Insulin dose-response effects on memory and plasma amyloid precursor protein in Alzheimer's disease: Interactions with apolipoprotein E genotype

Psychoneuroendocrinology

Volumn 28, Issue 6, 2003, Pages 809-822

  Craft, Suzanne ^a,b   Asthana, Sanjay ^a,b   Cook, David G ^a,b   Baker, Laura D ^a,b   Cherrier, Monique ^b   Purganan, Kristina ^a   Wait, Colby ^a   Petrova, Andreana ^a   Latendresse, Shawn ^a   Watson, G Stennis ^a,b   Newcomer, John W ^c   Schellenberg, Gerard D ^a,b   Krohn, Aaron J ^a  

^a Education   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

Amyloid beta protein precursor; Apolipoproteins e; Diabetes; Energy metabolism; Insulin resistance; MESH terms

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; INSULIN;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; GENOTYPE; GLUCOSE BLOOD LEVEL; HOMOZYGOTE; HUMAN; INSULIN BLOOD LEVEL; MALE; MEMORY DISORDER; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TREATMENT OUTCOME;

EID: 0038177803     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4530(02)00087-2     Document Type: Article

References (36)

1. Aplin A., Gibb G., Jacobsen J., Gallo J., Anderton B. In Vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein synthase kinase-3beta. Journal of Neurochemistry. 67:(2(August)):1996;699-707.
2. Aplin A., Jacobsen J., Anderton B., Gallo J. Effect of increased glycogen synthase kinase-3 activity upon the maturation of the amyloid precursor protein in transfected cells. Molecular Neuroscience. 8:(3(February)):1997;639-643.
3. Boyt A.A., Taddei K., Hallmeyer J., Helmerhorst E., Gandy S.E., Craft S., Martins R.N. The effect of insulin and glucose on the plasma concentration of Alzheimer's amyloid precursor protein. Neuroscience. 95:(3):2000;727-734.
4. Bush A.I., Martins R.N., Rumble B., Moir R., Fuller S., Milward E., Currie J., Ames D., Weidemann A., Fischer P., et al. The amyloid precursor protein of Alzheimer's disease is released by human platelets. Journal of Biological Chemistry. 265:(15):1990;15977-15983.
5. Bush A.I., Whyte S., Thomas L.D., Williamson T.G., Van Tiggelen C.J., Currie J., Small D.H., Moir R.D., Li Q.X., Rumble B., et al. An abnormality of plasma amyloid protein precursor in Alzheimer's disease. Annals of Neurology. 32:(1):1992;57-65.
6. Craft S., Asthana S., Newcomer J.W., Wilkinson C.W., Matos I.T., Baker L.D., Cherrier M., Lofgreen C., Latendresse S., Petrova A., Plymate S., Raskind M., Grimwood K., Veith R.C. Enhancement of memory in Alzheimer's disease with insulin and somatostatin, but not glucose. Archives in General Psychiatry. 56:1999;1135-1140.
7. Craft S., Asthana S., Schellenberg G.D., Cherrier M., Baker L.D., Newcomer J., Plymate S., Latendresse S., Petrova A., Lofgreen C., Grimwood K., Raskind M., Peskind E. Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype. Neuroendocrinology. 70:1999;146-152.
8. Craft S., Asthana S., Schellenberg G., Baker L., Cherrier M., Boyt A.A., Martins R.N., Raskind M., Peskind E., Plymate S. Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype. Annals of the New York Academy of Sciences. 903:2000;222-228.
9. Craft S., Zallen G., Baker L.D. Glucose and memory in mild senile dementia of the Alzheimer's type. Journal of Clinical and Experimental Neuropsychology. 14:1992;253-267.
10. Craft S., Dagogo-Jack S., Wiethop B., Murphy C., Nevins R., Fleischman S., Rice V., Newcomber J., Cryer P.E. The effects of hyperglycemia on memory and hormone levels in mild senile dementia of the Alzheimer's type: a longitudinal study. Behavioral Neuroscience. 107:(6):1993;926-940.
11. Craft S., Newcomer J., Kanne S., Dagogo-Jack S., Cryer P.E., Sheline Y., Luby J., Dagogo-Jack A., Alderson A. Memory improvement following induced hyperinsulinemia in dementia of the Alzheimer type. Neurobiology of Aging. 17:1996;123-130.
12. Craft S., Peskind E., Schwartz M.W., Schellenberg G.D., Raskind M., Porte D. Jr. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E gentotype. Neurology. 50:1998;164-168.
13. Descamps O., Bilheimer D., Herz J. Insulin stimulates receptor-mediated uptake of apoE-enriched lipoproteins and activated a2-macroglobulin in adipocytes. Journal of Biological Chemistry. 268:(2):1993;974-981.
14. Edbauer D., Willem M., Lammich S., Steiner H., Haass C. Insulin degrading enzyme rapidly removes the B-amyloid precursor protein intracellular domain (AICD). Journal of Biological Chemistry. 277:2002;13,389-393.
15. Emi M., Wu L.L., Robertson M.A., Myers R.L., Hegele R.A., Williams R.R., White R., Lalouel J.M. Genotyping and sequence analysis of apolipoprotein E isoforms. Genomics. 3:(4):1988;373-379.
16. Folli F., Ghidella S., Bonfanti L., Kahn C.R., Merighi A. The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system. Molecular Neurobiology. 13:(2):1996;155-183.
17. Gasparini L., Gouras G.K., Wang R., Gross R.S., Beal M.F., Greengard P., Xu H. Stimulation of B-amyloid precursor protein trafficking by insulin reduces intraneuronal B-amyloid and requires mitogen-activated protein kinase signaling. Journal of Neuroscience. 21:(8):2001;2561-2570.
18. Hixson J.E., Vernier D.T. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hhal. Journal of Lipid Research. 31:(3):1990;545-548.
19. Kounnas M.Z., Moir R.D., Rebeck G.W., Bush A.I., Argraves W.S., Tanzi R.E., Hyman B.T., Strickland D.K. LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell. 82:(2):1995;331-340.
20. Leibson C.L., Rocca W.A., Hanson V.A., Cha R., Kokmen E., O'Brien P.C., Palumbo P.J. Risk of dementia among persons with diabetes mellitus: a population-based cohort. American Journal of Epidemiology. 145:1997;301-308.
21. Manning C., Ragozzino M., Gold P.E. Glucose enhancement of memory in patients with probable senile dementia of the Alzheimer's type. Neurobiology of Aging. 14:1993;523.
22. Marks J.L., King M.G., Baskin D.G. Localization of insulin and type 1 IGF receptors in rat brain by in vitro autoradiography and in situ hybridization. Raizada M.K., LeRoith D. Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors. 1991;459-470 Plenum Press, New York.
23. Mattis, S., 1988. Dementia rating scale. Psychological Assessment Resources.
24. McKhann G., Drachman D., Folstein M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology. 34:(7):1984;939-944.
25. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Research. 16:(3):1988;1215.
26. Moscovitch M. Cognitive resources and dual-task interference effects on retrieval in normal people: the role of the frontal lobe and medial temporal cortex. Neuropsychology. 8:1994;524-534.
27. Ott A., Stolk R.P., Hofman A., van Harskamp F., Grobbee D.E., Breteler M.M.B. Association of diabetes mellitus and dementia: the Rotterdam study. Diabetologia. 39:1996;1392-1397.
28. Peila R., Rodriguez B., Launer L. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies. Diabetes. 51:(April):2002;1256-1262.
29. Perret E. The left frontal lobe of man and the suppression of habitual responses in verbal categorical behavior. Neuropsychologia. 12:1974;323-330.
30. Qiu W.Q., Waslh D., Ye Z., Konstantinos V., Zhang J., Podlisny M.B., Rosner M.R., Safavi A., Hersh L.B., Selkoe D.J. Insulin-degrading enzyme regulates extracellular levels of amyloid B-protein by degradation. Journal of Biological Chemistry. 273:(49):1998;32730-32738.
31. Schwartz M.W., Figlewicz D.F., Kahn S.E., Baskin D.G., Greenwood M.R., Porte D.J. Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats. Peptides. 11:(3):1990;467-472.
32. Solano D.C., Sironi M., Bonfini C., Solerte S.B., Govini S., Racchi M. Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway. FASEB Journal. 14:2000;1015-1022.
33. Stein L.J., Dorsa D., Baskin D.G., Figlewicz D.P., Porte D.J., Woods S.C. Reduced effect of experimental peripheral hyperinsulinemia to elevate cerebrospinal fluid insulin concentrations of obese Zucker rats. Endocrinology. 121:(5):1987;1611-1615.
34. Storandt M., Hill R.D. Very mild senile dementia of the Alzheimer's type II. Psychometric test performance. Archives of Neurology. 46:1989;383.
35. Vekrellis K., Ye Z., Qiu W.Q., Walsh D., Hartley D., Chesneau V., Rosner M.R., Selkoe D.J. Neurons regulate extracellular levels of amyloid B-protein via proteolysis by insulin-degrading enzyme. Journal of Neuroscience. 20:(5):2000;1657-1665.
36. Xie L., Helmerhorst E., Taddei K., Plewright B., van Bronswijk W., Martins R. Alzheimer's β-amyloid peptides compete for insulin binding to the insulin receptor. The Journal of Neuroscience. 22:2002;5.