-
1
-
-
0347854376
-
Regulation of C. elegans longevity by specific gustatory and olfactory neurons
-
Alcedo J & Kenyon C 2004 Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron 41 45-55.
-
(2004)
Neuron
, vol.41
, pp. 45-55
-
-
Alcedo, J.1
Kenyon, C.2
-
2
-
-
0042626242
-
SKN-1 links C. elegans mesenclodermal specification to a conserved oxidative stress response
-
An JH & Blackwell TK 2003 SKN-1 links C. elegans mesenclodermal specification to a conserved oxidative stress response. Genes and Development 17 1882 1893.
-
(2003)
Genes and Development
, vol.17
, pp. 1882-1893
-
-
An, J.H.1
Blackwell, T.K.2
-
3
-
-
28044446334
-
Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3
-
An JH, Vranas K, Lucke M, Inoue H, Hisamoto N, Matsumoto K & Blackwell TK 2005 Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3. PNAS 102 16275-16280.
-
(2005)
PNAS
, vol.102
, pp. 16275-16280
-
-
An, J.H.1
Vranas, K.2
Lucke, M.3
Inoue, H.4
Hisamoto, N.5
Matsumoto, K.6
Blackwell, T.K.7
-
4
-
-
38449116228
-
Nuclear hormone receptors in C. elegans
-
In Ed The C. elegans Research Community. doi/10.1895/wormbook.1.64.1
-
Antebi A 2006 Nuclear hormone receptors in C. elegans. In Wormbook, Ed The C. elegans Research Community. doi/10.1895/wormbook.1.64.1, http://wormbook.org.
-
(2006)
Wormbook
-
-
Antebi, A.1
-
5
-
-
0034659485
-
Daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans
-
Antebi A, Yeh WH, Tait D, Hedgecock EM & R-iddle DL 2000 daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes and Development 14 1512-1527.
-
(2000)
Genes and Development
, vol.14
, pp. 1512-1527
-
-
Antebi, A.1
Yeh, W.H.2
Tait, D.3
Hedgecock, E.M.4
R-iddle, D.L.5
-
6
-
-
0033576579
-
Regulation of lifespan by sensory perception in Caenorhabditis elegans
-
Apfeld J & Kenyon C 1999 Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402 804-809.
-
(1999)
Nature
, vol.402
, pp. 804-809
-
-
Apfeld, J.1
Kenyon, C.2
-
7
-
-
0037127026
-
Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
-
Arantes-Oliveira N, Apfeld J, Dillin A & Kenyon C 2002 Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 295 502-505.
-
(2002)
Science
, vol.295
, pp. 502-505
-
-
Arantes-Oliveira, N.1
Apfeld, J.2
Dillin, A.3
Kenyon, C.4
-
8
-
-
0037448528
-
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
-
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J & Ruvkun G 2003 Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421 268-272.
-
(2003)
Nature
, vol.421
, pp. 268-272
-
-
Ashrafi, K.1
Chang, F.Y.2
Watts, J.L.3
Fraser, A.G.4
Kamath, R.S.5
Ahringer, J.6
Ruvkun, G.7
-
9
-
-
0026419552
-
Control oflarval development by chemosensory neurons in Caenorhabditis elegans
-
Bargmann CI & Horvitz FIR 1991 Control oflarval development by chemosensory neurons in Caenorhabditis elegans. Science 251 1243-1246.
-
(1991)
Science
, vol.251
, pp. 1243-1246
-
-
Bargmann, C.I.1
Horvitz, F.I.R.2
-
10
-
-
33646057039
-
Indicted: Worms caught using steroids
-
Beckstead RB & Thummel CS 2006 Indicted: worms caught using steroids. Cell 124 1137-1140.
-
(2006)
Cell
, vol.124
, pp. 1137-1140
-
-
Beckstead, R.B.1
Thummel, C.S.2
-
11
-
-
33644772542
-
Germ-cell loss extends C. elegans, life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling
-
Berman JR & Kenyon C 2006 Germ-cell loss extends C. elegans, life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. Cell 124 1055-1068.
-
(2006)
Cell
, vol.124
, pp. 1055-1068
-
-
Berman, J.R.1
Kenyon, C.2
-
12
-
-
17144429302
-
Calorie restriction SIRT1 and metabolism: Understanding longevity
-
Bordone L & Guarente L 2005 Calorie restriction SIRT1 and metabolism: understanding longevity. Nature Reviews Molecular Cell Biology 6 298-305.
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, pp. 298-305
-
-
Bordone, L.1
Guarente, L.2
-
14
-
-
9244251118
-
Caenorhabdifis elegans MPP + model of Parkinson's disease for high-throughput drug screenings
-
Braungart E, Gerlach M, Riederer F, Baumeister R & Höner M 2004 Caenorhabdifis elegans MPP + model of Parkinson's disease for high-throughput drug screenings. Neurodegenerative Diseases 1 175-183.
-
(2004)
Neurodegenerative Diseases
, vol.1
, pp. 175-183
-
-
Braungart, E.1
Gerlach, M.2
Riederer, F.3
Baumeister, R.4
Höner, M.5
-
15
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S 1974 The genetics of Caenorhabditis elegans. Genetics 77 71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
16
-
-
0035135841
-
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHR-L1 (FOX03a)
-
Brunet A, Park J, Tran H, Hu LS, Hemmings BA & Greenberg ME 2001 Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHR-L1 (FOX03a). Molecular Cell Biology 21 952-965.
-
(2001)
Molecular Cell Biology
, vol.21
, pp. 952-965
-
-
Brunet, A.1
Park, J.2
Tran, H.3
Hu, L.S.4
Hemmings, B.A.5
Greenberg, M.E.6
-
18
-
-
0032401041
-
C. elegans neuroscience: Genetics to genome
-
Chalfie M & Jorgensen EMC 1998 C. elegans neuroscience: genetics to genome. Trends Genetics 14 506-512.
-
(1998)
Trends Genetics
, vol.14
, pp. 506-512
-
-
Chalfie, M.1
Jorgensen, E.M.C.2
-
19
-
-
0037066518
-
Dietary restriction in long-lived dwarf flies
-
Clancy DJ, Gems D, Hafen E, Leevers SJ & Partridge L 2002 Dietary restriction in long-lived dwarf flies. Science 296 319.
-
(2002)
Science
, vol.296
, pp. 319
-
-
Clancy, D.J.1
Gems, D.2
Hafen, E.3
Leevers, S.J.4
Partridge, L.5
-
20
-
-
2442664007
-
TLR-independent control of innate immunity in Caenorhabditis elegans, by the TIR, domain adaptor protein TIR-1, an ortholog of human SARM
-
Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y & Ewbank JJ 2004 TLR-independent control of innate immunity in Caenorhabditis elegans, by the TIR, domain adaptor protein TIR-1, an ortholog of human SARM. Nature Immunology 5 488-494.
-
(2004)
Nature Immunology
, vol.5
, pp. 488-494
-
-
Couillault, C.1
Pujol, N.2
Reboul, J.3
Sabatier, L.4
Guichou, J.F.5
Kohara, Y.6
Ewbank, J.J.7
-
21
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
-
Daitoku H, Hatta M, Matsuzaki H, Aratani S, Ohshima T, Miyagishi M, Nakajima T & Fukamizu A 2004 Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. PNAS 101 10042-10047.
-
(2004)
PNAS
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
Aratani, S.4
Ohshima, T.5
Miyagishi, M.6
Nakajima, T.7
Fukamizu, A.8
-
22
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson TM & Dawson VL 2003 Molecular pathways of neurodegeneration in Parkinson's disease. Science 302 819-822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
23
-
-
18844382368
-
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
-
Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM & Korswagen HC 2005 Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science 308 1181-1184.
-
(2005)
Science
, vol.308
, pp. 1181-1184
-
-
Essers, M.A.1
de Vries-Smits, L.M.2
Barker, N.3
Polderman, P.E.4
Burgering, B.M.5
Korswagen, H.C.6
-
25
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE & Mello CC 1998 Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
26
-
-
33644798225
-
Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan
-
Gami MS & Wolkow CA 2006 Studies of Caenorhabditis elegans DAF-2/ insulin signaling reveal targets for pharmacological manipulation of lifespan. Aging Cell 5 31-37.
-
(2006)
Aging Cell
, vol.5
, pp. 31-37
-
-
Gami, M.S.1
Wolkow, C.A.2
-
27
-
-
2342420089
-
Hormonal signals produced by DAF-9/ cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues
-
Gerisch B & Antebi A 2004 Hormonal signals produced by DAF-9/ cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues. Development 131 1765-1776.
-
(2004)
Development
, vol.131
, pp. 1765-1776
-
-
Gerisch, B.1
Antebi, A.2
-
28
-
-
0035656274
-
A hormonal signaling pathway influencing C. elegans metabolism reproductive development, and life span
-
Gerisch B, Weitzel C, Kober-Eisermarm C, Rottiers V & Antebi A 2001 A hormonal signaling pathway influencing C. elegans metabolism reproductive development, and life span. Developmental Cell 1 841-851.
-
(2001)
Developmental Cell
, vol.1
, pp. 841-851
-
-
Gerisch, B.1
Weitzel, C.2
Kober-Eisermarm, C.3
Rottiers, V.4
Antebi, A.5
-
29
-
-
0033558989
-
Carbonylated proteins in aging and exercise: Inummoblot approaches
-
Goto S, Nakamura A, Radak Z, Nakamoto H, Takahashi R, Yasuda K, Sakurai Y & Ishii N 1999 Carbonylated proteins in aging and exercise: inummoblot approaches. Mechanisms ofAgeing and Development 107 245-253.
-
(1999)
Mechanisms of Ageing and Development
, vol.107
, pp. 245-253
-
-
Goto, S.1
Nakamura, A.2
Radak, Z.3
Nakamoto, H.4
Takahashi, R.5
Yasuda, K.6
Sakurai, Y.7
Ishii, N.8
-
30
-
-
0028334880
-
daf-2, daf- 16 and daf-23: Genetically interacting genes controlling dauer formation in Caenorhabditis elegans
-
Gottlieb S & Ruvkun G 1994 daf-2, daf- 16 and daf-23: genetically interacting genes controlling dauer formation in Caenorhabditis elegans. Genetics 137 107-120.
-
(1994)
Genetics
, vol.137
, pp. 107-120
-
-
Gottlieb, S.1
Ruvkun, G.2
-
31
-
-
0034307463
-
The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress
-
Greeve I, Hermans-Borgmeyer I, Brellinger C, Kasper D, Gomez-Isla T, Behl C, Levkau B & Nitsch RM 2000 The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress. Journal of Neuroscience 20 7345-7352.
-
(2000)
Journal of Neuroscience
, vol.20
, pp. 7345-7352
-
-
Greeve, I.1
Hermans-Borgmeyer, I.2
Brellinger, C.3
Kasper, D.4
Gomez-Isla, T.5
Behl, C.6
Levkau, B.7
Nitsch, R.M.8
-
32
-
-
11244344049
-
The L-type cyclin CYL-1 and the heat-shock-factor HSF-1 are required for heat-shock-induced protein expression in Caenorhabditis elegans
-
Hajdu-Cronin YM, Chen WJ & Sternberg PW 2004 The L-type cyclin CYL-1 and the heat-shock-factor HSF-1 are required for heat-shock-induced protein expression in Caenorhabditis elegans. Genetics 168 1937-1949.
-
(2004)
Genetics
, vol.168
, pp. 1937-1949
-
-
Hajdu-Cronin, Y.M.1
Chen, W.J.2
Sternberg, P.W.3
-
33
-
-
21144460742
-
Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression
-
Halaschek-Wiener J, Khattra JS, McKay S, Pouzyrev A, Stott JM, Yang GS, Holt RA, Jones SJ, Marra MA, Brooks-Wilson AR et al. 2005 Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. Genome Research 15 603-615.
-
(2005)
Genome Research
, vol.15
, pp. 603-615
-
-
Halaschek-Wiener, J.1
Khattra, J.S.2
McKay, S.3
Pouzyrev, A.4
Stott, J.M.5
Yang, G.S.6
Holt, R.A.7
Jones, S.J.8
Marra, M.A.9
Brooks-Wilson, A.R.10
-
34
-
-
22344443522
-
A systematic RNAi screen for longevity genes in C. elegans
-
Hamilton B, Dong Y, Shindo M, Liu W, Odell I, Ruvkun G & Lee SS 2005 A systematic RNAi screen for longevity genes in C. elegans. Genes and Development 19 1544-1555.
-
(2005)
Genes and Development
, vol.19
, pp. 1544-1555
-
-
Hamilton, B.1
Dong, Y.2
Shindo, M.3
Liu, W.4
Odell, I.5
Ruvkun, G.6
Lee, S.S.7
-
35
-
-
33645472504
-
New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Coenorhabditis elegans genomic RNAi screen
-
Hansen M, Hsu AL, Dillin A & Kenyon C 2005 New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Coenorhabditis elegans genomic RNAi screen. PLoS Genetics 1 119-128.
-
(2005)
PLoS Genetics
, vol.1
, pp. 119-128
-
-
Hansen, M.1
Hsu, A.L.2
Dillin, A.3
Kenyon, C.4
-
36
-
-
0037470539
-
Genetics and the specificity of the aging process
-
Hekimi S & Guarente L 2003 Genetics and the specificity of the aging process. Science 299 1351-1354.
-
(2003)
Science
, vol.299
, pp. 1351-1354
-
-
Hekimi, S.1
Guarente, L.2
-
38
-
-
11144355021
-
C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span
-
Hertweck M, Gobel C & Baumeister R 2004 C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Developmental Cell 6 577-588.
-
(2004)
Developmental Cell
, vol.6
, pp. 577-588
-
-
Hertweck, M.1
Gobel, C.2
Baumeister, R.3
-
39
-
-
0032782364
-
The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
-
Honda Y & Honda S 1999 The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB Journal 13 1385-1393.
-
(1999)
FASEB Journal
, vol.13
, pp. 1385-1393
-
-
Honda, Y.1
Honda, S.2
-
40
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL et al. 2003 Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425 191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
-
41
-
-
0033609291
-
Signals from the reproductive system regulate the lifespan of C elegans
-
Hsin H & Kenyon C 1999 Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399 362-366.
-
(1999)
Nature
, vol.399
, pp. 362-366
-
-
Hsin, H.1
Kenyon, C.2
-
42
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu AL, Murphy CT & Kenyon C 2003 Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300 1142-1145.
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
43
-
-
0345073631
-
A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor
-
Hua QX, Nakagawa SH, Wilken J, Ramos RR, Jia W, Bass J & Weiss MA 2003 A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor. Genes and Development 17 826-831.
-
(2003)
Genes and Development
, vol.17
, pp. 826-831
-
-
Hua, Q.X.1
Nakagawa, S.H.2
Wilken, J.3
Ramos, R.R.4
Jia, W.5
Bass, J.6
Weiss, M.A.7
-
44
-
-
2542643174
-
Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans
-
Huang C, Xiong C & Kornfeld K 2004 Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. PNAS 101 8084-9089.
-
(2004)
PNAS
, vol.101
, pp. 8084-9089
-
-
Huang, C.1
Xiong, C.2
Kornfeld, K.3
-
45
-
-
25844490465
-
The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response
-
Inoue H, Hisamoto N, An JH, Oliveira RP Nishida E, Blackwell TK & Matsumoto K 2005 The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes and Development 19 2278-2283.
-
(2005)
Genes and Development
, vol.19
, pp. 2278-2283
-
-
Inoue, H.1
Hisamoto, N.2
An, J.H.3
Oliveira, R.P.4
Nishida, E.5
Blackwell, T.K.6
Matsumoto, K.7
-
46
-
-
0032514466
-
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
-
Ishii N, Fujii M, Hartman, PS, Tsuda M, Yasuda K, Senoo-Matsuda N, Yanase S, Ayusawa D & Suzuki K 1998 A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. Nature 394 694-697.
-
(1998)
Nature
, vol.394
, pp. 694-697
-
-
Ishii, N.1
Fujii, M.2
Hartman, P.S.3
Tsuda, M.4
Yasuda, K.5
Senoo-Matsuda, N.6
Yanase, S.7
Ayusawa, D.8
Suzuki, K.9
-
47
-
-
0036333147
-
2002 DAF-9 a cytochrome P450 regulating C. elegans larval development and adult longevity
-
Jia K, Albert PS & Riddle DL 2002 DAF-9 a cytochrome P450 regulating C. elegans larval development and adult longevity. Development 129 221-231.
-
Development
, vol.129
, pp. 221-231
-
-
Jia, K.1
Albert, P.S.2
Riddle, D.L.3
-
48
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
Jia K, Chen D & Riddle D 2004a The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131 3897-3906.
-
(2004)
Development
, vol.131
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.3
-
49
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
Jia K, Chen D & Riddle DL 2004b The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131 3897-3906.
-
(2004)
Development
, vol.131
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.L.3
-
50
-
-
25144496080
-
Heritable and inducible gene knockdown in C. elegans using Wormgate and the ORFeome
-
Johnson NM, Behm CA & Trowell SC 2005 Heritable and inducible gene knockdown in C. elegans using Wormgate and the ORFeome. Genetics 359 26-34.
-
(2005)
Genetics
, vol.359
, pp. 26-34
-
-
Johnson, N.M.1
Behm, C.A.2
Trowell, S.C.3
-
52
-
-
0242539698
-
The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
-
Junger MA, Rintelen F, Stocker H, Wasserman JD, Vegh M, Radimerski T, Greenberg ME & Hafen E 2003 The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. Journal of Biology 2 20.
-
(2003)
Journal of Biology
, vol.2
, pp. 20
-
-
Junger, M.A.1
Rintelen, F.2
Stocker, H.3
Wasserman, J.D.4
Vegh, M.5
Radimerski, T.6
Greenberg, M.E.7
Hafen, E.8
-
53
-
-
20444431507
-
Substrate-specific activation of sirtuins by resveratrol
-
Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano, PS, Fields S et al. 2005 Substrate-specific activation of sirtuins by resveratrol. Journal of Biological Chemistry 280 17038-17045.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 17038-17045
-
-
Kaeberlein, M.1
McDonagh, T.2
Heltweg, B.3
Hixon, J.4
Westman, E.A.5
Caldwell, S.D.6
Napper, A.7
Curtis, R.8
DiStefano, P.S.9
Fields, S.10
-
54
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR, signaling pathway
-
Kapahi P, Zid BM, Harper T, Koslover D, Sapin V & Benzer S 2004 Regulation of lifespan in Drosophila by modulation of genes in the TOR, signaling pathway. Current Biology 14 885-890.
-
(2004)
Current Biology
, vol.14
, pp. 885-890
-
-
Kapahi, P.1
Zid, B.M.2
Harper, T.3
Koslover, D.4
Sapin, V.5
Benzer, S.6
-
55
-
-
0024283243
-
The nematode Caenorhabditis elegans
-
Kenyon C 1988 The nematode Caenorhabditis elegans. Science 240 1448-1453.
-
(1988)
Science
, vol.240
, pp. 1448-1453
-
-
Kenyon, C.1
-
56
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
Kenyon C 2005 The plasticity of aging: insights from long-lived mutants. Cell 120 449-460.
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
57
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A & Tabtiang R 1993 A C. elegans mutant that lives twice as long as wild type. Nature 366 461-464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
58
-
-
0032573178
-
The genetics of caloric restriction in Caenorhabditis elegans
-
Lakowski B & Hekimi S 1998 The genetics of caloric restriction in Caenorhabditis elegans. PNAS 95 13091-13096.
-
(1998)
PNAS
, vol.95
, pp. 13091-13096
-
-
Lakowski, B.1
Hekimi, S.2
-
59
-
-
0035846601
-
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
-
Lee RY, Hench J & Ruvkun G 2001 Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Current Biology 11 1950-1957.
-
(2001)
Current Biology
, vol.11
, pp. 1950-1957
-
-
Lee, R.Y.1
Hench, J.2
Ruvkun, G.3
-
60
-
-
0037228016
-
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
-
Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J & Ruvkun G 2003 A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nature Genetics 33 40-48.
-
(2003)
Nature Genetics
, vol.33
, pp. 40-48
-
-
Lee, S.S.1
Lee, R.Y.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Ruvkun, G.6
-
61
-
-
9144264169
-
A map of the interactome network of the metazoan C. elegans
-
Li S, Armstrong CM, Bertin N, Ge H, Milstein S, Boxem M, Vidalain PO, Han JD, Chesneau A, Hao T et al. 2004 A map ofthe interactome network of the metazoan C. elegans. Science 303 540-543.
-
(2004)
Science
, vol.303
, pp. 540-543
-
-
Li, S.1
Armstrong, C.M.2
Bertin, N.3
Ge, H.4
Milstein, S.5
Boxem, M.6
Vidalain, P.O.7
Han, J.D.8
Chesneau, A.9
Hao, T.10
-
62
-
-
0037380570
-
daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway
-
Li W, Kennedy SG & Ruvkun G 2003 daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. Genes and Development 17 844-858.
-
(2003)
Genes and Development
, vol.17
, pp. 844-858
-
-
Li, W.1
Kennedy, S.G.2
Ruvkun, G.3
-
63
-
-
0345447590
-
Tissue-specific activities of C. clegans DAF-16 in the regulation of lifespan
-
Libina N, Berman JR & Kenyon C 2003 Tissue-specific activities of C. clegans DAF-16 in the regulation of lifespan. Cell 115 489-502.
-
(2003)
Cell
, vol.115
, pp. 489-502
-
-
Libina, N.1
Berman, J.R.2
Kenyon, C.3
-
64
-
-
0034967720
-
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
-
Lin K, Hsin H, Libina N & Kenyon C 2001 Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nature Genetics 28 139-145.
-
(2001)
Nature Genetics
, vol.28
, pp. 139-145
-
-
Lin, K.1
Hsin, H.2
Libina, N.3
Kenyon, C.4
-
65
-
-
4444304350
-
A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging
-
Ludewig AH, Kober-Eisermann C, Weitzel C, Bethke A, Neubert K, Gerisch B, Hutter H & Antebi A 2004 A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging. Genes and Development 18 2120-2133.
-
(2004)
Genes and Development
, vol.18
, pp. 2120-2133
-
-
Ludewig, A.H.1
Kober-Eisermann, C.2
Weitzel, C.3
Bethke, A.4
Neubert, K.5
Gerisch, B.6
Hutter, H.7
Antebi, A.8
-
66
-
-
2342428206
-
Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450
-
Mak HY & Ruvkun G 2004 Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450. Development 131 1777-1786.
-
(2004)
Development
, vol.131
, pp. 1777-1786
-
-
Mak, H.Y.1
Ruvkun, G.2
-
67
-
-
33644616841
-
Polygenic control of Caenorhabditis elegans fat storage
-
Mak HY, Nelson LS, Basson M, Johnson CD & Ruvkun G 2006 Polygenic control of Caenorhabditis elegans fat storage. Nature Genetics 38 363-368.
-
(2006)
Nature Genetics
, vol.38
, pp. 363-368
-
-
Mak, H.Y.1
Nelson, L.S.2
Basson, M.3
Johnson, C.D.4
Ruvkun, G.5
-
68
-
-
6944246368
-
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression
-
Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkun G et al. 2004 MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nature Genetics 36 1079-1083.
-
(2004)
Nature Genetics
, vol.36
, pp. 1079-1083
-
-
Mansfield, J.H.1
Harfe, B.D.2
Nissen, R.3
Obenauer, J.4
Srineel, J.5
Chaudhuri, A.6
Farzan-Kashani, R.7
Zuker, M.8
Pasquinelli, A.E.9
Ruvkun, G.10
-
69
-
-
0042631524
-
Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
-
McElwee J, Bubb K & Thomas JH 2003 Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2 111-121.
-
(2003)
Aging Cell
, vol.2
, pp. 111-121
-
-
McElwee, J.1
Bubb, K.2
Thomas, J.H.3
-
70
-
-
7244238167
-
Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
-
McElwee JJ, Schuster E, Blanc E, Thomas JH & Gems D 2004 Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. Journal of Biological Chemistry 279 44533-44543.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 44533-44543
-
-
McElwee, J.J.1
Schuster, E.2
Blanc, E.3
Thomas, J.H.4
Gems, D.5
-
71
-
-
4344632329
-
Deletion ofthe intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans
-
Meissner B, Boll M, Daniel H & Baumeister R 2004 Deletion ofthe intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans. Journal of Biological Chemistry 279 36739-36745.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 36739-36745
-
-
Meissner, B.1
Boll, M.2
Daniel, H.3
Baumeister, R.4
-
72
-
-
0034284973
-
Extension of life-span with superoxide dismutase/catalase mimetics
-
Melov S, Ravenscroft J, Malik S, Gill MS, Walker DW, Clayton PE, Wallace DC, Malfroy B, Doctrow SR & Lithgow GJ 2000 Extension of life-span with superoxide dismutase/catalase mimetics. Science 289 1567-1569.
-
(2000)
Science
, vol.289
, pp. 1567-1569
-
-
Melov, S.1
Ravenscroft, J.2
Malik, S.3
Gill, M.S.4
Walker, D.W.5
Clayton, P.E.6
Wallace, D.C.7
Malfroy, B.8
Doctrow, S.R.9
Lithgow, G.J.10
-
73
-
-
0742323000
-
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones
-
Morley JF & Morimoto RI 2004 Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Molecular Biology of the Cell 15 657-664.
-
(2004)
Molecular Biology of the Cell
, vol.15
, pp. 657-664
-
-
Morley, J.F.1
Morimoto, R.I.2
-
74
-
-
0029768753
-
A phosphatidyhnositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
-
Morris JZ, Tissenbaum HA & Ruvkun G 1996 A phosphatidyhnositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382 536-539.
-
(1996)
Nature
, vol.382
, pp. 536-539
-
-
Morris, J.Z.1
Tissenbaum, H.A.2
Ruvkun, G.3
-
75
-
-
33646042547
-
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans
-
Motola DL, Cummins CL, Rottiers V, Sharma KK, Li T, Li Y, Suino-Powell K, Xu HE, Auchus RJ, Antebi A et al. 2006 Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell 124 1209-1223.
-
(2006)
Cell
, vol.124
, pp. 1209-1223
-
-
Motola, D.L.1
Cummins, C.L.2
Rottiers, V.3
Sharma, K.K.4
Li, T.5
Li, Y.6
Suino-Powell, K.7
Xu, H.E.8
Auchus, R.J.9
Antebi, A.10
-
77
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H & Kenyon C 2003 Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424 277-283.
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
78
-
-
0032238299
-
The C. elegans; PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
-
Ogg S & Ruvkun G 1998 The C. elegans; PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. Molecular Cell 2 887-893.
-
(1998)
Molecular Cell
, vol.2
, pp. 887-893
-
-
Ogg, S.1
Ruvkun, G.2
-
79
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA & Ruvkun G 1997 The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389 994-999.
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
Ruvkun, G.7
-
80
-
-
15444371989
-
JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
-
Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ & Tissenbaum HA 2005 JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. PNAS 102 4494-4499.
-
(2005)
PNAS
, vol.102
, pp. 4494-4499
-
-
Oh, S.W.1
Mukhopadhyay, A.2
Svrzikapa, N.3
Jiang, F.4
Davis, R.J.5
Tissenbaum, H.A.6
-
81
-
-
0032529189
-
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
-
Paradis S & Ruvkun G 1998 Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes and Development 12 2488-2498.
-
(1998)
Genes and Development
, vol.12
, pp. 2488-2498
-
-
Paradis, S.1
Ruvkun, G.2
-
82
-
-
0033151613
-
A PDK1 homolog is necessary and sufficient to transduce AGE-1 P13 kinase signals that regulate diapause in Caenorhabditis elegans
-
Paradis S, Ailion M, Toker A, Thomas JH & Ruvkun G 1999 A PDK1 homolog is necessary and sufficient to transduce AGE-1 P13 kinase signals that regulate diapause in Caenorhabditis elegans. Genes and Development 13 1438-1452.
-
(1999)
Genes and Development
, vol.13
, pp. 1438-1452
-
-
Paradis, S.1
Ailion, M.2
Toker, A.3
Thomas, J.H.4
Ruvkun, G.5
-
83
-
-
0035868890
-
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family
-
Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, Buchman AR, Ferguson KC, Heller J, Platt DM, Pasquinelli AA et al. 2001 Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes and Development 15 672-686.
-
(2001)
Genes and Development
, vol.15
, pp. 672-686
-
-
Pierce, S.B.1
Costa, M.2
Wisotzkey, R.3
Devadhar, S.4
Homburger, S.A.5
Buchman, A.R.6
Ferguson, K.C.7
Heller, J.8
Platt, D.M.9
Pasquinelli, A.A.10
-
84
-
-
0036119219
-
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1
-
Radimerski T, Montagne J, Rintelen F, Stocker H, van der Kaay J, Downes CP, Hafen E & Thomas G 2002 dS6K-regulated cell growth is dPKB/ dPI(3)K-independent, but requires dPDK1. Nature of Cell Biology 4 251-255.
-
(2002)
Nature of Cell Biology
, vol.4
, pp. 251-255
-
-
Radimerski, T.1
Montagne, J.2
Rintelen, F.3
Stocker, H.4
van der Kaay, J.5
Downes, C.P.6
Hafen, E.7
Thomas, G.8
-
85
-
-
23044445756
-
A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
-
Rea SL, Wu D, Cypser JR, Vaupel JW & Johnson TE 2005 A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nature Genetics 37 894-898.
-
(2005)
Nature Genetics
, vol.37
, pp. 894-898
-
-
Rea, S.L.1
Wu, D.2
Cypser, J.R.3
Vaupel, J.W.4
Johnson, T.E.5
-
86
-
-
0038708337
-
C. elegans ORFeome version 1.1: Experimental verification of the genome annotation and resource for proteome-scale protein expression
-
Reboul J, Vaglio F, Rual JF, Lamesch P, Martinez M, Armstrong CM, Li S, Jacotot L, Bertin N, Janky R et al. 2003 C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Nature Genetics 34 35-41.
-
(2003)
Nature Genetics
, vol.34
, pp. 35-41
-
-
Reboul, J.1
Vaglio, F.2
Rual, J.F.3
Lamesch, P.4
Martinez, M.5
Armstrong, C.M.6
Li, S.7
Jacotot, L.8
Bertin, N.9
Janky, R.10
-
87
-
-
33645527191
-
Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase
-
Rottiers V, Motola DL, Gerisch B, Cummins CL, Nishiwaki K, Mangelsdorf DJ & Antebi A 2006 Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. Developmental Cell 10 473-482.
-
(2006)
Developmental Cell
, vol.10
, pp. 473-482
-
-
Rottiers, V.1
Motola, D.L.2
Gerisch, B.3
Cummins, C.L.4
Nishiwaki, K.5
Mangelsdorf, D.J.6
Antebi, A.7
-
88
-
-
0036710840
-
Mammalian peptide transporters as targets for drug delivery
-
Rubio-Aliaga I & Daniel H 2002 Mammalian peptide transporters as targets for drug delivery. Trends in Pharmacology Science 23 434-440.
-
(2002)
Trends in Pharmacology Science
, vol.23
, pp. 434-440
-
-
Rubio-Aliaga, I.1
Daniel, H.2
-
89
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T & Hall MN 2000 TOR, a central controller of cell growth. Cell 103 253-262.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
90
-
-
0034670132
-
Structure and expression of daf-12: A nuclear hormone receptor with three isoforms that are involved in development and aging in Caenorhabditis elegans
-
Snow MI & Larsen PL 2000 Structure and expression of daf-12: a nuclear hormone receptor with three isoforms that are involved in development and aging in Caenorhabditis elegans. Biochimica et Biophysica Acta 1494 104-116.
-
(2000)
Biochimica Et Biophysica Acta
, vol.1494
, pp. 104-116
-
-
Snow, M.I.1
Larsen, P.L.2
-
91
-
-
0031468610
-
Analysis of protein domain families in Caenorhabditis elegans
-
Sonnhammer EL & Durbin R 1997 Analysis of protein domain families in Caenorhabditis elegans. Genomics 46 200-216.
-
(1997)
Genomics
, vol.46
, pp. 200-216
-
-
Sonnhammer, E.L.1
Durbin, R.2
-
92
-
-
27944506923
-
A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress
-
Springer W, Hoppe T, Schmidt E & Baumeister R 2005 A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress. Human Molecular Genetics 14 3407-3423.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 3407-3423
-
-
Springer, W.1
Hoppe, T.2
Schmidt, E.3
Baumeister, R.4
-
94
-
-
0037470501
-
The endocrine regulation of aging by insuhn-like signals
-
Tatar M, Bartke A & Antebi A 2003 The endocrine regulation of aging by insuhn-like signals. Science 299 1346-1351.
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
95
-
-
0033968037
-
Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
-
Tavernarakis N, Wang SL, Dorovkov M, Ryazanov A & Driscoll M 2000 Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes. Nature Genetics 24 180-183.
-
(2000)
Nature Genetics
, vol.24
, pp. 180-183
-
-
Tavernarakis, N.1
Wang, S.L.2
Dorovkov, M.3
Ryazanov, A.4
Driscoll, M.5
-
96
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA & Guarente L 2001 Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
97
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
-
van der Horst A, Tertoolen LG, de Vries-Smits LM, Frye RA, Medema RH & Burgering BM 2004 FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). Journal of Biological Chemistry 279 28873-28879.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 28873-28879
-
-
van der Horst, A.1
Tertoolen, L.G.2
de Vries-Smits, L.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.6
-
98
-
-
0642367846
-
Influence of TOR kinase on lifespan in C. elegans
-
Vellai T, Takacs-Vellai K, Zhang Y, Kovacs A, Orosz L & Muller F 2003 Influence of TOR kinase on lifespan in C. elegans. Nature 426 620.
-
(2003)
Nature
, vol.426
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.4
Orosz, L.5
Muller, F.6
-
99
-
-
27644585190
-
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
-
Viswanathan M, Kim SK, Berdichevsky A & Guarente L 2005 A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Development and Cell 9 605-615.
-
(2005)
Development and Cell
, vol.9
, pp. 605-615
-
-
Viswanathan, M.1
Kim, S.K.2
Berdichevsky, A.3
Guarente, L.4
-
100
-
-
0034614678
-
Protein interaction mapping in C. elegans using proteins involved in vulval development
-
Walhout AJ, Sordella R, Lu X, Hardey JL, Temple GF, Brasch MA, Thierry-Mieg N & Vidal M 2000 Protein interaction mapping in C. elegans using proteins involved in vulval development. Science 287 116-122.
-
(2000)
Science
, vol.287
, pp. 116-122
-
-
Walhout, A.J.1
Sordella, R.2
Lu, X.3
Hardey, J.L.4
Temple, G.F.5
Brasch, M.A.6
Thierry-Mieg, N.7
Vidal, M.8
-
102
-
-
28244475950
-
Overlapping and distinct functions for a C. elegans SIR2 and DAF-l6/FOXO
-
Wang Y & Tissenbaum HA 2006 Overlapping and distinct functions for a C. elegans SIR2 and DAF-l6/FOXO. Mechanisms ofl Ageing and Development 127 48-56.
-
(2006)
Mechanisms of Ageing and Development
, vol.127
, pp. 48-56
-
-
Wang, Y.1
Tissenbaum, H.A.2
-
104
-
-
0034613164
-
Regulation of C. elegans life-span by insulin-like signaling in the nervous system
-
Wolkow CA, Kimura KD, Lee MS & Ruvkun G 2000 Regulation of C. elegans life-span by insulin-like signaling in the nervous system. Science 290 147-150.
-
(2000)
Science
, vol.290
, pp. 147-150
-
-
Wolkow, C.A.1
Kimura, K.D.2
Lee, M.S.3
Ruvkun, G.4
-
105
-
-
0346668317
-
Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway
-
Wolkow C, Munoz M, Riddle D & Ruvkun G 2002 Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway. Journal of Biological Chemistry 277 49591-49597.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 49591-49597
-
-
Wolkow, C.1
Munoz, M.2
Riddle, D.3
Ruvkun, G.4
-
106
-
-
31744438846
-
Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
-
Wook Oh S, Mukhopadhyay A, Dixit BL, Raha T, Green MR & Tissenbaum HA 2006 Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nature Genetics 38 251-257.
-
(2006)
Nature Genetics
, vol.38
, pp. 251-257
-
-
Wook Oh, S.1
Mukhopadhyay, A.2
Dixit, B.L.3
Raha, T.4
Green, M.R.5
Tissenbaum, H.A.6
-
107
-
-
16344384026
-
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
-
Yang Y, Hou H, Haller EM, Nicosia SV & Bai W 2005a Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO Journal 24 1021-1032.
-
(2005)
EMBO Journal
, vol.24
, pp. 1021-1032
-
-
Yang, Y.1
Hou, H.2
Haller, E.M.3
Nicosia, S.V.4
Bai, W.5
-
108
-
-
26444489693
-
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
-
Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S et al. 2005b Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. PNAS 102 13670-13675.
-
(2005)
PNAS
, vol.102
, pp. 13670-13675
-
-
Yang, Y.1
Gehrke, S.2
Haque, M.E.3
Imai, Y.4
Kosek, J.5
Yang, L.6
Beal, M.F.7
Nishimura, I.8
Wakamatsu, K.9
Ito, S.10
-
109
-
-
0026726186
-
Protein oxidation associated with aging is reduced by dietary restriction of protein or calories
-
Youngman LD, Park JY & Ames BN 1992 Protein oxidation associated with aging is reduced by dietary restriction of protein or calories. PNAS 89 9112-9116.
-
(1992)
PNAS
, vol.89
, pp. 9112-9116
-
-
Youngman, L.D.1
Park, J.Y.2
Ames, B.N.3
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