Diastereoselective hydrogenation of 4-(phosphonomethyl)-2-pyridinecarboxylic acid

Topics in Catalysis

Volumn 13, Issue 3, 2000, Pages 191-194

  Steiner, H ^a   Giannousis, P ^a   Pische Jacques, A ^a   Blaser, H U ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Diastereoselective hydrogenation; Mixed metal catalyst; Palladium rhodium; Substituted pyridines

Indexed keywords

EID: 0001525184     PISSN: 10225528     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009069913798     Document Type: Article

References (7)

1. A.J. Hutchison, M. Williams, Ch. Angst, R. de Jesus, L. Blanchard, R.H. Jackson, E.J. Wilusz, D.E. Murphy, P.S. Bernard, J. Schneider, T. Campbell, W. Guida and M.A. Sills, J. Med. Chem. 32 (1989) 2171.
2. P. Giannousis, J. Carlson and M. Leimer, in: Process Chemistry in the Pharmaceutical Industry, ed. K.G. Gadamasetti (Dekker, New York, 1999) p. 173.
3. PL. Ornstein, J.M. Schauss, J.W. Chambers, D.L. Huser, J.D. Leander, D.T. Wong, J.W. Paschal, N.D. Jones and J.B. Deeter, J. Med. Chem. 32 (1989) 827.
4. M. Freifelder, Practical Catalytic Hydrogenation (Wiley, New York, 1971) p. 587.
5. M. Bartok, Stereochemistry of Heterogeneous Metal Catalysis (Wiley, New York, 1985) p. 481.
6. M. Freifelder, J. Org. Chem. 26 (1991) 3805;
7. M. Freifelder, J. Org. Chem. 27 (1962) 284, 4046.