메뉴 건너뛰기




Volumn 190, Issue 2, 2006, Pages 191-202

Endocrine signaling in Caenorhabditis elegans controls stress response and longevity

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK TRANSCRIPTION FACTOR 1; HORMONE RECEPTOR; INSULIN; REACTIVE OXYGEN METABOLITE; RESVERATROL; SILENT INFORMATION REGULATOR PROTEIN 2; SOMATOMEDIN C RECEPTOR; STEROID HORMONE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR SKN 1; UNCLASSIFIED DRUG;

EID: 33747880238     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.06856     Document Type: Review
Times cited : (150)

References (109)
  • 1
    • 0347854376 scopus 로고    scopus 로고
    • Regulation of C. elegans longevity by specific gustatory and olfactory neurons
    • Alcedo J & Kenyon C 2004 Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron 41 45-55.
    • (2004) Neuron , vol.41 , pp. 45-55
    • Alcedo, J.1    Kenyon, C.2
  • 2
    • 0042626242 scopus 로고    scopus 로고
    • SKN-1 links C. elegans mesenclodermal specification to a conserved oxidative stress response
    • An JH & Blackwell TK 2003 SKN-1 links C. elegans mesenclodermal specification to a conserved oxidative stress response. Genes and Development 17 1882 1893.
    • (2003) Genes and Development , vol.17 , pp. 1882-1893
    • An, J.H.1    Blackwell, T.K.2
  • 3
    • 28044446334 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3
    • An JH, Vranas K, Lucke M, Inoue H, Hisamoto N, Matsumoto K & Blackwell TK 2005 Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3. PNAS 102 16275-16280.
    • (2005) PNAS , vol.102 , pp. 16275-16280
    • An, J.H.1    Vranas, K.2    Lucke, M.3    Inoue, H.4    Hisamoto, N.5    Matsumoto, K.6    Blackwell, T.K.7
  • 4
    • 38449116228 scopus 로고    scopus 로고
    • Nuclear hormone receptors in C. elegans
    • In Ed The C. elegans Research Community. doi/10.1895/wormbook.1.64.1
    • Antebi A 2006 Nuclear hormone receptors in C. elegans. In Wormbook, Ed The C. elegans Research Community. doi/10.1895/wormbook.1.64.1, http://wormbook.org.
    • (2006) Wormbook
    • Antebi, A.1
  • 5
    • 0034659485 scopus 로고    scopus 로고
    • Daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans
    • Antebi A, Yeh WH, Tait D, Hedgecock EM & R-iddle DL 2000 daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes and Development 14 1512-1527.
    • (2000) Genes and Development , vol.14 , pp. 1512-1527
    • Antebi, A.1    Yeh, W.H.2    Tait, D.3    Hedgecock, E.M.4    R-iddle, D.L.5
  • 6
    • 0033576579 scopus 로고    scopus 로고
    • Regulation of lifespan by sensory perception in Caenorhabditis elegans
    • Apfeld J & Kenyon C 1999 Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402 804-809.
    • (1999) Nature , vol.402 , pp. 804-809
    • Apfeld, J.1    Kenyon, C.2
  • 7
    • 0037127026 scopus 로고    scopus 로고
    • Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
    • Arantes-Oliveira N, Apfeld J, Dillin A & Kenyon C 2002 Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 295 502-505.
    • (2002) Science , vol.295 , pp. 502-505
    • Arantes-Oliveira, N.1    Apfeld, J.2    Dillin, A.3    Kenyon, C.4
  • 9
    • 0026419552 scopus 로고
    • Control oflarval development by chemosensory neurons in Caenorhabditis elegans
    • Bargmann CI & Horvitz FIR 1991 Control oflarval development by chemosensory neurons in Caenorhabditis elegans. Science 251 1243-1246.
    • (1991) Science , vol.251 , pp. 1243-1246
    • Bargmann, C.I.1    Horvitz, F.I.R.2
  • 10
    • 33646057039 scopus 로고    scopus 로고
    • Indicted: Worms caught using steroids
    • Beckstead RB & Thummel CS 2006 Indicted: worms caught using steroids. Cell 124 1137-1140.
    • (2006) Cell , vol.124 , pp. 1137-1140
    • Beckstead, R.B.1    Thummel, C.S.2
  • 11
    • 33644772542 scopus 로고    scopus 로고
    • Germ-cell loss extends C. elegans, life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling
    • Berman JR & Kenyon C 2006 Germ-cell loss extends C. elegans, life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. Cell 124 1055-1068.
    • (2006) Cell , vol.124 , pp. 1055-1068
    • Berman, J.R.1    Kenyon, C.2
  • 12
    • 17144429302 scopus 로고    scopus 로고
    • Calorie restriction SIRT1 and metabolism: Understanding longevity
    • Bordone L & Guarente L 2005 Calorie restriction SIRT1 and metabolism: understanding longevity. Nature Reviews Molecular Cell Biology 6 298-305.
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , pp. 298-305
    • Bordone, L.1    Guarente, L.2
  • 15
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S 1974 The genetics of Caenorhabditis elegans. Genetics 77 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 16
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHR-L1 (FOX03a)
    • Brunet A, Park J, Tran H, Hu LS, Hemmings BA & Greenberg ME 2001 Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHR-L1 (FOX03a). Molecular Cell Biology 21 952-965.
    • (2001) Molecular Cell Biology , vol.21 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3    Hu, L.S.4    Hemmings, B.A.5    Greenberg, M.E.6
  • 18
    • 0032401041 scopus 로고    scopus 로고
    • C. elegans neuroscience: Genetics to genome
    • Chalfie M & Jorgensen EMC 1998 C. elegans neuroscience: genetics to genome. Trends Genetics 14 506-512.
    • (1998) Trends Genetics , vol.14 , pp. 506-512
    • Chalfie, M.1    Jorgensen, E.M.C.2
  • 20
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans, by the TIR, domain adaptor protein TIR-1, an ortholog of human SARM
    • Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y & Ewbank JJ 2004 TLR-independent control of innate immunity in Caenorhabditis elegans, by the TIR, domain adaptor protein TIR-1, an ortholog of human SARM. Nature Immunology 5 488-494.
    • (2004) Nature Immunology , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.F.5    Kohara, Y.6    Ewbank, J.J.7
  • 21
    • 3042750643 scopus 로고    scopus 로고
    • Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
    • Daitoku H, Hatta M, Matsuzaki H, Aratani S, Ohshima T, Miyagishi M, Nakajima T & Fukamizu A 2004 Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. PNAS 101 10042-10047.
    • (2004) PNAS , vol.101 , pp. 10042-10047
    • Daitoku, H.1    Hatta, M.2    Matsuzaki, H.3    Aratani, S.4    Ohshima, T.5    Miyagishi, M.6    Nakajima, T.7    Fukamizu, A.8
  • 22
    • 0242363670 scopus 로고    scopus 로고
    • Molecular pathways of neurodegeneration in Parkinson's disease
    • Dawson TM & Dawson VL 2003 Molecular pathways of neurodegeneration in Parkinson's disease. Science 302 819-822.
    • (2003) Science , vol.302 , pp. 819-822
    • Dawson, T.M.1    Dawson, V.L.2
  • 25
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE & Mello CC 1998 Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 26
    • 33644798225 scopus 로고    scopus 로고
    • Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan
    • Gami MS & Wolkow CA 2006 Studies of Caenorhabditis elegans DAF-2/ insulin signaling reveal targets for pharmacological manipulation of lifespan. Aging Cell 5 31-37.
    • (2006) Aging Cell , vol.5 , pp. 31-37
    • Gami, M.S.1    Wolkow, C.A.2
  • 27
    • 2342420089 scopus 로고    scopus 로고
    • Hormonal signals produced by DAF-9/ cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues
    • Gerisch B & Antebi A 2004 Hormonal signals produced by DAF-9/ cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues. Development 131 1765-1776.
    • (2004) Development , vol.131 , pp. 1765-1776
    • Gerisch, B.1    Antebi, A.2
  • 28
    • 0035656274 scopus 로고    scopus 로고
    • A hormonal signaling pathway influencing C. elegans metabolism reproductive development, and life span
    • Gerisch B, Weitzel C, Kober-Eisermarm C, Rottiers V & Antebi A 2001 A hormonal signaling pathway influencing C. elegans metabolism reproductive development, and life span. Developmental Cell 1 841-851.
    • (2001) Developmental Cell , vol.1 , pp. 841-851
    • Gerisch, B.1    Weitzel, C.2    Kober-Eisermarm, C.3    Rottiers, V.4    Antebi, A.5
  • 30
    • 0028334880 scopus 로고
    • daf-2, daf- 16 and daf-23: Genetically interacting genes controlling dauer formation in Caenorhabditis elegans
    • Gottlieb S & Ruvkun G 1994 daf-2, daf- 16 and daf-23: genetically interacting genes controlling dauer formation in Caenorhabditis elegans. Genetics 137 107-120.
    • (1994) Genetics , vol.137 , pp. 107-120
    • Gottlieb, S.1    Ruvkun, G.2
  • 32
    • 11244344049 scopus 로고    scopus 로고
    • The L-type cyclin CYL-1 and the heat-shock-factor HSF-1 are required for heat-shock-induced protein expression in Caenorhabditis elegans
    • Hajdu-Cronin YM, Chen WJ & Sternberg PW 2004 The L-type cyclin CYL-1 and the heat-shock-factor HSF-1 are required for heat-shock-induced protein expression in Caenorhabditis elegans. Genetics 168 1937-1949.
    • (2004) Genetics , vol.168 , pp. 1937-1949
    • Hajdu-Cronin, Y.M.1    Chen, W.J.2    Sternberg, P.W.3
  • 35
    • 33645472504 scopus 로고    scopus 로고
    • New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Coenorhabditis elegans genomic RNAi screen
    • Hansen M, Hsu AL, Dillin A & Kenyon C 2005 New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Coenorhabditis elegans genomic RNAi screen. PLoS Genetics 1 119-128.
    • (2005) PLoS Genetics , vol.1 , pp. 119-128
    • Hansen, M.1    Hsu, A.L.2    Dillin, A.3    Kenyon, C.4
  • 36
    • 0037470539 scopus 로고    scopus 로고
    • Genetics and the specificity of the aging process
    • Hekimi S & Guarente L 2003 Genetics and the specificity of the aging process. Science 299 1351-1354.
    • (2003) Science , vol.299 , pp. 1351-1354
    • Hekimi, S.1    Guarente, L.2
  • 38
    • 11144355021 scopus 로고    scopus 로고
    • C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span
    • Hertweck M, Gobel C & Baumeister R 2004 C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Developmental Cell 6 577-588.
    • (2004) Developmental Cell , vol.6 , pp. 577-588
    • Hertweck, M.1    Gobel, C.2    Baumeister, R.3
  • 39
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • Honda Y & Honda S 1999 The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB Journal 13 1385-1393.
    • (1999) FASEB Journal , vol.13 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 41
    • 0033609291 scopus 로고    scopus 로고
    • Signals from the reproductive system regulate the lifespan of C elegans
    • Hsin H & Kenyon C 1999 Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399 362-366.
    • (1999) Nature , vol.399 , pp. 362-366
    • Hsin, H.1    Kenyon, C.2
  • 42
    • 0038701745 scopus 로고    scopus 로고
    • Regulation of aging and age-related disease by DAF-16 and heat-shock factor
    • Hsu AL, Murphy CT & Kenyon C 2003 Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300 1142-1145.
    • (2003) Science , vol.300 , pp. 1142-1145
    • Hsu, A.L.1    Murphy, C.T.2    Kenyon, C.3
  • 43
    • 0345073631 scopus 로고    scopus 로고
    • A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor
    • Hua QX, Nakagawa SH, Wilken J, Ramos RR, Jia W, Bass J & Weiss MA 2003 A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor. Genes and Development 17 826-831.
    • (2003) Genes and Development , vol.17 , pp. 826-831
    • Hua, Q.X.1    Nakagawa, S.H.2    Wilken, J.3    Ramos, R.R.4    Jia, W.5    Bass, J.6    Weiss, M.A.7
  • 44
    • 2542643174 scopus 로고    scopus 로고
    • Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans
    • Huang C, Xiong C & Kornfeld K 2004 Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. PNAS 101 8084-9089.
    • (2004) PNAS , vol.101 , pp. 8084-9089
    • Huang, C.1    Xiong, C.2    Kornfeld, K.3
  • 45
    • 25844490465 scopus 로고    scopus 로고
    • The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response
    • Inoue H, Hisamoto N, An JH, Oliveira RP Nishida E, Blackwell TK & Matsumoto K 2005 The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes and Development 19 2278-2283.
    • (2005) Genes and Development , vol.19 , pp. 2278-2283
    • Inoue, H.1    Hisamoto, N.2    An, J.H.3    Oliveira, R.P.4    Nishida, E.5    Blackwell, T.K.6    Matsumoto, K.7
  • 47
    • 0036333147 scopus 로고    scopus 로고
    • 2002 DAF-9 a cytochrome P450 regulating C. elegans larval development and adult longevity
    • Jia K, Albert PS & Riddle DL 2002 DAF-9 a cytochrome P450 regulating C. elegans larval development and adult longevity. Development 129 221-231.
    • Development , vol.129 , pp. 221-231
    • Jia, K.1    Albert, P.S.2    Riddle, D.L.3
  • 48
    • 4544311861 scopus 로고    scopus 로고
    • The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
    • Jia K, Chen D & Riddle D 2004a The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131 3897-3906.
    • (2004) Development , vol.131 , pp. 3897-3906
    • Jia, K.1    Chen, D.2    Riddle, D.3
  • 49
    • 4544311861 scopus 로고    scopus 로고
    • The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
    • Jia K, Chen D & Riddle DL 2004b The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131 3897-3906.
    • (2004) Development , vol.131 , pp. 3897-3906
    • Jia, K.1    Chen, D.2    Riddle, D.L.3
  • 50
    • 25144496080 scopus 로고    scopus 로고
    • Heritable and inducible gene knockdown in C. elegans using Wormgate and the ORFeome
    • Johnson NM, Behm CA & Trowell SC 2005 Heritable and inducible gene knockdown in C. elegans using Wormgate and the ORFeome. Genetics 359 26-34.
    • (2005) Genetics , vol.359 , pp. 26-34
    • Johnson, N.M.1    Behm, C.A.2    Trowell, S.C.3
  • 54
    • 3042648746 scopus 로고    scopus 로고
    • Regulation of lifespan in Drosophila by modulation of genes in the TOR, signaling pathway
    • Kapahi P, Zid BM, Harper T, Koslover D, Sapin V & Benzer S 2004 Regulation of lifespan in Drosophila by modulation of genes in the TOR, signaling pathway. Current Biology 14 885-890.
    • (2004) Current Biology , vol.14 , pp. 885-890
    • Kapahi, P.1    Zid, B.M.2    Harper, T.3    Koslover, D.4    Sapin, V.5    Benzer, S.6
  • 55
    • 0024283243 scopus 로고
    • The nematode Caenorhabditis elegans
    • Kenyon C 1988 The nematode Caenorhabditis elegans. Science 240 1448-1453.
    • (1988) Science , vol.240 , pp. 1448-1453
    • Kenyon, C.1
  • 56
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: Insights from long-lived mutants
    • Kenyon C 2005 The plasticity of aging: insights from long-lived mutants. Cell 120 449-460.
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 57
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C, Chang J, Gensch E, Rudner A & Tabtiang R 1993 A C. elegans mutant that lives twice as long as wild type. Nature 366 461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 58
    • 0032573178 scopus 로고    scopus 로고
    • The genetics of caloric restriction in Caenorhabditis elegans
    • Lakowski B & Hekimi S 1998 The genetics of caloric restriction in Caenorhabditis elegans. PNAS 95 13091-13096.
    • (1998) PNAS , vol.95 , pp. 13091-13096
    • Lakowski, B.1    Hekimi, S.2
  • 59
    • 0035846601 scopus 로고    scopus 로고
    • Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
    • Lee RY, Hench J & Ruvkun G 2001 Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Current Biology 11 1950-1957.
    • (2001) Current Biology , vol.11 , pp. 1950-1957
    • Lee, R.Y.1    Hench, J.2    Ruvkun, G.3
  • 60
    • 0037228016 scopus 로고    scopus 로고
    • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
    • Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J & Ruvkun G 2003 A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nature Genetics 33 40-48.
    • (2003) Nature Genetics , vol.33 , pp. 40-48
    • Lee, S.S.1    Lee, R.Y.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Ruvkun, G.6
  • 62
    • 0037380570 scopus 로고    scopus 로고
    • daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway
    • Li W, Kennedy SG & Ruvkun G 2003 daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. Genes and Development 17 844-858.
    • (2003) Genes and Development , vol.17 , pp. 844-858
    • Li, W.1    Kennedy, S.G.2    Ruvkun, G.3
  • 63
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C. clegans DAF-16 in the regulation of lifespan
    • Libina N, Berman JR & Kenyon C 2003 Tissue-specific activities of C. clegans DAF-16 in the regulation of lifespan. Cell 115 489-502.
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 64
    • 0034967720 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
    • Lin K, Hsin H, Libina N & Kenyon C 2001 Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nature Genetics 28 139-145.
    • (2001) Nature Genetics , vol.28 , pp. 139-145
    • Lin, K.1    Hsin, H.2    Libina, N.3    Kenyon, C.4
  • 66
    • 2342428206 scopus 로고    scopus 로고
    • Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450
    • Mak HY & Ruvkun G 2004 Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450. Development 131 1777-1786.
    • (2004) Development , vol.131 , pp. 1777-1786
    • Mak, H.Y.1    Ruvkun, G.2
  • 69
    • 0042631524 scopus 로고    scopus 로고
    • Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
    • McElwee J, Bubb K & Thomas JH 2003 Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2 111-121.
    • (2003) Aging Cell , vol.2 , pp. 111-121
    • McElwee, J.1    Bubb, K.2    Thomas, J.H.3
  • 70
    • 7244238167 scopus 로고    scopus 로고
    • Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
    • McElwee JJ, Schuster E, Blanc E, Thomas JH & Gems D 2004 Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. Journal of Biological Chemistry 279 44533-44543.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 44533-44543
    • McElwee, J.J.1    Schuster, E.2    Blanc, E.3    Thomas, J.H.4    Gems, D.5
  • 71
    • 4344632329 scopus 로고    scopus 로고
    • Deletion ofthe intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans
    • Meissner B, Boll M, Daniel H & Baumeister R 2004 Deletion ofthe intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans. Journal of Biological Chemistry 279 36739-36745.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 36739-36745
    • Meissner, B.1    Boll, M.2    Daniel, H.3    Baumeister, R.4
  • 73
    • 0742323000 scopus 로고    scopus 로고
    • Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones
    • Morley JF & Morimoto RI 2004 Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Molecular Biology of the Cell 15 657-664.
    • (2004) Molecular Biology of the Cell , vol.15 , pp. 657-664
    • Morley, J.F.1    Morimoto, R.I.2
  • 74
    • 0029768753 scopus 로고    scopus 로고
    • A phosphatidyhnositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
    • Morris JZ, Tissenbaum HA & Ruvkun G 1996 A phosphatidyhnositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382 536-539.
    • (1996) Nature , vol.382 , pp. 536-539
    • Morris, J.Z.1    Tissenbaum, H.A.2    Ruvkun, G.3
  • 76
    • 27244443371 scopus 로고    scopus 로고
    • C. elegans tubby regulates life span and fat storage by two independent mechanisms
    • Mukhopadhyay A, Deplancke B, Walhout AJ & Tissenbaum HA 2005 C. elegans tubby regulates life span and fat storage by two independent mechanisms. Cell Metabolism 2 35-42.
    • (2005) Cell Metabolism , vol.2 , pp. 35-42
    • Mukhopadhyay, A.1    Deplancke, B.2    Walhout, A.J.3    Tissenbaum, H.A.4
  • 78
    • 0032238299 scopus 로고    scopus 로고
    • The C. elegans; PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
    • Ogg S & Ruvkun G 1998 The C. elegans; PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. Molecular Cell 2 887-893.
    • (1998) Molecular Cell , vol.2 , pp. 887-893
    • Ogg, S.1    Ruvkun, G.2
  • 79
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA & Ruvkun G 1997 The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389 994-999.
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5    Tissenbaum, H.A.6    Ruvkun, G.7
  • 80
    • 15444371989 scopus 로고    scopus 로고
    • JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
    • Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ & Tissenbaum HA 2005 JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. PNAS 102 4494-4499.
    • (2005) PNAS , vol.102 , pp. 4494-4499
    • Oh, S.W.1    Mukhopadhyay, A.2    Svrzikapa, N.3    Jiang, F.4    Davis, R.J.5    Tissenbaum, H.A.6
  • 81
    • 0032529189 scopus 로고    scopus 로고
    • Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
    • Paradis S & Ruvkun G 1998 Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes and Development 12 2488-2498.
    • (1998) Genes and Development , vol.12 , pp. 2488-2498
    • Paradis, S.1    Ruvkun, G.2
  • 82
    • 0033151613 scopus 로고    scopus 로고
    • A PDK1 homolog is necessary and sufficient to transduce AGE-1 P13 kinase signals that regulate diapause in Caenorhabditis elegans
    • Paradis S, Ailion M, Toker A, Thomas JH & Ruvkun G 1999 A PDK1 homolog is necessary and sufficient to transduce AGE-1 P13 kinase signals that regulate diapause in Caenorhabditis elegans. Genes and Development 13 1438-1452.
    • (1999) Genes and Development , vol.13 , pp. 1438-1452
    • Paradis, S.1    Ailion, M.2    Toker, A.3    Thomas, J.H.4    Ruvkun, G.5
  • 85
    • 23044445756 scopus 로고    scopus 로고
    • A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
    • Rea SL, Wu D, Cypser JR, Vaupel JW & Johnson TE 2005 A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nature Genetics 37 894-898.
    • (2005) Nature Genetics , vol.37 , pp. 894-898
    • Rea, S.L.1    Wu, D.2    Cypser, J.R.3    Vaupel, J.W.4    Johnson, T.E.5
  • 88
    • 0036710840 scopus 로고    scopus 로고
    • Mammalian peptide transporters as targets for drug delivery
    • Rubio-Aliaga I & Daniel H 2002 Mammalian peptide transporters as targets for drug delivery. Trends in Pharmacology Science 23 434-440.
    • (2002) Trends in Pharmacology Science , vol.23 , pp. 434-440
    • Rubio-Aliaga, I.1    Daniel, H.2
  • 89
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • Schmelzle T & Hall MN 2000 TOR, a central controller of cell growth. Cell 103 253-262.
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 90
    • 0034670132 scopus 로고    scopus 로고
    • Structure and expression of daf-12: A nuclear hormone receptor with three isoforms that are involved in development and aging in Caenorhabditis elegans
    • Snow MI & Larsen PL 2000 Structure and expression of daf-12: a nuclear hormone receptor with three isoforms that are involved in development and aging in Caenorhabditis elegans. Biochimica et Biophysica Acta 1494 104-116.
    • (2000) Biochimica Et Biophysica Acta , vol.1494 , pp. 104-116
    • Snow, M.I.1    Larsen, P.L.2
  • 91
    • 0031468610 scopus 로고    scopus 로고
    • Analysis of protein domain families in Caenorhabditis elegans
    • Sonnhammer EL & Durbin R 1997 Analysis of protein domain families in Caenorhabditis elegans. Genomics 46 200-216.
    • (1997) Genomics , vol.46 , pp. 200-216
    • Sonnhammer, E.L.1    Durbin, R.2
  • 92
    • 27944506923 scopus 로고    scopus 로고
    • A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress
    • Springer W, Hoppe T, Schmidt E & Baumeister R 2005 A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress. Human Molecular Genetics 14 3407-3423.
    • (2005) Human Molecular Genetics , vol.14 , pp. 3407-3423
    • Springer, W.1    Hoppe, T.2    Schmidt, E.3    Baumeister, R.4
  • 94
    • 0037470501 scopus 로고    scopus 로고
    • The endocrine regulation of aging by insuhn-like signals
    • Tatar M, Bartke A & Antebi A 2003 The endocrine regulation of aging by insuhn-like signals. Science 299 1346-1351.
    • (2003) Science , vol.299 , pp. 1346-1351
    • Tatar, M.1    Bartke, A.2    Antebi, A.3
  • 95
    • 0033968037 scopus 로고    scopus 로고
    • Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
    • Tavernarakis N, Wang SL, Dorovkov M, Ryazanov A & Driscoll M 2000 Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes. Nature Genetics 24 180-183.
    • (2000) Nature Genetics , vol.24 , pp. 180-183
    • Tavernarakis, N.1    Wang, S.L.2    Dorovkov, M.3    Ryazanov, A.4    Driscoll, M.5
  • 96
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum HA & Guarente L 2001 Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 227-230.
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 99
    • 27644585190 scopus 로고    scopus 로고
    • A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
    • Viswanathan M, Kim SK, Berdichevsky A & Guarente L 2005 A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Development and Cell 9 605-615.
    • (2005) Development and Cell , vol.9 , pp. 605-615
    • Viswanathan, M.1    Kim, S.K.2    Berdichevsky, A.3    Guarente, L.4
  • 102
    • 28244475950 scopus 로고    scopus 로고
    • Overlapping and distinct functions for a C. elegans SIR2 and DAF-l6/FOXO
    • Wang Y & Tissenbaum HA 2006 Overlapping and distinct functions for a C. elegans SIR2 and DAF-l6/FOXO. Mechanisms ofl Ageing and Development 127 48-56.
    • (2006) Mechanisms of Ageing and Development , vol.127 , pp. 48-56
    • Wang, Y.1    Tissenbaum, H.A.2
  • 104
    • 0034613164 scopus 로고    scopus 로고
    • Regulation of C. elegans life-span by insulin-like signaling in the nervous system
    • Wolkow CA, Kimura KD, Lee MS & Ruvkun G 2000 Regulation of C. elegans life-span by insulin-like signaling in the nervous system. Science 290 147-150.
    • (2000) Science , vol.290 , pp. 147-150
    • Wolkow, C.A.1    Kimura, K.D.2    Lee, M.S.3    Ruvkun, G.4
  • 105
    • 0346668317 scopus 로고    scopus 로고
    • Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway
    • Wolkow C, Munoz M, Riddle D & Ruvkun G 2002 Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway. Journal of Biological Chemistry 277 49591-49597.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 49591-49597
    • Wolkow, C.1    Munoz, M.2    Riddle, D.3    Ruvkun, G.4
  • 106
    • 31744438846 scopus 로고    scopus 로고
    • Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
    • Wook Oh S, Mukhopadhyay A, Dixit BL, Raha T, Green MR & Tissenbaum HA 2006 Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nature Genetics 38 251-257.
    • (2006) Nature Genetics , vol.38 , pp. 251-257
    • Wook Oh, S.1    Mukhopadhyay, A.2    Dixit, B.L.3    Raha, T.4    Green, M.R.5    Tissenbaum, H.A.6
  • 107
    • 16344384026 scopus 로고    scopus 로고
    • Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
    • Yang Y, Hou H, Haller EM, Nicosia SV & Bai W 2005a Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO Journal 24 1021-1032.
    • (2005) EMBO Journal , vol.24 , pp. 1021-1032
    • Yang, Y.1    Hou, H.2    Haller, E.M.3    Nicosia, S.V.4    Bai, W.5
  • 108
    • 26444489693 scopus 로고    scopus 로고
    • Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
    • Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S et al. 2005b Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. PNAS 102 13670-13675.
    • (2005) PNAS , vol.102 , pp. 13670-13675
    • Yang, Y.1    Gehrke, S.2    Haque, M.E.3    Imai, Y.4    Kosek, J.5    Yang, L.6    Beal, M.F.7    Nishimura, I.8    Wakamatsu, K.9    Ito, S.10
  • 109
    • 0026726186 scopus 로고
    • Protein oxidation associated with aging is reduced by dietary restriction of protein or calories
    • Youngman LD, Park JY & Ames BN 1992 Protein oxidation associated with aging is reduced by dietary restriction of protein or calories. PNAS 89 9112-9116.
    • (1992) PNAS , vol.89 , pp. 9112-9116
    • Youngman, L.D.1    Park, J.Y.2    Ames, B.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.