-
1
-
-
0040368659
-
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
-
T. Abe M. Kakyo T. Tokui R. Nakagomi T. Nishio D. Nakai H. Nomura M. Unno M. Suzuki T. Naitoh S. Matsuno H. Yawo Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1 J. Biol. Chem. 274 1999 17159 17163
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17159-17163
-
-
Abe, T.1
Kakyo, M.2
Tokui, T.3
Nakagomi, R.4
Nishio, T.5
Nakai, D.6
Nomura, H.7
Unno, M.8
Suzuki, M.9
Naitoh, T.10
Matsuno, S.11
Yawo, H.12
-
2
-
-
0025861580
-
ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver
-
T.P. Akerboom V. Narayanaswami M. Kunst H. Sies ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver J. Biol. Chem. 266 1991 13147 13152
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 13147-13152
-
-
Akerboom, T.P.1
Narayanaswami, V.2
Kunst, M.3
Sies, H.4
-
3
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
S.V. Ambudkar S Dey C.A. Hrycyna M. Ramachandra I. Pastan M.M. Gottesman Biochemical, cellular, and pharmacological aspects of the multidrug transporter Annu. Rev. Pharmacol. Toxicol. 39 1999 361 398
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
5
-
-
0033610801
-
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain
-
E. Bakos R. Evers G. Szakacs G.E. Tusnady E. Welker K. Szabo M. de Haas L. van Deemter P. Borst A. Varadi B. Sarkadi Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain J. Biol. Chem. 273 1998 32167 32175
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32167-32175
-
-
Bakos, E.1
Evers, R.2
Szakacs, G.3
Tusnady, G.E.4
Welker, E.5
Szabo, K.6
de Haas, M.7
van Deemter, L.8
Borst, P.9
Varadi, A.10
Sarkadi, B.11
-
7
-
-
0027473114
-
Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein
-
M.A. Barrand T. Rhodes M.S. Center P.R. Twentyman Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein Eur. J. Cancer 29A 1993 408 415
-
(1993)
Eur. J. Cancer
, vol.29A
, pp. 408-415
-
-
Barrand, M.A.1
Rhodes, T.2
Center, M.S.3
Twentyman, P.R.4
-
9
-
-
0027429147
-
Differential inhibition by cyclosporins of primary-active ATP-dependent transporters in the hepatocyte canalicular membrane
-
M. Böhme M. Büchler M. Müller D. Keppler Differential inhibition by cyclosporins of primary-active ATP-dependent transporters in the hepatocyte canalicular membrane FEBS Lett. 333 1993 193 196
-
(1993)
FEBS Lett.
, vol.333
, pp. 193-196
-
-
Böhme, M.1
Büchler, M.2
Müller, M.3
Keppler, D.4
-
10
-
-
0034674901
-
A family of drug transporters: The multidrug resistance-associated proteins
-
P. Borst R. Evers M. Kool J. Wijnholds A family of drug transporters: The multidrug resistance-associated proteins J. Natl. Cancer Inst. 92 2000 1295 1302
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1295-1302
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
11
-
-
0040761368
-
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMRP, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
-
M. Büchler J. König M. Brom J. Kartenbeck H. Spring T. Horie D. Keppler cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMRP, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats J. Biol. Chem. 271 1996 15091 15098
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15091-15098
-
-
Büchler, M.1
König, J.2
Brom, M.3
Kartenbeck, J.4
Spring, H.5
Horie, T.6
Keppler, D.7
-
12
-
-
0033998261
-
MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells
-
T. Cantz A.T. Nies M. Brom A.F. Hofmann D. Keppler MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells Am. J. Physiol. 278 2000 G522 G531
-
(2000)
Am. J. Physiol.
, vol.278
, pp. G522-G531
-
-
Cantz, T.1
Nies, A.T.2
Brom, M.3
Hofmann, A.F.4
Keppler, D.5
-
13
-
-
0027945466
-
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
-
X.S. Chen J.R. Sheller E.N. Johnson C.D. Funk Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene Nature 372 1994 179 182
-
(1994)
Nature
, vol.372
, pp. 179-182
-
-
Chen, X.S.1
Sheller, J.R.2
Johnson, E.N.3
Funk, C.D.4
-
14
-
-
0030959378
-
Multispecific organic anion transporter is responsible for the biliary excretion of the camptothecin derivative irinotecan and its metabolites in rats
-
X.Y. Chu Y. Kato K. Niinuma K.I. Sudo H. Hakusui Y. Sugiyama Multispecific organic anion transporter is responsible for the biliary excretion of the camptothecin derivative irinotecan and its metabolites in rats J. Pharmacol. Exp. Ther. 281 1997 304 314
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 304-314
-
-
Chu, X.Y.1
Kato, Y.2
Niinuma, K.3
Sudo, K.I.4
Hakusui, H.5
Sugiyama, Y.6
-
15
-
-
0025099593
-
Alterations in glutathione and glutathione-related enzymes in a multidrug-resistant small cell lung cancer cell line
-
S.P. Cole H.F. Downes S.E. Mirski D.J. Clements Alterations in glutathione and glutathione-related enzymes in a multidrug-resistant small cell lung cancer cell line Mol. Pharmacol. 37 1990 192 197
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 192-197
-
-
Cole, S.P.1
Downes, H.F.2
Mirski, S.E.3
Clements, D.J.4
-
16
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
S.P. Cole G. Bhardwaj J.H. Gerlach J.E. Mackie C.E. Grant K.C. Almquist A.J. Stewart E.U. Kurz A.M. Duncan R.G. Deeley Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line Science 258 1992 1650 1654
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Duncan, A.M.9
Deeley, R.G.10
-
17
-
-
0345299165
-
Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells
-
Y. Cui J. König U. Buchholz H. Spring I. Leier D. Keppler Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells Mol. Pharmacol. 55 1999 929 937
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 929-937
-
-
Cui, Y.1
König, J.2
Buchholz, U.3
Spring, H.4
Leier, I.5
Keppler, D.6
-
18
-
-
0035971239
-
Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6
-
Y. Cui J. König I. Leier U. Buchholz D. Keppler Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6 J. Biol. Chem. 276 2001 9626 9630
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9626-9630
-
-
Cui, Y.1
König, J.2
Leier, I.3
Buchholz, U.4
Keppler, D.5
-
21
-
-
0031053478
-
Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein
-
M.P. Draper R.L. Martell S.B. Levy Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein Br. J. Cancer 75 1997 810 815
-
(1997)
Br. J. Cancer
, vol.75
, pp. 810-815
-
-
Draper, M.P.1
Martell, R.L.2
Levy, S.B.3
-
22
-
-
0024329881
-
The biochemistry of P-glycoprotein-mediated multidrug resistance
-
J.A. Endicott V. Ling The biochemistry of P-glycoprotein-mediated multidrug resistance Annu. Rev. Biochem. 58 1989 137 171
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 137-171
-
-
Endicott, J.A.1
Ling, V.2
-
23
-
-
0029995238
-
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells
-
R. Evers G.J. Zaman L. van Deemter H. Jansen J. Calafat L.C. Oomen R.P. Oude Elferink P. Borst A.H. Schinkel Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells J. Clin. Invest. 97 1996 1211 1218
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1211-1218
-
-
Evers, R.1
Zaman, G.J.2
van Deemter, L.3
Jansen, H.4
Calafat, J.5
Oomen, L.C.6
Oude Elferink, R.P.7
Borst, P.8
Schinkel, A.H.9
-
25
-
-
0001308329
-
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA
-
R. Evers M. Kool L. van Deemter H. Janssen J. Calafat L.C. Oomen C.C. Paulusma R.P. Oude Elferink F. Baas A.H. Schinkel P. Borst Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA J. Clin. Invest. 101 1998 1310 1319
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1310-1319
-
-
Evers, R.1
Kool, M.2
van Deemter, L.3
Janssen, H.4
Calafat, J.5
Oomen, L.C.6
Paulusma, C.C.7
Oude Elferink, R.P.8
Baas, F.9
Schinkel, A.H.10
Borst, P.11
-
28
-
-
9244261944
-
Tissue distribution of the multidrug resistance protein
-
M.J. Flens G.J. Zaman P. van der Valk M.A. Izquierdo A.B. Schroeijers G.L. Scheffer P. van der Groep M. de Haas C.J. Meijer R.J. Scheper Tissue distribution of the multidrug resistance protein Am. J. Pathol. 148 1996 1237 1247
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1237-1247
-
-
Flens, M.J.1
Zaman, G.J.2
van der Valk, P.3
Izquierdo, M.A.4
Schroeijers, A.B.5
Scheffer, G.L.6
van der Groep, P.7
de Haas, M.8
Meijer, C.J.9
Scheper, R.J.10
-
30
-
-
0028857378
-
The specific bisindolylmaleimide PKC-inhibitor GF 109203X efficiently modulates MRP-associated multiple drug resistance
-
V. Gekeler R. Boer W. Ise K.H. Sanders C. Schachtele J. Beck The specific bisindolylmaleimide PKC-inhibitor GF 109203X efficiently modulates MRP-associated multiple drug resistance Biochem. Biophys. Res. Commun. 206 1995 119 126
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.206
, pp. 119-126
-
-
Gekeler, V.1
Boer, R.2
Ise, W.3
Sanders, K.H.4
Schachtele, C.5
Beck, J.6
-
31
-
-
0031041043
-
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP
-
U.A. Germann P.J. Ford D. Shlyakhter V.S. Mason M.W. Harding Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP Anticancer Drugs 8 1997 141 155
-
(1997)
Anticancer Drugs
, vol.8
, pp. 141-155
-
-
Germann, U.A.1
Ford, P.J.2
Shlyakhter, D.3
Mason, V.S.4
Harding, M.W.5
-
32
-
-
0029124936
-
Difloxacin reverses multidrug resistance in HL-60/AR cells that overexpress the multidrug resistance-related protein (MRP) gene
-
S. Gollapudi F. Thadepalli C.H. Kim S. Gupta Difloxacin reverses multidrug resistance in HL-60/AR cells that overexpress the multidrug resistance-related protein (MRP) gene Oncol. Res. 7 1995 213 225
-
(1995)
Oncol. Res.
, vol.7
, pp. 213-225
-
-
Gollapudi, S.1
Thadepalli, F.2
Kim, C.H.3
Gupta, S.4
-
33
-
-
0030953774
-
Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells
-
S. Gollapudi C.H. Kim B.N. Tran S. Sangha S. Gupta Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells Cancer Chemother. Pharmacol. 40 1997 150 158
-
(1997)
Cancer Chemother. Pharmacol.
, vol.40
, pp. 150-158
-
-
Gollapudi, S.1
Kim, C.H.2
Tran, B.N.3
Sangha, S.4
Gupta, S.5
-
34
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
M.M. Gottesman I. Pastan Biochemistry of multidrug resistance mediated by the multidrug transporter Annu. Rev. Biochem. 62 1993 385 427
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
36
-
-
0028054888
-
Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs
-
C.E. Grant G. Valdimarsson D.R. Hipfner K.C. Almquist S. Cole R.G. Deeley Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs Cancer Res. 54 1994 357 361
-
(1994)
Cancer Res.
, vol.54
, pp. 357-361
-
-
Grant, C.E.1
Valdimarsson, G.2
Hipfner, D.R.3
Almquist, K.C.4
Cole, S.5
Deeley, R.G.6
-
37
-
-
0030726443
-
Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA
-
C.E. Grant E.U. Kurz S.P. Cole R.G. Deeley Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA Genomics 45 1997 368 378
-
(1997)
Genomics
, vol.45
, pp. 368-378
-
-
Grant, C.E.1
Kurz, E.U.2
Cole, S.P.3
Deeley, R.G.4
-
38
-
-
0029044441
-
Noninvasive assessment of hepatobiliary and renal elimination of cysteinyl leukotrienes by positron emission tomography
-
A. Guhlmann K. Krauss F. Oberdorfer T. Siegel P.H. Scheuber J. Muller B. Csuk-Glanzer S. Ziegler H. Ostertag D. Keppler Noninvasive assessment of hepatobiliary and renal elimination of cysteinyl leukotrienes by positron emission tomography Hepatology 21 1995 1568 1575
-
(1995)
Hepatology
, vol.21
, pp. 1568-1575
-
-
Guhlmann, A.1
Krauss, K.2
Oberdorfer, F.3
Siegel, T.4
Scheuber, P.H.5
Muller, J.6
Csuk-Glanzer, B.7
Ziegler, S.8
Ostertag, H.9
Keppler, D.10
-
41
-
-
0033591235
-
Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3)
-
T. Hirohashi H. Suzuki Y. Sugiyama Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3) J. Biol. Chem. 274 1999 15181 15185
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15181-15185
-
-
Hirohashi, T.1
Suzuki, H.2
Sugiyama, Y.3
-
42
-
-
0038224010
-
SRS-A to Leukotrienes, The Dawning of a New Treatment
-
S. Holgate S.E. Dahlén SRS-A to Leukotrienes, The Dawning of a New Treatment 1997 Blackwell Science Oxford
-
(1997)
-
-
Holgate, S.1
Dahlén, S.E.2
-
44
-
-
0033152212
-
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2
-
J.H. Hooijberg H.J. Broxterman M. Kool Y.G. Assaraf G.J. Peters P. Noordhuis R.J. Scheper P. Borst H.M. Pinedo G. Jansen Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2 Cancer Res. 59 1999 2532 2535
-
(1999)
Cancer Res.
, vol.59
, pp. 2532-2535
-
-
Hooijberg, J.H.1
Broxterman, H.J.2
Kool, M.3
Assaraf, Y.G.4
Peters, G.J.5
Noordhuis, P.6
Scheper, R.J.7
Borst, P.8
Pinedo, H.M.9
Jansen, G.10
-
45
-
-
0033601257
-
A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
-
B. Hsiang Y. Zhu Z. Wang Y. Wu V. Sasseville W.P. Yang T.G. Kirchgessner A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters J. Biol. Chem. 274 1999 37161 37168
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37161-37168
-
-
Hsiang, B.1
Zhu, Y.2
Wang, Z.3
Wu, Y.4
Sasseville, V.5
Yang, W.P.6
Kirchgessner, T.G.7
-
46
-
-
0023185436
-
Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion
-
M. Huber A. Guhlmann P.L. Jansen D. Keppler Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion Hepatology 7 1987 224 228
-
(1987)
Hepatology
, vol.7
, pp. 224-228
-
-
Huber, M.1
Guhlmann, A.2
Jansen, P.L.3
Keppler, D.4
-
47
-
-
0025202864
-
Metabolism of cysteinyl leukotrienes in monkey and man
-
M. Huber J. Müller I. Leier G. Jedlitschky H.A. Ball K.P. Moore G.W. Taylor R. Williams D. Keppler Metabolism of cysteinyl leukotrienes in monkey and man Eur. J. Biochem. 194 1990 309 315
-
(1990)
Eur. J. Biochem.
, vol.194
, pp. 309-315
-
-
Huber, M.1
Müller, J.2
Leier, I.3
Jedlitschky, G.4
Ball, H.A.5
Moore, K.P.6
Taylor, G.W.7
Williams, R.8
Keppler, D.9
-
48
-
-
0024472768
-
ATP/Mg2+-dependent cardiac transport system for glutathione S-conjugates. A study using rat heart sarcolemma vesicles
-
T. Ishikawa ATP/Mg2+-dependent cardiac transport system for glutathione S-conjugates. A study using rat heart sarcolemma vesicles J. Biol. Chem. 264 1989 17343 17348
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 17343-17348
-
-
Ishikawa, T.1
-
49
-
-
0025132673
-
ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates
-
T. Ishikawa M. Müller C. Klünemann T. Schaub D. Keppler ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates J. Biol. Chem. 265 1990 19279 19286
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 19279-19286
-
-
Ishikawa, T.1
Müller, M.2
Klünemann, C.3
Schaub, T.4
Keppler, D.5
-
51
-
-
0031916830
-
Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver
-
K. Ito H. Suzuki T. Hirohashi K. Kume T. Shimizu Y. Sugiyama Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver J. Biol. Chem. 273 1998 1684 1688
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1684-1688
-
-
Ito, K.1
Suzuki, H.2
Hirohashi, T.3
Kume, K.4
Shimizu, T.5
Sugiyama, Y.6
-
52
-
-
0028001416
-
ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein
-
G. Jedlitschky I. Leier U. Buchholz M. Center D. Keppler ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein Cancer Res. 54 1994 4833 4836
-
(1994)
Cancer Res.
, vol.54
, pp. 4833-4836
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Center, M.4
Keppler, D.5
-
53
-
-
0027935783
-
Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent ATP-dependent transport across the canalicular membrane
-
G. Jedlitschky I. Leier M. Böhme U. Buchholz J. Bar-Tans D. Keppler Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent ATP-dependent transport across the canalicular membrane Biochem. Pharmacol. 48 1994 1113 1120
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1113-1120
-
-
Jedlitschky, G.1
Leier, I.2
Böhme, M.3
Buchholz, U.4
Bar-Tans, J.5
Keppler, D.6
-
54
-
-
0030063480
-
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
-
G. Jedlitschky I. Leier U. Buchholz K. Barnouin G. Kurz D. Keppler Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump Cancer Res. 56 1996 988 994
-
(1996)
Cancer Res.
, vol.56
, pp. 988-994
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Barnouin, K.4
Kurz, G.5
Keppler, D.6
-
55
-
-
0030668526
-
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2
-
G. Jedlitschky I. Leier U. Buchholz J. Hummel-Eisenbeiss B. Burchell D. Keppler ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2 Biochem. J. 327 1997 305 310
-
(1997)
Biochem. J.
, vol.327
, pp. 305-310
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Hummel-Eisenbeiss, J.4
Burchell, B.5
Keppler, D.6
-
56
-
-
0034730755
-
The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
-
G. Jedlitschky B. Burchell D. Keppler The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides J. Biol. Chem. 275 2000 30069 30074
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30069-30074
-
-
Jedlitschky, G.1
Burchell, B.2
Keppler, D.3
-
57
-
-
0024498508
-
Pharmacology of the leukotriene antagonist verlukast: The (R)-enantiomer of MK-571
-
T.R. Jones R. Zamboni M. Belley E. Champion L. Charette A.W. Ford-Hutchinson J.Y. Gauthier S. Leger A. Lord P. Masson S. McFarlane H. Piechuta J. Rokach H. Williams R.N. Young R.N. DeHaven S.S. Pong Pharmacology of the leukotriene antagonist verlukast: The (R)-enantiomer of MK-571 Can. J. Physiol. Pharmacol. 67 1989 17 28
-
(1989)
Can. J. Physiol. Pharmacol.
, vol.67
, pp. 17-28
-
-
Jones, T.R.1
Zamboni, R.2
Belley, M.3
Champion, E.4
Charette, L.5
Ford-Hutchinson, A.W.6
Gauthier, J.Y.7
Leger, S.8
Lord, A.9
Masson, P.10
McFarlane, S.11
Piechuta, H.12
Rokach, J.13
Williams, H.14
Young, R.N.15
DeHaven, R.N.16
Pong, S.S.17
-
58
-
-
0032769284
-
Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2
-
T. Kamisako I. Leier Y. Cui J. König U. Buchholz J. Hummel-Eisenbeiss D. Keppler Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2 Hepatology 30 1999 485 490
-
(1999)
Hepatology
, vol.30
, pp. 485-490
-
-
Kamisako, T.1
Leier, I.2
Cui, Y.3
König, J.4
Buchholz, U.5
Hummel-Eisenbeiss, J.6
Keppler, D.7
-
60
-
-
0027014477
-
Leukotrienes: Biosynthesis, transport, inactivation, and analysis
-
D. Keppler Leukotrienes: Biosynthesis, transport, inactivation, and analysis Rev. Physiol. Biochem. Pharmacol. 121 1992 1 30
-
(1992)
Rev. Physiol. Biochem. Pharmacol.
, vol.121
, pp. 1-30
-
-
Keppler, D.1
-
61
-
-
0031160517
-
Hepatic canalicular membrane 5: Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver
-
D. Keppler J. König Hepatic canalicular membrane 5: Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver FASEB J. 11 1997 509 516
-
(1997)
FASEB J.
, vol.11
, pp. 509-516
-
-
Keppler, D.1
König, J.2
-
62
-
-
0032323643
-
Transport function and substrate specificity of multidrug resistance protein
-
D. Keppler G. Jedlitschky I. Leier Transport function and substrate specificity of multidrug resistance protein Meth. Enzymol. 292 1998 607 616
-
(1998)
Meth. Enzymol.
, vol.292
, pp. 607-616
-
-
Keppler, D.1
Jedlitschky, G.2
Leier, I.3
-
64
-
-
0034099587
-
Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family
-
D. Keppler T. Kamisako I. Leier Y. Cui A.T. Nies H. Tsujii J. König Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family Advan. Enzyme Regul. 40 2000 339 349
-
(2000)
Advan. Enzyme Regul.
, vol.40
, pp. 339-349
-
-
Keppler, D.1
Kamisako, T.2
Leier, I.3
Cui, Y.4
Nies, A.T.5
Tsujii, H.6
König, J.7
-
65
-
-
0002343251
-
Conjugate export pumps of the multidrug resistance protein (MRP) family in liver
-
D. Keppler J. König A.T. Nies Conjugate export pumps of the multidrug resistance protein (MRP) family in liver I.M. Arias The Liver: Biology and Pathobiology 2001 Lippincott Williams & Wilkins Philadelphia 373 382
-
(2001)
, pp. 373-382
-
-
Keppler, D.1
König, J.2
Nies, A.T.3
-
67
-
-
0024235239
-
ATP stimulates the uptake of S-dinitrophenylglutathione by rat liver plasma membrane vesicles
-
K. Kobayashi Y. Sogame K. Hayashi P. Nicotera S. Orrenius ATP stimulates the uptake of S -dinitrophenylglutathione by rat liver plasma membrane vesicles FEBS Lett. 240 1988 55 58
-
(1988)
FEBS Lett.
, vol.240
, pp. 55-58
-
-
Kobayashi, K.1
Sogame, Y.2
Hayashi, K.3
Nicotera, P.4
Orrenius, S.5
-
68
-
-
0039476506
-
Glutathione transport by inside-out vesicles from human erythrocytes
-
T. Kondo G.L. Dale E. Beutler Glutathione transport by inside-out vesicles from human erythrocytes Proc. Natl. Acad. Sci. USA 77 1980 6359 6362
-
(1980)
, pp. 6359-6362
-
-
Kondo, T.1
Dale, G.L.2
Beutler, E.3
-
69
-
-
0020164655
-
Glutathione S-conjugate transport using inside-out vesicles from human erythrocytes
-
T. Kondo M. Murao N. Taniguchi Glutathione S -conjugate transport using inside-out vesicles from human erythrocytes Eur. J. Biochem. 125 1982 551 554
-
(1982)
Eur. J. Biochem.
, vol.125
, pp. 551-554
-
-
Kondo, T.1
Murao, M.2
Taniguchi, N.3
-
70
-
-
0032926354
-
Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
-
J. König D. Rost Y. Cui D. Keppler Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane Hepatology 29 1999 1156 1163
-
(1999)
Hepatology
, vol.29
, pp. 1156-1163
-
-
König, J.1
Rost, D.2
Cui, Y.3
Keppler, D.4
-
71
-
-
0344927562
-
Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
-
J. König A.T. Nies Y. Cui I. Leier D. Keppler Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance Biochim. Biophys. Acta 1461 1999 377 394
-
(1999)
Biochim. Biophys. Acta
, vol.1461
, pp. 377-394
-
-
König, J.1
Nies, A.T.2
Cui, Y.3
Leier, I.4
Keppler, D.5
-
72
-
-
0037733365
-
A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane
-
J. König Y. Cui A.T. Nies D. Keppler A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane Am. J. Physiol. 278 2000 G156 G164
-
(2000)
Am. J. Physiol.
, vol.278
, pp. G156-G164
-
-
König, J.1
Cui, Y.2
Nies, A.T.3
Keppler, D.4
-
73
-
-
0034725617
-
Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide
-
J. König Y. Cui A.T. Nies D. Keppler Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide J. Biol. Chem. 275 2000 23161 23168
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23161-23168
-
-
König, J.1
Cui, Y.2
Nies, A.T.3
Keppler, D.4
-
74
-
-
0030841332
-
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
-
M. Kool M. de Haas G.L. Scheffer R.J. Scheper M.J. van Eijk J.A. Juijn F. Baas P. Borst Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines Cancer Res. 57 1997 3537 3547
-
(1997)
Cancer Res.
, vol.57
, pp. 3537-3547
-
-
Kool, M.1
de Haas, M.2
Scheffer, G.L.3
Scheper, R.J.4
van Eijk, M.J.5
Juijn, J.A.6
Baas, F.7
Borst, P.8
-
75
-
-
0027249710
-
The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein
-
N. Krishnamachary M.S. Center The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein Cancer Res. 53 1993 3658 3661
-
(1993)
Cancer Res.
, vol.53
, pp. 3658-3661
-
-
Krishnamachary, N.1
Center, M.S.2
-
77
-
-
85112884305
-
Leukotriene C4 uses a probenecid-sensitive export carrier that does not recognize leukotriene B4
-
4 Proc. Natl. Acad. Sci. USA 89 1992 11598 11602
-
(1992)
, pp. 11598-11602
-
-
Lam, B.K.1
Xu, K.2
Atkins, M.B.3
Austen, K.F.4
-
78
-
-
0029821995
-
Multidrug resistance mediated by the multidrug resistance protein (MRP) gene
-
D. Lautier Y. Canitrot R.G. Deeley S.P. Cole Multidrug resistance mediated by the multidrug resistance protein (MRP) gene Biochem. Pharmacol. 52 1996 967 977
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 967-977
-
-
Lautier, D.1
Canitrot, Y.2
Deeley, R.G.3
Cole, S.P.4
-
80
-
-
0028347079
-
Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells
-
I. Leier G. Jedlitschky U. Buchholz D. Keppler Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells Eur. J. Biochem. 220 1994 599 606
-
(1994)
Eur. J. Biochem.
, vol.220
, pp. 599-606
-
-
Leier, I.1
Jedlitschky, G.2
Buchholz, U.3
Keppler, D.4
-
81
-
-
0027984511
-
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates
-
I. Leier G. Jedlitschky U. Buchholz S.P. Cole R.G. Deeley D. Keppler The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates J. Biol. Chem. 269 1994 27807 27810
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27807-27810
-
-
Leier, I.1
Jedlitschky, G.2
Buchholz, U.3
Cole, S.P.4
Deeley, R.G.5
Keppler, D.6
-
82
-
-
0029806319
-
Identification of the biosynthetic leukotriene C4 export pump in murine mastocytoma cells as a homolog of the multidrug resistance protein
-
I. Leier G. Jedlitschky M. Büchler U. Buchholz M. Brom D. Keppler Identification of the biosynthetic leukotriene C4 export pump in murine mastocytoma cells as a homolog of the multidrug resistance protein Eur. J. Biochem. 242 1996 201 205
-
(1996)
Eur. J. Biochem.
, vol.242
, pp. 201-205
-
-
Leier, I.1
Jedlitschky, G.2
Büchler, M.3
Buchholz, U.4
Brom, M.5
Keppler, D.6
-
84
-
-
0034083906
-
ATP-dependent paraaminohippurate transport by apical multidrug resistance protein MRP2
-
I. Leier J. Hummel-Eisenbeiss Y. Cui D. Keppler ATP-dependent paraaminohippurate transport by apical multidrug resistance protein MRP2 Kidney Int. 57 2000 1636 1642
-
(2000)
Kidney Int.
, vol.57
, pp. 1636-1642
-
-
Leier, I.1
Hummel-Eisenbeiss, J.2
Cui, Y.3
Keppler, D.4
-
85
-
-
0035033774
-
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids
-
E.M. Leslie Q. Mao C.J. Oleschuk R.G. Deeley S.P. Cole Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids Mol. Pharmacol. 59 2001 1171 1180
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1171-1180
-
-
Leslie, E.M.1
Mao, Q.2
Oleschuk, C.J.3
Deeley, R.G.4
Cole, S.P.5
-
86
-
-
0035958862
-
Transport of the beta-O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-butanol (NNAL) by the multidrug resistance protein 1 (MRP1/ABCC1): Requirement for glutathione or a non-sulfur-containing analog
-
E.M. Leslie K.-I. Ito P. Upadhyaya S.S. Hecht R.G. Deeley S.P. Cole Transport of the beta-O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-butanol (NNAL) by the multidrug resistance protein 1 (MRP1/ABCC1): Requirement for glutathione or a non-sulfur-containing analog J. Biol. Chem. 276 2001 27846 27854
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27846-27854
-
-
Leslie, E.M.1
Ito, K.-I.2
Upadhyaya, P.3
Hecht, S.S.4
Deeley, R.G.5
Cole, S.P.6
-
87
-
-
0032568838
-
Identification of glutathione as a driving force and leukotriene C4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter
-
4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter J. Biol. Chem. 273 1998 16184 16191
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16184-16191
-
-
Li, L.1
Lee, T.K.2
Meier, P.J.3
Ballatori, N.4
-
88
-
-
0030009305
-
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport
-
D.W. Loe K.C. Almquist R.G. Deeley S.P. Cole Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport J. Biol. Chem. 271 1996 9675 9682
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9675-9682
-
-
Loe, D.W.1
Almquist, K.C.2
Deeley, R.G.3
Cole, S.P.4
-
89
-
-
0029918142
-
ATP-dependent 17 betaestradiol 17-(beta-d-glucuronide) transport by multidrug resistance protein (MRP) Inhibition by cholestatic steroids
-
D.W. Loe K.C. Almquist S.P. Cole R.G. Deeley ATP-dependent 17 betaestradiol 17-(beta- d -glucuronide) transport by multidrug resistance protein (MRP) Inhibition by cholestatic steroids J. Biol. Chem. 271 1996 9683 9689
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9683-9689
-
-
Loe, D.W.1
Almquist, K.C.2
Cole, S.P.3
Deeley, R.G.4
-
90
-
-
0030962253
-
ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene
-
D.W. Loe R.K. Stewart T.E. Massey R.G. Deeley S.P. Cole ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene Mol. Pharmacol. 51 1997 1034 1041
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 1034-1041
-
-
Loe, D.W.1
Stewart, R.K.2
Massey, T.E.3
Deeley, R.G.4
Cole, S.P.5
-
91
-
-
0032534064
-
Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
-
D.W. Loe R.G. Deeley S.P. Cole Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione Cancer Res. 58 1998 5130 5136
-
(1998)
Cancer Res.
, vol.58
, pp. 5130-5136
-
-
Loe, D.W.1
Deeley, R.G.2
Cole, S.P.3
-
92
-
-
0034012019
-
Verapamil stimulates glutathione transport by the 190-kDa multidrug resistance protein 1(MRP1)
-
D.W. Loe R.G. Deeley S.P. Cole Verapamil stimulates glutathione transport by the 190-kDa multidrug resistance protein 1(MRP1) J. Pharmacol. Exp. Ther. 293 2000 530 538
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 530-538
-
-
Loe, D.W.1
Deeley, R.G.2
Cole, S.P.3
-
93
-
-
0030665969
-
Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
-
A. Lorico G. Rappa R.A. Finch D. Yang R.A. Flavell A.C. Sartorelli Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione Cancer Res. 57 1997 5238 5242
-
(1997)
Cancer Res.
, vol.57
, pp. 5238-5242
-
-
Lorico, A.1
Rappa, G.2
Finch, R.A.3
Yang, D.4
Flavell, R.A.5
Sartorelli, A.C.6
-
95
-
-
0034602270
-
Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles
-
Q. Mao R.G. Deeley S.P. Cole Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles J. Biol. Chem. 275 2000 34166 34172
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34166-34172
-
-
Mao, Q.1
Deeley, R.G.2
Cole, S.P.3
-
96
-
-
0025267059
-
Mechanisms of multidrug resistance in HL60 cells: Detection of resistance-associated proteins with antibodies against synthetic peptides that correspond to the deduced sequence of P-glycoprotein
-
D. Marquardt S. McCrone M.S. Center Mechanisms of multidrug resistance in HL60 cells: Detection of resistance-associated proteins with antibodies against synthetic peptides that correspond to the deduced sequence of P-glycoprotein Cancer Res. 50 1990 1426 1430
-
(1990)
Cancer Res.
, vol.50
, pp. 1426-1430
-
-
Marquardt, D.1
McCrone, S.2
Center, M.S.3
-
97
-
-
0029133131
-
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes
-
R. Mayer J. Kartenbeck M. Büchler G. Jedlitschky I. Leier D. Keppler Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes J. Cell Biol. 131 1995 137 150
-
(1995)
J. Cell Biol.
, vol.131
, pp. 137-150
-
-
Mayer, R.1
Kartenbeck, J.2
Büchler, M.3
Jedlitschky, G.4
Leier, I.5
Keppler, D.6
-
98
-
-
0023278073
-
Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein
-
T. McGrath M.S. Center Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein Biochem. Biophys. Res. Commun. 145 1987 1171 1176
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.145
, pp. 1171-1176
-
-
McGrath, T.1
Center, M.S.2
-
99
-
-
0023278796
-
Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin
-
S.E. Mirski J.H. Gerlach S.P. Cole Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin Cancer Res. 47 1987 2594 2598
-
(1987)
Cancer Res.
, vol.47
, pp. 2594-2598
-
-
Mirski, S.E.1
Gerlach, J.H.2
Cole, S.P.3
-
100
-
-
0028578004
-
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport
-
M. Müller C. Meijer G.J. Zaman P. Borst R.J. Scheper N.H. Mulder E.G. de Vries P.L. Jansen Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport Proc. Natl. Acad. Sci. USA 91 1994 13033 13037
-
(1994)
, pp. 13033-13037
-
-
Müller, M.1
Meijer, C.2
Zaman, G.J.3
Borst, P.4
Scheper, R.J.5
Mulder, N.H.6
de Vries, E.G.7
Jansen, P.L.8
-
101
-
-
0001465756
-
Leukotriene C: A slow-reacting substance from murine mastocytoma cells
-
R.C. Murphy S. Hammarström B. Samuelsson Leukotriene C: A slow-reacting substance from murine mastocytoma cells Proc. Natl. Acad. Sci. USA 76 1979 4275 4279
-
(1979)
, pp. 4275-4279
-
-
Murphy, R.C.1
Hammarström, S.2
Samuelsson, B.3
-
102
-
-
0031758818
-
Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B
-
A.T. Nies T. Cantz M. Brom I. Leier D. Keppler Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B Hepatology 28 1998 1332 1340
-
(1998)
Hepatology
, vol.28
, pp. 1332-1340
-
-
Nies, A.T.1
Cantz, T.2
Brom, M.3
Leier, I.4
Keppler, D.5
-
103
-
-
0030818770
-
Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: Comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide
-
K. Niinuma O. Takenaka T. Horie K. Kobayashi Y. Kato H. Suzuki Y. Sugiyama Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: Comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide J. Pharmacol. Exp. Ther. 282 1997 866 872
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.282
, pp. 866-872
-
-
Niinuma, K.1
Takenaka, O.2
Horie, T.3
Kobayashi, K.4
Kato, Y.5
Suzuki, H.6
Sugiyama, Y.7
-
104
-
-
0026490803
-
Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia
-
T. Nishida Z. Gatmaitan J. Roy-Chowdhry I.M. Arias Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia J. Clin. Invest. 90 1992 2130 2135
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 2130-2135
-
-
Nishida, T.1
Gatmaitan, Z.2
Roy-Chowdhry, J.3
Arias, I.M.4
-
105
-
-
0032449122
-
Inhibitors of MRP1-mediated multidrug resistance
-
B.H. Norman Inhibitors of MRP1-mediated multidrug resistance Drugs Future 23 1998 1001 1013
-
(1998)
Drugs Future
, vol.23
, pp. 1001-1013
-
-
Norman, B.H.1
-
106
-
-
85112885033
-
Structure activity relationships of tricyclic isoxazoles. A novel class of selective MRP1 modulators
-
B.H. Norman J.M. Gruber J.S. Kroin P.A. Lander M.C. Lohman S.P. Hollinshead J.W. Wilson J.J. Starling K.L. Law T.D. Self L.B. Tabas D.C. Williams D.C. Paul M.M. Wagner A.H. Dantzig Structure activity relationships of tricyclic isoxazoles. A novel class of selective MRP1 modulators Proc. Am. Assoc. Cancer Res. 42 2001 5103
-
(2001)
, pp. 5103
-
-
Norman, B.H.1
Gruber, J.M.2
Kroin, J.S.3
Lander, P.A.4
Lohman, M.C.5
Hollinshead, S.P.6
Wilson, J.W.7
Starling, J.J.8
Law, K.L.9
Self, T.D.10
Tabas, L.B.11
Williams, D.C.12
Paul, D.C.13
Wagner, M.M.14
Dantzig, A.H.15
-
107
-
-
85112952150
-
Selective modulation of MRP1 function by the tricyclic isoxazole, LY 402913 and analogs of the natural product rufomycin
-
D.C. Paul X. Xia M.M. Wagner K.L. Law J.M. Gruber B.H. Norman P. Kulanthaivel J.J. Starling D.C. Williams Selective modulation of MRP1 function by the tricyclic isoxazole, LY 402913 and analogs of the natural product rufomycin Proc. Am. Assoc. Cancer Res. 42 2001 5119
-
(2001)
, pp. 5119
-
-
Paul, D.C.1
Xia, X.2
Wagner, M.M.3
Law, K.L.4
Gruber, J.M.5
Norman, B.H.6
Kulanthaivel, P.7
Starling, J.J.8
Williams, D.C.9
-
108
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
C.C. Paulusma P.J. Bosma G.J. Zaman C.T. Bakker M. Otter G.L. Scheffer R.J. Scheper P. Borst R.P. Oude Elferink Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene Science 271 1996 1126 1128
-
(1996)
Science
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.3
Bakker, C.T.4
Otter, M.5
Scheffer, G.L.6
Scheper, R.J.7
Borst, P.8
Oude Elferink, R.P.9
-
109
-
-
0030994468
-
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome
-
C.C. Paulusma M. Kool P.J. Bosma G.L. Scheffer F. ter Borg R.J. Scheper G.N. Tytgat P. Borst F. Baas R.P. Oude Elferink A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome Hepatology 25 1997 1539 1542
-
(1997)
Hepatology
, vol.25
, pp. 1539-1542
-
-
Paulusma, C.C.1
Kool, M.2
Bosma, P.J.3
Scheffer, G.L.4
ter Borg, F.5
Scheper, R.J.6
Tytgat, G.N.7
Borst, P.8
Baas, F.9
Oude Elferink, R.P.10
-
110
-
-
0033104810
-
Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione
-
C.C. Paulusma M.A. van Geer R. Evers M. Heijn R. Ottenhoff P. Borst R.P. Oude Elferink Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione Biochem. J. 338 1999 393 401
-
(1999)
Biochem. J.
, vol.338
, pp. 393-401
-
-
Paulusma, C.C.1
van Geer, M.A.2
Evers, R.3
Heijn, M.4
Ottenhoff, R.5
Borst, P.6
Oude Elferink, R.P.7
-
111
-
-
0029958285
-
Identification of the multidrug resistance protein (MRP) as the glutathione-S-conjugate export pump of erythrocytes
-
L. Pulaski G. Jedlitschky I. Leier U. Buchholz D. Keppler Identification of the multidrug resistance protein (MRP) as the glutathione-S-conjugate export pump of erythrocytes Eur. J. Biochem. 241 1996 644 648
-
(1996)
Eur. J. Biochem.
, vol.241
, pp. 644-648
-
-
Pulaski, L.1
Jedlitschky, G.2
Leier, I.3
Buchholz, U.4
Keppler, D.5
-
112
-
-
0035794228
-
Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1
-
Y.M. Qian W.C. Song H. Cui S.P. Cole R.G. Deeley Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1 J. Biol. Chem. 276 2001 6404 6411
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6404-6411
-
-
Qian, Y.M.1
Song, W.C.2
Cui, H.3
Cole, S.P.4
Deeley, R.G.5
-
113
-
-
0033567429
-
New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models
-
G. Rappa R.A. Finch A.C. Sartorelli A. Lorico New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models Biochem. Pharmacol. 58 1909 557 562
-
(1909)
Biochem. Pharmacol.
, vol.58
, pp. 557-562
-
-
Rappa, G.1
Finch, R.A.2
Sartorelli, A.C.3
Lorico, A.4
-
115
-
-
0033021424
-
ATP-and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1
-
J. Renes E.G. de Vries E.F. Nienhuis P.L. Jansen M. Müller ATP-and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1 Br. J. Pharmacol. 126 1999 681 688
-
(1999)
Br. J. Pharmacol.
, vol.126
, pp. 681-688
-
-
Renes, J.1
de Vries, E.G.2
Nienhuis, E.F.3
Jansen, P.L.4
Müller, M.5
-
117
-
-
0032446450
-
Enhancement of glucuronosyl etoposide transport by glutathione in multidrug resistance-associated protein-overexpressing cells
-
H. Sakamoto H. Hara K. Hirano T. Adachi Enhancement of glucuronosyl etoposide transport by glutathione in multidrug resistance-associated protein-overexpressing cells Cancer Lett. 135 1999 113 119
-
(1999)
Cancer Lett.
, vol.135
, pp. 113-119
-
-
Sakamoto, H.1
Hara, H.2
Hirano, K.3
Adachi, T.4
-
119
-
-
0023177955
-
Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects
-
B. Samuelsson S.E. Dahlen J.A. Lindgren C.A. Rouzer C.N. Serhan Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects Science 237 1987 1171 1176
-
(1987)
Science
, vol.237
, pp. 1171-1176
-
-
Samuelsson, B.1
Dahlen, S.E.2
Lindgren, J.A.3
Rouzer, C.A.4
Serhan, C.N.5
-
121
-
-
0031911625
-
Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats
-
H. Sasabe A. Tsuji Y. Sugiyama Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats J. Pharmacol. Exp. Ther. 284 1998 1033 1039
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 1033-1039
-
-
Sasabe, H.1
Tsuji, A.2
Sugiyama, Y.3
-
123
-
-
0026018768
-
ATP-dependent leukotriene export from mastocytoma cells
-
T. Schaub T. Ishikawa D. Keppler ATP-dependent leukotriene export from mastocytoma cells FEBS Lett. 279 1991 83 86
-
(1991)
FEBS Lett.
, vol.279
, pp. 83-86
-
-
Schaub, T.1
Ishikawa, T.2
Keppler, D.3
-
125
-
-
0033032730
-
Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma
-
T.P. Schaub J. Kartenbeck J. König H. Spring J. Dörsam G. Staehler S. Störkel W.F. Thon D. Keppler Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma J. Am. Soc. Nephrol. 10 1999 1159 1169
-
(1999)
J. Am. Soc. Nephrol.
, vol.10
, pp. 1159-1169
-
-
Schaub, T.P.1
Kartenbeck, J.2
König, J.3
Spring, H.4
Dörsam, J.5
Staehler, G.6
Störkel, S.7
Thon, W.F.8
Keppler, D.9
-
126
-
-
0035869301
-
Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia
-
M.J. Schultz J. Wijnholds M.P. Peppelenbosch M.J. Vervoordeldonk P. Speelman S.J. van Deventer P. Borst T. van der Poll Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae -induced pneumonia J. Immunol. 166 2001 4059 4064
-
(2001)
J. Immunol.
, vol.166
, pp. 4059-4064
-
-
Schultz, M.J.1
Wijnholds, J.2
Peppelenbosch, M.P.3
Vervoordeldonk, M.J.4
Speelman, P.5
van Deventer, S.J.6
Borst, P.7
van der Poll, T.8
-
127
-
-
0029939542
-
Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter
-
B.D. Stride G. Valdimarsson J.H. Gerlach G.M. Wilson S.P. Cole R.G. Deeley Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter Mol. Pharmacol. 49 1996 962 971
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 962-971
-
-
Stride, B.D.1
Valdimarsson, G.2
Gerlach, J.H.3
Wilson, G.M.4
Cole, S.P.5
Deeley, R.G.6
-
128
-
-
0030775395
-
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells
-
B.D. Stride C.E. Grant D.W. Loe D.R. Hipfner S.P.C. Cole R.G. Deeley Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells Mol. Pharmacol. 52 1997 344 353
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 344-353
-
-
Stride, B.D.1
Grant, C.E.2
Loe, D.W.3
Hipfner, D.R.4
Cole, S.P.C.5
Deeley, R.G.6
-
129
-
-
0030969806
-
Reversal of multidrug resistance-associated protein-mediated drug resistance by the pyridine analog PAK-104P
-
T. Sumizawa Z.S. Chen Y. Chuman K. Seto T. Furukawa M. Haraguchi A. Tani N. Shudo S.I. Akiyama Reversal of multidrug resistance-associated protein-mediated drug resistance by the pyridine analog PAK-104P Mol. Pharmacol. 51 1997 399 405
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 399-405
-
-
Sumizawa, T.1
Chen, Z.S.2
Chuman, Y.3
Seto, K.4
Furukawa, T.5
Haraguchi, M.6
Tani, A.7
Shudo, N.8
Akiyama, S.I.9
-
131
-
-
9544233652
-
A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
-
K. Taniguchi M. Wada K. Kohno T. Nakamura T. Kawabe M. Kawakami K. Kagotani K. Okumura S. Akiyama M. Kuwano A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation Cancer Res. 56 1996 4124 4129
-
(1996)
Cancer Res.
, vol.56
, pp. 4124-4129
-
-
Taniguchi, K.1
Wada, M.2
Kohno, K.3
Nakamura, T.4
Kawabe, T.5
Kawakami, M.6
Kagotani, K.7
Okumura, K.8
Akiyama, S.9
Kuwano, M.10
-
132
-
-
0020546649
-
Characteristics of the uptake of cysteine-containing leukotrienes by isolated hepatocytes
-
N. Uehara K. Ormstad L. Orning S. Hammarstrom Characteristics of the uptake of cysteine-containing leukotrienes by isolated hepatocytes Biochim. Biophys. Acta 732 1983 69 74
-
(1983)
Biochim. Biophys. Acta
, vol.732
, pp. 69-74
-
-
Uehara, N.1
Ormstad, K.2
Orning, L.3
Hammarstrom, S.4
-
134
-
-
0029867130
-
PAK-104P, a pyridine analogue, reverses paclitaxel and doxorubicin resistance in cell lines and nude mice bearing xenografts that overexpress the multidrug resistance protein
-
U. Vanhoefer S. Cao H. Minderman K. Toth R.J. Scheper M.L. Slovak Y.M. Rustum PAK-104P, a pyridine analogue, reverses paclitaxel and doxorubicin resistance in cell lines and nude mice bearing xenografts that overexpress the multidrug resistance protein Clin. Cancer Res. 2 1996 369 377
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 369-377
-
-
Vanhoefer, U.1
Cao, S.2
Minderman, H.3
Toth, K.4
Scheper, R.J.5
Slovak, M.L.6
Rustum, Y.M.7
-
136
-
-
20244386956
-
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
-
J. Wijnholds R. Evers M.R. van Leusden C.A. Mol G.J. Zaman U. Mayer J.H. Beijnen M. van der Valk P. Krimpenfort P. Borst Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein Nat. Med. 3 1997 1275 1279
-
(1997)
Nat. Med.
, vol.3
, pp. 1275-1279
-
-
Wijnholds, J.1
Evers, R.2
van Leusden, M.R.3
Mol, C.A.4
Zaman, G.J.5
Mayer, U.6
Beijnen, J.H.7
van der Valk, M.8
Krimpenfort, P.9
Borst, P.10
-
138
-
-
0030862073
-
Biliary excretion of pravastatin in rats: Contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter
-
M. Yamazaki S. Akiyama K. Ni'inuma R. Nishigaki Y. Sugiyama Biliary excretion of pravastatin in rats: Contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter Drug Metab. Dispos. 25 1997 1123 1129
-
(1997)
Drug Metab. Dispos.
, vol.25
, pp. 1123-1129
-
-
Yamazaki, M.1
Akiyama, S.2
Ni'inuma, K.3
Nishigaki, R.4
Sugiyama, Y.5
-
139
-
-
0028567035
-
The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump
-
G.J. Zaman M.J. Flens M.R. van Leusden M. de Haas H.S. Mülder J. Lankelma H.M. Pinedo R.J. Scheper F. Baas H.J. Broxterman P. Borst The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump Proc. Natl. Acad. Sci. USA 91 1994 8822 8826
-
(1994)
, pp. 8822-8826
-
-
Zaman, G.J.1
Flens, M.J.2
van Leusden, M.R.3
de Haas, M.4
Mülder, H.S.5
Lankelma, J.6
Pinedo, H.M.7
Scheper, R.J.8
Baas, F.9
Broxterman, H.J.10
Borst, P.11
-
140
-
-
0029095763
-
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein
-
G.J. Zaman J. Lankelma O. van Tellingen J. Beijnen H. Dekker C. Paulusma R.P. Oude Elferink F. Baas P. Borst Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein Proc. Natl. Acad. Sci. USA 92 1995 7690 7694
-
(1995)
, pp. 7690-7694
-
-
Zaman, G.J.1
Lankelma, J.2
van Tellingen, O.3
Beijnen, J.4
Dekker, H.5
Paulusma, C.6
Oude Elferink, R.P.7
Baas, F.8
Borst, P.9
-
141
-
-
0030570805
-
Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP
-
G.J. Zaman N.H. Cnubben P.J. van Bladeren R. Evers P. Borst Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP FEBS Lett. 391 1996 126 130
-
(1996)
FEBS Lett.
, vol.391
, pp. 126-130
-
-
Zaman, G.J.1
Cnubben, N.H.2
van Bladeren, P.J.3
Evers, R.4
Borst, P.5
-
142
-
-
0023140620
-
Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line
-
J.G. Zijlstra E.G. de Vries N.H. Mulder Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line Cancer Res. 47 1987 1780 1784
-
(1987)
Cancer Res.
, vol.47
, pp. 1780-1784
-
-
Zijlstra, J.G.1
de Vries, E.G.2
Mulder, N.H.3
|