Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan

Aging Cell

Volumn 5, Issue 1, 2006, Pages 31-37

  Gami, Minaxi S ^a   Wolkow, Catherine A ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Aging; C. elegans; FOXO; Insulin; Lifespan; Phosphoinositol 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; INSULIN; PROTEIN KINASE B; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR DAF 2; UNCLASSIFIED DRUG;

CAENORHABDITIS ELEGANS; CELL GROWTH; CELL RESPIRATION; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; LARVAL DEVELOPMENT; LIFESPAN; LONGEVITY; MOLECULAR MECHANICS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DRUG EVALUATION, PRECLINICAL; HUMANS; INSULIN; LONGEVITY; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; INVERTEBRATA;

EID: 33644798225     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2006.00188.x     Document Type: Review

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