
-
Acosta, E.P.1
-
95
-
-
0033802285
-
Potential interaction between troglitazone and atorvastatin
-
Aug
-
DiTusa L, Luzier AB. Potential interaction between troglitazone and atorvastatin. J Clin Pharm Ther 2000 Aug; 25 (4): 279-82
-
(2000)
J Clin Pharm Ther
, vol.25
, Issue.4
, pp. 279-282
-
-
DiTusa, L.1
Luzier, A.B.2
-
96
-
-
0037386735
-
Control of steroid, heme, and cacinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor
-
Xie W, Yeuh MF, Radominska-Pandya A, et al. Control of steroid, heme, and cacinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proc Natl Acad Sci U S A 2003; 100: 4150-5
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4150-4155
-
-
Xie, W.1
Yeuh, M.F.2
Radominska-Pandya, A.3
-
97
-
-
0013663866
-
Effect of troglitazone on pharmacokinetics and pharmacodynamics of atorvastatin
-
Loi CM, Stern RH, Abel R, et al. Effect of troglitazone on pharmacokinetics and pharmacodynamics of atorvastatin [abstract]. Clin Pharmacol Ther 1999; 65: 186
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 186
-
-
Loi, C.M.1
Stern, R.H.2
Abel, R.3
-
98
-
-
0032806143
-
Erythromycin coadministration increases plasma atorvastatin concentrations
-
May
-
Siedlik PH, Olson SC, Yang BB, et al. Erythromycin coadministration increases plasma atorvastatin concentrations. J Clin Pharmacol 1999 May; 39 (5): 501-4
-
(1999)
J Clin Pharmacol
, vol.39
, Issue.5
, pp. 501-504
-
-
Siedlik, P.H.1
Olson, S.C.2
Yang, B.B.3
-
99
-
-
0029995258
-
Effects of atorvastatin, an HMG-CoA reductase inhibitor, on hepatic oxidative metabolism of amipyrine
-
Apr
-
Yang BB, Hounslow NJ, Sedman AJ, et al. Effects of atorvastatin, an HMG-CoA reductase inhibitor, on hepatic oxidative metabolism of amipyrine. J Clin Pharmacol 1996 Apr; 36 (4): 356-60
-
(1996)
J Clin Pharmacol
, vol.36
, Issue.4
, pp. 356-360
-
-
Yang, B.B.1
Hounslow, N.J.2
Sedman, A.J.3
-
100
-
-
0035165026
-
Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients
-
Jan
-
Renders L, Mayer-Kadner I, Koch C, et al. Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients. Nephrol Dial Transplant 2001 Jan; 16 (1): 141-6
-
(2001)
Nephrol Dial Transplant
, vol.16
, Issue.1
, pp. 141-146
-
-
Renders, L.1
Mayer-Kadner, I.2
Koch, C.3
-
101
-
-
0031865236
-
Atorvastatin does not produce a clinically significant effect on the pharmacokinetics of terfenadine
-
Aug
-
Stern RH, Smithers JA, Olson SC. Atorvastatin does not produce a clinically significant effect on the pharmacokinetics of terfenadine. J Clin Pharmacol 1998 Aug; 38 (8): 753-7
-
(1998)
J Clin Pharmacol
, vol.38
, Issue.8
, pp. 753-757
-
-
Stern, R.H.1
Smithers, J.A.2
Olson, S.C.3
-
102
-
-
0034428256
-
Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P450 enzymes
-
Dec
-
Cohen LH, van Leeuwen RE, van Thiel GC, et al. Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P450 enzymes. Biopharm Drug Dispos 2000 Dec; 21 (9): 353-64
-
(2000)
Biopharm Drug Dispos
, vol.21
, Issue.9
, pp. 353-364
-
-
Cohen, L.H.1
Van Leeuwen, R.E.2
Van Thiel, G.C.3
-
103
-
-
0035107449
-
The effect of rifampin administration on the disposition of fexofenadine
-
Mar
-
Hamman MA, Bruce MA, Haehner-Daniels BD, et al. The effect of rifampin administration on the disposition of fexofenadine. Clin Pharmacol Ther 2001 Mar; 69 (3): 114-21
-
(2001)
Clin Pharmacol Ther
, vol.69
, Issue.3
, pp. 114-121
-
-
Hamman, M.A.1
Bruce, M.A.2
Haehner-Daniels, B.D.3
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