Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

Journal of Biological Chemistry

Volumn 278, Issue 14, 2003, Pages 12361-12366

  Plas, David R ^b   Thompson, Craig B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; PROTEINS; SUBSTRATES;

CELL GROWTH;

GROWTH KINETICS;

GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; PROTEIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TUBERIN; UBIQUITIN; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; DNA BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; INTERLEUKIN 3; INTERLEUKIN 3 RECEPTOR; MULTIENZYME COMPLEX; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; UBIQUITINATION; ANIMAL; CELL LINE; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-3; MICE; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, INTERLEUKIN-3; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN;

EID: 0038362751     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M213069200     Document Type: Article

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