High-throughput and parallel screening methods in asymmetric hydrogenation

Chemical Reviews

Volumn 106, Issue 7, 2006, Pages 2912-2942

  Jäkel, Christoph ^a   Paciello, Rocco ^a  

^a BASF SE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST SELECTIVITY; CATALYSTS; CRYSTALLIZATION; HYDROGEN BONDS; MOLECULAR STRUCTURE; SCREENING; SYNTHESIS (CHEMICAL);

CATALYTIC IDENTIFICATION; ENANTIOSELECTIVE SYNTHESIS; PARALLEL SCREENING METHODS; ROUTE SELECTION;

HYDROGENATION;

DRUG; LIGAND;

CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG DESIGN; DRUG INDUSTRY; HYDROGENATION; INSTRUMENTATION; METHODOLOGY; REVIEW; STEREOISOMERISM; SYNTHESIS;

COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; DRUG INDUSTRY; HYDROGENATION; LIGANDS; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; STEREOISOMERISM;

EID: 33746881704     PISSN: 00092665     EISSN: None     Source Type: Journal    
DOI: 10.1021/cr040675a     Document Type: Review

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313. 3 s/c 200/1, 98.3% ee; in dichloroethane 99.3% ee and an s/c ratio of 1000/1.