Rapid identification of enantioselective ketone reductions using targeted microbial libraries

Tetrahedron

Volumn 60, Issue 3, 2004, Pages 789-797

  Homann, Michael J ^a   Vail, Robert B ^a   Previte, Edward ^a   Tamarez, Maria ^a   Morgan, Brian ^a,b   Dodds, David R ^a,c   Zaks, Aleksey ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b DIVERSA CORPORATION   (United States)

^c Dodds and Associates LLC   (United States)

Author keywords

Chiral alcohols; Enantioselective reductions; Ketone reduction; Microbial bioconversion

Indexed keywords

1 ACETONAPHTHONE; 1 PHENYL 1 PROPANOL; 1 PHENYL 2 BUTANONE; 1 PHENYL 3 BUTANOL; 1 PHENYLETHANOL; 1 TETRALONE; 2 ACETONAPHTHONE; 2,2 DIMETHYLPROPIOPHENONE; 4' CHLOROACETOPHENONE; 4' FLUOROACETOPHENONE; 4' FLUOROPROPIOPHENONE; 4' METHOXACETOPHENONE; 4' METHOXYPROPIOPHENONE; 4' METHYLACETOPHENONE; 4' METHYLPROPIOPHENONE; 4' NITROACETOPHENONE; ACETOPHENONE; ALCOHOL DERIVATIVE; ALKYL ARYL KETONE; ALPHA TETRALOL; BENZYLACETONE; BUTYROPHENONE; ISOBUTYROPHENONE; KETONE DERIVATIVE; PROPIOPHENONE; UNCLASSIFIED DRUG; VALEROPHENONE;

ARTICLE; BACTERIUM CULTURE; BIOTECHNOLOGICAL PROCEDURES; BIOTRANSFORMATION; CONTROLLED STUDY; ENANTIOMER; ENANTIOSELECTIVITY; FUNGUS CULTURE; MICROORGANISM; NONHUMAN; OPTICAL ROTATION; OXIDATION; PRIORITY JOURNAL; REDUCTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; YEAST;

EID: 0348225170     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.10.123     Document Type: Article

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