Asymmetric synthesis of an MMP-3 inhibitor incorporating a 2-alkyl succinate motif

Organic Process Research and Development

Volumn 7, Issue 3, 2003, Pages 362-368

  Ashcroft, Christopher P ^a   Challenger, Stephen ^a   Derrick, Andrew M ^a   Storey, Richard ^a   Thomson, Nicholas M ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; ITACONIC ACID; PHOSPHINE; PHOSPHONOSUCCINATE; PROPIONALDEHYDE; STROMELYSIN INHIBITOR; SUCCINIC ACID DERIVATIVE; TOLUENE DERIVATIVE; UK 370 106; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CATALYSIS; CHEMICAL MODIFICATION; CHEMICAL REACTION; CRYSTAL; CRYSTALLIZATION; DRUG SYNTHESIS; ENANTIOMER; HYDROGEN BOND; HYDROGENATION; OLEFINATION;

EID: 0037708568     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op034001y     Document Type: Article

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