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Volumn 126, Issue 1, 2005, Pages 139-145

Automated assays to study longevity in C. elegans

Author keywords

Automation; C. elegans; daf 2; Genetics; Insulin signalling; pep 2; TOR signalling

Indexed keywords

INSULIN; TARGET OF RAPAMYCIN KINASE;

EID: 10944262345     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2004.09.010     Document Type: Conference Paper
Times cited : (24)

References (42)
  • 1
    • 0037020044 scopus 로고    scopus 로고
    • Identification of TOR signaling complexes: More TORC for the cell growth engine
    • R.T. Abraham Identification of TOR signaling complexes: more TORC for the cell growth engine Cell 111 2002 9 12
    • (2002) Cell , vol.111 , pp. 9-12
    • Abraham, R.T.1
  • 4
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • M. Bluher, B.B. Kahn, and C.R. Kahn Extended longevity in mice lacking the insulin receptor in adipose tissue Science 299 2003 572 574
    • (2003) Science , vol.299 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 5
    • 0028788935 scopus 로고
    • The 70 kDa S6 kinase: Regulation of a kinase with multiple roles in mitogenic signalling
    • M.M. Chou, and J. Blenis The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling Curr. Opin. Cell Biol. 7 1995 806 814
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 806-814
    • Chou, M.M.1    Blenis, J.2
  • 7
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • C. Couillault, N. Pujol, J. Reboul, L. Sabatier, J.F. Guichou, Y. Kohara, and J.J. Ewbank TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM Nat. Immunol. 5 2004 488 494
    • (2004) Nat. Immunol. , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.F.5    Kohara, Y.6    Ewbank, J.J.7
  • 8
    • 0037174629 scopus 로고    scopus 로고
    • Timing requirements for insulin/IGF-1 signaling in C. elegans
    • A. Dillin, D.K. Crawford, and C. Kenyon Timing requirements for insulin/IGF-1 signaling in C. elegans Science 298 2002 830 834
    • (2002) Science , vol.298 , pp. 830-834
    • Dillin, A.1    Crawford, D.K.2    Kenyon, C.3
  • 9
  • 11
    • 0031685525 scopus 로고    scopus 로고
    • Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
    • D. Gems, A.J. Sutton, M.L. Sundermeyer, P.S. Albert, K.V. King, M.L. Edgley, P.L. Larsen, and D.L. Riddle Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans Genetics 150 1998 129 155
    • (1998) Genetics , vol.150 , pp. 129-155
    • Gems, D.1    Sutton, A.J.2    Sundermeyer, M.L.3    Albert, P.S.4    King, K.V.5    Edgley, M.L.6    Larsen, P.L.7    Riddle, D.L.8
  • 12
    • 11144355021 scopus 로고    scopus 로고
    • C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span
    • M. Hertweck, C. Gobel, and R. Baumeister C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span Dev. Cell 6 2004 577 588
    • (2004) Dev. Cell , vol.6 , pp. 577-588
    • Hertweck, M.1    Gobel, C.2    Baumeister, R.3
  • 13
    • 4544311861 scopus 로고    scopus 로고
    • The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
    • Jia, K., Chen, D., Riddle, D.L., 2004. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development.
    • (2004) Development
    • Jia, K.1    Chen, D.2    Riddle, D.L.3
  • 14
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • R.S. Kamath, and A.G. Fraser Systematic functional analysis of the Caenorhabditis elegans genome using RNAi Nature 421 2003 231 237
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1    Fraser, A.G.2
  • 15
    • 3042648746 scopus 로고    scopus 로고
    • Regulation of life span in Drosophila by modulation of genes in the TOR signaling pathway
    • P. Kapahi, B.M. Zid, T. Harper, D. Koslover, V. Sapin, and S. Benzer Regulation of life span in Drosophila by modulation of genes in the TOR signaling pathway Curr. Biol. 14 2004 885 890
    • (2004) Curr. Biol. , vol.14 , pp. 885-890
    • Kapahi, P.1    Zid, B.M.2    Harper, T.3    Koslover, D.4    Sapin, V.5    Benzer, S.6
  • 16
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type [see comments]
    • C. Kenyon, J. Chang, E. Gensch, A. Rudner, and R. Tabtiang A C. elegans mutant that lives twice as long as wild type [see comments] Nature 366 1993 461 464
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 17
    • 0030813398 scopus 로고    scopus 로고
    • Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • K.D. Kimura, H.A. Tissenbaum, Y. Liu, and G. Ruvkun daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans Science 277 1997 942 946
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 18
    • 0028930267 scopus 로고
    • Genes that regulate both development and longevity in Caenorhabditis elegans
    • P.L. Larsen, P.S. Albert, and D.L. Riddle Genes that regulate both development and longevity in Caenorhabditis elegans Genetics 139 1995 1567 1583
    • (1995) Genetics , vol.139 , pp. 1567-1583
    • Larsen, P.L.1    Albert, P.S.2    Riddle, D.L.3
  • 19
    • 0037466652 scopus 로고    scopus 로고
    • DAF-16 target genes that control C. elegans life span and metabolism
    • S.S. Lee, S. Kennedy, A.C. Tolonen, and G. Ruvkun DAF-16 target genes that control C. elegans life span and metabolism Science 300 2003 644 647
    • (2003) Science , vol.300 , pp. 644-647
    • Lee, S.S.1    Kennedy, S.2    Tolonen, A.C.3    Ruvkun, G.4
  • 20
    • 0029116848 scopus 로고
    • Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
    • D. Levitan, and I. Greenwald Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene Nature 377 1995 351 354
    • (1995) Nature , vol.377 , pp. 351-354
    • Levitan, D.1    Greenwald, I.2
  • 21
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C. elegans DAF-16 in the regulation of life span
    • N. Libina, J.R. Berman, and C. Kenyon Tissue-specific activities of C. elegans DAF-16 in the regulation of life span Cell 115 2003 489 502
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 22
    • 0030657540 scopus 로고    scopus 로고
    • Daf-16: An HNF-3/forkhead family member that can function to double the life span of Caenorhabditis elegans
    • K. Lin, J.B. Dorman, A. Rodan, and C. Kenyon daf-16: an HNF-3/forkhead family member that can function to double the life span of Caenorhabditis elegans Science 278 1997 1319 1322
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 23
    • 0028981288 scopus 로고
    • Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans
    • C.D. Link Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans Proc. Natl. Acad. Sci. U.S.A. 92 1995 9368 9372
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 9368-9372
    • Link, C.D.1
  • 24
    • 0028280285 scopus 로고
    • A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans
    • E.A. Malone, and J.H. Thomas A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans Genetics 136 1994 879 886
    • (1994) Genetics , vol.136 , pp. 879-886
    • Malone, E.A.1    Thomas, J.H.2
  • 25
    • 4344632329 scopus 로고    scopus 로고
    • Deletion of the intestinal peptide transporter affects insulin and TOR signaling in C. elegans
    • B. Meissner, M. Boll, H. Daniel, and R. Baumeister Deletion of the intestinal peptide transporter affects insulin and TOR signaling in C. elegans J. Biol. Chem. 279 2004 36739 36745
    • (2004) J. Biol. Chem. , vol.279 , pp. 36739-36745
    • Meissner, B.1    Boll, M.2    Daniel, H.3    Baumeister, R.4
  • 26
    • 0029768753 scopus 로고    scopus 로고
    • A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
    • J.Z. Morris, H.A. Tissenbaum, and G. Ruvkun A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans Nature 382 1996 536 539
    • (1996) Nature , vol.382 , pp. 536-539
    • Morris, J.Z.1    Tissenbaum, H.A.2    Ruvkun, G.3
  • 27
    • 0037288286 scopus 로고    scopus 로고
    • Longevity and heat stress regulation in Caenorhabditis elegans
    • M.J. Munoz Longevity and heat stress regulation in Caenorhabditis elegans Mech. Aging Dev. 124 2003 43 48
    • (2003) Mech. Aging Dev. , vol.124 , pp. 43-48
    • Munoz, M.J.1
  • 30
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • S. Ogg, S. Paradis, S. Gottlieb, G.I. Patterson, L. Lee, H.A. Tissenbaum, and G. Ruvkun The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans Nature 389 1997 994 999
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5    Tissenbaum, H.A.6    Ruvkun, G.7
  • 31
    • 0033151613 scopus 로고    scopus 로고
    • A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
    • S. Paradis, M. Ailion, A. Toker, J.H. Thomas, and G. Ruvkun A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans Genes Dev. 13 1999 1438 1452
    • (1999) Genes Dev. , vol.13 , pp. 1438-1452
    • Paradis, S.1    Ailion, M.2    Toker, A.3    Thomas, J.H.4    Ruvkun, G.5
  • 32
    • 0032529189 scopus 로고    scopus 로고
    • Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
    • S. Paradis, and G. Ruvkun Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor Genes Dev. 12 1998 2488 2498
    • (1998) Genes Dev. , vol.12 , pp. 2488-2498
    • Paradis, S.1    Ruvkun, G.2
  • 33
    • 0035818590 scopus 로고    scopus 로고
    • Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death
    • J.A. Parker, J.B. Connolly, C. Wellington, M. Hayden, J. Dausset, and C. Neri Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death Proc. Natl. Acad. Sci. U.S.A. 98 2001 13318 13323
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 13318-13323
    • Parker, J.A.1    Connolly, J.B.2    Wellington, C.3    Hayden, M.4    Dausset, J.5    Neri, C.6
  • 34
    • 0037382586 scopus 로고    scopus 로고
    • Aging: New targets, new functions
    • G.I. Patterson Aging: new targets, new functions Curr. Biol. 13 2003 R279 R281
    • (2003) Curr. Biol. , vol.13
    • Patterson, G.I.1
  • 35
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • T. Schmelzle, and M.N. Hall TOR, a central controller of cell growth Cell 103 2000 253 262
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 36
    • 0037206901 scopus 로고    scopus 로고
    • Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans
    • P. Syntichaki, K. Xu, M. Driscoll, and N. Tavernarakis Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans Nature 419 2002 939 944
    • (2002) Nature , vol.419 , pp. 939-944
    • Syntichaki, P.1    Xu, K.2    Driscoll, M.3    Tavernarakis, N.4
  • 37
    • 0037470501 scopus 로고    scopus 로고
    • The endocrine regulation of aging by insulin-like signals
    • M. Tatar, A. Bartke, and A. Antebi The endocrine regulation of aging by insulin-like signals Science 299 2003 1346 1351
    • (2003) Science , vol.299 , pp. 1346-1351
    • Tatar, M.1    Bartke, A.2    Antebi, A.3
  • 38
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life span and impairs neuroendocrine function
    • M. Tatar, A. Kopelman, D. Epstein, M.P. Tu, C.M. Yin, and R.S. Garofalo A mutant Drosophila insulin receptor homolog that extends life span and impairs neuroendocrine function Science 292 2001 107 110
    • (2001) Science , vol.292 , pp. 107-110
    • Tatar, M.1    Kopelman, A.2    Epstein, D.3    Tu, M.P.4    Yin, C.M.5    Garofalo, R.S.6
  • 40
    • 0033621115 scopus 로고    scopus 로고
    • Thermal avoidance in Caenorhabditis elegans: An approach to the study of nociception
    • N. Wittenburg, and R. Baumeister Thermal avoidance in Caenorhabditis elegans: an approach to the study of nociception Proc. Natl. Acad. Sci. U.S.A. 96 1999 10477 10482
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 10477-10482
    • Wittenburg, N.1    Baumeister, R.2
  • 41
    • 0036542955 scopus 로고    scopus 로고
    • Life span: Getting the signal from the nervous system
    • C.A. Wolkow Life span: getting the signal from the nervous system Trends Neurosci. 25 2002 212 216
    • (2002) Trends Neurosci. , vol.25 , pp. 212-216
    • Wolkow, C.A.1
  • 42
    • 0034613164 scopus 로고    scopus 로고
    • Regulation of C. elegans life span by insulin-like signaling in the nervous system
    • C.A. Wolkow, K.D. Kimura, M.S. Lee, and G. Ruvkun Regulation of C. elegans life span by insulin-like signaling in the nervous system Science 290 2000 147 150
    • (2000) Science , vol.290 , pp. 147-150
    • Wolkow, C.A.1    Kimura, K.D.2    Lee, M.S.3    Ruvkun, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.