Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway

Current Biology

Volumn 11, Issue 24, 2001, Pages 1950-1957

  Lee, Raymond Y N ^b   Hench, Jürgen ^c   Ruvkun, Gary ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c Sonnhalde 31   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS;

EID: 0035846601     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00595-4     Document Type: Article

References (24)

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3. The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
4. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
5. daf-2, daf-16 and daf-23: Genetically interacting genes controlling dauer formation in Caenorhabditis elegans
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8. Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans
9. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
10. Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
11. Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
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16. Environmental factors and gene activities that influence life span
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18. Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family
19. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
20. Synchronous growth and aging of C. elegans in the presence of fluorodeoxyuridine
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23. Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily
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