Synthesis of a β-amino acid pharmacophore via a β-lactam intermediate

Journal of Organic Chemistry

Volumn 70, Issue 5, 2005, Pages 1949-1952

  Angelaud, Rémy ^a   Zhong, Yong Li ^a   Maligres, Peter ^a   Lee, Jaemoon ^a   Askin, David ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

AMINO ACIDS PHARMACOPHORE; BETA;-LACTEME; STEREOSELECTIVE SYNTHESIS;

AMINO ACIDS;

BETA AMINO ACID; BETA LACTAM; N BOC 4 (2,5 DIFLUOROPHENYL)3 AMINOBUTANOIC ACID; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; PHARMACOPHORE;

ACYLATION; AMINO ACIDS; BETA-LACTAMS; DRUG DESIGN; MOLECULAR CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 14544301880     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048249c     Document Type: Article

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